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European Radiology

Erschienen in:

19.11.2021 | Musculoskeletal

Quantitative T2 mapping of the sacroiliac joint cartilage at 3T in patients with axial spondyloarthropathies

verfasst von: Suleyman Kasar, Mesut Ozturk, Ahmet Veysel Polat

Erschienen in: European Radiology | Ausgabe 2/2022

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Abstract

Objective

To evaluate the diagnostic value of T2 mapping of sacroiliac joint cartilage in patients with axial spondyloarthropathies (SpA).

Methods

Thirty-seven SpA patients and 43 controls (mean age: 36.5 ± 8.2; 20 men) prospectively underwent conventional MRI and T2 mapping of the sacroiliac joints at 3 T. SpA patients and their sacroiliac joints were categorized into active and inactive based on the presence of bone marrow edema on the conventional MRI. T2-relaxation times were measured by drawing six manual ROIs on the cartilaginous part of the joints. T2 values of the bilateral iliac and sacral joint cartilages for each patient (T2_subject), iliac and sacral cartilages for each sacroiliac joint (T2_joint), iliac cartilage (T2_iliac), and sacral cartilage (T2_sacral) were calculated and compared between SpA patients and controls, and active and inactive joints.

Results

The T2_subject of SpA patients (50.48 ± 5.32 ms) was significantly higher than the T2_subject of the controls (46.33 ± 3.30 ms, p < 0.001). Selecting an optimal T2_subject cut-off value of 48.77 to differentiate SpA patients from controls revealed a sensitivity and a specificity of 62.2% and 81.4% respectively (AUC = 0.739). In SpA patients, T2_joint, T2_iliac, and T2_sacral values of the inactive joints were not significantly different from those of the active joints (p = 0.088, p = 0.179, and p = 0.069). T2_joint, T2_iliac, and T2_sacral values of the inactive joints of SpA patients were significantly higher than those of the controls (p = 0.012, p = 0.029, and p = 0.016).

Conclusions

T2 values of both active and inactive sacroiliac joint cartilages of SpA patients were increased. Thus, T2 mapping may be used in the diagnosis of SpA.

Key Points

• Sacroiliac cartilage T2 values of SpA patients increase compared to those of the non-SpA controls.

• Sacroiliac cartilage T2 values of active and inactive joints of SpA patients increase compared to those of the non-SpA controls.

• Sacroiliac cartilage T2 values of active and inactive joints of SpA patients do not show statistically significant difference.

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Titel: Quantitative T2 mapping of the sacroiliac joint cartilage at 3T in patients with axial spondyloarthropathies
verfasst von: Suleyman Kasar
Mesut Ozturk
Ahmet Veysel Polat
Publikationsdatum: 19.11.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 2/2022
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-021-08357-z

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Springer Medizin

Quantitative T2 mapping of the sacroiliac joint cartilage at 3T in patients with axial spondyloarthropathies

Abstract

Objective

Methods

Results

Conclusions

Key Points

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