Skip to main content
main-content

12.01.2019 | Original Article | Ausgabe 4/2019

Comparative Clinical Pathology 4/2019

Spilt bile and gallstones effect during laparoscopic cholecystectomy: an experimental study for adhesion formation

Zeitschrift:
Comparative Clinical Pathology > Ausgabe 4/2019
Autoren:
Sedigheh Tahmasebi, Shahram Jamshidi, Nader Tanideh, Mohammad Yasin Karami
Wichtige Hinweise

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Laparoscopic cholecystectomy (LC) is recognized as the standard treatment for symptomatic gallstone disease. In comparison with open techniques, LC results in a higher rate of iatrogenic biliary tract damage and spillage of bile and stones. The present study was designed to compare intraperitoneal adhesion formation following LC due to the bile and stone spillage. In this randomized experimental study, 15 dogs were randomly allocated to three groups. Each group contained five dogs. The control group underwent LC, while in the group of bile and stone spillage (BS), 5 cc of a mixture of dog bile and a sterile ground human gallstone was placed in the bed of the gallbladder following LC. The bile spillage (B) group underwent LC, followed by adding 5 cc of the bile in the bed of the gallbladder. Postsurgical adhesion formation was measured, using Nair and Zühlke classifications for inflammation, fibrosis, and neovascularization. Adhesion formation was noted in one dog from the control and B groups, whereas all animals in group 2 were found to develop high-grade adhesion. Bile cultures were negative for the control group and group B with adhesion. Based on the findings, bile spillage, as well as gallbladder stone spillage, is related to a significant increase in adhesion formation after LC. Therefore, it is necessary to avoid the bile and stone spillage.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 4/2019

Comparative Clinical Pathology 4/2019 Zur Ausgabe

Neu im Fachgebiet Pathologie

22.10.2019 | Schwerpunkt: Seltene Erkrankungen | Ausgabe 6/2019

Die IgG4-assoziierte Erkrankung

Mikroskopische Diagnose und Differenzialdiagnose

02.10.2019 | Schwerpunkt: Seltene Erkrankungen | Ausgabe 6/2019

Das un- und dedifferenzierte Endometriumkarzinom

Eine seltene Entität mit breitem differenzialdiagnostischem Spektrum