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Zeitschrift

Journal of Hematology & Oncology

Journal of Hematology & Oncology 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 142 Artikel )

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Anti-GD2/4-1BB chimeric antigen receptor T cell therapy for the treatment of Chinese melanoma patients

Jiayi Yu, Xiaowen Wu, Junya Yan, Huan Yu, Longwen Xu, Zhihong Chi, Xinan Sheng, Lu Si, Chuanliang Cui, Jie Dai, Meng Ma, Tianxiao Xu, Yan Kong, Jun Guo

01.12.2018 | Retraction Note | Ausgabe 1/2018 Open Access

Retraction Note to: Decreased expression of the long noncoding RNA LINC00261 indicate poor prognosis in gastric cancer and suppress gastric cancer metastasis by affecting the epithelial–mesenchymal transition

Yu Fan, Yan-fen Wang, Hua-fang Su, Na Fang, Chen Zou, Wen-feng Li, Zheng-hua Fei

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Precision therapy for acute myeloid leukemia

Xue Yang, Jianxiang Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia

Amy Y. Wang, Howard Weiner, Margaret Green, Hua Chang, Noreen Fulton, Richard A. Larson, Olatoyosi Odenike, Andrew S. Artz, Michael R. Bishop, Lucy A. Godley, Michael J. Thirman, Satyajit Kosuri, Jane E. Churpek, Emily Curran, Kristen Pettit, Wendy Stock, Hongtao Liu

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Early presence of anti-angiogenesis-related adverse events as a potential biomarker of antitumor efficacy in metastatic gastric cancer patients treated with apatinib: a cohort study

Xinyang Liu, Shukui Qin, Zhichao Wang, Jianming Xu, Jianping Xiong, Yuxian Bai, Zhehai Wang, Yan Yang, Guoping Sun, Liwei Wang, Leizhen Zheng, Nong Xu, Ying Cheng, Weijian Guo, Hao Yu, Tianshu Liu, Pagona Lagiou, Jin Li

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: MicroRNA-330-3p promotes cell invasion and metastasis in non-small cell lung cancer through GRIA3 by activating MAPK/ERK signaling pathway

Chun-Hua Wei, Gang Wu, Qian Cai, Xi-Can Gao, Fan Tong, Rui Zhou, Rui-Guang Zhang, Ji-Hua Dong, Yu Hu, Xiao-Rong Dong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia

Jinghua Wang, Siyu Chen, Wei Xiao, Wende Li, Liang Wang, Shuo Yang, Weida Wang, Liping Xu, Shuangye Liao, Wenjian Liu, Yang Wang, Nawei Liu, Jianeng Zhang, Xiaojun Xia, Tiebang Kang, Gong Chen, Xiuyu Cai, Han Yang, Xing Zhang, Yue Lu, Penghui Zhou

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Cancer immunotherapy beyond immune checkpoint inhibitors

Julian A. Marin-Acevedo, Aixa E. Soyano, Bhagirathbhai Dholaria, Keith L. Knutson, Yanyan Lou

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel

J. Caers, B. Paiva, E. Zamagni, X. Leleu, J. Bladé, S. Y. Kristinsson, C. Touzeau, N. Abildgaard, E. Terpos, R. Heusschen, E. Ocio, M. Delforge, O. Sezer, M. Beksac, H. Ludwig, G. Merlini, P. Moreau, S. Zweegman, M. Engelhardt, L. Rosiñol

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

Jiancheng Wang, Xin Liu, Yuan Qiu, Yue Shi, Jianye Cai, Boyan Wang, Xiaoyue Wei, Qiong Ke, Xin Sui, Yi Wang, Yinong Huang, Hongyu Li, Tao Wang, Ren Lin, Qifa Liu, Andy Peng Xiang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a

Man-Qing Cao, A-Bin You, Xiao-Dong Zhu, Wei Zhang, Yuan-Yuan Zhang, Shi-Zhe Zhang, Ke-wei Zhang, Hao Cai, Wen-Kai Shi, Xiao-Long Li, Kang-Shuai Li, Dong-Mei Gao, De-Ning Ma, Bo-Gen Ye, Cheng-Hao Wang, Cheng-Dong Qin, Hui-Chuan Sun, Ti Zhang, Zhao-You Tang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Current trials for frontline therapy of mantle cell lymphoma

Raphael E. Steiner, Jorge Romaguera, Michael Wang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Novel agents for pancreatic ductal adenocarcinoma: emerging therapeutics and future directions

Yiyin Zhang, Chao Yang, He Cheng, Zhiyao Fan, Qiuyi Huang, Yu Lu, Kun Fan, Guopei Luo, Kaizhou Jin, Zhengshi Wang, Chen Liu, Xianjun Yu

01.12.2018 | Rapid communication | Ausgabe 1/2018 Open Access

Activity of pembrolizumab in relapsed/refractory NK/T-cell lymphoma

Xin Li, Yasong Cheng, Mingzhi Zhang, Jiaqin Yan, Ling Li, Xiaorui Fu, Xudong Zhang, Yu Chang, Zhenchang Sun, Hui Yu, Lei Zhang, Xinhua Wang, Jingjing Wu, Zhaoming Li, Feifei Nan, Li Tian, Wencai Li, Ken H. Young

