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Zeitschrift

Journal of Hematology & Oncology

Journal of Hematology & Oncology 1/2020

Ausgabe 1/2020

Inhaltsverzeichnis ( 133 Artikel )

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer

Xingsheng Hu, Xin Zheng, Sheng Yang, Lin Wang, Xuezhi Hao, Xinge Cui, Lieming Ding, Li Mao, Pei Hu, Yuankai Shi

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression

Zhenyao Chen, Xin Chen, Binbin Lu, Yu Gu, Qinnan Chen, Tianyao Lei, Fengqi Nie, Jingyao Gu, Jiali Huang, Chenchen Wei, Ming Sun, Zhaoxia Wang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia

Ola A. Elgamal, Abeera Mehmood, Jae Yoon Jeon, Bridget Carmichael, Amy Lehman, Shelley J. Orwick, Jean Truxall, Virginia M. Goettl, Ronni Wasmuth, Minh Tran, Shaneice Mitchell, Rosa Lapalombella, Sudharshan Eathiraj, Brian Schwartz, Kimberly Stegmaier, Sharyn D. Baker, Erin Hertlein, John C. Byrd

01.12.2020 | Research | Ausgabe 1/2020 Open Access

MiR-509-3 augments the synthetic lethality of PARPi by regulating HR repair in PDX model of HGSOC

Chenggong Sun, Wenyu Cao, Chunping Qiu, Chengcheng Li, Samina Dongol, Zhiwei Zhang, Ruifen Dong, Kun Song, Xingsheng Yang, Qing Zhang, Beihua Kong

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Myeloid-derived suppressor cells—new and exciting players in lung cancer

Zhenzhen Yang, Jiacheng Guo, Lanling Weng, Wenxue Tang, Shuiling Jin, Wang Ma

01.12.2020 | Research | Ausgabe 1/2020 Open Access

CD73 sustained cancer-stem-cell traits by promoting SOX9 expression and stability in hepatocellular carcinoma

Xiao-Lu Ma, Bo Hu, Wei-Guo Tang, Su-Hong Xie, Ning Ren, Lin Guo, Ren-Quan Lu

01.12.2020 | Research | Ausgabe 1/2020 Open Access

MiR-612 regulates invadopodia of hepatocellular carcinoma by HADHA-mediated lipid reprogramming

Yang Liu, Li-Li Lu, Duo Wen, Dong-Li Liu, Li-Li Dong, Dong-Mei Gao, Xin-Yu Bian, Jian Zhou, Jia Fan, Wei-Zhong Wu

01.12.2020 | Short report | Ausgabe 1/2020 Open Access

Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers

F. Coussy, R. El Botty, M. Lavigne, C. Gu, L. Fuhrmann, A. Briaux, L. de Koning, A. Dahmani, E. Montaudon, L. Morisset, L. Huguet, L. Sourd, P. Painsec, S. Chateau-Joubert, T. Larcher, S. Vacher, S. Melaabi, A. Vincent Salomon, E. Marangoni, I. Bieche

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

NoncoRNA: a database of experimentally supported non-coding RNAs and drug targets in cancer

Lulu Li, Pengfei Wu, Zhenyu Wang, Xiangqi Meng, Caijun Zha, Ziwei Li, Tengfei Qi, Yangong Zhang, Bo Han, Shupeng Li, Chuanlu Jiang, Zheng Zhao, Jinquan Cai

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

Shaoquan Zheng, Lu Yang, Yutian Zou, Jie-ying Liang, Peng Liu, Guanfeng Gao, Anli Yang, Hailin Tang, Xiaoming Xie

01.12.2020 | Short report | Ausgabe 1/2020 Open Access

Haploidentical versus HLA-matched sibling transplantation for refractory acute leukemia undergoing sequential intensified conditioning followed by DLI: an analysis from two prospective data

Sijian Yu, Fen Huang, Zhiping Fan, Li Xuan, Danian Nie, Yajing Xu, Ting Yang, Shunqing Wang, Zujun Jiang, Na Xu, Ren Lin, Jieyu Ye, Dongjun Lin, Jing Sun, Xiaojun Huang, Yu Wang, Qifa Liu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Vasculogenic mimicry in carcinogenesis and clinical applications

Qingxi Luo, Jun Wang, Wenyuan Zhao, Zhenzi Peng, Xianyu Liu, Bin Li, Heng Zhang, Bin Shan, Chunfang Zhang, Chaojun Duan

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Treating non-responders: pitfalls and implications for cancer immunotherapy trial design

Zhenzhen Xu, Yongsoek Park, Ke Liu, Bin Zhu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Treatment of mantle cell lymphoma in Asia: a consensus paper from the Asian Lymphoma Study Group

Dok Hyun Yoon, Junning Cao, Tsai-Yun Chen, Koji Izutsu, Seok Jin Kim, Yok Lam Kwong, Tong Yu Lin, Lim Soon Thye, Bing Xu, Deok Hwan Yang, Won Seog Kim

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Identification of cross-talk between m6A and 5mC regulators associated with onco-immunogenic features and prognosis across 33 cancer types

