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Current Psychiatry Reports
Erschienen in: Current Psychiatry Reports 4/2015

01.04.2015 | Personality Disorders (C Schmahl, Section Editor)

Recent Advances in the Developmental Aspects of Borderline Personality Disorder

verfasst von: Carla Sharp, Sohye Kim

Erschienen in: Current Psychiatry Reports | Ausgabe 4/2015

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Abstract

The aim of the current paper was to review the most recent advances in the developmental aspects of borderline personality disorder (BPD) over the last 3 years to highlight the most significant trends in the field. In so doing, we identify and discuss two exciting new trends: (a) an emphasis on the biological basis of adolescent BPD and (b) empirical evidence in support of long-held theories of the development of BPD. Together, these trends suggest that for the first time, empirical findings are beginning to emerge in support of complex and reciprocal biology × environment interactions over time in the development of BPD. We discuss the emerging literature and highlight the translational impact of this work for the assessment and intervention of adolescent BPD.
Literatur
1.
Sharp C, Tackett JL. Introduction: an idea whose time has come. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014. p. 3–8.CrossRef
2.
Robins E, Guze SB. Establishment of diagnostic validity in psychiatric illness—its application to schizophrenia. A J Psychiatry. 1970;126(7):983–7.CrossRef
3.
Michonski J. The underlying factor structure of DSM criteria in youth BPD. In: Sharp C, Tackett J, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014.
4.
Carlson EA, Egeland B, Sroufe LA. A prospective investigation of the development of borderline personality symptoms. Dev Psychopathol. 2009;21(4):1311–34.CrossRefPubMed
5.
Sharp C et al. Theory of mind and emotion regulation difficulties in adolescents with borderline traits. J Am Acad Child Adolesc Psychiatry. 2011;50(6):563–73.CrossRefPubMed
6.
Chanen AM, Jovev M, Jackson HJ. Adaptive functioning and psychiatric symptoms in adolescents with borderline personality disorder. J Clin Psychiatry. 2007;68(2):297–306.CrossRefPubMed
7.
Chanen AM et al. Two-year stability of personality disorder in older adolescent outpatients. J Pers Disord. 2004;18(6):526–41.CrossRefPubMed
8.
Bornovalova MA et al. Stability, change, and heritability of borderline personality disorder traits from adolescence to adulthood: a longitudinal twin study. Dev Psychopathol. 2009;21(4):1335–53.CrossRefPubMedCentralPubMed
9.
Cohen P et al. Socioeconomic background and the developmental course of schizotypal and borderline personality disorder symptoms. Dev Psychopathol. 2008;20(2):633–50.CrossRefPubMed
10.
Distel MA et al. Heritability of borderline personality disorder features is similar across three countries. Psychol Med. 2008;38(9):1219–29.CrossRefPubMed
11.
Michonski JD et al. An item response theory analysis of the DSM-IV borderline personality disorder criteria in a population-based sample of 11- to 12-year-old children. Pers Disord Theory Res Treat. 2013;4(1):15–22.CrossRef
12.
Zanarini MC et al. Prevalence of DSM-IV borderline personality disorder in two community samples: 6,330 english 11-year-olds and 34,653 american adults. J Pers Disord. 2011;25(5):607–19.CrossRefPubMed
13.
Johnson JG et al. Cumulative prevalence of personality disorders between adolescence and adulthood. Acta Psychiatr Scand. 2008;118(5):410–3.CrossRefPubMed
14.
Ha C, et al. Axis I comorbidity in hospitalized adolescents with borderline personality disorder. J Psychiatry. 2014.
15.
Levy KN et al. Concurrent and predictive validity of the personality disorder diagnosis in adolescent inpatients. A J Psychiatry. 1999;156(10):1522–8.CrossRef
16.
Miller AL, Muehlenkamp JJ, Jacobson CM. Fact or fiction: diagnosing borderline personality disorder in adolescents. Clin Psychol Rev. 2008;28(6):969–81.CrossRefPubMed
17.
Chanen AM, Kaess M. Developmental pathways to borderline personality disorder. Curr Psychiatry Rep. 2012;14(1):45–53.CrossRefPubMed
18.
Distel MA et al. Heritability of borderline personality disorder features is similar across three countries. Psychol Med. 2008;38(9):1219–29.CrossRefPubMed
19.
Torgersen S et al. A twin study of personality disorders. Compr Psychiatry. 2000;41(6):416–25.CrossRefPubMed