01.12.2018 | Research | Ausgabe 1/2018 Open Access

PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse

Bingxin Zheng, Tingting Ren, Yi Huang, Kunkun Sun, Shidong Wang, Xing Bao, Kuisheng Liu, Wei Guo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways

Su-Jie Ni, Li-Qin Zhao, Xiao-Feng Wang, Zhen-Hua Wu, Rui-Xi Hua, Chun-Hua Wan, Jie-Yun Zhang, Xiao-Wei Zhang, Ming-Zhu Huang, Lu Gan, Hua-Lin Sun, Goberdhan P. Dimri, Wei-Jian Guo

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Distinct genetic alteration profiles of acute myeloid leukemia between Caucasian and Eastern Asian population

Hui Wei, Ying Wang, Chunlin Zhou, Dong Lin, Bingcheng Liu, Kaiqi Liu, Shaowei Qiu, Benfa Gong, Yan Li, Guangji Zhang, Shuning Wei, Xiaoyuan Gong, Yuntao Liu, Xingli Zhao, Runxia Gu, Yingchang Mi, Jianxiang Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS

Yumin Huang, John Hale, Yaomei Wang, Wei Li, Shijie Zhang, Jieying Zhang, Huizhi Zhao, Xinhua Guo, Jing Liu, Hongxia Yan, Karina Yazdanbakhsh, Gang Huang, Christopher D. Hillyer, Narla Mohandas, Lixiang Chen, Ling Sun, Xiuli An

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer

Zuhua Chen, Wenwen Huang, Tiantian Tian, Wanchun Zang, Jingyuan Wang, Zhentao Liu, Zhongwu Li, Yumei Lai, Zhi Jiang, Jing Gao, Lin Shen

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Circular RNAs: a new frontier for cancer diagnosis and therapy

Miaoci Zhang, Yan Xin

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Chimeric antigen receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward

Jian Li, Wenwen Li, Kejia Huang, Yang Zhang, Gary Kupfer, Qi Zhao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Artesunate shows potent anti-tumor activity in B-cell lymphoma

Thea Kristin Våtsveen, Marit Renée Myhre, Chloé Beate Steen, Sébastien Wälchli, Ole Christian Lingjærde, Baoyan Bai, Pierre Dillard, Theodossis A. Theodossiou, Toril Holien, Anders Sundan, Else Marit Inderberg, Erlend B. Smeland, June Helen Myklebust, Morten P. Oksvold

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer

Alessandra Metelli, Mohammad Salem, Caroline H. Wallace, Bill X. Wu, Anqi Li, Xue Li, Zihai Li

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A novel generation 1928zT2 CAR T cells induce remission in extramedullary relapse of acute lymphoblastic leukemia

Jianyu Weng, Peilong Lai, Le Qin, Yunxin Lai, Zhiwu Jiang, Chenwei Luo, Xin Huang, Suijing Wu, Dan Shao, Chengxin Deng, Lisi Huang, Zesheng Lu, Maohua Zhou, Lingji Zeng, Dongmei Chen, Yulian Wang, Xiaomei Chen, Suxia Geng, Weinkove Robert, Zhaoyang Tang, Chang He, Peng Li, Xin Du

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer

Bowen Liu, Tianjiao Wang, Huawei Wang, Lu Zhang, Feifei Xu, Runping Fang, Leilei Li, Xiaoli Cai, Yue Wu, Weiying Zhang, Lihong Ye

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

Lulu Liu, Xiaoling Wan, Peipei Zhou, Xiaoyuan Zhou, Wei Zhang, Xinhui Hui, Xiujie Yuan, Xiaodan Ding, Ruihong Zhu, Guangxun Meng, Hui Xiao, Feng Ma, He Huang, Xianmin Song, Bin Zhou, Sidong Xiong, Yan Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells

Bo Hu, Guang-Yu Ding, Pei-Yao Fu, Xiao-Dong Zhu, Yuan Ji, Guo-Ming Shi, Ying-Hao Shen, Jia-Bin Cai, Zhen Yang, Jian Zhou, Jia Fan, Hui-Chuan Sun, Ming Kuang, Cheng Huang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma

Zhihong Zheng, Shengjun Fan, Jing Zheng, Wei Huang, Cristina Gasparetto, Nelson J. Chao, Jianda Hu, Yubin Kang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CAMKs support development of acute myeloid leukemia

Xunlei Kang, Changhao Cui, Chen Wang, Guojin Wu, Heyu Chen, Zhigang Lu, Xiaoli Chen, Li Wang, Jie Huang, Huimin Geng, Meng Zhao, Zhengshan Chen, Markus Müschen, Huan-You Wang, Cheng Cheng Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Lessons learned from the blockade of immune checkpoints in cancer immunotherapy

