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24.09.2018 | Psychiatry and Preclinical Psychiatric Studies - Short communication

Desacylghrelin but not acylghrelin is reduced during smoking cessation

verfasst von: Mahsa Ardeshiripur, Mathias Rhein, Helge Frieling, Stefan Bleich, Thomas Hillemacher, Marc Muschler, Alexander Glahn

Erschienen in: Journal of Neural Transmission | Ausgabe 12/2018

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Abstract

This study focused on the acetylation status of ghrelin examining acyl- and desacylghrelin and its effect on craving during 14 days of smoking abstinence. This is the first study demonstrating changes in desacylghrelin plasma levels in smokers compared to non-smokers while there was no difference of acylated ghrelin. Future studies should specifically refer to plasma ghrelin as either desacyl- or acylghrelin since both have different effects on tobacco-seeking behavior and the underlying physiology.

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Titel: Desacylghrelin but not acylghrelin is reduced during smoking cessation
verfasst von: Mahsa Ardeshiripur
Mathias Rhein
Helge Frieling
Stefan Bleich
Thomas Hillemacher
Marc Muschler
Alexander Glahn
Publikationsdatum: 24.09.2018
Verlag: Springer Vienna
Erschienen in: Journal of Neural Transmission / Ausgabe 12/2018
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-018-1930-0

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Desacylghrelin but not acylghrelin is reduced during smoking cessation

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