Ausgabe 4/2005
Inhalt (14 Artikel)
Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma
T. O’Reilly, M. Wartmann, S.-M. Maira, M. Hattenberger, J. Vaxelaire, M. Muller, S. Ferretti, E. Buchdunger, K.-H. Altmann, P. M. J. McSheehy
Isolated pelvic perfusion: plasma pharmacokinetics depend primarily on drug dosage and not the type of drug
James F. Belliveau, Elisabeth Arevalo, Hank Griffin, Harold J. Wanebo
A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951
Yusuke Ochi, Yoshinobu Shiose, Hiroshi Kuga, Eiji Kumazawa
Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O6-benzylguanine
Melissa L. Fishel, Michael P. Gamcsik, Shannon M. Delaney, Eleanor G. Zuhowski, Veronica M. Maher, Theodore Karrison, Robert C. Moschel, Merrill J. Egorin, M. Eileen Dolan
Endometrial K-ras mutations in postmenopausal breast cancer patients treated with adjuvant tamoxifen or toremifene
Mika Wallén, Eija Tomás, Tapio Visakorpi, Kaija Holli, Johanna Mäenpää
Interactions of carboxypeptidase G2 with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications
Georg Hempel, Rainer Lingg, Joachim Boos
Phase I study of weekly (day 1 and 8) docetaxel in combination with capecitabine in patients with advanced solid malignancies
Ramesh K. Ramanathan, Sakkaraiappan Ramalingam, Merrill J. Egorin, Chandra P. Belani, Douglas M. Potter, Marwan Fakih, Laura L. Jung, Sandra Strychor, Samuel A. Jacobs, David M. Friedland, Dong M. Shin, Gurkamal S. Chatta, Susan Tutchko, William C. Zamboni
Biochemical modulation of cytarabine triphosphate by clofarabine
Todd Cooper, Mary Ayres, Billie Nowak, Varsha Gandhi
RETRACTED ARTICLE: Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells
Hala U. Gali-Muhtasib, Mona Diab-Assaf, Makhluf J. Haddadin
Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group
Ian Judson, Peiming Ma, Bin Peng, Jaap Verweij, Amy Racine, Eugenio Donato di Paola, Martine van Glabbeke, Sasa Dimitrijevic, Michelle Scurr, Herlinde Dumez, Allan van Oosterom
Does cisplatin (CDDP) function as a modulator of 5-fluorouracil (5-FU) antitumor action? A study based on a clinical trial
Satoshi Matsusaka, Tomofumi Nagareda, Hajime Yamasaki
Gefitinib (“Iressa”, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells
Osamu Kishida, Yoshiji Miyazaki, Yoko Murayama, Miyuki Ogasa, Tamana Miyazaki, Takahiro Yamamoto, Kenji Watabe, Shusaku Tsutsui, Tatsuya Kiyohara, Iichiro Shimomura, Yasuhisa Shinomura
Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration
Ramesh R. Boinpally, Sen-Lin Zhou, Patricia M. LoRusso, Ralph E. Parchment