20.
Kendler KS, Myers J, Reichborn-Kjennerud T. Borderline personality disorder traits and their relationship with dimensions of normative personality: a web-based cohort and twin study. Acta Psychiatr Scand. 2011;123(5):349–59.CrossRefPubMedCentralPubMed
21.
Belsky DW et al. Etiological features of borderline personality related characteristics in a birth cohort of 12-year-old children. Dev Psychopathol. 2012;24(1):251–65.CrossRefPubMedCentralPubMed
22.•
Hankin BL et al. Association between 5-HTTLPR and borderline personality disorder traits among youth. Front Psychiatry. 2011;2:6. This is the first molecular genetic study to date on this topic, and reported an association between 5-HTTLPR and adolescent BPD.CrossRefPubMedCentralPubMed
23.
24.
Zaboli G et al. Tryptophan hydroxylase-1 gene variants associate with a group of suicidal borderline women. Neuropsychopharmacology. 2006;31(9):1982–90.CrossRefPubMed
25.
Ni X et al. Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder. Neurosci Lett. 2006;408(3):214–9.CrossRefPubMed
26.
Ni X et al. Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study. Prog Neuro-Psychopharmacol Biol Psychiatry. 2009;33(1):128–33.CrossRef
27.
Ni X et al. Monoamine oxidase A gene is associated with borderline personality disorder. Psychiatr Genet. 2007;17(3):153–7.CrossRefPubMed
28.
Goodman M, Perez-Rodriguez M, Siever L. The neurobiology of adolescent-onset borderline personality disorder. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014. p. 113–28.CrossRef
29.
Brunner R et al. Reduced prefrontal and orbitofrontal gray matter in female adolescents with borderline personality disorder: is it disorder specific? Neuroimage. 2010;49(1):114–20.CrossRefPubMed
30.
Chanen AM et al. Orbitofrontal, amygdala and hippocampal volumes in teenagers with first-presentation borderline personality disorder. Psychiatry Res. 2008;163(2):116–25.CrossRefPubMed
31.
Goodman M et al. Anterior cingulate volume reduction in adolescents with borderline personality disorder and co-morbid major depression. J Psychiatr Res. 2011;45(6):803–7.CrossRefPubMed
32.
Chanen AM et al. Orbitofrontal, amygdala and hippocampal volumes in teenagers with first-presentation borderline personality disorder. Psychiatry Res. 2008;163(2):116–25.CrossRefPubMed
33.•
Richter J et al. Reduced cortical and subcortical volumes in female adolescents with borderline personality disorder. Psychiatry Res. 2014;221(3):179–86. This study found reduced cortical (frontal and parietal) and subcortical (hippocampal and amygdalar) volumes in female adolescents with BPD.CrossRefPubMed
34.
Takahashi T et al. Midline brain structures in teenagers with first-presentation borderline personality disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33(5):842–6.CrossRefPubMed
35.
Takahashi T, et al. Superior temporal gyrus volume in teenagers with first-presentation borderline personality disorder. Psychiatry Res.
36.
Garner B et al. Pituitary volume in teenagers with first-presentation borderline personality disorder. Psychiatry Res. 2007;156(3):257–61.CrossRefPubMed
37.
Crowell SE, Beauchaine TP, Lenzenwger MF. The development of borderline personality disorder and self-injurious behavior. In: Beauchaine TP, Hinshaw SP, editors. Child and adolescent psychopathology. Hoboken: Wiley; 2008. p. 510–39.
38.
Maier-Hein KH et al. Disorder-specific white matter alterations in adolescent borderline personality disorder. Biol Psychiatry. 2014;75(1):81–8.CrossRefPubMed
39.•
New AS et al. Developmental differences in diffusion tensor imaging parameters in borderline personality disorder. J Psychiatr Res. 2013;47(8):1101–9. This diffusion tensor imaging (DTI) study found bilateral tract-specific decreased fractional anisotropy (FA) in inferior longitudinal fasciculus (ILF) in adolescents with BPD, suggesting that the normal developmental peak in FA is not achieved in adolescent BPD.CrossRefPubMedCentralPubMed
40.
Cicchetti D, Rogosch FA. Equifinality and multifinality in developmental psychopathology. Dev Psychopathol. 1996;8:597–600.CrossRef
41.
Linehan MM. Cognitive-behavioral treatment of borderline personality disorder1993. New York: Guilford Press; 1993.
42.
Crowell SE, Beauchaine TP, Linehan MM. A biosocial developmental model of borderline personality: elaborating and extending linehan’s theory. Psychol Bull. 2009;135(3):495–510.CrossRefPubMedCentralPubMed
