Ausgabe 1/2012
Inhalt (75 Artikel)
Speciation of arsenic trioxide metabolites in peripheral blood and bone marrow from an acute promyelocytic leukemia patient
Noriyoshi Iriyama, Yuta Yoshino, Bo Yuan, Akira Horikoshi, Yukio Hirabayashi, Yoshihiro Hatta, Hiroo Toyoda, Jin Takeuchi
Current management and novel agents for malignant melanoma
Byung Lee, Nikhil Mukhi, Delong Liu
Deregulation of apoptosis-related genes is associated with PRV1 overexpression and JAK2 V617F allele burden in Essential Thrombocythemia and Myelofibrosis
Raquel Tognon, Elainy PL Gasparotto, Renata P Neves, Natália S Nunes, Aline F Ferreira, Patrícia VB Palma, Simone Kashima, Dimas T Covas, Mary Santana, Elizabeth X Souto, Maria Aparecida Zanichelli, Belinda P Simões, Ana Maria de Souza, Fabíola A Castro
Recent updates on the role of microRNAs in prostate cancer
Oudai Hassan, Aamir Ahmad, Seema Sethi, Fazlul H Sarkar
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients
Sadudee Chotirat, Wanna Thongnoppakhun, Orathai Promsuwicha, Chetsada Boonthimat, Chirayu U Auewarakul
Cytogenetic and molecular predictors of response in patients with myeloid malignancies without del[5q] treated with lenalidomide
Yuka Sugimoto, Mikkael A Sekeres, Hideki Makishima, Fabiola Traina, Valeria Visconte, Anna Jankowska, Andres Jerez, Hadrian Szpurka, Christine L O'Keefe, Kathryn Guinta, Manuel Afable, Ramon Tiu, Kathy L McGraw, Alan F List, Jaroslaw Maciejewski
Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis
Jie Li, Oluwole Fadare, Li Xiang, Beihua Kong, Wenxin Zheng
Comparative mitochondrial proteomics: perspective in human diseases
Yujie Jiang, Xin Wang
MicroRNAs in B cell development and malignancy
Thilini R Fernando, Norma I Rodriguez-Malave, Dinesh S Rao
The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer
Catherine Labbaye, Ugo Testa
Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression
David Z Chang, Ying Ma, Baoan Ji, Yan Liu, Patrick Hwu, James L Abbruzzese, Craig Logsdon, Huamin Wang
Allogeneic hematopoietic stem cell transplantation in China: where we are and where to go
Meng Lv, Xiao-Jun Huang
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
Véronique Gelsi-Boyer, Mandy Brecqueville, Raynier Devillier, Anne Murati, Marie-Joelle Mozziconacci, Daniel Birnbaum
Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia
Bo Li, Sichu Liu, Yuzhe Niu, Su Fang, Xiuli Wu, Zhi Yu, Shaohua Chen, Lijian Yang, Yangqiu Li
Successful mobilization using a combination of plerixafor and G-CSF in pediatric patients who failed previous chemomobilization with G-CSF alone and possible complications of the treatment
Kyung Taek Hong, Hyoung Jin Kang, Nam Hee Kim, Min Sun Kim, Ji Won Lee, Hyery Kim, Kyung Duk Park, Hee Young Shin, Hyo Seop Ahn
Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells
Chaoquan Hu, Limin Huang, Caroline Gest, Xiaodong Xi, Anne Janin, Claudine Soria, Hong Li, He Lu
Deprivation of arginine by recombinant human arginase in prostate cancer cells
Eddy C Hsueh, Stephanie M Knebel, Wai-Hung Lo, Yun-Chung Leung, Paul Ning-Man Cheng, Chung-Tsen Hsueh
Recent advances and novel agents for gastrointestinal stromal tumor (GIST)
Gurpreet Lamba, Samir Ambrale, Byung Lee, Ridhi Gupta, Shamudheen M Rafiyath, Delong Liu
Novel human polyomaviruses, Merkel cell polyomavirus and human polyomavirus 9, in Japanese chronic lymphocytic leukemia cases
Masayuki Imajoh, Yumiko Hashida, Ayuko Taniguchi, Mikio Kamioka, Masanori Daibata
Administration of imatinib after allogeneic hematopoietic stem cell transplantation may improve disease-free survival for patients with Philadelphia chromosome-positive acute lymphobla stic leukemia