Yu-Tong Chen, Jia-Yi Shen, Dong-Ping Chen, Chen-Fei Wu, Rui Guo, Pan-Pan Zhang, Jia-Wei Lv, Wen-Fei Li, Zi-Xian Wang, Yu-Pei Chen

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

Shaoquan Zheng, Lu Yang, Yutian Zou, Jie-ying Liang, Peng Liu, Guanfeng Gao, Anli Yang, Hailin Tang, Xiaoming Xie

01.12.2020 | Research | Ausgabe 1/2020 Open Access

HNF4A-AS1/hnRNPU/CTCF axis as a therapeutic target for aerobic glycolysis and neuroblastoma progression

Huajie Song, Dan Li, Xiaojing Wang, Erhu Fang, Feng Yang, Anpei Hu, Jianqun Wang, Yanhua Guo, Yang Liu, Hongjun Li, Yajun Chen, Kai Huang, Liduan Zheng, Qiangsong Tong

01.12.2020 | Review | Ausgabe 1/2020 Open Access

The role of cancer-derived microRNAs in cancer immune escape

Ming Yi, Linping Xu, Ying Jiao, Suxia Luo, Anping Li, Kongming Wu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

The design and development of covalent protein-protein interaction inhibitors for cancer treatment

Sha-Sha Cheng, Guan-Jun Yang, Wanhe Wang, Chung-Hang Leung, Dik-Lung Ma

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Haploidentical donor is preferred over matched sibling donor for pre-transplantation MRD positive ALL: a phase 3 genetically randomized study

Ying-Jun Chang, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei-Han, Yu-Qian Sun, Chen-Hua Yan, Fei-Fei Tang, Xiao-Dong Mo, Yan-Rong Liu, Kai-Yan Liu, Xiao-Jun Huang

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Expression patterns of immune checkpoints in acute myeloid leukemia

Cunte Chen, Chaofeng Liang, Shunqing Wang, Chi Leong Chio, Yuping Zhang, Chengwu Zeng, Shaohua Chen, Caixia Wang, Yangqiu Li

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy

Chongxian Pan, Hongtao Liu, Elizabeth Robins, Wenru Song, Delong Liu, Zihai Li, Lei Zheng

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

Hanren Dai, Zhiqiang Wu, Hejin Jia, Chuan Tong, Yelei Guo, Dongdong Ti, Xiao Han, Yang Liu, Wenying Zhang, Chunmeng Wang, Yajing Zhang, Meixia Chen, Qingming Yang, Yao Wang, Weidong Han

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Mechanisms and rejuvenation strategies for aged hematopoietic stem cells

Xia Li, Xiangjun Zeng, Yulin Xu, Binsheng Wang, Yanmin Zhao, Xiaoyu Lai, Pengxu Qian, He Huang

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

Juan Manuel Domínguez, Gema Pérez-Chacón, María José Guillén, María José Muñoz-Alonso, Beatriz Somovilla-Crespo, Danay Cibrián, Bárbara Acosta-Iborra, Magdalena Adrados, Cecilia Muñoz-Calleja, Carmen Cuevas, Francisco Sánchez-Madrid, Pablo Avilés, Juan M. Zapata

01.12.2020 | Editorial | Ausgabe 1/2020 Open Access

Targeting epigenetics in sarcomas through EZH2 inhibition

Antoine Italiano

01.12.2020 | Research | Ausgabe 1/2020 Open Access

CRISPR/CAS9-mediated knockout of Abi1 inhibits p185Bcr-Abl-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

James Faulkner, Peixin Jiang, Delaney Farris, Ryan Walker, Zonghan Dai

01.12.2020 | Review | Ausgabe 1/2020 Open Access

m6A-binding proteins: the emerging crucial performers in epigenetics

Yanchun Zhao, Yuanfei Shi, Huafei Shen, Wanzhuo Xie

01.12.2020 | Research | Ausgabe 1/2020 Open Access

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

Victor Pallarès, Ugutz Unzueta, Aïda Falgàs, Laura Sánchez-García, Naroa Serna, Alberto Gallardo, Gordon A. Morris, Lorena Alba-Castellón, Patricia Álamo, Jorge Sierra, Antonio Villaverde, Esther Vázquez, Isolda Casanova, Ramon Mangues

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Association of genetic and immuno-characteristics with clinical outcomes in patients with RET-rearranged non-small cell lung cancer: a retrospective multicenter study

Chang Lu, Xiao-Rong Dong, Jun Zhao, Xu-Chao Zhang, Hua-Jun Chen, Qing Zhou, Hai-Yan Tu, Xing-Hao Ai, Xiao-Feng Chen, Gai-Li An, Jun Bai, Jin-Lu Shan, Yi-Na Wang, Shuan-Ying Yang, Xiang Liu, Wu Zhuang, Hui-Ta Wu, Bo Zhu, Xue-Feng Xia, Rong-Rong Chen, De-Jian Gu, Hua-Min Xu, Yi-Long Wu, Jin-Ji Yang

