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Virchows Archiv

Erschienen in:

15.10.2018 | Review and Perspectives

Recent advances in the histological and molecular classification of endometrial stromal neoplasms

verfasst von: Joana Ferreira, Ana Félix, Jochen K. Lennerz, Esther Oliva

Erschienen in: Virchows Archiv | Ausgabe 6/2018

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Abstract

This review addresses known features and recent developments in the histological, immunohistochemical, and molecular characterization of endometrial stromal neoplasms. We discuss the spectrum of these tumors, from the benign endometrial stromal nodule to low-grade endometrial stromal sarcoma to uterine undifferentiated sarcomas with a special emphasis on the expanding group of high-grade stromal sarcomas, recently added to the 2014 WHO classification, not only discussing the well-established YWHAE-FAM22 tumors but also two new groups, presenting with BCOR alterations including those with BCOR tandem internal duplications or NTRK fusions. It is likely that this high-grade category of endometrial stromal tumors will expand as increasing molecular data is available.

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Titel: Recent advances in the histological and molecular classification of endometrial stromal neoplasms
verfasst von: Joana Ferreira
Ana Félix
Jochen K. Lennerz
Esther Oliva
Publikationsdatum: 15.10.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Virchows Archiv / Ausgabe 6/2018
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-018-2470-6

Klimawandel und Gesundheit: Was Sie in der Hausarztpraxis wissen müssen und tun können

Springer Medizin

Recent advances in the histological and molecular classification of endometrial stromal neoplasms

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Klimawandel und Gesundheit: Was Sie in der Hausarztpraxis wissen müssen und tun können

Springer Medizin

Abstract

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