Skip to main content
Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 4/2023

01.07.2023 | Original Article

Serial Estimation of Serum Calcium and Ionic Calcium Level for Early Detection of Hypocalcemia After Total/Completion Thyroidectomy

verfasst von: Nishi Sonkhya, Shubham Agarwal, Mahaveer Prasad Choudhary, Nishant Gupta

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Ausgabe 4/2023

Einloggen, um Zugang zu erhalten

Abstract

Hypocalcemia is an important and common complication following thyroid surgery. The development of postoperative hypocalcemia is likely to be multifactorial in nature. Patients with acute hypocalcemia may present with numbness of the distal extremities, circumoral paresthesia, and/or carpopedal spasm, laryngospasm, seizure and arrhythmias. In most cases, post-thyroidectomy hypocalcemia is temporary, but small percentage (0–12%) are permanent. The present study was a 1-year prospective interventional study conducted at tertiary care center, Jaipur, India. Total 42 patients who underwent thyroidectomy were included in study. Evaluation of Serum and Ionic Calcium Level done Preoperatively and Postoperative at 6, 12, 24 and 48 h and patients who develops hypocalcemia symptoms were recorded and data were analyzed. In our study hypocalcemia was seen in 13 (31%) out of 42 subjects. Ionic calcium in ‘All patients’ gradually decreased from pre operative 1.28 ± 0.04 mmol/l to 1.14 ± 0.08 mmol/l by 24 h. Highest incidence of hypocalcemia was seen in patients who had Total thyroidectomy + neck dissection (83.3%) compared to other type of thyroid surgery. we concluded that post thyroidectomy transient hypocalcemia is a frequent complication. Serial monitoring of calcium levels preoperatively and postoperatively combined with careful monitoring of signs and symptoms of hypocalcemia is an efficient and cost-effective tool to detect early post thyroidectomy hypocalcemia.
Literatur
1.
Zurück zum Zitat Parmeggiani U, Avenia N, De Falco M et al (2005) Major complications in thyroid surgery: utility of bipolar vessel sealing (Ligasure Precise). G Chir 26(10):387–394PubMed Parmeggiani U, Avenia N, De Falco M et al (2005) Major complications in thyroid surgery: utility of bipolar vessel sealing (Ligasure Precise). G Chir 26(10):387–394PubMed
2.
Zurück zum Zitat Sciumè C, Geraci G, Pisello F et al (2006) Complications in thyroid surgery: symptomatic post-operative hypoparathyroidism incidence, surgical technique, and treatment. Ann Ital Chir 77(2):115–122PubMed Sciumè C, Geraci G, Pisello F et al (2006) Complications in thyroid surgery: symptomatic post-operative hypoparathyroidism incidence, surgical technique, and treatment. Ann Ital Chir 77(2):115–122PubMed
3.
Zurück zum Zitat Fahmy FF, Gillet D, Lolen Y, Shotton JC (2004) Management of serum calcium levels in post-thyroidectomy patients. Clin Otolaryngol 29:735–739CrossRefPubMed Fahmy FF, Gillet D, Lolen Y, Shotton JC (2004) Management of serum calcium levels in post-thyroidectomy patients. Clin Otolaryngol 29:735–739CrossRefPubMed
4.
Zurück zum Zitat Prim MP, de Diego JI, Hardisson D, Madero R, Gavilan J (2001) Factors related to nerve injury and hypocalcaemia in thyroid gland surgery. Otolaryngol Head Neck Surg 124:111–114CrossRefPubMed Prim MP, de Diego JI, Hardisson D, Madero R, Gavilan J (2001) Factors related to nerve injury and hypocalcaemia in thyroid gland surgery. Otolaryngol Head Neck Surg 124:111–114CrossRefPubMed
5.
Zurück zum Zitat Miki H, Inoue H, Kitaichi M, Masuda E, Komaki K, Monden Y (1997) Estimation of free calcium levels after thyroidectomy. J Med Invest 44:83–87PubMed Miki H, Inoue H, Kitaichi M, Masuda E, Komaki K, Monden Y (1997) Estimation of free calcium levels after thyroidectomy. J Med Invest 44:83–87PubMed
6.
Zurück zum Zitat Sturniolo G, Lo Schiavo MG, Tonante A, D’Alia C, Bonanno L (2000) Hypocalcaemia and hypoparathyroidism after total thyroidectomy: a clinical biological study and surgical considerations. Int J Surg Invest 2:99–105 Sturniolo G, Lo Schiavo MG, Tonante A, D’Alia C, Bonanno L (2000) Hypocalcaemia and hypoparathyroidism after total thyroidectomy: a clinical biological study and surgical considerations. Int J Surg Invest 2:99–105
7.
Zurück zum Zitat Jacobs JK, Aland JW Jr, Ballinger JF (1983) Total thyroidectomy: A review of 213 patients. Ann J Surg 197:542–549CrossRef Jacobs JK, Aland JW Jr, Ballinger JF (1983) Total thyroidectomy: A review of 213 patients. Ann J Surg 197:542–549CrossRef
