Erschienen in:
01.04.2008 | Poster presentation
Relationship between the use of polymyxin B-immobilized fiber for hemofiltration and some laboratory parameters (endocannabinoids, high mobility group box-1 protein and oxidative stress) in severe pneumonia patients
verfasst von:
K Mashiko, Y Sakamoto, T Obata, H Matsumoto, Y Hara, N Kutsukata, Y Yamamoto
Erschienen in:
Critical Care
|
Sonderheft 2/2008
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Excerpt
Septic shock remains a major cause of multiple organ failure, with a high mortality rate, and severe pneumonia is one of the major causes of septic shock. The existence of a relationship between lung injury and the serum level of F2-isoprostane, as a known oxidative stress marker, was recently reported. The technique of direct hemoperfusion (DHP) with a polymyxin B-immobilized fiber column (PMX; Toray Industries Inc., Tokyo Japan) was developed in Japan in 1994, and it has been used for the treatment of endotoxemia in septic shock. Reduction of the serum levels of several endotoxins following PMX has been recognized. …