Xiaolei Li, Changshun Shao, Yufang Shi, Weidong Han

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

Claudio Festuccia, Andrea Mancini, Alessandro Colapietro, Giovanni Luca Gravina, Flora Vitale, Francesco Marampon, Simona Delle Monache, Simona Pompili, Loredana Cristiano, Antonella Vetuschi, Vincenzo Tombolini, Yi Chen, Thomas Mehrling

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China—recommendations from the Chinese Society of Hematology

Lanping Xu, Hu Chen, Jing Chen, Mingzhe Han, He Huang, Yongrong Lai, Daihong Liu, Qifa Liu, Ting Liu, Ming Jiang, Hanyun Ren, Yongping Song, Zimin Sun, Jianmin Wang, Depei Wu, Daobin Zhou, Ping Zou, Kaiyan Liu, Xiaojun Huang

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Standardizing haematopoietic cell transplants in China

Robert Peter Gale

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel

David Porter, Noelle Frey, Patricia A. Wood, Yanqiu Weng, Stephan A. Grupp

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

Jianbiao Zhou, Sabrina Hui-Min Toh, Zit-Liang Chan, Jessie Yiying Quah, Jing-Yuan Chooi, Tuan Zea Tan, Phyllis S. Y. Chong, Qi Zeng, Wee-Joo Chng

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse

Bingxin Zheng, Tingting Ren, Yi Huang, Kunkun Sun, Shidong Wang, Xing Bao, Kuisheng Liu, Wei Guo

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

C. Festuccia, A. Mancini, A. Colapietro, G. L. Gravina, F. Vitale, F. Marampon, S. Delle Monache, S. Pompili, L. Cristiano, A. Vetuschi, V. Tombolini, Y. Chen, T. Mehrling

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Next generation of immune checkpoint therapy in cancer: new developments and challenges

Julian A. Marin-Acevedo, Bhagirathbhai Dholaria, Aixa E. Soyano, Keith L. Knutson, Saranya Chumsri, Yanyan Lou

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Post-transplant cyclophosphamide for graft-versus-host disease prophylaxis in HLA matched sibling or matched unrelated donor transplant for patients with acute leukemia, on behalf of ALWP-EBMT

Annalisa Ruggeri, Myriam Labopin, Andrea Bacigalupo, Boris Afanasyev, Jan J. Cornelissen, Ahmet Elmaagacli, Maija Itälä-Remes, Didier Blaise, Ellen Meijer, Yener Koc, Noel Milpied, Harry C. Schouten, Nicolaus Kroeger, Mohamad Mohty, Arnon Nagler

01.12.2018 | Research highlight | Ausgabe 1/2018 Open Access

CD19 CAR-T cell therapy for relapsed/refractory acute lymphoblastic leukemia: factors affecting toxicities and long-term efficacies

Li-Na Zhang, Yongping Song, Delong Liu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long-term effects of ruxolitinib versus best available therapy on bone marrow fibrosis in patients with myelofibrosis

Hans Michael Kvasnicka, Jürgen Thiele, Carlos E. Bueso-Ramos, William Sun, Jorge Cortes, Hagop M. Kantarjian, Srdan Verstovsek

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma

Cunzhen Shi, Xiangqun Li, Xiaogan Wang, Ning Ding, Lingyan Ping, Yunfei Shi, Lan Mi, Yumei Lai, Yuqin Song, Jun Zhu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Accurate control of dual-receptor-engineered T cell activity through a bifunctional anti-angiogenic peptide

Erhao Zhang, Jieyi Gu, Jianpeng Xue, Chenyu Lin, Chen Liu, Mengwei Li, Jingchao Hao, Sarra Setrerrahmane, Xiaowei Chi, Weiyan Qi, Jialiang Hu, Hanmei Xu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner

Francesca Andriani, Maria Teresa Majorini, Miguel Mano, Elena Landoni, Rosalba Miceli, Federica Facchinetti, Mavis Mensah, Enrico Fontanella, Matteo Dugo, Mauro Giacca, Ugo Pastorino, Gabriella Sozzi, Domenico Delia, Luca Roz, Daniele Lecis

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway

Rosemarie Tremblay-LeMay, Nasrin Rastgoo, Hong Chang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Gut microbiome modulates efficacy of immune checkpoint inhibitors

Ming Yi, Shengnan Yu, Shuang Qin, Qian Liu, Hanxiao Xu, Weiheng Zhao, Qian Chu, Kongming Wu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Multiple functions of m6A RNA methylation in cancer

Yutian Pan, Pei Ma, Yu Liu, Wei Li, Yongqian Shu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Response and progression-free survival according to planned treatment duration in patients with relapsed multiple myeloma treated with carfilzomib, lenalidomide, and dexamethasone (KRd) versus lenalidomide and dexamethasone (Rd) in the phase III ASPIRE study

Meletios Dimopoulos, Michael Wang, Vladimir Maisnar, Jiri Minarik, William Bensinger, Maria-Victoria Mateos, Mihaela Obreja, Julie Blaedel, Philippe Moreau

