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Erschienen in: Current Cardiovascular Risk Reports 6/2023

22.04.2023

Remote Patient Monitoring: What Have We Learned and Where Are We Going?

verfasst von: Bert Vandenberk, Satish R. Raj

Erschienen in: Current Cardiovascular Risk Reports | Ausgabe 6/2023

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Abstract

Purpose of Review

Remote monitoring (RM) of cardiac implantable electronic devices (CIEDs) is an important part of patient follow-up. The increasing number of patients with CIEDs and the recent pandemic pose several challenges for already limited device clinic resources. This review focuses on recent evolutions in RM and identifies future needs to improve RM.

Recent Findings

RM has been associated with multiple clinical benefits, including improved survival, early detection of actionable events, reduction in inappropriate shocks, longer battery lives, and more efficient healthcare utilization. The survival benefit was driven by studies using alert-based continuous RM with daily transmissions and fast reaction times. Patients report a high satisfaction rate without significant differences in quality of life between RM and in-office follow-up.
The increasing workload, due to the increasing number of CIEDs implanted with daily remote transmissions, results in several challenges for the future of RM. RM requires appropriate reimbursement for RM device clinics to optimize patient/staff ratios, including sufficient non-clinical and administrative support. Universal alert programming and data processing may minimize inter-manufacturer differences, improve the signal-to-noise ratio, and allow the development of standard operating protocols and workflows. In the future, programming by remote control and true remote programming may further improve remote CIED management, patient quality of life, and device clinic workflows.

