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Erschienen in: European Radiology 4/2010

01.04.2010 | Head and Neck

Signal intensity change of the labyrinth in patients with surgically confirmed or radiologically diagnosed vestibular schwannoma on isotropic 3D fluid-attenuated inversion recovery MR imaging at 3 T

verfasst von: In Ho Lee, Hyung-Jin Kim, Won Ho Chung, Eunhee Kim, Jung Won Moon, Sung Tae Kim, Keon Ha Kim, Pyoung Jeon, Hong Sik Byun

Erschienen in: European Radiology | Ausgabe 4/2010

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Abstract

Objective

The purpose of this study was to evaluate the signal intensity (SI) change of the labyrinth in patients with vestibular schwannoma on isotropic 3D fluid-attenuated inversion recovery (FLAIR) imaging at 3 T.

Methods

Thirty-four patients with surgically confirmed or radiologically diagnosed vestibular schwannoma were included in this study. Retrospectively, we visually and quantitatively compared the SIs of the cochlea and vestibule on the affected side with those on the unaffected side. We also investigated whether there was correlation between the SI ratios (SIRs) of the labyrinth and the audiometric findings.

Results

On 3D FLAIR images, the SI of the cochlea and vestibule on the affected side was significantly increased in 97% (33/34) and 91% (31/34), respectively. While the SI of the cochlea was diffusely increased, that of the vestibule was only partially increased. Quantitative study also revealed statistically significantly higher SIRs of the cochlea (0.99 ± 0.29) and vestibule (0.73 ± 0.31) on the affected side, compared with the cochlea (0.47 ± 0.20) and vestibule (0.19 ± 0.10) on the unaffected side. There was no significant correlation of the SIRs of the labyrinth with the degree of hearing loss.