43.
Paris J. The development of impulsivity and suicidality in borderline personality disorder. Dev Psychopathol. 2005;17(4):1091–104.CrossRefPubMed
44.•
Arens EA et al. Testing the biosocial model of borderline personality disorder: results of a prospective 5-year longitudinal study. Personal Ment Health. 2011;5(1):29–42. This study represents one of the first attempts to empirically validate the biosocial theory of BPD, and reported that temperamental traits, in interaction with an perceived invalidating environment, predicted the risk of BPD five years later.CrossRef
45.
Gratz KL et al. Exploring the association between emotional abuse and childhood borderline personality features: the moderating role of personality traits. Behav Ther. 2011;42(3):493–508.CrossRefPubMedCentralPubMed
46.
Fonagy P, Target M, Gergely G. Attachment and borderline personality disorder. A theory and some evidence. Psychiatr Clin North Am. 2000;23(1):103–22.CrossRefPubMed
47.
Fonagy P, Luyten P. A developmental, mentalization-based approach to the understanding and treatment of borderline personality disorder. Dev Psychopathol. 2009;21(4):1355–81.CrossRefPubMed
48.
Sharp C, Fonagy P. Social cognition and attachment-related disorders. In: Sharp C, Fonagy P, Goodyer I, editors. Social cognition and developmental psychopathology. Oxford: Oxford University Press; 2008. p. 269–302.CrossRef
49.•
Sharp C. The social-cognitive basis of BPD: a theory of hypermentalizing. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014. p. 211–26. This chapter reports a multiple mediation study of inpatient adolescents that demonstrated that hypermentalizing mediated the link between attachment coherence and BPD traits.CrossRef
50.
Gunderson JG, Lyons-Ruth K. BPD’S interpersonal hypersensitivity phenotype: a gene-environment-developmental model. J Pers Disord. 2008;22(1):22–41.CrossRefPubMedCentralPubMed
51.
Zanarini MC, Frankenburg FR. The essential nature of borderline psychopathology. J Pers Disord. 2007;21(5):518–35.CrossRefPubMed
52.
Shmueli-Goetz Y et al. The Child Attachment Interview: a psychometric study of reliability and discriminant validity. Dev Psychol. 2008;44(4):939–56.CrossRefPubMed
53.
Dziobek I et al. Introducing MASC: a movie for the assessment of social cognition. J Autism Dev Disord. 2006;36(5):623–36.CrossRefPubMed
54.
Fossati A et al. Does mindfulness mediate the association between attachment dimensions and borderline personality disorder features? A study of Italian non-clinical adolescents. Attach Hum Dev. 2011;13(6):563–78.CrossRefPubMed
55.
Choi-Kain LW, Gunderson JG. Mentalization: ontogeny, assessment, and application in the treatment of borderline personality disorder. Am J Psychiatry. 2008;165(9):1127–35.CrossRefPubMed
56.
Deborde AS et al. Alexithymia as a mediator between attachment and the development of borderline personality disorder in adolescence. J Pers Disord. 2012;26(5):676–88.CrossRefPubMed
57.
Baron Cohen S et al. The “Reading the mind in the eyes” test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry. 2001;42(2):241–51.CrossRefPubMed
58.
Gratz KL, Roemer L. Multidimensional assessment of emotion regulation and dysregulation: development, factor structure and initial validation of the difficulties in emotion regulation scale. J Psychopathol Behav Assess. 2004;26(1):41–54.CrossRef
59.
Kim S, Sharp C, Carbone C. The protective role of attachment security for adolescent borderline personality disorder features via enhanced positive emotion regulation strategies. Pers Disord Theory Res Treat. 2014;5(2):125–36.CrossRef
60.••
Bornovalova MA et al. Tests of a direct effect of childhood abuse on adult borderline personality disorder traits: a longitudinal discordant twin design. J Abnorm Psychol. 2013;122(1):180–94. Using a longitudinal twin design, this study found support for a genetic mediation model wherein the link between child abuse and BPD stemmed from common genetic risk factors. These findings are inconsistent with the model in which child abuse directly causes BPD.CrossRefPubMedCentralPubMed
61.••