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity

Tianxiao Yang, Yilin Wang, Wenjuan Dai, Xixi Zheng, Jing Wang, Shushu Song, Lan Fang, Jiangfan Zhou, Weicheng Wu, Jianxin Gu

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Role of protein kinases CK1α and CK2 in multiple myeloma: regulation of pivotal survival and stress-managing pathways

Sabrina Manni, Marilena Carrino, Francesco Piazza

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Expression levels of long non-coding RNAs are prognostic for AML outcome

Arvind Singh Mer, Johan Lindberg, Christer Nilsson, Daniel Klevebring, Mei Wang, Henrik Grönberg, Soren Lehmann, Mattias Rantalainen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis

Qian Liu, Anping Li, Shengnan Yu, Shuang Qin, Na Han, Richard G. Pestell, Xinwei Han, Kongming Wu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Exosomal miRNAs in hepatocellular carcinoma development and clinical responses

Shuangshuang Li, Jiping Yao, Mingjie Xie, Yanning Liu, Min Zheng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Unmanipulated haploidentical in comparison with matched unrelated donor stem cell transplantation in patients 60 years and older with acute myeloid leukemia: a comparative study on behalf of the ALWP of the EBMT

Nicole Santoro, Myriam Labopin, Federica Giannotti, Gerard Ehninger, Dietger Niederwieser, Arne Brecht, Matthias Stelljes, Nicolaus Kröger, Herman Einsele, Matthias Eder, Michael Hallek, Bertram Glass, Jürgen Finke, Fabio Ciceri, Mohamad Mohty, Annalisa Ruggeri, Arnon Nagler

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a

Man-Qing Cao, A-Bin You, Xiao-Dong Zhu, Wei Zhang, Yuan-Yuan Zhang, Shi-Zhe Zhang, Kei-wei Zhang, Hao Cai, Wen-Kai Shi, Xiao-Long Li, Kang-Shuai Li, Dong-Mei Gao, De-Ning Ma, Bo-Gen Ye, Cheng-Hao Wang, Cheng-Dong Qin, Hui-Chan Sun, Ti Zhang, Zhao-You Tang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Advances in CD30- and PD-1-targeted therapies for classical Hodgkin lymphoma

Yucai Wang, Grzegorz S. Nowakowski, Michael L. Wang, Stephen M. Ansell

01.12.2018 | Research | Ausgabe 1/2018 Open Access

miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy

Qian Huang, Jiajia Xia, Lei Wang, Xu Wang, Xiaodong Ma, Qipan Deng, Yong Lu, Munish Kumar, Zhiyuan Zhou, Ling Li, Zhaoyang Zeng, Ken H. Young, Qing Yi, Mingzhi Zhang, Yong Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery

Ting Li, Hu-Lin Jiang, Yun-Guang Tong, Jin-Jian Lu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Targeting FLT3 in acute myeloid leukemia using ligand-based chimeric antigen receptor-engineered T cells

Ying Wang, Yingxi Xu, Saisai Li, Jia Liu, Yanyan Xing, Haiyan Xing, Zheng Tian, Kejing Tang, Qing Rao, Min Wang, Jianxiang Wang

01.12.2018 | Case report | Ausgabe 1/2018 Open Access

First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases

Weili Sun, Huaying Liu, Young Kim, Nicole Karras, Anna Pawlowska, Debbie Toomey, Wade Kyono, Paul Gaynon, Joseph Rosenthal, Anthony Stein

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements

C. Roolf, A. Richter, C. Konkolefski, G. Knuebel, A. Sekora, S. Krohn, J. Stenzel, B. J. Krause, B. Vollmar, H. Murua Escobar, C. Junghanss

01.12.2018 | Review | Ausgabe 1/2018 Open Access

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

Nicola Amodio, Lavinia Raimondi, Giada Juli, Maria Angelica Stamato, Daniele Caracciolo, Pierosandro Tagliaferri, Pierfrancesco Tassone

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The biology and role of CD44 in cancer progression: therapeutic implications

Chen Chen, Shujie Zhao, Anand Karnad, James W. Freeman

01.12.2018 | Review | Ausgabe 1/2018 Open Access

BCL-2 as therapeutic target for hematological malignancies

Guilherme Fleury Perini, Glaciano Nogueira Ribeiro, Jorge Vaz Pinto Neto, Laura Tojeiro Campos, Nelson Hamerschlak

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC

Rachel E. Piddock, Christopher R. Marlein, Amina Abdul-Aziz, Manar S. Shafat, Martin J. Auger, Kristian M. Bowles, Stuart A. Rushworth

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential

Ingrid Spaan, Reinier A. Raymakers, Anja van de Stolpe, Victor Peperzak

01.12.2018 | Case report | Ausgabe 1/2018 Open Access

Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma

Carmela De Santo, Paul Cheng, Andrew Beggs, Sharon Egan, Alberto Bessudo, Francis Mussai

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Safety of pazopanib and sunitinib in treatment-naive patients with metastatic renal cell carcinoma: Asian versus non-Asian subgroup analysis of the COMPARZ trial

