Introduction
Benefits of compliance with sepsis guidelines
Success with adherence to sepsis guidelines
Reasons for poor adherence
A framework for crafting a sepsis guideline
Domain 1. Scope and Purpose: | The overall aim of the guideline, the specific health questions, and the target population. |
Domain 2. Stakeholder Involvement: | The extent to which the guideline was developed by the appropriate stakeholders and represents the views of its intended users. |
Domain 3. Rigor of Development: | The process used to gather and synthesize the evidence, the methods to formulate the recommendations, and to update them. |
Domain 4. Clarity of Presentation: | The language, structure, and format of the guideline. |
Domain 5. Applicability: | The likely barriers and facilitators to implementation, strategies to improve uptake, and resource implications of applying the guideline. |
Domain 6. Editorial Independence: | The formulation of recommendations not being unduly biased with competing interests. |
Overall assessment: | Includes the rating of the overall quality of the guideline and whether the guideline would be recommended for use in practice. |