Conclusion

In patients with vestibular schwannoma, isotropic 3D FLAIR imaging is a useful method for the evaluation of the SI changes of the labyrinth.
Literatur
1.
Zurück zum Zitat Silverstein H, Schuknecht HF (1996) Biochemical studies of inner ear fluid in man. Changes in otosclerosis, Meniere’s disease, and acoustic neuroma. Arch Otolaryngol 84:395–402 Silverstein H, Schuknecht HF (1996) Biochemical studies of inner ear fluid in man. Changes in otosclerosis, Meniere’s disease, and acoustic neuroma. Arch Otolaryngol 84:395–402
2.
Zurück zum Zitat Silverstein H (1971) Inner ear fluid proteins in acoustic neuroma, Meniere’s disease and otosclerosis. Ann Otol Rhinol Laryngol 80:27–35PubMed Silverstein H (1971) Inner ear fluid proteins in acoustic neuroma, Meniere’s disease and otosclerosis. Ann Otol Rhinol Laryngol 80:27–35PubMed
3.
Zurück zum Zitat Silverstein H (1973) Labyrinthine tap as a diagnostic test for acoustic neurinoma. Otolaryngol Clin North Am 6:229–244PubMed Silverstein H (1973) Labyrinthine tap as a diagnostic test for acoustic neurinoma. Otolaryngol Clin North Am 6:229–244PubMed
4.
Zurück zum Zitat Thomsen J, Saxtrup O, Tos M (1982) Quantitated determination of proteins in perilymph in patients with acoustic neuromas. ORL J Otorhinolaryngol Relat Spec 44:61–65PubMed Thomsen J, Saxtrup O, Tos M (1982) Quantitated determination of proteins in perilymph in patients with acoustic neuromas. ORL J Otorhinolaryngol Relat Spec 44:61–65PubMed
5.
Zurück zum Zitat Palva T, Raunio V (1982) Cerebrospinal fluid and acoustic neurinoma specific proteins in perilymph. Acta Otolaryngol 93:201–203CrossRefPubMed Palva T, Raunio V (1982) Cerebrospinal fluid and acoustic neurinoma specific proteins in perilymph. Acta Otolaryngol 93:201–203CrossRefPubMed
6.
Zurück zum Zitat Rasmussen N, Bendtzen K, Thomsen J, Tos M (1984) Antigenicity and protein content of perilymph in acoustic neuroma patients. Acta Otolaryngol 97:502–508CrossRefPubMed Rasmussen N, Bendtzen K, Thomsen J, Tos M (1984) Antigenicity and protein content of perilymph in acoustic neuroma patients. Acta Otolaryngol 97:502–508CrossRefPubMed
7.
Zurück zum Zitat Bhadelia RA, Tedesco KL, Hwang S, Erbay SH, Lee PH, Shao W, Heilman C (2008) Increased cochlear fluid-attenuated inversion recovery signal in patients with vestibular schwannoma. AJNR Am J Neuroradiol 29:720–723CrossRefPubMed Bhadelia RA, Tedesco KL, Hwang S, Erbay SH, Lee PH, Shao W, Heilman C (2008) Increased cochlear fluid-attenuated inversion recovery signal in patients with vestibular schwannoma. AJNR Am J Neuroradiol 29:720–723CrossRefPubMed
8.
Zurück zum Zitat Kallmes DF, Hui FK, Mugler JP (2001) Suppression of cerebrospinal fluid and blood flow artifacts in FLAIR MR imaging with a single-slab three-dimensional pulse sequence: initial experience. Radiology 221:251–255CrossRefPubMed Kallmes DF, Hui FK, Mugler JP (2001) Suppression of cerebrospinal fluid and blood flow artifacts in FLAIR MR imaging with a single-slab three-dimensional pulse sequence: initial experience. Radiology 221:251–255CrossRefPubMed
9.
Zurück zum Zitat Naganawa S, Koshikawa T, Nakamura T, Kawai H, Fukatsu H, Ishigaki T, Komada T, Maruyama K, Takizawa O (2004) Comparison of flow artifacts between 2D-FLAIR and 3D-FLAIR sequences at 3 T. Eur Radiol 14:1901–1908PubMed Naganawa S, Koshikawa T, Nakamura T, Kawai H, Fukatsu H, Ishigaki T, Komada T, Maruyama K, Takizawa O (2004) Comparison of flow artifacts between 2D-FLAIR and 3D-FLAIR sequences at 3 T. Eur Radiol 14:1901–1908PubMed
10.
Zurück zum Zitat Chagla GH, Busse RF, Sydnor R, Rowley HA, Turski PA (2008) Three-dimensional fluid attenuated inversion recovery imaging with isotropic resolution and nonselective adiabatic inversion provides improved three-dimensional visualization and cerebrospinal fluid suppression compared to two-dimensional FLAIR at 3 Tesla. Invest Radiol 43:547–551CrossRefPubMed Chagla GH, Busse RF, Sydnor R, Rowley HA, Turski PA (2008) Three-dimensional fluid attenuated inversion recovery imaging with isotropic resolution and nonselective adiabatic inversion provides improved three-dimensional visualization and cerebrospinal fluid suppression compared to two-dimensional FLAIR at 3 Tesla. Invest Radiol 43:547–551CrossRefPubMed