Jun Guo, Jie Jin, Mototsugu Oya, Hirotsugu Uemura, Shunji Takahashi, Katsunori Tatsugami, Sun Young Rha, Jae-Lyun Lee, Jinsoo Chung, Ho Yeong Lim, Hsi Chin Wu, Yen Hwa Chang, Arun Azad, Ian D. Davis, Marlene J. Carrasco-Alfonso, Bhupinder Nanua, Jackie Han, Qasim Ahmad, Robert Motzer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway

Hong Li, Lei Chen, Jun-jie Li, Qiang Zhou, Annie Huang, Wei-wen Liu, Ke Wang, Liang Gao, Song-tao Qi, Yun-tao Lu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Randomized, phase I/II study of gemcitabine plus IGF-1R antagonist (MK-0646) versus gemcitabine plus erlotinib with and without MK-0646 for advanced pancreatic adenocarcinoma

Reham Abdel-Wahab, Gauri R. Varadhachary, Priya R. Bhosale, Xuemei Wang, David R. Fogelman, Rachna T. Shroff, Michael J. Overman, Robert A. Wolff, Milind Javle

01.12.2018 | Research | Ausgabe 1/2018 Open Access

STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

Lufeng Zheng, Chenxi Xiang, Xiaoman Li, Qianqian Guo, Lanlan Gao, Haiwei Ni, Yufeng Xia, Tao Xi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways

Xiaolan Lian, Yu-Min Lin, Shingo Kozono, Megan K. Herbert, Xin Li, Xiaohong Yuan, Jiangrui Guo, Yafei Guo, Min Tang, Jia Lin, Yiping Huang, Bixin Wang, Chenxi Qiu, Cheng-Yu Tsai, Jane Xie, Ziang Jeff Gao, Yong Wu, Hekun Liu, Xiao Zhen Zhou, Kun Ping Lu, Yuanzhong Chen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

Nithila A. Joseph, Shiow-Her Chiou, Zoe Lung, Cheng-Lin Yang, Tze-Yi Lin, Hui-Wen Chang, H. Sunny Sun, Sachin Kumar Gupta, Laising Yen, Shulhn-Der Wang, Kuan-Chih Chow

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Treating hematological malignancies with drugs inhibiting ribosome biogenesis: when and why

Enrico Derenzini, Alessandra Rossi, Davide Treré

01.12.2018 | Research | Ausgabe 1/2018 Open Access

MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis

Sadakatsu Ikeda, Maria Schwaederle, Mandakini Mohindra, Denis L. Fontes Jardim, Razelle Kurzrock

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy

Changhong Liu, Yan Zhang, Xiaoling She, Li Fan, Peiyao Li, Jianbo Feng, Haijuan Fu, Qing Liu, Qiang Liu, Chunhua Zhao, Yingnan Sun, Minghua Wu

01.12.2018 | Research highlight | Ausgabe 1/2018 Open Access

Basket trial of TRK inhibitors demonstrates efficacy in TRK fusion-positive cancers

Yu Chen, Ping Chi

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Predictors of atrial fibrillation in ibrutinib-treated CLL patients: a prospective study

Gianluigi Reda, Bruno Fattizzo, Ramona Cassin, Veronica Mattiello, Tatiana Tonella, Diana Giannarelli, Ferdinando Massari, Agostino Cortelezzi

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Overcoming endocrine resistance in metastatic hormone receptor-positive breast cancer

Anishka D’Souza, Darcy Spicer, Janice Lu

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel

D. Porter, N. Frey, P. A. Wood, Y. Weng, S. A. Grupp

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

Shihua Wang, Meiqian Xu, Xiaoxia Li, Xiaodong Su, Xian Xiao, Armand Keating, Robert Chunhua Zhao

01.12.2018 | Review | Ausgabe 1/2018 Open Access

NF-κB signaling and its relevance to the treatment of mantle cell lymphoma

Swathi Balaji, Makhdum Ahmed, Elizabeth Lorence, Fangfang Yan, Krystle Nomie, Michael Wang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy

Federico Rossari, Filippo Minutolo, Enrico Orciuolo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib

Liwei Lang, Chloe Shay, Yuanping Xiong, Parth Thakkar, Ron Chemmalakuzhy, Xuli Wang, Yong Teng

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Targeting ERBB2 mutations in solid tumors: biological and clinical implications

Sophie Cousin, Emmanuel Khalifa, Amandine Crombe, Yech’an Laizet, Carlo Lucchesi, Maud Toulmonde, Sylvestre Le Moulec, Céline Auzanneau, Isabelle Soubeyran, Antoine Italiano

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Multi-center phase II trial of bortezomib and rituximab maintenance combination therapy in patients with mantle cell lymphoma after consolidative autologous stem cell transplantation

Robert W. Chen, Joycelynne M. Palmer, Sarah Tomassetti, Leslie L. Popplewell, Jessica Alluin, Pritsana Chomchan, Auayporn P. Nademanee, Tanya Siddiqi, Ni-Chun Tsai, Lu Chen, Fay Zuo, Rosemarie Abary, Ji-lian Cai, Alex F. Herrera, John J. Rossi, Steven T. Rosen, Stephen J. Forman, Larry W. Kwak, Leona A. Holmberg