8.
Zurück zum Zitat Glinoer D, Andry G, Chantrain G, Samil N (2000) Clinical aspects of early and late hypocalcaemia after thyroid surgery. Eur J Surg Oncol 26:571–577CrossRefPubMed Glinoer D, Andry G, Chantrain G, Samil N (2000) Clinical aspects of early and late hypocalcaemia after thyroid surgery. Eur J Surg Oncol 26:571–577CrossRefPubMed
9.
Zurück zum Zitat Sitges-Serra A, Ruiz S, Girvent M, Manjon H, Duenas JP, Sancho JJ (2010) Outcome of protracted hypo parathyroidism after total thyroidectomy. BJ Surg 97:1687–1695CrossRef Sitges-Serra A, Ruiz S, Girvent M, Manjon H, Duenas JP, Sancho JJ (2010) Outcome of protracted hypo parathyroidism after total thyroidectomy. BJ Surg 97:1687–1695CrossRef
10.
Zurück zum Zitat Gac EP, Cabané TP, Amat VJ, Huidobro GF, Rossi FR, Rodríguez FF, Ferrada VC, Cardemil RF (2007) Incidence of hypocalcemia after total thyroidectomy. Rev Med Chil 135:26–30 Gac EP, Cabané TP, Amat VJ, Huidobro GF, Rossi FR, Rodríguez FF, Ferrada VC, Cardemil RF (2007) Incidence of hypocalcemia after total thyroidectomy. Rev Med Chil 135:26–30
11.
Zurück zum Zitat Seo ST, Chang JW, Jin J, Lim YC, Rha KS, Koo BS (2015) Transient and permanent hypocalcemia after total thyroidectomy: Early predictive factors and long-term follow-up results. Surgery 158(6):1492–1499CrossRefPubMed Seo ST, Chang JW, Jin J, Lim YC, Rha KS, Koo BS (2015) Transient and permanent hypocalcemia after total thyroidectomy: Early predictive factors and long-term follow-up results. Surgery 158(6):1492–1499CrossRefPubMed
12.
Zurück zum Zitat Pisanu A, CoisA PS, Altana ML, Uccheddu A (2003) Factors predicting outcome of hypocalcaemia following total thyroidectomy. Chir Ital 55:35–40PubMed Pisanu A, CoisA PS, Altana ML, Uccheddu A (2003) Factors predicting outcome of hypocalcaemia following total thyroidectomy. Chir Ital 55:35–40PubMed
13.
Zurück zum Zitat Pfleiderer AG, Ahmad N, Draper MR et al (2009) The timing of calcium measurements in helping to predict temporary and permanent hypocalcaemia in patients having completion and total thyroidectomies. Ann R Coll Surg Engl 91(140):146 Pfleiderer AG, Ahmad N, Draper MR et al (2009) The timing of calcium measurements in helping to predict temporary and permanent hypocalcaemia in patients having completion and total thyroidectomies. Ann R Coll Surg Engl 91(140):146
14.
Zurück zum Zitat Herranz González-Botas J, Lourido PD (2013) Hipocalcemia postiroidectomía total: incidencia, control y tratamiento. Acta Otorrinolaringol Esp 64:102–107CrossRefPubMed Herranz González-Botas J, Lourido PD (2013) Hipocalcemia postiroidectomía total: incidencia, control y tratamiento. Acta Otorrinolaringol Esp 64:102–107CrossRefPubMed
15.
Zurück zum Zitat Scurry WCJ, Beus KS, Hollenbeak CS et al (2005) Perioperative parathyroid hormone assay for diagnosis and management of post thyroidectomy hypocalcemia. Laryngoscope 115:1362–1366CrossRefPubMed Scurry WCJ, Beus KS, Hollenbeak CS et al (2005) Perioperative parathyroid hormone assay for diagnosis and management of post thyroidectomy hypocalcemia. Laryngoscope 115:1362–1366CrossRefPubMed
16.
Zurück zum Zitat Moore FDJ (1994) Oral calcium supplements to enhance early hospital discharge after bilateral surgical treatment of the thyroid gland or exploration of the parathyroid glands. J Am Coll Surg 178:11–16PubMed Moore FDJ (1994) Oral calcium supplements to enhance early hospital discharge after bilateral surgical treatment of the thyroid gland or exploration of the parathyroid glands. J Am Coll Surg 178:11–16PubMed
17.
Zurück zum Zitat Marohn MR, Lacivita KA (1995) Evaluation of total/near-total thyroidectomyin a short-stay hospitalization: safe and cost effective. Surgery 118:943–947CrossRefPubMed Marohn MR, Lacivita KA (1995) Evaluation of total/near-total thyroidectomyin a short-stay hospitalization: safe and cost effective. Surgery 118:943–947CrossRefPubMed
Metadaten
Titel
Serial Estimation of Serum Calcium and Ionic Calcium Level for Early Detection of Hypocalcemia After Total/Completion Thyroidectomy
verfasst von
Nishi Sonkhya
Shubham Agarwal
Mahaveer Prasad Choudhary
Nishant Gupta
Publikationsdatum
01.07.2023
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe 4/2023
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-023-04031-6

