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Indian Journal of Pediatrics
Erschienen in: The Indian Journal of Pediatrics 5/2014

01.05.2014 | REVIEW ARTICLE

Review of the Antenatal and Postnatal Use of Steroids

verfasst von: Julie Bartholomew, Lajos Kovacs, Apostolos Papageorgiou

Erschienen in: Indian Journal of Pediatrics | Ausgabe 5/2014

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Abstract

Antenatal and postnatal corticosteroids play an extremely important role in the management of premature infants. The antenatal administration of steroids has been universally implemented. They have not only been shown to reduce the incidence and severity of respiratory distress syndrome (RDS), but also have an impact on the incidence of intraventricular hemorrhage (IVH), patent ductus arteriosus (PDA), necrotizing enterocolitis (NEC), and possibly retinopathy of prematurity (ROP) by reducing the need for supplemental oxygen due to improved lung function. The postnatal use of dexamethasone in ventilated infants has been adopted with caution, as there have been several reports of long-term neurodevelopmental complications with this therapy. Hence, changes in dosage and indications and the search for alternative therapies has emerged. Hydrocortisone appears to be a good alternative, with reassuring long-term evaluations thus far.
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Metadaten
Titel
Review of the Antenatal and Postnatal Use of Steroids
verfasst von
Julie Bartholomew
Lajos Kovacs
Apostolos Papageorgiou
Publikationsdatum
01.05.2014
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 5/2014
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-014-1376-9

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