Huan Chen, Kai-yan Liu, Lan-ping Xu, Dai-hong Liu, Yu-hong Chen, Xiang-yu Zhao, Wei Han, Xiao-hui Zhang, Yu Wang, Yuan-yuan Zhang, Ya-zhen Qin, Yan-rong Liu, Xiao-jun Huang
Prediction of response to therapy with ezatiostat in lower risk myelodysplastic syndrome
Naomi Galili, Pablo Tamayo, Olga B Botvinnik, Jill P Mesirov, Margarita R Brooks, Gail Brown, Azra Raza
The significance of low PU.1 expression in patients with acute promyelocytic leukemia
Xuehua Zhu, Hui Zhang, Maoxiang Qian, Xujie Zhao, Wentao Yang, Ping Wang, Ji Zhang, Kankan Wang
Pharmacokinetics of dasatinib for Philadelphia-positive acute lymphocytic leukemia with acquired T315I mutation
Naoto Takahashi, Masatomo Miura, Stuart A Scott, Takenori Niioka, Kenichi Sawada
Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia
Yong Zou, Xudong Ma, Yiqun Huang, Lingling Hong, Jen-wei Chiao
Clinical applications of mesenchymal stem cells
Shihua Wang, Xuebin Qu, Robert Chunhua Zhao
MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status
Isabella Faraoni, Serena Laterza, Davide Ardiri, Claudia Ciardi, Francesco Fazi, Francesco Lo-Coco
Complete remission after first-line radio-chemotherapy as predictor of survival in extranodal NK/T cell lymphoma
Adrien Chauchet, Anne-Sophie Michallet, Françoise Berger, Isabelle Bedgedjian, Eric Deconinck, Catherine Sebban, Daciana Antal, Hubert Orfeuvre, Bernadette Corront, Tony Petrella, Maya Hacini, Marie Bouteloup, Gilles Salles, Bertrand Coiffier
Phase 1 dose-ranging study of ezatiostat hydrochloride in combination with lenalidomide in patients with non-deletion (5q) low to intermediate-1 risk myelodysplastic syndrome (MDS)
Azra Raza, Naomi Galili, Deborah Mulford, Scott E Smith, Gail L Brown, David P Steensma, Roger M Lyons, Ralph Boccia, Mikkael A Sekeres, Guillermo Garcia-Manero, Ruben A Mesa
Novel therapeutic agents for cutaneous T-Cell lymphoma
Salvia Jain, Jasmine Zain, Owen O’Connor
Tissue doppler echocardiography detects preclinical markers of cardiac lesion in MDS patients
Cláudio César Monteiro de Castro, Carlos Bellini Gondim Gomes, Manoel Ricardo Alves Martins, Juliana Cordeiro de Sousa, Silvia MM Magalhaes, Ronald F Pinheiro
Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness
Jarrod D Predina, Veena Kapoor, Brendan F Judy, Guanjun Cheng, Zvi Gregory Fridlender, Steven M Albelda, Sunil Singhal
Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD
Chor Sang Chim, Albert Kwok Wai Lie, Eric Yuk Tat Chan, Herman Sung Yu Liu, Ching Wa Lau, Sze Fai Yip, Joycelyn Sim, Thomas Shek-Kong Wan, Edmond Shiu-Kwan Ma, Raymond Liang, Eric Tse, Yok-Lam Kwong
Clinical and laboratory characteristics of systemic anaplastic large cell lymphoma in Chinese patients
Yan-Fang Wang, Yan-Li Yang, Zi-Fen Gao, Chun-Ju Zhou, Xylina Gregg, Yun-Fei Shi, Jing Wang, Xiao-Feng Yang, Xiao-Yan Ke
The significance of 18F-FDG PET/CT in secondary hemophagocytic lymphohistiocytosis
Li-Juan Zhang, Ji Xu, Peng Liu, Chong-Yang Ding, Jian-Yong Li, Hong-Xia Qiu, Su-Jiang Zhang
Generation and characterization of a highly effective protein substrate for analysis of FLT3 activity
Yun Chen, Yao Guo, Jiayu Han, Wanting Tina Ho, Shibo Li, Xueqi Fu, Zhizhuang Joe Zhao
Molecular functions of metallothionein and its role in hematological malignancies
Shinichiro Takahashi
Outcome of therapy-related myeloid neoplasms treated with azacitidine
Luana Fianchi, Marianna Criscuolo, Monia Lunghi, Gianluca Gaidano, Massimo Breccia, Alessandro Levis, Carlo Finelli, Valeria Santini, Pellegrino Musto, Esther N Oliva, Pietro Leoni, Antonietta Aloe Spiriti, Francesco D’Alò, Stefan Hohaus, Livio Pagano, Giuseppe Leone, Maria Teresa Voso