11.
Zurück zum Zitat Barker GJ (1998) 3D fast FLAIR: a CSF-nulled 3D fast spin-echo pulse sequence. Magn Reson Imaging 16:715–720CrossRefPubMed Barker GJ (1998) 3D fast FLAIR: a CSF-nulled 3D fast spin-echo pulse sequence. Magn Reson Imaging 16:715–720CrossRefPubMed
12.
Zurück zum Zitat Tanaka N, Abe T, Kojima K, Nishimura H, Hayabuchi N (2000) Applicability and advantages of flow artifact-insensitive fluid-attenuated inversion-recovery MR sequences for imaging the posterior fossa. AJNR Am J Neuroradiol 21:1095–1098PubMed Tanaka N, Abe T, Kojima K, Nishimura H, Hayabuchi N (2000) Applicability and advantages of flow artifact-insensitive fluid-attenuated inversion-recovery MR sequences for imaging the posterior fossa. AJNR Am J Neuroradiol 21:1095–1098PubMed
13.
Zurück zum Zitat Tubridy N, Barker GJ, Macmanus DG, Moseley IF, Miller DH (1998) Three-dimensional fast fluid attenuated inversion recovery (3D fast FLAIR): a new MRI sequence which increases the detectable cerebral lesion load in multiple sclerosis. Br J Radiol 71:840–845PubMed Tubridy N, Barker GJ, Macmanus DG, Moseley IF, Miller DH (1998) Three-dimensional fast fluid attenuated inversion recovery (3D fast FLAIR): a new MRI sequence which increases the detectable cerebral lesion load in multiple sclerosis. Br J Radiol 71:840–845PubMed
14.
Zurück zum Zitat Mugler JP, Bao S, Mulkern RV, Guttmann CR, Robertson RL, Jolesz FA, Brookeman JR (2000) Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology 216:891–899PubMed Mugler JP, Bao S, Mulkern RV, Guttmann CR, Robertson RL, Jolesz FA, Brookeman JR (2000) Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology 216:891–899PubMed
15.
Zurück zum Zitat Sugiura M, Naganawa S, Teranishi M, Nakashima T (2006) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in patients with sudden sensorineural hearing loss. Laryngoscope 116:1451–1454CrossRefPubMed Sugiura M, Naganawa S, Teranishi M, Nakashima T (2006) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in patients with sudden sensorineural hearing loss. Laryngoscope 116:1451–1454CrossRefPubMed
16.
Zurück zum Zitat Otake H, Sugiura M, Naganawa S, Nakashima T (2006) 3D-FLAIR magnetic resonance imaging in the evaluation of mumps deafness. Int J Pediatr Otorhinolaryngol 70:2115–2117CrossRefPubMed Otake H, Sugiura M, Naganawa S, Nakashima T (2006) 3D-FLAIR magnetic resonance imaging in the evaluation of mumps deafness. Int J Pediatr Otorhinolaryngol 70:2115–2117CrossRefPubMed
17.
Zurück zum Zitat Sugiura M, Naganawa S, Teranishi M, Sato E, Kojima S, Nakashima T (2006) Inner ear hemorrhage in systemic lupus erythematosus. Laryngoscope 116:826–828CrossRefPubMed Sugiura M, Naganawa S, Teranishi M, Sato E, Kojima S, Nakashima T (2006) Inner ear hemorrhage in systemic lupus erythematosus. Laryngoscope 116:826–828CrossRefPubMed
18.
Zurück zum Zitat Sugiura M, Naganawa S, Sato E, Nakashima T (2006) Visualization of a high protein concentration in the cochlea of a patient with a large endolymphatic duct and sac, using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging. J Laryngol Otol 120:1084–1086CrossRefPubMed Sugiura M, Naganawa S, Sato E, Nakashima T (2006) Visualization of a high protein concentration in the cochlea of a patient with a large endolymphatic duct and sac, using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging. J Laryngol Otol 120:1084–1086CrossRefPubMed
19.
Zurück zum Zitat Sugiura M, Naganawa S, Nakata S, Kojima S, Nakashima T (2007) 3D-FLAIR MRI findings in a patient with Ramsay Hunt syndrome. Acta Otolaryngol 127:547–549CrossRefPubMed Sugiura M, Naganawa S, Nakata S, Kojima S, Nakashima T (2007) 3D-FLAIR MRI findings in a patient with Ramsay Hunt syndrome. Acta Otolaryngol 127:547–549CrossRefPubMed
20.