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

A phase 3 study of rituximab biosimilar HLX01 in patients with diffuse large B-cell lymphoma

Yuankai Shi, Yongping Song, Yan Qin, Qingyuan Zhang, Xiaohong Han, Xiaonan Hong, Dong Wang, Wei Li, Yang Zhang, Jifeng Feng, Jianmin Yang, Huilai Zhang, Chuan Jin, Yu Yang, Jianda Hu, Zhao Wang, Zhengming Jin, Hang Su, Huaqing Wang, Haiyan Yang, Weijun Fu, Mingzhi Zhang, Xiaohong Zhang, Yun Chen, Xiaoyan Ke, Li Liu, Ding Yu, Guo’an Chen, Xiuli Wang, Jie Jin, Tao Sun, Xin Du, Ying Cheng, Pingyong Yi, Xielan Zhao, Chaoming Ma, Jiancheng Cheng, Katherine Chai, Alvin Luk, Eugene Liu, Xin Zhang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Participation of the ATR/CHK1 pathway in replicative stress targeted therapy of high-grade ovarian cancer

Patrycja Gralewska, Arkadiusz Gajek, Agnieszka Marczak, Aneta Rogalska

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation

Xinfang Yu, Wei Li, Haidan Liu, Qipan Deng, Xu Wang, Hui Hu, Zijun Y. Xu-Monette, Wei Xiong, Zhongxin Lu, Ken H. Young, Wei Wang, Yong Li

01.12.2020 | Review | Ausgabe 1/2020 Open Access

The application and prospect of CDK4/6 inhibitors in malignant solid tumors

Qi Du, Xiang Guo, Miao Wang, Yongfu Li, Xiaoyi Sun, Qin Li

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

Pre-transplant MRD negativity predicts favorable outcomes of CAR-T therapy followed by haploidentical HSCT for relapsed/refractory acute lymphoblastic leukemia: a multi-center retrospective study

Houli Zhao, Jieping Wei, Guoqing Wei, Yi Luo, Jimin Shi, Qu Cui, Mingfeng Zhao, Aibin Liang, Qing Zhang, Jianmin Yang, Xin Li, Jing Chen, Xianmin Song, Hongmei Jing, Yuhua Li, Siguo Hao, Wenjun Wu, Yamin Tan, Jian Yu, Yanmin Zhao, Xiaoyu Lai, Elaine Tan Su Yin, Yunxiong Wei, Ping Li, Jing Huang, Tao Wang, Didier Blaise, Lei Xiao, Alex H. Chang, Arnon Nagler, Mohamad Mohty, He Huang, Yongxian Hu

05.05.2020 | COVID-19 | Letter to the Editor | Ausgabe 1/2020 Open Access

Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis

Peiwei Chai, Jie Yu, Shengfang Ge, Renbing Jia, Xianqun Fan

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: MiR-612 regulates invadopodia of hepatocellular carcinoma by HADHA-mediated lipid reprogramming

Yang Liu, Li-Li Lu, Duo Wen, Dong-Li Liu, Li-Li Dong, Dong-Mei Gao, Xin-Yu Bian, Jian Zhou, Jia Fan, Wei-Zhong Wu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

How to select IgG subclasses in developing anti-tumor therapeutic antibodies

Jifeng Yu, Yongping Song, Wenzhi Tian

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT

Jaime Sanz, Jacques-Emmanuel Galimard, Myriam Labopin, Boris Afanasyev, Emanuele Angelucci, Fabio Ciceri, Didier Blaise, Jan J. Cornelissen, Ellen Meijer, J. L. Diez-Martin, Yener Koc, Montserrat Rovira, Luca Castagna, Bipin Savani, Annalisa Ruggeri, Arnon Nagler, Mohamad Mohty, Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Reactive cutaneous capillary endothelial proliferation in advanced hepatocellular carcinoma patients treated with camrelizumab: data derived from a multicenter phase 2 trial

Feng Wang, Shukui Qin, Xinchen Sun, Zhenggang Ren, Zhiqiang Meng, Zhendong Chen, Xiaoli Chai, Jianping Xiong, Yuxian Bai, Lin Yang, Hong Zhu, Weijia Fang, Xiaoyan Lin, Xiaoming Chen, Enxiao Li, Linna Wang, Ping Yan, Jianjun Zou

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Treatment of relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma with the BTK inhibitor zanubrutinib: phase 2, single-arm, multicenter study

Wei Xu, Shenmiao Yang, Keshu Zhou, Ling Pan, Zengjun Li, Jianfeng Zhou, Sujun Gao, Daobin Zhou, Jianda Hu, Ru Feng, Haiwen Huang, Meng Ji, Haiyi Guo, Jane Huang, William Novotny, Shibao Feng, Jianyong Li

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Relative survival in early-stage cancers in the Netherlands: a population-based study

Avinash G. Dinmohamed, Valery E. P. P. Lemmens, Ignace H. J. T. de Hingh, Otto Visser