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in cancer

Xinwei Huang, Hong Zhang, Xiaoran Guo, Zongxin Zhu, Haibo Cai, Xiangyang Kong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

Yang Li, Changqian Zeng, Jialei Hu, Yue Pan, Yujia Shan, Bing Liu, Li Jia

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy

Qian Huang, Jiajia Xi, Lei Wang, Xu Wang, Xiaodong Ma, Qipan Deng, Yong Lu, Munish Kumar, Zhiyuan Zhou, Ling Li, Zhaoyang Zeng, Ken H. Young, Qing Yi, Mingzhi Zhang, Yong Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

T cell senescence and CAR-T cell exhaustion in hematological malignancies

Dimitri Kasakovski, Ling Xu, Yangqiu Li

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells

Yali Han, Wei Xie, De-Gang Song, Daniel J. Powell Jr

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Memory T cells skew toward terminal differentiation in the CD8+ T cell population in patients with acute myeloid leukemia

Ling Xu, Danlin Yao, Jiaxiong Tan, Zifan He, Zhi Yu, Jie Chen, Gengxin Luo, Chunli Wang, Fenfang Zhou, Xianfeng Zha, Shaohua Chen, Yangqiu Li

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways

Xiaolan Lian, Yu-Min Lin, Shingo Kozono, Megan K. Herbert, Xin Li, Xiaohong Yuan, Jiangrui Guo, Yafei Guo, Min Tang, Jia Lin, Yiping Huang, Bixin Wang, Chenxi Qiu, Cheng-Yu Tsai, Jane Xie, Ziang Jeff Gao, Yong Wu, Hekun Liu, Xiao Zhen Zhou, Kun Ping Lu, Yuanzhong Chen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy

Tong Shen, Ling-Dong Cai, Yu-Hong Liu, Shi Li, Wen-Juan Gan, Xiu-Ming Li, Jing-Ru Wang, Peng-Da Guo, Qun Zhou, Xing-Xing Lu, Li-Na Sun, Jian-Ming Li

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia

E. Genescà, A. Lazarenkov, M. Morgades, G. Berbis, N. Ruíz-Xivillé, P. Gómez-Marzo, J. Ribera, J. Juncà, A. González-Pérez, S. Mercadal, R. Guardia, M. T. Artola, M. J. Moreno, J. Martínez-López, L. Zamora, P. Barba, C. Gil, M. Tormo, A. Cladera, A. Novo, M. Pratcorona, J. Nomdedeu, J. González-Campos, M. Almeida, J. Cervera, P. Montesinos, M. Batlle, S. Vives, J. Esteve, E. Feliu, F. Solé, A. Orfao, J. M. Ribera

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Immune cell subset differentiation and tissue inflammation

Pu Fang, Xinyuan Li, Jin Dai, Lauren Cole, Javier Andres Camacho, Yuling Zhang, Yong Ji, Jingfeng Wang, Xiao-Feng Yang, Hong Wang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Function and clinical significance of circRNAs in solid tumors

Yiting Geng, Jingting Jiang, Changping Wu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia

Andrea Ghelli Luserna Di Rorà, Neil Beeharry, Enrica Imbrogno, Anna Ferrari, Valentina Robustelli, Simona Righi, Elena Sabattini, Maria Vittoria Verga Falzacappa, Chiara Ronchini, Nicoletta Testoni, Carmen Baldazzi, Cristina Papayannidis, Maria Chiara Abbenante, Giovanni Marconi, Stefania Paolini, Sarah Parisi, Chiara Sartor, Maria Chiara Fontana, Serena De Matteis, Ilaria Iacobucci, Pier Giuseppe Pelicci, Michele Cavo, Timothy J. Yen, Giovanni Martinelli

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting the IDO1 pathway in cancer: from bench to bedside

Ming Liu, Xu Wang, Lei Wang, Xiaodong Ma, Zhaojian Gong, Shanshan Zhang, Yong Li

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Evaluation of an alternative ruxolitinib dosing regimen in patients with myelofibrosis: an open-label phase 2 study

Moshe Talpaz, Susan Erickson-Viitanen, Kevin Hou, Solomon Hamburg, Maria R. Baer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy

Erhao Zhang, Peiwei Yang, Jieyi Gu, Heming Wu, Xiaowei Chi, Chen Liu, Ying Wang, Jianpeng Xue, Weiyan Qi, Qingbo Sun, Shengnan Zhang, Jialiang Hu, Hanmei Xu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Successful treatment of secondary poor graft function post allogeneic hematopoietic stem cell transplantation with eltrombopag

Cen Tang, Feng Chen, Danqing Kong, Qinfen Ma, Haiping Dai, Jia Yin, Zheng Li, Jia Chen, Xiaming Zhu, Xinliang Mao, Depei Wu, Xiaowen Tang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Abscopal effect of radiotherapy combined with immune checkpoint inhibitors

