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Social Psychiatry and Psychiatric Epidemiology
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 12/2018

25.09.2018 | Invited Review

Primary prevention of dementia: from modifiable risk factors to a public brain health agenda?

verfasst von: Felix S. Hussenoeder, Steffi G. Riedel-Heller

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 12/2018

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Abstract

Introduction

With large numbers of people affected, no treatment in sight and continuing demographic change, the prevention of dementia is becoming a central public health issue.

Methods

We conducted a systematic meta-review including systematic reviews and meta-analyses of longitudinal observational studies on modifiable risk and protective factors for dementia published over the last 5 years.

Results

Compelling evidence on a number of modifiable risk factors, mostly lifestyle factors, is available from longitudinal observational studies to inform primary preventive efforts.

Discussion

Evidence stemming from preventive RCTs is limited. However, multi-domain interventions addressing a variety of risk factors at once seem promising with regard to high-risk individuals (selective preventive approach). However, we argue that it is time to move forward and discuss a public brain health agenda as a universal preventive approach. Based on a risk reduction strategy, the public brain health agenda suggests the following ten key actions: (1) increase physical activity, (2) foster social integration, (3) improve education and foster lifelong learning, (4) provide mentally stimulating workplaces, (5) foster a cognitively active lifestyle, (6) propose a healthy Mediterranean-like diet, (7) reduce alcohol consumption, (8) stop smoking, (9) prevent, diagnose and treat chronic conditions, and (10) reduce anticholinergic medication in the elderly.
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Metadaten
Titel
Primary prevention of dementia: from modifiable risk factors to a public brain health agenda?
verfasst von
Felix S. Hussenoeder
Steffi G. Riedel-Heller
Publikationsdatum
25.09.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 12/2018
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-018-1598-7

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