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy

Xin Li, Yongcheng Song

01.12.2020 | Editorial | Ausgabe 1/2020 Open Access

Anticancer drug R&D landscape in China

Shen Zhao, Hongyun Zhao, Cheng Lv, Jifang Gong, Jian Zhang, Wenfeng Fang, Jin Li, Xichun Hu, Yi Ba, Binghe Xu, Yanqiao Zhang, Yun Fan, Kunyan Li, Xiaoyuan Chen, Zhimin Yang, Lin Shen, Li Zhang

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Comparison of haplo-SCT and chemotherapy for young adults with standard-risk Ph-negative acute lymphoblastic leukemia in CR1

Meng Lv, Qian Jiang, Dao-Bin Zhou, Yu Hu, Dai-Hong Liu, De-Pei Wu, Jing-Bo Wang, Hao Jiang, Jing Wang, Ying-jun Chang, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

Hanren Dai, Zhiqiang Wu, Hejin Jia, Chuan Tong, Yelei Guo, Dongdong Ti, Xiao Han, Yang Liu, Wenying Zhang, Chunmeng Wang, Yajing Zhang, Meixia Chen, Qingming Yang, Yao Wang, Weidong Han

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Gene modification strategies for next-generation CAR T cells against solid cancers

Yonggui Tian, Yilu Li, Yupei Shao, Yi Zhang

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

PD1/PD-L1 targeting in advanced soft-tissue sarcomas: a pooled analysis of phase II trials

Antoine Italiano, Carine Bellera, Sandra D’Angelo

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Allogeneic stem cell transplantation for peripheral T cell lymphomas: a retrospective study in 285 patients from the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC)

Anne-Claire Mamez, Axelle Dupont, Didier Blaise, Patrice Chevallier, Edouard Forcade, Patrice Ceballos, Mohamad Mohty, Felipe Suarez, Yves Beguin, Regis Peffault De Latour, Marie-Thérèse Rubio, Olivier Tournilhac, Stéphanie Nguyen

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer

Qiang Wang, Wei Geng, Huimin Guo, Zhangding Wang, Kaiyue Xu, Chen Chen, Shouyu Wang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Emerging therapeutic agents for advanced non-small cell lung cancer

Ruqin Chen, Rami Manochakian, Lauren James, Abdel-Ghani Azzouqa, Huashan Shi, Yan Zhang, Yujie Zhao, Kexun Zhou, Yanyan Lou

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Biomarker-driven management strategies for peripheral T cell lymphoma

Erin Mulvey, Jia Ruan

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Emerging agents that target signaling pathways in cancer stem cells

Yue Yang, Xiaoman Li, Ting Wang, Qianqian Guo, Tao Xi, Lufeng Zheng

01.12.2020 | Review | Ausgabe 1/2020 Open Access

XPO1-dependent nuclear export as a target for cancer therapy

Nancy G. Azizian, Yulin Li

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer

Chia-Sing Lu, Ai-Li Shiau, Bing-Hua Su, Tsui-Shan Hsu, Chung-Teng Wang, Yu-Chu Su, Ming-Shian Tsai, Yin-Hsun Feng, Yau-Lin Tseng, Yi-Ting Yen, Chao-Liang Wu, Gia-Shing Shieh

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Discovery of proangiogenic CD44+mesenchymal cancer stem cells in an acute myeloid leukemia patient’s bone marrow

Huynh Cao, Jeffrey Xiao, Mark E. Reeves, Kimberly Payne, Chien Shing Chen, David J. Baylink, Guido Marcucci, Yi Xu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

Hui Hua, Qingbin Kong, Jie Yin, Jin Zhang, Yangfu Jiang

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Antibody-drug conjugates in clinical trials for lymphoid malignancies and multiple myeloma

Bo Yu, Delong Liu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Ibrutinib dose modifications in the management of CLL

Camille Hardy-Abeloos, Rachel Pinotti, Janice Gabrilove

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Non-coding RNAs shuttled via exosomes reshape the hypoxic tumor microenvironment

Wenyu Wang, Youngjin Han, Hyun A Jo, Juwon Lee, Yong Sang Song

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients

Dan Wang, Weina Yu, Jingyao Lian, Qian Wu, Shasha Liu, Li Yang, Feng Li, Lan Huang, Xinfeng Chen, Zhen Zhang, Aitian Li, Jinbo Liu, Zhenqiang Sun, Junxia Wang, Weitang Yuan, Yi Zhang

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

IMpower, CASPIAN, and more: exploring the optimal first-line immunotherapy for extensive-stage small cell lung cancer

Chengliang Huang, Gregory N. Gan, Jun Zhang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Evolving therapy of adult acute lymphoblastic leukemia: state-of-the-art treatment and future directions

Bachar Samra, Elias Jabbour, Farhad Ravandi, Hagop Kantarjian, Nicholas J. Short

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

A randomized, open-label, Phase III study of obinutuzumab or rituximab plus CHOP in patients with previously untreated diffuse large B-Cell lymphoma: final analysis of GOYA

Laurie H. Sehn, Maurizio Martelli, Marek Trněný, Wenxin Liu, Christopher R. Bolen, Andrea Knapp, Deniz Sahin, Gila Sellam, Umberto Vitolo