Effects of intensified conditioning on Epstein-Barr virus and cytomegalovirus infections in allogeneic hematopoietic stem cell transplantation for hematological malignancies
Li Xuan, Fen Huang, Zhiping Fan, Hongsheng Zhou, Xian Zhang, Guopan Yu, Yu Zhang, Can Liu, Jing Sun, Qifa Liu
Challenges to improved therapeutics for metastatic castrate resistant prostate cancer: from recent successes and failures
Xuan Huang, Cindy H Chau, William D Figg
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a tissue biomarker for detection of early Hepatocellular carcinoma in patients with cirrhosis
Yantong Guo, Jingming Zhao, Jingtao Bi, Quan Wu, Xin Wang, Quanyou Lai
Prognostic value of unrelated atypical serum immunofixation patterns during Multiple Myeloma therapy
Cristina Guimarães, Rui Bergantim, Renata Ramalho, Nuno Couto, João T Guimarães, Fernanda Trigo
Alterations in the ribosomal machinery in cancer and hematologic disorders
Niraj Shenoy, Rachel Kessel, Tushar D Bhagat, Sanchari Bhattacharyya, Yiting Yu, Christine Mcmahon, Amit Verma
Splenomegaly in myelofibrosis—new options for therapy and the therapeutic potential of Janus kinase 2 inhibitors
Jasleen Randhawa, Alen Ostojic, Radovan Vrhovac, Ehab Atallah, Srdan Verstovsek
Prognostic factors in primary diffuse large B-cell lymphoma of adrenal gland treated with rituximab-CHOP chemotherapy from the Consortium for Improving Survival of Lymphoma (CISL)
Yu Ri Kim, Jin Seok Kim, Yoo Hong Min, Dok Hyun Yoon, Ho-Jin Shin, Yeung-Chul Mun, Yong Park, Young Rok Do, Seong Hyun Jeong, Joon Seong Park, Sung Yong Oh, Suee Lee, Eun Kyung Park, Joung-Soon Jang, Won-Sik Lee, Hwe-Won Lee, HyeonSeok Eom, Jae-sook Ahn, Jae-Heon Jeong, Sun Kyung Baek, Seok Jin Kim, Won Seog Kim, Cheolwon Suh
Acute graft versus host disease after orthotopic liver transplantation
Inga Mandac Rogulj, Joachim Deeg, Stephanie J Lee
EGFR gene copy number as a predictive biomarker for the treatment of metastatic colorectal cancer with anti-EGFR monoclonal antibodies: a meta-analysis
Zu-Yao Yang, Wei-Xi Shen, Xue-Feng Hu, Da-Yong Zheng, Xin-Yin Wu, Ya-Fang Huang, Jin-Zhang Chen, Chen Mao, Jin-Ling Tang
Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia
Limin Zou, Han Zhang, Chaohao Du, Xiao Liu, Shanshan Zhu, Wei Zhang, Zhigang Li, Chao Gao, Xiaoxi Zhao, Mei Mei, Shilai Bao, Huyong Zheng
Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF
Sanchita Roy, Edi Levi, Adhip PN Majumdar, Fazlul H Sarkar
Arsenic trioxide and ascorbic acid interfere with the BCL2 family genes in patients with myelodysplastic syndromes: an ex-vivo study
Sara Galimberti, Francesca Guerrini, Flavia Salvi, Iacopo Petrini, Daniela Gioia, Emanuela Messa, Giuseppe A Palumbo, Daniela Cilloni, Mario Petrini, Alessandro Levis
Homozygous A polymorphism of the complement C1qA 276 correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with R-CHOP
Xuan Jin, Huirong Ding, Ning Ding, Zhiying Fu, Yuqin Song, Jun Zhu
Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols
Wesley Greaves, Lianchun Xiao, Beatriz Sanchez-Espiridion, Kranthi Kunkalla, Kunal S Dave, Cynthia S Liang, Rajesh R Singh, Anas Younes, L Jeffrey Medeiros, Francisco Vega
SETBP1 and miR_4319 dysregulation in primary myelofibrosis progression to acute myeloid leukemia
Francesco Albano, Luisa Anelli, Antonella Zagaria, Nicoletta Coccaro, Paola Casieri, Angela Minervini, Giorgina Specchia
Serum VEGF levels as predictive marker of bisphosphonate-related osteonecrosis of the jaw
Bruno Vincenzi, Andrea Napolitano, Alice Zoccoli, Michele Iuliani, Francesco Pantano, Nicola Papapietro, Vincenzo Denaro, Daniele Santini, Giuseppe Tonini
HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas
Angela M Sosin, Angelika M Burger, Aisha Siddiqi, Judith Abrams, Ramzi M Mohammad, Ayad M Al-Katib
Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma
Kari Hemminki, Xiangdong Liu, Asta Försti, Jianguang Ji, Jan Sundquist, Kristina Sundquist
Overwhelming response to Dabrafenib in a patient with double BRAF mutation (V600E; V600M) metastatic malignant melanoma
Giovanni Ponti, Aldo Tomasi, Giovanni Pellacani
Arsenic trioxide improves hematopoiesis in refractory severe aplastic anemia
Ning Li, Yongping Song, Jian Zhou, Baijun Fang
The GATA1s isoform is normally down-regulated during terminal haematopoietic differentiation and over-expression leads to failure to repress MYB, CCND2 and SKI during erythroid differentiation of K562 cells
Christina Halsey, Marie Docherty, Mhairi McNeill, Derek Gilchrist, Michelle Le Brocq, Brenda Gibson, Gerard Graham
Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature
Carlos A Tirado, Weina Chen, Rolando García, Kelly A Kohlman, Nagesh Rao
Novel CD20 monoclonal antibodies for lymphoma therapy
Shundong Cang, Nikhil Mukhi, Kemeng Wang, Delong Liu
The unfolded von Willebrand factor response in bloodstream: the self-association perspective
Hailong Yuan, Ning Deng, Songmei Zhang, Yange Cao, Qiong Wang, Xin Liu, Qing Zhang
Bortezomib plus rituximab versus rituximab in patients with high-risk, relapsed, rituximab-naïve or rituximab-sensitive follicular lymphoma: subgroup analysis of a randomized phase 3 trial
Pier Luigi Zinzani, Nuriet K Khuageva, Huaqing Wang, Bernardo Garicochea, Jan Walewski, Achiel Van Hoof, Pierre Soubeyran, Dolores Caballero, Rena Buckstein, Dixie-Lee Esseltine, Panteli Theocharous, Christopher Enny, Eugene Zhu, Yusri A Elsayed, Bertrand Coiffier
Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization
Wen-Quan Wang, Liang Liu, Hui-Chuan Sun, Yan-Ling Fu, Hua-Xiang Xu, Zong-Tao Chai, Qiang-Bo Zhang, Ling-Qun Kong, Xiao-Dong Zhu, Lu Lu, Zheng-Gang Ren, Zhao-You Tang
Can EGFR-TKIs be used in first line treatment for advanced non-small cell lung cancer based on selection according to clinical factors ? -- A literature-based meta-analysis
Chongrui Xu, Qing Zhou, Yi-long Wu
Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy
Satyanarayana Rachagani, María P Torres, Sushil Kumar, Dhanya Haridas, Michael Baine, Muzafar A Macha, Sukhwinder Kaur, Moorthy P Ponnusamy, Parama Dey, Parthasarathy Seshacharyulu, Sonny L Johansson, Maneesh Jain, Kay-Uwe Wagner, Surinder K Batra
Targeted drug delivery for cancer therapy: the other side of antibodies
Michael A Firer, Gary Gellerman
SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells
Yao Guo, Yun Chen, Xuesong Xu, Xueqi Fu, Zhizhuang Joe Zhao
A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide
Eunice S Wang, Roger M Lyons, Richard A Larson, Sunil Gandhi, Delong Liu, Carmen Matei, Bart Scott, Kuolung Hu, Allen S Yang
MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling
Anthony Virtue, Hong Wang, Xiao-feng Yang
Angiogenesis in metastatic colorectal cancer and the benefits of targeted therapy
Weijing Sun
A novel monoclonal antibody of human stem cell factor inhibits umbilical cord blood stem cell ex vivo expansion
Jie Fan, Xinxin Ding, Yongping Jiang
Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia
Xianfeng Zha, Xiaojuan Yan, Qi Shen, Yuping Zhang, Xiuli Wu, Shaohua Chen, Bo Li, Lijian Yang, Suxia Geng, Jianyu Weng, Xin Du, Yangqiu Li
Recognizing and managing the expanded risk of tumor lysis syndrome in hematologic and solid malignancies
Ali McBride, Peter Westervelt