Skip to main content
Erschienen in: Japanese Journal of Radiology 3/2017

03.02.2017 | Original Article

Respiratory gating and multifield technique radiotherapy for esophageal cancer

verfasst von: Atsushi Ohta, Motoki Kaidu, Satoshi Tanabe, Satoru Utsunomiya, Ryuta Sasamoto, Katsuya Maruyama, Kensuke Tanaka, Hirotake Saito, Toshimichi Nakano, Miki Shioi, Haruna Takahashi, Naotaka Kushima, Eisuke Abe, Hidefumi Aoyama

Erschienen in: Japanese Journal of Radiology | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To investigate the effects of a respiratory gating and multifield technique on the dose-volume histogram (DVH) in radiotherapy for esophageal cancer.

Methods and materials

Twenty patients who underwent four-dimensional computed tomography for esophageal cancer were included. We retrospectively created the four treatment plans for each patient, with or without the respiratory gating and multifield technique: No gating-2-field, No gating-4-field, Gating-2-field, and Gating-4-field plans. We compared the DVH parameters of the lung and heart in the No gating-2-field plan with the other three plans.

Result

In the comparison of the parameters in the No gating-2-field plan, there are significant differences in the Lung V5Gy, V20Gy, mean dose with all three plans and the Heart V25Gy–V40Gy with Gating-2-field plan, V35Gy, V40Gy, mean dose with No Gating-4-field plan and V30Gy–V40Gy, and mean dose with Gating-4-field plan. The lung parameters were smaller in the Gating-2-field plan and larger in the No gating-4-field and Gating-4-field plans. The heart parameters were all larger in the No gating-2-field plan.