01.12.2020 | Research | Ausgabe 1/2020 Open Access

The global burden and attributable risk factor analysis of acute myeloid leukemia in 195 countries and territories from 1990 to 2017: estimates based on the global burden of disease study 2017

Ming Yi, Anping Li, Linghui Zhou, Qian Chu, Yongping Song, Kongming Wu

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

PTENP1 is a ceRNA for PTEN: it’s CRISPR clear

Marianna Vitiello, Monica Evangelista, Yang Zhang, Leonardo Salmena, Pier Paolo Pandolfi, Laura Poliseno

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy

Fahmin Basher, Payal Dhar, Xin Wang, Derek A. Wainwright, Bin Zhang, Jeffrey Sosman, Zhe Ji, Jennifer D. Wu

12.06.2020 | COVID-19 | Research | Ausgabe 1/2020 Open Access

Cancer history is an independent risk factor for mortality in hospitalized COVID-19 patients: a propensity score-matched analysis

Yifan Meng, Wanrong Lu, Ensong Guo, Jia Liu, Bin Yang, Ping Wu, Shitong Lin, Ting Peng, Yu Fu, Fuxia Li, Zizhuo Wang, Yuan Li, Rourou Xiao, Chen Liu, Yuhan Huang, Funian Lu, Xue Wu, Lixin You, Ding Ma, Chaoyang Sun, Peng Wu, Gang Chen

01.12.2020 | Review | Ausgabe 1/2020 Open Access

CD155 immunoregulation as a target for natural killer cell immunotherapy in glioblastoma

Kyle B. Lupo, Sandro Matosevic

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma

Xiangxiang Zhou, Na Chen, Hongzhi Xu, Xiaoming Zhou, Jianhong Wang, Xiaosheng Fang, Ya Zhang, Ying Li, Juan Yang, Xin Wang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

Wen-Tao Wang, Tian-Qi Chen, Zhan-Cheng Zeng, Qi Pan, Wei Huang, Cai Han, Ke Fang, Lin-Yu Sun, Qian-Qian Yang, Dan Wang, Xue-Qun Luo, Yu-Meng Sun, Yue-Qin Chen

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Emerging therapies in mantle cell lymphoma

Walter Hanel, Narendranath Epperla

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition

Xinhua Xiao, Ping Liu, Donghe Li, Zhizhou Xia, Peihong Wang, Xiuli Zhang, Mingzhu Liu, Lujian Liao, Bo Jiao, Ruibao Ren

01.12.2020 | Review | Ausgabe 1/2020 Open Access

cGAS-STING, an important pathway in cancer immunotherapy

Minlin Jiang, Peixin Chen, Lei Wang, Wei Li, Bin Chen, Yu Liu, Hao Wang, Sha Zhao, Lingyun Ye, Yayi He, Caicun Zhou

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Measurable residual disease in multiple myeloma: ready for clinical practice?

Leire Burgos, Noemi Puig, Maria-Teresa Cedena, María-Victoria Mateos, Juan José Lahuerta, Bruno Paiva, Jesús F. San-Miguel

01.12.2020 | Review | Ausgabe 1/2020 Open Access

VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy

Xing Huang, Xiaozhen Zhang, Enliang Li, Gang Zhang, Xun Wang, Tianyu Tang, Xueli Bai, Tingbo Liang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Oncolytic viruses for cancer immunotherapy

Otto Hemminki, João Manuel dos Santos, Akseli Hemminki

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Autoantibody signature in hepatocellular carcinoma using seromics

Shu Zhang, Yuming Liu, Jing Chen, Hong Shu, Siyun Shen, Yin Li, Xinyuan Lu, Xinyi Cao, Liangqing Dong, Jieyi Shi, Ya Cao, Xiaoying Wang, Jian Zhou, Yinkun Liu, Lei Chen, Jia Fan, Guangyu Ding, Qiang Gao

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Recent advances in CAR-T cell engineering

Ruihao Huang, Xiaoping Li, Yundi He, Wen Zhu, Lei Gao, Yao Liu, Li Gao, Qin Wen, Jiang F. Zhong, Cheng Zhang, Xi Zhang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Post-transplant cyclophosphamide versus antithymocyte globulin in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from 10/10 HLA-matched unrelated donors

Eolia Brissot, Myriam Labopin, Ian Moiseev, J. J. Cornelissen, Ellen Meijer, Gwendolyn Van Gorkom, Montserrat Rovira, Fabio Ciceri, Laimonas Griskevicius, Didier Blaise, Edouard Forcade, Martin Mistrik, Stephan Mielke, Claude Eric Bulabois, Riitta Niittyvuopio, Eric Deconinck, Annalisa Ruggeri, Jaime Sanz, Alexandros Spyridonidis, Bipin Savani, Sebastian Giebel, Arnon Nagler, Mohamad Mohty

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Constructing an automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning

Yanguo Kong, Xiangyi Kong, Cheng He, Changsong Liu, Liting Wang, Lijuan Su, Jun Gao, Qi Guo, Ran Cheng