Summary

RM should be considered standard of care in management of patients with CIEDs. The clinical benefits of RM can be maximized by an alert-based continuous RM model. Adapted healthcare policies are required to keep RM manageable for the future.
Literatur
7.•
Zurück zum Zitat Hindricks G, Varma N, Kacet S, Lewalter T, Sogaard P, Guedon-Moreau L, et al. Daily remote monitoring of implantable cardioverter-defibrillators: insights from the pooled patient-level data from three randomized controlled trials (IN-TIME, ECOST, TRUST). Eur Heart J. 2017;38(22):1749–55. https://doi.org/10.1093/eurheartj/ehx015. This meta-analysis shows the potential of remote monitoring to improve rsurvival, mainly by prevention of heart failure exacerbations.CrossRefPubMedPubMedCentral Hindricks G, Varma N, Kacet S, Lewalter T, Sogaard P, Guedon-Moreau L, et al. Daily remote monitoring of implantable cardioverter-defibrillators: insights from the pooled patient-level data from three randomized controlled trials (IN-TIME, ECOST, TRUST). Eur Heart J. 2017;38(22):1749–55. https://​doi.​org/​10.​1093/​eurheartj/​ehx015. This meta-analysis shows the potential of remote monitoring to improve rsurvival, mainly by prevention of heart failure exacerbations.CrossRefPubMedPubMedCentral
9.••
Zurück zum Zitat Parthiban N, Esterman A, Mahajan R, Twomey DJ, Pathak RK, Lau DH, et al. Remote monitoring of implantable cardioverter-defibrillators: a systematic review and meta-analysis of clinical outcomes. J Am Coll Cardiol. 2015;65(24):2591–600. https://doi.org/10.1016/j.jacc.2015.04.029. This meta-analysis demonstrates that the survival benefit associated with remote monitoring is dependent on daily remote transmissions as these allow more rapid clinical event detection.CrossRefPubMed Parthiban N, Esterman A, Mahajan R, Twomey DJ, Pathak RK, Lau DH, et al. Remote monitoring of implantable cardioverter-defibrillators: a systematic review and meta-analysis of clinical outcomes. J Am Coll Cardiol. 2015;65(24):2591–600. https://​doi.​org/​10.​1016/​j.​jacc.​2015.​04.​029. This meta-analysis demonstrates that the survival benefit associated with remote monitoring is dependent on daily remote transmissions as these allow more rapid clinical event detection.CrossRefPubMed
13.
Zurück zum Zitat Kurek A, Tajstra M, Gadula-Gacek E, Buchta P, Skrzypek M, Pyka L, et al. Impact of remote monitoring on long-term prognosis in heart failure patients in a real-world cohort: results from all-comers COMMIT-HF trial. J Cardiovasc Electrophysiol. 2017;28(4):425–31. https://doi.org/10.1111/jce.13174.CrossRefPubMed Kurek A, Tajstra M, Gadula-Gacek E, Buchta P, Skrzypek M, Pyka L, et al. Impact of remote monitoring on long-term prognosis in heart failure patients in a real-world cohort: results from all-comers COMMIT-HF trial. J Cardiovasc Electrophysiol. 2017;28(4):425–31. https://​doi.​org/​10.​1111/​jce.​13174.CrossRefPubMed
14.•
Zurück zum Zitat Varma N, Piccini JP, Snell J, Fischer A, Dalal N, Mittal S. The relationship between level of adherence to automatic wireless remote monitoring and survival in pacemaker and defibrillator patients. J Am Coll Cardiol. 2015;65(24):2601–10. https://doi.org/10.1016/j.jacc.2015.04.033. In this nationwide analysis on 29471 consecutive patients, the survival benefit associated with remote monitoring was related to patient adherence, but independent of device type.CrossRefPubMed Varma N, Piccini JP, Snell J, Fischer A, Dalal N, Mittal S. The relationship between level of adherence to automatic wireless remote monitoring and survival in pacemaker and defibrillator patients. J Am Coll Cardiol. 2015;65(24):2601–10. https://​doi.​org/​10.​1016/​j.​jacc.​2015.​04.​033. In this nationwide analysis on 29471 consecutive patients, the survival benefit associated with remote monitoring was related to patient adherence, but independent of device type.CrossRefPubMed
18.
Zurück zum Zitat Versteeg H, Timmermans I, Widdershoven J, Kimman GJ, Prevot S, Rauwolf T, et al. Effect of remote monitoring on patient-reported outcomes in European heart failure patients with an implantable cardioverter-defibrillator: primary results of the REMOTE-CIED randomized trial. Europace. 2019;21(9):1360–8. https://doi.org/10.1093/europace/euz140.CrossRefPubMed Versteeg H, Timmermans I, Widdershoven J, Kimman GJ, Prevot S, Rauwolf T, et al. Effect of remote monitoring on patient-reported outcomes in European heart failure patients with an implantable cardioverter-defibrillator: primary results of the REMOTE-CIED randomized trial. Europace. 2019;21(9):1360–8. https://​doi.​org/​10.​1093/​europace/​euz140.CrossRefPubMed
19.