Belsky DW et al. Etiological features of borderline personality related characteristics in a birth cohort of 12-year-old children. Dev Psychopathol. 2012;24(1):251–65. This longitudinal study of same-sex twins found that personal exposure to harsh treatment in the family environment predicted the development of BPD features at age 12, showing evidence of environmental mediation. This association was stronger in the presence of a family history of psychiatric illness, consistent with diathesis–stress models of borderline etiology.CrossRefPubMedCentralPubMed
62.••
Cicchetti D et al. Moderation of maltreatment effects on childhood borderline personality symptoms by gender and oxytocin receptor and FK506 binding protein 5 genes. Dev Psychopathol. 2014;26(3):831–49. This study of maltreated and non-maltreated children found gene-environment-gender interaction effects in predicting childhood BPD. A diathesis-stress model was supported among girls, whereas differential-sensitivity interaction effect was found among boys.CrossRefPubMed
63.
Sharp C, Fonagy P. Practitioner review: emergent borderline personality disorder in adolescence: recent conceptualization, intervention, and implications for clinical practice. J Child Psychol Psychiatry. under review.
64.
Belsky J. The development of human reproductive strategies: progress and prospects. Curr Dir Psychol Scie. 2012;21(5):310–6.CrossRef
65.
Fonagy P, Luyten P. A multilevel perspective on the development of borderline personality disorder. In: Cicchetti D, editor. Development and psychopathology. New York: Wiley; 2015.
66.
Beauchaine TP et al. Multifinality in the development of personality disorders: a biology x sex x environment interaction model of antisocial and borderline traits. Dev Psychopathol. 2009;21(3):735–70.CrossRefPubMedCentralPubMed
67.
Depue RA, Lenzenweger MF. A neurobehavioral dimensional model of personality disturbance. In: Lenzenweger MF, Clarkin JF, editors. Major theories of personality disorder. New York: Guilford Press; 2005. p. 391–453.
68.
Fonagy P, Luyten P, Strathearn L. Borderline personality disorder, mentalization, and the neurobiology of attachment. Infant Ment Health J. 2011;32(1):47–69.CrossRef
69.
Luyten P, Blatt SJ. Integrating theory-driven and empirically-derived models of personality development and psychopathology: a proposal for DSM V. Clin Psychol Rev. 2011;31(1):52–68.CrossRefPubMed
70.
Westen D et al. Personality diagnoses in adolescence: DSM-IV axis II diagnoses and an empirically derived alternative. Am J Psychiatry. 2003;160(5):952–66.CrossRefPubMed
71.
Stepp SD, Whalen DJ, Pedersen SL. The externalizing pathway to borderline personality disorder in youth. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014. p. 247–64.CrossRef
72.
Sharp C, Kalpakci A. If it walks like a duck and talks like a duck: evaluating the validity of borderline personality disorder in adolescents. Scand J Child Adolesc Psychol Psychiatry. under review.
73.
74.
Fonagy P et al. Mentalization-based treatment for adolescents with borderline traits. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children and adolescents. New York: Springer; 2014. p. 313–32.CrossRef
75.
Miller AL, Carnesale MT, Courtne EA. Dialectical behavior therapy. In: Sharp C, Tackett JL, editors. Handbook of borderline personality disorder in children in adolescents. New York: Springer; 2014. p. 385–401.CrossRef
76.
Rossouw TI, Fonagy P. Mentalization-based treatment for self-harm in adolescents: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry. 2012;51(12):1304–13.CrossRefPubMed
77.
Mehlum L et al. Dialectical behavior therapy for adolescents with repeated suicidal and self-harming behavior: a randomized trial. J Am Acad Child Adolesc Psychiatry. 2014;53(10):1082–91.CrossRefPubMed
78.
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington: American Psychiatric Association; 2013.CrossRef
79.
National Institute for Health and Clinical Excellence. Borderline personality disorder: treatment and management. Clinical guideline 78. London: National Institute for Health and Clinical Excellence; 2009.
Metadaten
Titel
Recent Advances in the Developmental Aspects of Borderline Personality Disorder
verfasst von
Carla Sharp
Sohye Kim
Publikationsdatum
01.04.2015
Verlag
Springer US
Erschienen in
Current Psychiatry Reports / Ausgabe 4/2015
Print ISSN: 1523-3812
Elektronische ISSN: 1535-1645
DOI
https://doi.org/10.1007/s11920-015-0556-2

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