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy

Valentina Marchica, Valentina Franceschi, Rosanna Vescovini, Paola Storti, Emanuela Vicario, Denise Toscani, Alessia Zorzoli, Irma Airoldi, Benedetta Dalla Palma, Nicoletta Campanini, Eugenia Martella, Cristina Mancini, Federica Costa, Gaetano Donofrio, Nicola Giuliani

01.12.2020 | Review | Ausgabe 1/2020 Open Access

RNA-binding proteins in tumor progression

Hai Qin, Haiwei Ni, Yichen Liu, Yaqin Yuan, Tao Xi, Xiaoman Li, Lufeng Zheng

01.12.2020 | Review | Ausgabe 1/2020 Open Access

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignancies

Shunling Yuan, Zhaoping Liu, Zhenru Xu, Jing Liu, Ji Zhang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy

Jorge E. Cortes, Florian H. Heidel, Walter Fiedler, B. Douglas Smith, Tadeusz Robak, Pau Montesinos, Anna Candoni, Brian Leber, Mikkael A. Sekeres, Daniel A. Pollyea, Roxanne Ferdinand, Weidong Wendy Ma, Thomas O’Brien, Ashleigh O’Connell, Geoffrey Chan, Michael Heuser

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Beyond thrombosis: the impact of tissue factor signaling in cancer

Dusten Unruh, Craig Horbinski

15.07.2020 | COVID-19 | Research | Ausgabe 1/2020 Open Access

A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward

Bo Wang, Oliver Van Oekelen, Tarek H. Mouhieddine, Diane Marie Del Valle, Joshua Richter, Hearn Jay Cho, Shambavi Richard, Ajai Chari, Sacha Gnjatic, Miriam Merad, Sundar Jagannath, Samir Parekh, Deepu Madduri

01.12.2020 | Research | Ausgabe 1/2020 Open Access

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Yonghan He, Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Sajid Khan, Dinesh Thummuri, Yuma T. Ortiz, Xin Zhang, Dongwen Lv, Janet S. Wiegand, Wen Li, Adam C. Palmer, Guangrong Zheng, David M. Weinstock, Daohong Zhou

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Role of CD47 in Hematological Malignancies

Entsar Eladl, Rosemarie Tremblay-LeMay, Nasrin Rastgoo, Rumina Musani, Wenming Chen, Aijun Liu, Hong Chang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Modeling neoplastic disease with spheroids and organoids

Michele Zanoni, Michela Cortesi, Alice Zamagni, Chiara Arienti, Sara Pignatta, Anna Tesei

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Epidemiological trends of tracheal, bronchus, and lung cancer at the global, regional, and national levels: a population-based study

Yujiao Deng, Peng Zhao, Linghui Zhou, Dong Xiang, Jingjing Hu, Yu Liu, Jian Ruan, Xianghua Ye, Yi Zheng, Jia Yao, Zhen Zhai, Shuqian Wang, Si Yang, Ying Wu, Na Li, Peng Xu, Dai Zhang, Huafeng Kang, Jun Lyu, Zhijun Dai

01.12.2020 | Research | Ausgabe 1/2020 Open Access

CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancer

Jian Wang, Ruiguang Zhang, Zhenyu Lin, Sheng Zhang, Yaobing Chen, Jing Tang, Jiaxin Hong, Xiaoshu Zhou, Yan Zong, Yingzhuo Xu, Rui Meng, Shuangbing Xu, Li Liu, Tao Zhang, Kunyu Yang, Xiaorong Dong, Gang Wu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Crosstalks between inflammasome and autophagy in cancer

Chaeuk Chung, Wonhyoung Seo, Prashanta Silwal, Eun-Kyeong Jo

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia

Yan Jia, Wei Liu, Hui-En Zhan, Xiao-Ping Yi, Hui Liang, Qi-Li Zheng, Xin-Ya Jiang, Hai-Yan Zhou, Liang Zhao, Xie-Lan Zhao, Hui Zeng

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: The design and development of covalent protein-protein interaction inhibitors for cancer treatment

Sha-Sha Cheng, Guan-Jun Yang, Wanhe Wang, Chung-Hang Leung, Dik-Lung Ma

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

Yonghan He, Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu, Yaxia Yuan, Robert Hromas, Mingjiang Xu, Guangrong Zheng, Daohong Zhou

01.12.2020 | Review | Ausgabe 1/2020 Open Access

EZH2: a novel target for cancer treatment

Ran Duan, Wenfang Du, Weijian Guo

01.12.2020 | Review | Ausgabe 1/2020 Open Access

SBRT combined with PD-1/PD-L1 inhibitors in NSCLC treatment: a focus on the mechanisms, advances, and future challenges

Yu Chen, Min Gao, Zhaoqin Huang, Jinming Yu, Xiangjiao Meng

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis

Dan Jin, Jiwei Guo, Yan Wu, Jing Du, Lijuan Yang, Xiaohong Wang, Weihua Di, Baoguang Hu, Jiajia An, Lingqun Kong, Lei Pan, Guoming Su