Zurück zum Zitat Leppert F, Siebermair J, Wesemann U, Martens E, Sattler SM, Scholz S, et al. The INFluence of Remote monitoring on Anxiety/depRession, quality of lifE, and Device acceptance in ICD patients: a prospective, randomized, controlled, single-center trial. Clin Res Cardiol. 2021;110(6):789–800. https://doi.org/10.1007/s00392-020-01667-0.CrossRefPubMed Leppert F, Siebermair J, Wesemann U, Martens E, Sattler SM, Scholz S, et al. The INFluence of Remote monitoring on Anxiety/depRession, quality of lifE, and Device acceptance in ICD patients: a prospective, randomized, controlled, single-center trial. Clin Res Cardiol. 2021;110(6):789–800. https://​doi.​org/​10.​1007/​s00392-020-01667-0.CrossRefPubMed
30.
Zurück zum Zitat Varma N, Epstein AE, Schweikert R, Michalski J, Love CJ, Investigators T. Role of automatic wireless remote monitoring immediately following ICD implant: the Lumos-T reduces routine office device follow-up study (TRUST) trial. J Cardiovasc Electrophysiol. 2016;27(3):321–6. https://doi.org/10.1111/jce.12895.CrossRefPubMed Varma N, Epstein AE, Schweikert R, Michalski J, Love CJ, Investigators T. Role of automatic wireless remote monitoring immediately following ICD implant: the Lumos-T reduces routine office device follow-up study (TRUST) trial. J Cardiovasc Electrophysiol. 2016;27(3):321–6. https://​doi.​org/​10.​1111/​jce.​12895.CrossRefPubMed
31.
33.
Zurück zum Zitat Ricci RP, Pignalberi C, Landolina M, Santini M, Lunati M, Boriani G, et al. Ventricular rate monitoring as a tool to predict and prevent atrial fibrillation-related inappropriate shocks in heart failure patients treated with cardiac resynchronisation therapy defibrillators. Heart. 2014;100(11):848–54. https://doi.org/10.1136/heartjnl-2013-305259.CrossRefPubMed Ricci RP, Pignalberi C, Landolina M, Santini M, Lunati M, Boriani G, et al. Ventricular rate monitoring as a tool to predict and prevent atrial fibrillation-related inappropriate shocks in heart failure patients treated with cardiac resynchronisation therapy defibrillators. Heart. 2014;100(11):848–54. https://​doi.​org/​10.​1136/​heartjnl-2013-305259.CrossRefPubMed
40.
Zurück zum Zitat Watanabe E, Yamazaki F, Goto T, Asai T, Yamamoto T, Hirooka K, et al. (2020) Remote management of pacemaker patients with biennial in-clinic evaluation: continuous home monitoring in the Japanese at-home study: a randomized clinical trial. Circ Arrhythm Electrophysiol. 13(5) e007734-e https://doi.org/10.1161/CIRCEP.119.007734 Watanabe E, Yamazaki F, Goto T, Asai T, Yamamoto T, Hirooka K, et al. (2020) Remote management of pacemaker patients with biennial in-clinic evaluation: continuous home monitoring in the Japanese at-home study: a randomized clinical trial. Circ Arrhythm Electrophysiol. 13(5) e007734-e https://​doi.​org/​10.​1161/​CIRCEP.​119.​007734
42.••
Zurück zum Zitat Chew DS, Piccini JP, Au F, Frazier-Mills CG, Michalski J, Varma N, et al. Alert-driven versus scheduled remote monitoring of implantable cardiac defibrillators: a cost-consequence analysis from the TRUST trial. Heart rhythm. 2022. https://doi.org/10.1016/j.hrthm.2022.12.003. This cost-consequence analysis shows that atler-driven remote monitoring was economically attractive.CrossRef Chew DS, Piccini JP, Au F, Frazier-Mills CG, Michalski J, Varma N, et al. Alert-driven versus scheduled remote monitoring of implantable cardiac defibrillators: a cost-consequence analysis from the TRUST trial. Heart rhythm. 2022. https://​doi.​org/​10.​1016/​j.​hrthm.​2022.​12.​003This cost-consequence analysis shows that atler-driven remote monitoring was economically attractive.CrossRef
43.
Zurück zum Zitat Heidbuchel H, Hindricks G, Broadhurst P, Van Erven L, Fernandez-Lozano I, Rivero-Ayerza M, et al. EuroEco (European Health Economic Trial on Home Monitoring in ICD Patients): a provider perspective in five European countries on costs and net financial impact of follow-up with or without remote monitoring. Eur Heart J. 2015;36(3):158–69. https://doi.org/10.1093/eurheartj/ehu339.CrossRefPubMed Heidbuchel H, Hindricks G, Broadhurst P, Van Erven L, Fernandez-Lozano I, Rivero-Ayerza M, et al. EuroEco (European Health Economic Trial on Home Monitoring in ICD Patients): a provider perspective in five European countries on costs and net financial impact of follow-up with or without remote monitoring. Eur Heart J. 2015;36(3):158–69. https://​doi.​org/​10.​1093/​eurheartj/​ehu339.CrossRefPubMed
44.
Zurück zum Zitat Health QO. Remote monitoring of implantable cardioverter-defibrillators, cardiac resynchronization therapy and permanent pacemakers: a health technology assessment. Ont Health Technol Assess Ser. 2018;18(7):1–199. Health QO. Remote monitoring of implantable cardioverter-defibrillators, cardiac resynchronization therapy and permanent pacemakers: a health technology assessment. Ont Health Technol Assess Ser. 2018;18(7):1–199.
45.
46.