Yang Liu, Yinping Dong, Li Kong, Fang Shi, Hui Zhu, Jinming Yu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL

Shuhua Cheng, Giorgio Inghirami, Shuo Cheng, Wayne Tam

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Emerging roles of long non-coding RNAs in tumor metabolism

Hui Sun, Zhaohui Huang, Weiqi Sheng, Mi-die Xu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The roles of metallothioneins in carcinogenesis

Manfei Si, Jinghe Lang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E. de Bock, Olga Gielen, Mardelle Atkins, Jiekun Yan, Georg Halder, Bassem A. Hassan, Jan Cools

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Mouse avatar models of esophageal squamous cell carcinoma proved the potential for EGFR-TKI afatinib and uncovered Src family kinases involved in acquired resistance

Zhentao Liu, Zuhua Chen, Jingyuan Wang, Mengqi Zhang, Zhongwu Li, Shubin Wang, Bin Dong, Cheng Zhang, Jing Gao, Lin Shen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine

Federica Giannotti, Myriam Labopin, Roni Shouval, Jaime Sanz, William Arcese, Emanuele Angelucci, Jorge Sierra, Josep-Maria Ribera Santasusana, Stella Santarone, Bruno Benedetto, Alessandro Rambaldi, Riccardo Saccardi, Didier Blaise, Michele Angelo Carella, Vanderson Rocha, Frederic Baron, Mohamad Mohty, Annalisa Ruggeri, Arnon Nagler

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Histone deacetylase 6 in cancer

Ting Li, Chao Zhang, Shafat Hassan, Xinyue Liu, Fengju Song, Kexin Chen, Wei Zhang, Jilong Yang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA

Simon Heine, Markus Kleih, Neus Giménez, Kathrin Böpple, German Ott, Dolors Colomer, Walter E. Aulitzky, Heiko van der Kuip, Elisabeth Silkenstedt

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

Meng Zhang, Weiwei Weng, Qiongyan Zhang, Yong Wu, Shujuan Ni, Cong Tan, Midie Xu, Hui Sun, Chenchen Liu, Ping Wei, Xiang Du

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Selective killing of circulating tumor cells prevents metastasis and extends survival

Yi Rang Kim, Jung Ki Yoo, Chang Wook Jeong, Jin Woo Choi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer

Zhuoyu Gu, Yixin Li, Xiaoya Yang, Meisheng Yu, Zhanru Chen, Chan Zhao, Lixin Chen, Liwei Wang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Organoid technology and applications in cancer research

Hanxiao Xu, Xiaodong Lyu, Ming Yi, Weiheng Zhao, Yongping Song, Kongming Wu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction

Yingxue Qi, Wenchun Chen, Xinyu Liang, Ke Xu, Xiangyu Gu, Fengying Wu, Xuemei Fan, Shengxiang Ren, Junling Liu, Jun Zhang, Renhao Li, Jianwen Liu, Xin Liang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Long non-coding RNAs in esophageal cancer: molecular mechanisms, functions, and potential applications

Min Su, Yuhang Xiao, Junliang Ma, Deliang Cao, Yong Zhou, Hui Wang, Qianjin Liao, Wenxiang Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells

Marcia Bellon, Ramona Moles, Hassiba Chaib-Mezrag, Joanna Pancewicz, Christophe Nicot

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Anlotinib: a novel multi-targeting tyrosine kinase inhibitor in clinical development

Guoshuang Shen, Fangchao Zheng, Dengfeng Ren, Feng Du, Qiuxia Dong, Ziyi Wang, Fuxing Zhao, Raees Ahmad, Jiuda Zhao

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Cytokine release syndrome: grading, modeling, and new therapy

Delong Liu, Juanjuan Zhao

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

A phase Ib study to assess the efficacy and safety of vismodegib in combination with ruxolitinib in patients with intermediate- or high-risk myelofibrosis

Stephen Couban, Giulia Benevolo, William Donnellan, Jennifer Cultrera, Steffen Koschmieder, Srdan Verstovsek, Gregory Hooper, Christian Hertig, Maneesh Tandon, Natalie Dimier, Vikram Malhi, Francesco Passamonti

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

Daniela N Petrusca, Denise Toscani, Feng-Ming Wang, Cheolkyu Park, Colin D Crean, Judith L Anderson, Silvia Marino, Khalid S Mohammad, Dan Zhou, Rebecca Silbermann, Quanhong Sun, Noriyoshi Kurihara, Deborah L Galson, Nicola Giuliani, G David Roodman

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609)

Xu Liang, Adrien Briaux, Véronique Becette, Camille Benoist, Anais Boulai, Walid Chemlali, Anne Schnitzler, Sylvain Baulande, Sofia Rivera, Marie-Ange Mouret-Reynier, Laurence Venat Bouvet, Thibaut De La Motte Rouge, Jérôme Lemonnier, Florence Lerebours, Céline Callens

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of platelets and platelet receptors in cancer metastasis

