Ausgabe 8/2016
Inhalt (10 Artikel)
Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials
Vincent Madelain, Thi Huyen Tram Nguyen, Anaelle Olivo, Xavier de Lamballerie, Jérémie Guedj, Anne-Marie Taburet, France Mentré
Population Pharmacokinetics of Daclizumab High-Yield Process in Healthy Volunteers and Subjects with Multiple Sclerosis: Analysis of Phase I–III Clinical Trials
Lei Diao, Yaming Hang, Ahmed A. Othman, Ivan Nestorov, Jonathan Q. Tran
Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs
Saeed Alqahtani, Amal Kaddoumi
A Single-Dose Crossover Pharmacokinetic Comparison Study of Oral, Rectal and Topical Quetiapine in Healthy Adults
Jonathan G. Leung, Sarah Nelson, Julie L. Cunningham, Virginia H. Thompson, William V. Bobo, Simon Kung, Ross A. Dierkhising, Matthew F. Plevak, Maria I. Lapid
Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers
Laurence Gabriel, Michel Tod, Sylvain Goutelle
Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients with Atrial Tachyarrhythmias
Joe-Elie Salem, Maria El-Aissaoui, Margaux Alazard, Jean-Sébastien Hulot, Nadia Aissaoui, Jean-Yves Le-Heuzey, Christian Funck-Brentano, Christophe Faisy, Saik Urien
Drug–Drug Interactions Between the Anti-Hepatitis C Virus 3D Regimen of Ombitasvir, Paritaprevir/Ritonavir, and Dasabuvir and Eight Commonly Used Medications in Healthy Volunteers
Akshanth R. Polepally, Jennifer R. King, Bifeng Ding, Diana L. Shuster, Emily O. Dumas, Amit Khatri, Yi-Lin Chiu, Thomas J. Podsadecki, Rajeev M. Menon
Revisiting Dosing Regimen Using Pharmacokinetic/Pharmacodynamic Mathematical Modeling: Densification and Intensification of Combination Cancer Therapy
Christophe Meille, Dominique Barbolosi, Joseph Ciccolini, Gilles Freyer, Athanassios Iliadis