Zurück zum Zitat Chiu CSL, Timmermans I, Versteeg H, Zitron E, Mabo P, Pedersen SS, et al. Effect of remote monitoring on clinical outcomes in European heart failure patients with an implantable cardioverter-defibrillator: secondary results of the REMOTE-CIED randomized trial. Europace . 2022;24(2):256–67. https://doi.org/10.1093/europace/euab221.CrossRefPubMed Chiu CSL, Timmermans I, Versteeg H, Zitron E, Mabo P, Pedersen SS, et al. Effect of remote monitoring on clinical outcomes in European heart failure patients with an implantable cardioverter-defibrillator: secondary results of the REMOTE-CIED randomized trial. Europace . 2022;24(2):256–67. https://​doi.​org/​10.​1093/​europace/​euab221.CrossRefPubMed
47.
Zurück zum Zitat Boriani G, Da Costa A, Quesada A, Ricci RP, Favale S, Boscolo G, et al. Effects of remote monitoring on clinical outcomes and use of healthcare resources in heart failure patients with biventricular defibrillators: results of the MORE-CARE multicentre randomized controlled trial. Eur J Heart Fail. 2017;19(3):416–25. https://doi.org/10.1002/ejhf.626.CrossRefPubMed Boriani G, Da Costa A, Quesada A, Ricci RP, Favale S, Boscolo G, et al. Effects of remote monitoring on clinical outcomes and use of healthcare resources in heart failure patients with biventricular defibrillators: results of the MORE-CARE multicentre randomized controlled trial. Eur J Heart Fail. 2017;19(3):416–25. https://​doi.​org/​10.​1002/​ejhf.​626.CrossRefPubMed
56.•
Zurück zum Zitat O’Shea CJ, Middeldorp ME, Hendriks JM, Brooks AG, Lau DH, Emami M, et al. Remote monitoring alert burden: an analysis of transmission in >26,000 patients. JACC Clin Electrophysiol. 2021;7(2):226–34. https://doi.org/10.1016/j.jacep.2020.08.029. This retrospective analysis illustrates the increasing workload of remote monitoring, predominantly generated by implantable loop recorders.CrossRefPubMed O’Shea CJ, Middeldorp ME, Hendriks JM, Brooks AG, Lau DH, Emami M, et al. Remote monitoring alert burden: an analysis of transmission in >26,000 patients. JACC Clin Electrophysiol. 2021;7(2):226–34. https://​doi.​org/​10.​1016/​j.​jacep.​2020.​08.​029This retrospective analysis illustrates the increasing workload of remote monitoring, predominantly generated by implantable loop recorders.CrossRefPubMed
58.
Zurück zum Zitat Otsuki S, Izumi D, Sakaguchi Y, Suzuki N, Hakamata T, Ikami Y, et al. Efficacy of antitachycardia pacing alert by remote monitoring of implantable cardioverter-defibrillators for out-of-hospital electrical storm. Pacing Clinical Electrophysiol. 2021;44(10):1675–82. https://doi.org/10.1111/pace.14334.CrossRefPubMed Otsuki S, Izumi D, Sakaguchi Y, Suzuki N, Hakamata T, Ikami Y, et al. Efficacy of antitachycardia pacing alert by remote monitoring of implantable cardioverter-defibrillators for out-of-hospital electrical storm. Pacing Clinical Electrophysiol. 2021;44(10):1675–82. https://​doi.​org/​10.​1111/​pace.​14334.CrossRefPubMed
66.
Zurück zum Zitat Mairesse GH, Braunschweig F, Klersy K, Cowie MR, Leyva F. Implementation and reimbursement of remote monitoring for cardiac implantable electronic devices in Europe: a survey from the health economics committee of the European Heart Rhythm Association. Europace . 2015;17(5):814–8. https://doi.org/10.1093/europace/euu390.CrossRefPubMed Mairesse GH, Braunschweig F, Klersy K, Cowie MR, Leyva F. Implementation and reimbursement of remote monitoring for cardiac implantable electronic devices in Europe: a survey from the health economics committee of the European Heart Rhythm Association. Europace . 2015;17(5):814–8. https://​doi.​org/​10.​1093/​europace/​euu390.CrossRefPubMed
71.
74.•
Zurück zum Zitat Ploux S, Strik M, Demoniere F, Rakotoarimanana D, Zemmoura A, Deplagne A, et al. (2022) Remote interrogation and reprogramming of cardiac implantable electronic devices using a custom multivendor solution. Heart rhythm : the official journal of the Heart Rhythm Society https://doi.org/10.1016/j.hrthm.2022.12.015This study describes the feasibility and safety of remote interrogations and remote programming in clinical practice by using a custom multivendor solution. Ploux S, Strik M, Demoniere F, Rakotoarimanana D, Zemmoura A, Deplagne A, et al. (2022) Remote interrogation and reprogramming of cardiac implantable electronic devices using a custom multivendor solution. Heart rhythm : the official journal of the Heart Rhythm Society https://​doi.​org/​10.​1016/​j.​hrthm.​2022.​12.​015This study describes the feasibility and safety of remote interrogations and remote programming in clinical practice by using a custom multivendor solution.
Metadaten
Titel
Remote Patient Monitoring: What Have We Learned and Where Are We Going?
verfasst von
Bert Vandenberk
Satish R. Raj
Publikationsdatum
22.04.2023
Verlag
Springer US
Erschienen in
Current Cardiovascular Risk Reports / Ausgabe 6/2023
Print ISSN: 1932-9520
Elektronische ISSN: 1932-9563
DOI
https://doi.org/10.1007/s12170-023-00720-7

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