Zurück zum Zitat Sone M, Mizuno T, Sugiura M, Naganawa S, Hakashima T (2007) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging investigation of inner ear disturbances in cases of middle ear cholesteatoma with labyrinthine fistula. Otol Neurotol 28:1029–1033CrossRefPubMed Sone M, Mizuno T, Sugiura M, Naganawa S, Hakashima T (2007) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging investigation of inner ear disturbances in cases of middle ear cholesteatoma with labyrinthine fistula. Otol Neurotol 28:1029–1033CrossRefPubMed
21.
Zurück zum Zitat Sugiura M, Naganawa S, Sone M, Yoshida T, Nakashima T (2008) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in a patient with cochlear otosclerosis. Auris Nasus Larynx 35:269–272CrossRefPubMed Sugiura M, Naganawa S, Sone M, Yoshida T, Nakashima T (2008) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in a patient with cochlear otosclerosis. Auris Nasus Larynx 35:269–272CrossRefPubMed
22.
Zurück zum Zitat Yoshida T, Sugiura M, Naganawa S, Teranishi M, Nakata S, Nakashima T (2008) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings and prognosis in sudden sensorineural hearing loss. Laryngoscope 118:1433–1437CrossRefPubMed Yoshida T, Sugiura M, Naganawa S, Teranishi M, Nakata S, Nakashima T (2008) Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings and prognosis in sudden sensorineural hearing loss. Laryngoscope 118:1433–1437CrossRefPubMed
23.
Zurück zum Zitat Sone M, Mizuno T, Naganawa S, Nakashima T (2009) Imaging analysis in cases with inflammation-induced sensorineural hearing loss. Acta Otolaryngol 129:239–243CrossRefPubMed Sone M, Mizuno T, Naganawa S, Nakashima T (2009) Imaging analysis in cases with inflammation-induced sensorineural hearing loss. Acta Otolaryngol 129:239–243CrossRefPubMed
24.
Zurück zum Zitat Jung NY, Moon WJ, Lee MH, Chung EC (2007) Magnetic resonance cisternography: comparison between 3-dimensional driven equilibrium with sensitivity encoding and 3-dimensional balanced fast-field echo sequences with sensitivity encoding. J Comput Assist Tomogr 31:588–591CrossRefPubMed Jung NY, Moon WJ, Lee MH, Chung EC (2007) Magnetic resonance cisternography: comparison between 3-dimensional driven equilibrium with sensitivity encoding and 3-dimensional balanced fast-field echo sequences with sensitivity encoding. J Comput Assist Tomogr 31:588–591CrossRefPubMed
25.
Zurück zum Zitat Preibisch C, Pilatus U, Bunke J, Hoogenraad F, Zanella F, Lanfermann H (2003) Functional MRI using sensitivity-encoded echo planar imaging (SENSE-EPI). Neuroimage 19:412–421CrossRefPubMed Preibisch C, Pilatus U, Bunke J, Hoogenraad F, Zanella F, Lanfermann H (2003) Functional MRI using sensitivity-encoded echo planar imaging (SENSE-EPI). Neuroimage 19:412–421CrossRefPubMed
26.
Zurück zum Zitat Rydberg JN, Hammond CA, Grimm RC, Erickson BJ, Jack CR, Huston J, Riederer SJ (1994) Initial clinical experience in MR imaging of the brain with a fast fluid attenuated inversion recovery pulse sequence. Radiology 193:173–180PubMed Rydberg JN, Hammond CA, Grimm RC, Erickson BJ, Jack CR, Huston J, Riederer SJ (1994) Initial clinical experience in MR imaging of the brain with a fast fluid attenuated inversion recovery pulse sequence. Radiology 193:173–180PubMed
27.
Zurück zum Zitat Noguchi K, Ogawa T, Inugami A, Toyoshima H, Sugawara S, Hatazawa J, Fujita H, Shimosegawa E, Kanno I, Okudera T et al (1995) Acute subarachnoid hemorrhage: MR imaging with fluid-attenuated inversion recovery pulse sequences. Radiology 196:773–777PubMed Noguchi K, Ogawa T, Inugami A, Toyoshima H, Sugawara S, Hatazawa J, Fujita H, Shimosegawa E, Kanno I, Okudera T et al (1995) Acute subarachnoid hemorrhage: MR imaging with fluid-attenuated inversion recovery pulse sequences. Radiology 196:773–777PubMed
28.
Zurück zum Zitat Melhem ER, Jara H, Eustace S (1997) Fluid-attenuated inversion recovery MR imaging: identification of protein concentration thresholds for CSF hyperintensity. AJR Am J Roentgenol 169:859–62PubMed Melhem ER, Jara H, Eustace S (1997) Fluid-attenuated inversion recovery MR imaging: identification of protein concentration thresholds for CSF hyperintensity. AJR Am J Roentgenol 169:859–62PubMed
29.
