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International Journal of Legal Medicine

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01.09.2013 | Original Article

Preliminary results on the postmortem measurement of 3-beta-hydroxybutyrate in liver homogenates

verfasst von: Cristian Palmiere, Patrice Mangin, Dominique Werner

Erschienen in: International Journal of Legal Medicine | Ausgabe 5/2013

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Abstract

The concentrations of 3-beta-hydroxybutyrate (3HB) in blood and two liver samples were retrospectively examined in a series of medicolegal autopsies. These cases included diabetic ketoacidosis, nondiabetic individuals presenting moderate to severe decompositional changes and nondiabetic medicolegal cases privy of decompositional changes. 3HB concentrations in liver sample homogenates correlate well with blood values in all examined groups. Additionally, decompositional changes were not associated with increases in blood and liver 3HB levels. These results suggest that 3HB can be reliably measured in liver homogenates when blood is not available at autopsy. Furthermore, they suggest that metabolic disturbances potentially leading or contributing to death may be objectified through liver 3HB determination even in decomposed bodies.

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Titel: Preliminary results on the postmortem measurement of 3-beta-hydroxybutyrate in liver homogenates
verfasst von: Cristian Palmiere
Patrice Mangin
Dominique Werner
Publikationsdatum: 01.09.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: International Journal of Legal Medicine / Ausgabe 5/2013
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-013-0870-3

Springer Medizin

Preliminary results on the postmortem measurement of 3-beta-hydroxybutyrate in liver homogenates

Abstract

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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