Martin Schlesinger

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Tim-3 expression and its role in hepatocellular carcinoma

Feifei Liu, Yanning Liu, Zhi Chen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall survival: on behalf of the ALWP of the EBMT and the MSKCC

Florent Malard, Myriam Labopin, Christina Cho, Didier Blaise, Esperanza B. Papadopoulos, Jakob Passweg, Richard O’Reilly, Edouard Forcade, Molly Maloy, Liisa Volin, Hugo Castro-Malaspina, Yosr Hicheri, Ann A. Jakubowski, Corentin Orvain, Sergio Giralt, Mohamad Mohty, Arnon Nagler, Miguel-Angel Perales

01.12.2018 | Case report | Ausgabe 1/2018 Open Access

Anti-BCMA CAR-T cells for treatment of plasma cell dyscrasia: case report on POEMS syndrome and multiple myeloma

Jinhuan Xu, Qiuxiang Wang, Hao Xu, Chaojiang Gu, Lijun Jiang, Jue Wang, Di Wang, Bin Xu, Xia Mao, Jin Wang, Zhiqiong Wang, Yi Xiao, Yicheng Zhang, Chunrui Li, Jianfeng Zhou

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Clinical utility of tumor genomic profiling in patients with high plasma circulating tumor DNA burden or metabolically active tumors

Cathy Zhou, Zilong Yuan, Weijie Ma, Lihong Qi, Angelique Mahavongtrakul, Ying Li, Hong Li, Jay Gong, Reggie R. Fan, Jin Li, Michael Molmen, Travis A. Clark, Dean Pavlick, Garrett M. Frampton, Brady Forcier, Elizabeth H. Moore, David K. Shelton, Matthew Cooke, Siraj M. Ali, Vincent A. Miller, Jeffrey P. Gregg, Philip J. Stephens, Tianhong Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Chimeric antigen receptor-modified T cell therapy in chronic lymphocytic leukemia

Yixin Zou, Wei Xu, Jianyong Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies

Nonthaphat Kent Wong, Chien-Ling Huang, Rashidul Islam, Shea Ping Yip

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Universal CARs, universal T cells, and universal CAR T cells

Juanjuan Zhao, Quande Lin, Yongping Song, Delong Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

FLT3 inhibitors in acute myeloid leukemia

Mei Wu, Chuntuan Li, Xiongpeng Zhu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Advances in multiple omics of natural-killer/T cell lymphoma

Jie Xiong, Wei-Li Zhao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A potent immunomodulatory role of exosomes derived from mesenchymal stromal cells in preventing cGVHD

Peilong Lai, Xiaomei Chen, Liyan Guo, Yulian Wang, Xialin Liu, Yan Liu, Tian Zhou, Tian Huang, Suxia Geng, Chengwei Luo, Xin Huang, Suijing Wu, Wei Ling, Xin Du, Chang He, Jianyu Weng

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Proton beam therapy for cancer in the era of precision medicine

Man Hu, Liyang Jiang, Xiangli Cui, Jianguang Zhang, Jinming Yu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

Benoît Tessoulin, Agnès Moreau-Aubry, Géraldine Descamps, Patricia Gomez-Bougie, Sophie Maïga, Alban Gaignard, David Chiron, Emmanuelle Ménoret, Steven Le Gouill, Philippe Moreau, Martine Amiot, Catherine Pellat-Deceunynck

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Decreasing mortality and hospitalizations with rising costs related to gastric cancer in the USA: an epidemiological perspective

Delong Liu, Dhruv Mehta, Supreet Kaur, Arun Kumar, Kaushal Parikh, Lavneet Chawla, Shanti Patel, Amirta Devi, Aparna Saha

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang, Tiancong He, Shuai Liu, Yingying Zheng, Libing Xiang, Xuan Pei, Ziliang Wang, Huijuan Yang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Treatment of localized extranodal NK/T cell lymphoma, nasal type: a systematic review

Seok Jin Kim, Sang Eun Yoon, Won Seog Kim

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma

Wan-Hong Zhao, Jie Liu, Bai-Yan Wang, Yin-Xia Chen, Xing-Mei Cao, Yun Yang, Yi-Lin Zhang, Fang-Xia Wang, Peng-Yu Zhang, Bo Lei, Liu-Fang Gu, Jian-Li Wang, Nan Yang, Ru Zhang, Hui Zhang, Ying Shen, Ju Bai, Yan Xu, Xu-Geng Wang, Rui-Li Zhang, Li-Li Wei, Zong-Fang Li, Zhen-Zhen Li, Yan Geng, Qian He, Qiu-Chuan Zhuang, Xiao-Hu Fan, Ai-Li He, Wang-Gang Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing

Zihai Li, Wenru Song, Mark Rubinstein, Delong Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Management of adverse events associated with bosutinib treatment of chronic-phase chronic myeloid leukemia: expert panel review

Jorge E. Cortes, Jane F. Apperley, Daniel J. DeAngelo, Michael W. Deininger, Vamsi K. Kota, Philippe Rousselot, Carlo Gambacorti-Passerini

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