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15.04.2024 | Review

Putting More Weight on Obesity Trials in Heart Failure

verfasst von: Josephine Harrington, Naveed Sattar, G Michael Felker, James L. Januzzi, Carolyn S. P. Lam, Neha J. Pagidipati, Ambarish Pandey, Harriette G. C. Van Spall, Darren K. McGuire

Erschienen in: Current Heart Failure Reports | Ausgabe 3/2024

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Abstract

Purpose of Review

To review ongoing and planned clinical trials of weight loss among individuals with or at high risk of heart failure.

Recent Findings

Intentional weight loss via semaglutide among persons with heart failure and preserved ejection fraction and obesity significantly improves weight loss and health status as assessed by the KCCQ-CSS score and is associated with improvements in 6-min walk test.

Summary

Ongoing and planned trials will explore the role of intentional weight loss with treatments such as semaglutide or tirzepatide for individuals with heart failure across the entire ejection fraction spectrum.

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Titel: Putting More Weight on Obesity Trials in Heart Failure
verfasst von: Josephine Harrington
Naveed Sattar
G Michael Felker
James L. Januzzi
Carolyn S. P. Lam
Neha J. Pagidipati
Ambarish Pandey
Harriette G. C. Van Spall
Darren K. McGuire
Publikationsdatum: 15.04.2024
Verlag: Springer US
Erschienen in: Current Heart Failure Reports / Ausgabe 3/2024
Print ISSN: 1546-9530
Elektronische ISSN: 1546-9549
DOI: https://doi.org/10.1007/s11897-024-00655-z

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Putting More Weight on Obesity Trials in Heart Failure