Weitere Artikel der Ausgabe 4/2023

Indian Journal of Otolaryngology and Head & Neck Surgery 4/2023 Zur Ausgabe

Betalaktam-Allergie: praxisnahes Vorgehen beim Delabeling

16.05.2024 Pädiatrische Allergologie Nachrichten

Die große Mehrheit der vermeintlichen Penicillinallergien sind keine. Da das „Etikett“ Betalaktam-Allergie oft schon in der Kindheit erworben wird, kann ein frühzeitiges Delabeling lebenslange Vorteile bringen. Ein Team von Pädiaterinnen und Pädiatern aus Kanada stellt vor, wie sie dabei vorgehen.

Eingreifen von Umstehenden rettet vor Erstickungstod

15.05.2024 Fremdkörperaspiration Nachrichten

Wer sich an einem Essensrest verschluckt und um Luft ringt, benötigt vor allem rasche Hilfe. Dass Umstehende nur in jedem zweiten Erstickungsnotfall bereit waren, diese zu leisten, ist das ernüchternde Ergebnis einer Beobachtungsstudie aus Japan. Doch es gibt auch eine gute Nachricht.

Real-World-Daten sprechen eher für Dupilumab als für Op.

14.05.2024 Rhinosinusitis Nachrichten

Zur Behandlung schwerer Formen der chronischen Rhinosinusitis mit Nasenpolypen (CRSwNP) stehen seit Kurzem verschiedene Behandlungsmethoden zur Verfügung, darunter Biologika, wie Dupilumab, und die endoskopische Sinuschirurgie (ESS). Beim Vergleich der beiden Therapieoptionen war Dupilumab leicht im Vorteil.

Schwindelursache: Massagepistole lässt Otholiten tanzen

14.05.2024 Benigner Lagerungsschwindel Nachrichten

Wenn jüngere Menschen über ständig rezidivierenden Lagerungsschwindel klagen, könnte eine Massagepistole der Auslöser sein. In JAMA Otolaryngology warnt ein Team vor der Anwendung hochpotenter Geräte im Bereich des Nackens.

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.