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Journal of Neural Transmission

Erschienen in:

11.09.2018 | High Impact Review in Neuroscience, Neurology or Psychiatry - Review Article

Prenatal stress and enhanced developmental plasticity

verfasst von: Sarah Hartman, Jay Belsky

Erschienen in: Journal of Neural Transmission | Ausgabe 12/2018

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Abstract

Two separate lines of inquiry indicate (a) that prenatal stress is associated with heightened behavioral and physiological reactivity, and (b) that these postnatal phenotypes are associated with increased susceptibility to both positive and negative developmental experiences and environmental exposures. This research considered together raises the intriguing hypothesis first advanced by Pluess and Belsky (Dev Psychopathol 23:29–38, 2011) that prenatal-stress fosters, promotes or “programs” postnatal developmental plasticity. In this paper, we review further evidence consistent with this proposition, including a novel animal study which experimentally manipulated both prenatal stress and postnatal rearing. Directions for future work focused on mechanisms mediating the plasticity-inducing effects of prenatal stress and the moderators of such effects are outlined.

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Titel: Prenatal stress and enhanced developmental plasticity
verfasst von: Sarah Hartman
Jay Belsky
Publikationsdatum: 11.09.2018
Verlag: Springer Vienna
Erschienen in: Journal of Neural Transmission / Ausgabe 12/2018
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-018-1926-9

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