Ausgabe 11/2012
Inhalt (30 Artikel)
Bioinformatics for cancer immunology and immunotherapy
Pornpimol Charoentong, Mihaela Angelova, Mirjana Efremova, Ralf Gallasch, Hubert Hackl, Jerome Galon, Zlatko Trajanoski
Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells
Ryosuke Yoshida, Hiroshi Tazawa, Yuuri Hashimoto, Shuya Yano, Teppei Onishi, Tsuyoshi Sasaki, Yasuhiro Shirakawa, Hiroyuki Kishimoto, Futoshi Uno, Masahiko Nishizaki, Shunsuke Kagawa, Toshiyoshi Fujiwara
Annexin-V promotes anti-tumor immunity and inhibits neuroblastoma growth in vivo
Xiaocai Yan, Kara Doffek, Chaobo Yin, Michael Krein, Michael Phillips, Sonia L. Sugg, Bryon Johnson, Joel Shilyansky
Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease
Nicola Hardwick, Jonathan A. Ledermann, Egla Aitkens, Benny Chain
Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects
Takuya Osada, Peter Berglund, Michael A. Morse, Bolyn Hubby, Whitney Lewis, Donna Niedzwiecki, Xiao Yi Yang, Amy Hobeika, Bruce Burnett, Gayathri R. Devi, Timothy M. Clay, Jonathan Smith, H. Kim Lyerly
The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools
Satwinder Kaur Singh, Maaike Meyering, Tamara H. Ramwadhdoebe, Linda F. M. Stynenbosch, Anke Redeker, Peter J. K. Kuppen, Cornelis J. M. Melief, Marij J. P. Welters, Sjoerd H. van der Burg
Increased intratumoral IL-22-producing CD4+ T cells and Th22 cells correlate with gastric cancer progression and predict poor patient survival
Yuan Zhuang, Liu-sheng Peng, Yong-liang Zhao, Yun Shi, Xu-hu Mao, Gang Guo, Weisan Chen, Xiao-fei Liu, Jin-yu Zhang, Tao Liu, Ping Luo, Pei-wu Yu, Quan-ming Zou
Antitumor effects of Stat3-siRNA and endostatin combined therapies, delivered by attenuated Salmonella, on orthotopically implanted hepatocarcinoma
Huijie Jia, Yang Li, Tiesuo Zhao, Xin Li, Jiadi Hu, Di Yin, Baofeng Guo, Dennis J. Kopecko, Xuejian Zhao, Ling Zhang, De Qi Xu
Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccine
Hui-Ming Chen, Pi-Hsueh Wang, Swey-Shen Chen, Chih-Chun Wen, Yun-Hsiang Chen, Wen-Chin Yang, Ning-Sun Yang
Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters
Erik H. J. G. Aarntzen, I. Jolanda M. de Vries, Joop H. Göertz, Marjo Beldhuis-Valkis, Huberdina M. L. M. Brouwers, Mandy W. M. M. van de Rakt, Renate G. van der Molen, Cornelis J. A. Punt, Gosse J. Adema, Paul J. Tacken, Irma Joosten, Joannes F. M. Jacobs
Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation
Feng Qian, Jianqun Liao, Jeannine Villella, Robert Edwards, Pawel Kalinski, Shashikant Lele, Protul Shrikant, Kunle Odunsi
Controlled-rate freezer cryopreservation of highly concentrated peripheral blood mononuclear cells results in higher cell yields and superior autologous T-cell stimulation for dendritic cell-based immunotherapy
Timo Buhl, Tobias J. Legler, Albert Rosenberger, Anke Schardt, Michael P. Schön, Holger A. Haenssle
Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 phase I/II trial
Hilko Ardon, Stefaan W. Van Gool, Tina Verschuere, Wim Maes, Steffen Fieuws, Raf Sciot, Guido Wilms, Philippe Demaerel, Jan Goffin, Frank Van Calenbergh, Johan Menten, Paul Clement, Maria Debiec-Rychter, Steven De Vleeschouwer
Combining synthetic carbohydrate vaccines with cancer cell glycoengineering for effective cancer immunotherapy
Lei Qiu, Xi Gong, Qianli Wang, Jie Li, Honggang Hu, Qiuye Wu, Junping Zhang, Zhongwu Guo
Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity
Jorge Schettini, Amritha Kidiyoor, Dahlia M. Besmer, Teresa L. Tinder, Lopamudra Das Roy, Joseph Lustgarten, Sandra J. Gendler, Pinku Mukherjee
Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients
Andrés Tittarelli, Fermín E. González, Cristián Pereda, Gabriela Mora, Leonel Muñoz, Carlos Saffie, Tamara García, David Díaz, Cristián Falcón, Marcela Hermoso, Mercedes N. López, Flavio Salazar-Onfray
Uptake routes of tumor-antigen MAGE-A3 by dendritic cells determine priming of naïve T-cell subtypes
Ines Moeller, Giulio C. Spagnoli, Jürgen Finke, Hendrik Veelken, Leonora Houet
Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma
Jürgen C. Becker, Mads H. Andersen, Valeska Hofmeister-Müller, Marion Wobser, Lidia Frey, Christiane Sandig, Steffen Walter, Harpreet Singh-Jasuja, Eckhart Kämpgen, Andreas Opitz, Marc Zapatka, Eva-B. Bröcker, Per thor Straten, David Schrama, Selma Ugurel
Stratification according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by adjuvant postoperative dendritic cell vaccination
Steven De Vleeschouwer, Hilko Ardon, Frank Van Calenbergh, Raf Sciot, Guido Wilms, Johannes van Loon, Jan Goffin, Stefaan Van Gool
Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment
Sebastian Dempe, Muriel Lavie, Sofie Struyf, Rauf Bhat, Hannelien Verbeke, Stephanie Paschek, Nele Berghmans, Renate Geibig, Jean Rommelaere, Jo Van Damme, Christiane Dinsart
Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study
Runmei Li, Changli Wang, Liang Liu, Chunjuan Du, Shui Cao, Jinpu Yu, Shizhen Emily Wang, Xishan Hao, Xiubao Ren, Hui Li
HLA-DRB1*1501 and HLA-DQB1*0301 alleles are positively associated with HPV16 infection–related Kazakh esophageal squamous cell carcinoma in Xinjiang China
Jianming Hu, Ling Li, Lijuan Pang, Yunzhao Chen, Lan Yang, Chunxia Liu, Jin Zhao, Bing Chang, Yan Qi, Weihua Liang, Feng Li
Combining a peptide vaccine with oral ingestion of Lentinula edodes mycelia extract enhances anti-tumor activity in B16 melanoma-bearing mice
Kousuke Tanaka, Satoru Ishikawa, Yasunori Matsui, Takashi Kawanishi, Makoto Tamesada, Nanae Harashima, Mamoru Harada
Genetic polymorphisms in the ITPKC gene and cervical squamous cell carcinoma risk
Yuh-Cheng Yang, Tzu-Yang Chang, Tze-Chien Chen, Shih-Chuan Chang, Wei-Fang Chen, Hui-Wen Chan, Wen-Shan Lin, Fu-Ting Wu, Yann-Jinn Lee
DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8+ T-cell responses and increases PSA doubling time
Lindsey Chudley, Katy McCann, Ann Mander, Torunn Tjelle, Juan Campos-Perez, Rosemary Godeseth, Antonia Creak, James Dobbyn, Bernadette Johnson, Paul Bass, Catherine Heath, Paul Kerr, Iacob Mathiesen, David Dearnaley, Freda Stevenson, Christian Ottensmeier
B7-H3 is expressed in human hepatocellular carcinoma and is associated with tumor aggressiveness and postoperative recurrence
Tai-Wei Sun, Qiang Gao, Shuang-Jian Qiu, Jian Zhou, Xiao-Ying Wang, Yong Yi, Jie-Yi Shi, Yong-Feng Xu, Ying-Hong Shi, Kang Song, Yong-Sheng Xiao, Jia Fan
Increased tumor-infiltrating CD8+Foxp3+ T lymphocytes are associated with tumor progression in human gastric cancer
Liu-sheng Peng, Yuan Zhuang, Yun Shi, Yong-liang Zhao, Ting-ting Wang, Na Chen, Ping Cheng, Tao Liu, Xiao-fei Liu, Jin-yu Zhang, Qian-fei Zuo, Xu-hu Mao, Gang Guo, Dong-shui Lu, Pei-wu Yu, Quan-ming Zou
Molecular subtype is determinant on inflammatory status and immunological profile from invasive breast cancer patients
A. C. S. A. Herrera, C. Panis, V. J. Victorino, F. C. Campos, A. N. Colado-Simão, A. L. Cecchini, R. Cecchini
Erratum to: Induction on differentiation and modulation of bone marrow progenitor of dendritic cell by methionine enkephalin (MENK)
Jinling Liu, Wenna Chen, Jingjuan Meng, Changlong Lu, Enhua Wang, Fengping Shan