Conclusion

The lung parameters were reduced by the respiratory gating technique and increased by the multifield technique. The heart parameters were reduced by both techniques. It is important to select the optimal technique according to the risk of complications.
Literatur
1.
Zurück zum Zitat Ishikura S, Nihei K, Ohtsu A, Boku N, Hironaka S, Mera K, et al. Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol. 2003;21:2697–702.CrossRefPubMed Ishikura S, Nihei K, Ohtsu A, Boku N, Hironaka S, Mera K, et al. Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol. 2003;21:2697–702.CrossRefPubMed
2.
Zurück zum Zitat Marks LB, Bentzen SM, Deasy JO, Kong FM, Bradley JD, Vogelius IS, et al. Radiation dose-volume effects in the lung. Int J Radiat Oncol Biol Phys. 2010;76:S70–6.CrossRefPubMedPubMedCentral Marks LB, Bentzen SM, Deasy JO, Kong FM, Bradley JD, Vogelius IS, et al. Radiation dose-volume effects in the lung. Int J Radiat Oncol Biol Phys. 2010;76:S70–6.CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Gagliardi G, Constine LS, Moiseenko V, Correa C, Pierce LJ, Allen AM, et al. Radiation dose-volume effects in the heart. Int J Radiat Oncol Biol Phys. 2010;76:S77–85.CrossRefPubMed Gagliardi G, Constine LS, Moiseenko V, Correa C, Pierce LJ, Allen AM, et al. Radiation dose-volume effects in the heart. Int J Radiat Oncol Biol Phys. 2010;76:S77–85.CrossRefPubMed
4.
Zurück zum Zitat Konski A, Li T, Christensen M, Cheng JD, Yu JQ, Crawford K, et al. Symptomatic cardiac toxicity is predicted by dosimetric and patient factors rather than changes in 18F-FDG PET determination of myocardial activity after chemoradiotherapy for esophageal cancer. Radiother Oncol. 2012;104:72–7.CrossRefPubMedPubMedCentral Konski A, Li T, Christensen M, Cheng JD, Yu JQ, Crawford K, et al. Symptomatic cardiac toxicity is predicted by dosimetric and patient factors rather than changes in 18F-FDG PET determination of myocardial activity after chemoradiotherapy for esophageal cancer. Radiother Oncol. 2012;104:72–7.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Yamashita H, Kida S, Sakumi A, Haga A, Ito S, Onoe T, et al. Four-dimensional measurement of the displacement of internal fiducial markers during 320-multislice computed tomography scanning of thoracic esophageal cancer. Int J Radiat Oncol Biol Phys. 2011;79:588–95.CrossRefPubMed Yamashita H, Kida S, Sakumi A, Haga A, Ito S, Onoe T, et al. Four-dimensional measurement of the displacement of internal fiducial markers during 320-multislice computed tomography scanning of thoracic esophageal cancer. Int J Radiat Oncol Biol Phys. 2011;79:588–95.CrossRefPubMed
6.
Zurück zum Zitat Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of respiratory motion as measured by four-dimensional computed tomography for radiation treatment planning of esophageal cancer. Int J Radiat Oncol Biol Phys. 2009;74:290–6.CrossRefPubMed Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of respiratory motion as measured by four-dimensional computed tomography for radiation treatment planning of esophageal cancer. Int J Radiat Oncol Biol Phys. 2009;74:290–6.CrossRefPubMed
7.
Zurück zum Zitat Kawaguchi G, Sasamoto R, Abe E, Ohta A, Sato H, Tanaka K, et al. The effectiveness of endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer. Radiat Oncol. 2015;10:31.CrossRefPubMedPubMedCentral Kawaguchi G, Sasamoto R, Abe E, Ohta A, Sato H, Tanaka K, et al. The effectiveness of endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer. Radiat Oncol. 2015;10:31.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Underberg RW, Lagerwaard FJ, Slotman BJ, Cuijpers JP, Senan S. Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys. 2005;62:554–60.CrossRefPubMed Underberg RW, Lagerwaard FJ, Slotman BJ, Cuijpers JP, Senan S. Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys. 2005;62:554–60.CrossRefPubMed
9.
Zurück zum Zitat Wagman R, Yorke E, Ford E, Giraud P, Mageras G, Minsky B, et al. Respiratory gating for liver tumors: use in dose escalation. Int J Radiat Oncol Biol Phys. 2003;55:659–68.CrossRefPubMed Wagman R, Yorke E, Ford E, Giraud P, Mageras G, Minsky B, et al. Respiratory gating for liver tumors: use in dose escalation. Int J Radiat Oncol Biol Phys. 2003;55:659–68.CrossRefPubMed
10.
Zurück zum Zitat Mageras GS, Pevsner A, Yorke ED, Rosenzweig KE, Ford EC, Hertanto A, et al. Measurement of lung tumor motion using respiration-correlated CT. Int J Radiat Oncol Biol Phys. 2004;60:933–41.CrossRefPubMed Mageras GS, Pevsner A, Yorke ED, Rosenzweig KE, Ford EC, Hertanto A, et al. Measurement of lung tumor motion using respiration-correlated CT. Int J Radiat Oncol Biol Phys. 2004;60:933–41.CrossRefPubMed
11.
Zurück zum Zitat Underberg RW, de van Sornsen Koste JR, Lagerwaard FJ, Vincent A, Slotman BJ, Senan S. A dosimetric analysis of respiration-gated radiotherapy in patients with stage III lung cancer. Radiat Oncol. 2006;1:8.CrossRefPubMedPubMedCentral Underberg RW, de van Sornsen Koste JR, Lagerwaard FJ, Vincent A, Slotman BJ, Senan S. A dosimetric analysis of respiration-gated radiotherapy in patients with stage III lung cancer. Radiat Oncol. 2006;1:8.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Hau E, Rains M, Browne L, Muirhead R, Yeghiaian-Alvandi R. Minimal benefit of respiratory-gated radiation therapy in the management of thoracic malignancy. J Med Imaging Radiat Oncol. 2013;57:704–12.CrossRefPubMed Hau E, Rains M, Browne L, Muirhead R, Yeghiaian-Alvandi R. Minimal benefit of respiratory-gated radiation therapy in the management of thoracic malignancy. J Med Imaging Radiat Oncol. 2013;57:704–12.CrossRefPubMed
13.
Zurück zum Zitat Muirhead R, Featherstone C, Duffton A, Moore K, McNee S. The potential clinical benefit of respiratory gated radiotherapy (RGRT) in non-small cell lung cancer (NSCLC). Radiother Oncol. 2010;95:172–7.CrossRefPubMed Muirhead R, Featherstone C, Duffton A, Moore K, McNee S. The potential clinical benefit of respiratory gated radiotherapy (RGRT) in non-small cell lung cancer (NSCLC). Radiother Oncol. 2010;95:172–7.CrossRefPubMed
14.
Zurück zum Zitat Starkschall G, Forster KM, Kitamura K, Cardenas A, Tucker SL, Stevens CW. Correlation of gross tumor volume excursion with potential benefits of respiratory gating. Int J Radiat Oncol Biol Phys. 2004;60:1291–7.CrossRefPubMed Starkschall G, Forster KM, Kitamura K, Cardenas A, Tucker SL, Stevens CW. Correlation of gross tumor volume excursion with potential benefits of respiratory gating. Int J Radiat Oncol Biol Phys. 2004;60:1291–7.CrossRefPubMed
15.
Zurück zum Zitat Kole TP, Aghayere O, Kwah J, Yorke ED, Goodman KA. Comparison of heart and coronary artery doses associated with intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys. 2012;83:1580–6.CrossRefPubMed Kole TP, Aghayere O, Kwah J, Yorke ED, Goodman KA. Comparison of heart and coronary artery doses associated with intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys. 2012;83:1580–6.CrossRefPubMed
16.
Zurück zum Zitat Qi XS, Hu A, Wang K, Newman F, Crosby M, Hu B, et al. Respiration induced heart motion and indications of gated delivery for left-sided breast irradiation. Int J Radiat Oncol Biol Phys. 2012;82:1605–11.CrossRefPubMed Qi XS, Hu A, Wang K, Newman F, Crosby M, Hu B, et al. Respiration induced heart motion and indications of gated delivery for left-sided breast irradiation. Int J Radiat Oncol Biol Phys. 2012;82:1605–11.CrossRefPubMed
17.
Zurück zum Zitat Fukada J, Shigematsu N, Takeuchi H, Ohashi T, Saikawa Y, Takaishi H, et al. Symptomatic pericardial effusion after chemoradiation therapy in esophageal cancer patients. Int J Radiat Oncol Biol Phys. 2013;87:487–93.CrossRefPubMed Fukada J, Shigematsu N, Takeuchi H, Ohashi T, Saikawa Y, Takaishi H, et al. Symptomatic pericardial effusion after chemoradiation therapy in esophageal cancer patients. Int J Radiat Oncol Biol Phys. 2013;87:487–93.CrossRefPubMed
Metadaten
Titel
Respiratory gating and multifield technique radiotherapy for esophageal cancer
verfasst von
Atsushi Ohta
Motoki Kaidu
Satoshi Tanabe
Satoru Utsunomiya
Ryuta Sasamoto
Katsuya Maruyama
Kensuke Tanaka
Hirotake Saito
Toshimichi Nakano
Miki Shioi
Haruna Takahashi
Naotaka Kushima
Eisuke Abe
Hidefumi Aoyama
Publikationsdatum
03.02.2017
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 3/2017
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-016-0606-7

Weitere Artikel der Ausgabe 3/2017

Japanese Journal of Radiology 3/2017 Zur Ausgabe

Acknowledgment

Acknowledgment

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.