Zurück zum Zitat Tan IL, Pouwels PJ, van Schijndel RA, Ader HJ, Manoliu RA, Barkhof F (2002) Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: initial experience. Eur Radiol 12:559–567PubMed Tan IL, Pouwels PJ, van Schijndel RA, Ader HJ, Manoliu RA, Barkhof F (2002) Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: initial experience. Eur Radiol 12:559–567PubMed
30.
Zurück zum Zitat Maeda M, Yagishita A, Yamamoto T, Sakuma H, Takeda K (2003) Abnormal hyperintensity within the subarachnoid space evaluated by fluid-attenuated inversion-recovery MR imaging: a spectrum of central nervous system diseases. Eur Radiol 13(Suppl 4):L192–L201CrossRefPubMed Maeda M, Yagishita A, Yamamoto T, Sakuma H, Takeda K (2003) Abnormal hyperintensity within the subarachnoid space evaluated by fluid-attenuated inversion-recovery MR imaging: a spectrum of central nervous system diseases. Eur Radiol 13(Suppl 4):L192–L201CrossRefPubMed
31.
Zurück zum Zitat Mishra AM, Reddy SJ, Husain M, Behari S, Husain N, Prasad KN, Kumar S, Gupta RK (2006) Comparison of the magnetization transfer ratio and fluid-attenuated inversion recovery imaging signal intensity in differentiation of various cystic intracranial mass lesions and its correlation with biological parameters. J Magn Reson Imaging 24:52–56CrossRefPubMed Mishra AM, Reddy SJ, Husain M, Behari S, Husain N, Prasad KN, Kumar S, Gupta RK (2006) Comparison of the magnetization transfer ratio and fluid-attenuated inversion recovery imaging signal intensity in differentiation of various cystic intracranial mass lesions and its correlation with biological parameters. J Magn Reson Imaging 24:52–56CrossRefPubMed
32.
Zurück zum Zitat Busse RF, Hariharan H, Vu A, Brittain JH (2006) Fast spin echo sequences with very long echo trains: design of variable refocusing flip angle schedules and generation of clinical T2 contrast. Magn Reson Med 55:1030–1037CrossRefPubMed Busse RF, Hariharan H, Vu A, Brittain JH (2006) Fast spin echo sequences with very long echo trains: design of variable refocusing flip angle schedules and generation of clinical T2 contrast. Magn Reson Med 55:1030–1037CrossRefPubMed
33.
Zurück zum Zitat Naganawa S, Kawai H, Fukatsu H, Ishigaki T, Komada T, Maruyama K, Takizawa O (2004) High-speed imaging at 3 Tesla: a technical and clinical review with an emphasis on whole-brain 3D imaging. Magn Reson Med Sci 3:177–187CrossRefPubMed Naganawa S, Kawai H, Fukatsu H, Ishigaki T, Komada T, Maruyama K, Takizawa O (2004) High-speed imaging at 3 Tesla: a technical and clinical review with an emphasis on whole-brain 3D imaging. Magn Reson Med Sci 3:177–187CrossRefPubMed
34.
Zurück zum Zitat Naganawa S, Komada T, Fukatsu H, Ishigaki T, Takizawa O (2006) Observation of contrast enhancement in the cochlear fluid space of healthy subjects using a 3D-FLAIR sequence at 3 Tesla. Eur Radiol 16:733–737CrossRefPubMed Naganawa S, Komada T, Fukatsu H, Ishigaki T, Takizawa O (2006) Observation of contrast enhancement in the cochlear fluid space of healthy subjects using a 3D-FLAIR sequence at 3 Tesla. Eur Radiol 16:733–737CrossRefPubMed
35.
Zurück zum Zitat Naganawa S, Sugiura M, Kawamura M, Fukatsu H, Nakashima T, Maruyama K (2006) Prompt contrast enhancement of cerebrospinal fluid space in the fundus of the internal auditory canal: observations in patients with meningeal diseases on 3D-FLAIR images at 3 Tesla. Magn Reson Med Sci 5:151–155CrossRefPubMed Naganawa S, Sugiura M, Kawamura M, Fukatsu H, Nakashima T, Maruyama K (2006) Prompt contrast enhancement of cerebrospinal fluid space in the fundus of the internal auditory canal: observations in patients with meningeal diseases on 3D-FLAIR images at 3 Tesla. Magn Reson Med Sci 5:151–155CrossRefPubMed
Metadaten
Titel
Signal intensity change of the labyrinth in patients with surgically confirmed or radiologically diagnosed vestibular schwannoma on isotropic 3D fluid-attenuated inversion recovery MR imaging at 3 T
verfasst von
In Ho Lee
Hyung-Jin Kim
Won Ho Chung
Eunhee Kim
Jung Won Moon
Sung Tae Kim
Keon Ha Kim
Pyoung Jeon
Hong Sik Byun
Publikationsdatum
01.04.2010
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 4/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-009-1626-9

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