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Dendritic cell biology and its role in tumor immunotherapy

Yingying Wang, Ying Xiang, Victoria W. Xin, Xian-Wang Wang, Xiao-Chun Peng, Xiao-Qin Liu, Dong Wang, Na Li, Jun-Ting Cheng, Yan-Ning Lyv, Shu-Zhong Cui, Zhaowu Ma, Qing Zhang, Hong-Wu Xin

01.12.2020 | Research | Ausgabe 1/2020 Open Access

The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma

Samrat Roy Choudhury, Cody Ashby, Ruslana Tytarenko, Michael Bauer, Yan Wang, Shayu Deshpande, Judith Den, Carolina Schinke, Maurizio Zangari, Sharmilan Thanendrarajan, Faith E. Davies, Frits van Rhee, Gareth J. Morgan, Brian A. Walker

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application

Yu-Meng Sun, Yue-Qin Chen

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Si Shi

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Targeting immune checkpoints in hematological malignancies

Basit Salik, Mark J. Smyth, Kyohei Nakamura

01.12.2020 | Research | Ausgabe 1/2020 Open Access

ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through direct and p53-mediated downregulation of p21

Irene Cosi, Annamaria Pellecchia, Emanuele De Lorenzo, Eugenio Torre, Michela Sica, Gabriella Nesi, Rosario Notaro, Maria De Angioletti

01.12.2020 | Review | Ausgabe 1/2020 Open Access

The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy

Jimin Yuan, Xiaoduo Dong, Jiajun Yap, Jiancheng Hu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Targeting EphA2 in cancer

Ta Xiao, Yuhang Xiao, Wenxiang Wang, Yan Yan Tang, Zhiqiang Xiao, Min Su

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Daratumumab, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma: subgroup analysis of CASTOR based on cytogenetic risk

Katja Weisel, Andrew Spencer, Suzanne Lentzsch, Hervé Avet-Loiseau, Tomer M. Mark, Ivan Spicka, Tamas Masszi, Birgitta Lauri, Mark-David Levin, Alberto Bosi, Vania Hungria, Michele Cavo, Je-Jung Lee, Ajay Nooka, Hang Quach, Markus Munder, Cindy Lee, Wolney Barreto, Paolo Corradini, Chang-Ki Min, Asher A. Chanan-Khan, Noemi Horvath, Marcelo Capra, Meral Beksac, Roberto Ovilla, Jae-Cheol Jo, Ho-Jin Shin, Pieter Sonneveld, Tineke Casneuf, Nikki DeAngelis, Himal Amin, Jon Ukropec, Rachel Kobos, Maria-Victoria Mateos

01.12.2020 | Editorial | Ausgabe 1/2020 Open Access

HMGB1 in inflammation and cancer

Shumin Wang, Yi Zhang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Roles of METTL3 in cancer: mechanisms and therapeutic targeting

Chengwu Zeng, Wanxu Huang, Yangqiu Li, Hengyou Weng

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation

Win Topatana, Sarun Juengpanich, Shijie Li, Jiasheng Cao, Jiahao Hu, Jiyoung Lee, Kenneth Suliyanto, Diana Ma, Bin Zhang, Mingyu Chen, Xiujun Cai

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases

He Li, Weixing Dai, Xi Xia, Renjie Wang, Jing Zhao, Lingyu Han, Shaobo Mo, Wenqiang Xiang, Lin Du, Guangya Zhu, Jingjing Xie, Jun Yu, Nan Liu, Mingzhu Huang, Jidong Zhu, Guoxiang Cai

07.09.2020 | COVID-19 | Research | Ausgabe 1/2020 Open Access

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

Si Zhang, Yangyang Liu, Xiaofang Wang, Li Yang, Haishan Li, Yuyan Wang, Mengduan Liu, Xiaoyan Zhao, Youhua Xie, Yan Yang, Shenghui Zhang, Zhichao Fan, Jianzeng Dong, Zhenghong Yuan, Zhongren Ding, Yi Zhang, Liang Hu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

tRNA-derived RNA fragments in cancer: current status and future perspectives

Mengqian Yu, Bingjian Lu, Jisong Zhang, Jinwang Ding, Pengyuan Liu, Yan Lu

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Efficacy and safety of CD19 CAR T constructed with a new anti-CD19 chimeric antigen receptor in relapsed or refractory acute lymphoblastic leukemia

Runxia Gu, Fang Liu, Dehui Zou, Yingxi Xu, Yang Lu, Bingcheng Liu, Wei Liu, Xiaojuan Chen, Kaiqi Liu, Ye Guo, Xiaoyuan Gong, Rui Lv, Xia Chen, Chunlin Zhou, Mengjun Zhong, Huijun Wang, Hui Wei, Yingchang Mi, Lugui Qiu, Lulu Lv, Min Wang, Ying Wang, Xiaofan Zhu, Jianxiang Wang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities

Young Sun Choi, Hyeonha Jang, Biki Gupta, Ji-Hak Jeong, Yun Ge, Chul Soon Yong, Jong Oh Kim, Jong-Sup Bae, Im-Sook Song, In-San Kim, You Mie Lee

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Current understanding of extrachromosomal circular DNA in cancer pathogenesis and therapeutic resistance

Yuanliang Yan, Guijie Guo, Jinzhou Huang, Ming Gao, Qian Zhu, Shuangshuang Zeng, Zhicheng Gong, Zhijie Xu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

BCMA-targeted immunotherapy for multiple myeloma

Bo Yu, Tianbo Jiang, Delong Liu

01.12.2020 | Review | Ausgabe 1/2020 Open Access

A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target

Andrea Ghelli Luserna di Rorà, Claudio Cerchione, Giovanni Martinelli, Giorgia Simonetti

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Advances in the assessment of minimal residual disease in mantle cell lymphoma

Dayoung Jung, Preetesh Jain, Yixin Yao, Michael Wang

01.12.2020 | Research | Ausgabe 1/2020 Open Access

A single-cell survey of cellular hierarchy in acute myeloid leukemia

Junqing Wu, Yanyu Xiao, Jie Sun, Huiyu Sun, Haide Chen, Yuanyuan Zhu, Huarui Fu, Chengxuan Yu, Weigao E., Shujing Lai, Lifeng Ma, Jiaqi Li, Lijiang Fei, Mengmeng Jiang, Jingjing Wang, Fang Ye, Renying Wang, Ziming Zhou, Guodong Zhang, Tingyue Zhang, Qiong Ding, Zou Wang, Sheng Hao, Lizhen Liu, Weiyan Zheng, Jingsong He, Weijia Huang, Yungui Wang, Jin Xie, Tiefeng Li, Tao Cheng, Xiaoping Han, He Huang, Guoji Guo

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals

Kasper Mønsted Pedersen, Yunus Çolak, Stig Egil Bojesen, Børge Grønne Nordestgaard

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma

Yunzhen Qian, Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu

01.12.2020 | COVID-19 | Letter to the Editor | Ausgabe 1/2020 Open Access

Severe COVID-19 virus reactivation following treatment for B cell acute lymphoblastic leukemia

Guido Lancman, John Mascarenhas, Michal Bar-Natan

01.12.2020 | Research | Ausgabe 1/2020 Open Access

Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML

Musa Yilmaz, Mansour Alfayez, Courtney D. DiNardo, Gautam Borthakur, Tapan M. Kadia, Marina Y. Konopleva, Sanam Loghavi, Rashmi Kanagal-Shamanna, Keyur P. Patel, Elias J. Jabbour, Guillermo Garcia-Manero, Naveen Pemmaraju, Sherry A. Pierce, Issa Ghayas, Nicholas J. Short, Guillermo Montalban-Bravo, Koichi Takahashi, Rita Assi, Ahmad S. Alotaibi, Maro Ohanian, Michael Andreeff, Jorge E. Cortes, Hagop M. Kantarjian, Farhad Ravandi, Naval G. Daver

01.12.2020 | COVID-19 | Research | Ausgabe 1/2020 Open Access

Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study

Julio García-Suárez, Javier de la Cruz, Ángel Cedillo, Pilar Llamas, Rafael Duarte, Víctor Jiménez-Yuste, José Ángel Hernández-Rivas, Rodrigo Gil-Manso, Mi Kwon, Pedro Sánchez-Godoy, Pilar Martínez-Barranco, Blanca Colás-Lahuerta, Pilar Herrera, Laurentino Benito-Parra, Adrián Alegre, Alberto Velasco, Arturo Matilla, María Concepción Aláez-Usón, Rafael Martos-Martínez, Carmen Martínez-Chamorro, Keina Susana-Quiroz, Juan Francisco Del Campo, Adolfo de la Fuente, Regina Herráez, Adriana Pascual, Elvira Gómez, Jaime Pérez-Oteyza, Elena Ruiz, Arancha Alonso, José González-Medina, Lucía Núñez Martín-Buitrago, Miguel Canales, Isabel González-Gascón, María Carmen Vicente-Ayuso, Susana Valenciano, María García Roa, Pablo Estival Monteliu, Javier López-Jiménez, Cristián Escolano Escobar, Javier Ortiz-Martín, José Luis Diez-Martin, Joaquín Martinez-Lopez, the Asociación Madrileña de Hematología y Hemoterapia (AMHH)

01.12.2020 | Review | Ausgabe 1/2020 Open Access

High-throughput approaches for precision medicine in high-grade serous ovarian cancer

Meinusha Govindarajan, Christoph Wohlmuth, Matthew Waas, Marcus Q. Bernardini, Thomas Kislinger

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

Lorena Zubovic, Silvano Piazza, Toma Tebaldi, Luca Cozzuto, Giuliana Palazzo, Viktoryia Sidarovich, Veronica De Sanctis, Roberto Bertorelli, Tim Lammens, Mattias Hofmans, Barbara De Moerloose, Julia Ponomarenko, Martina Pigazzi, Riccardo Masetti, Cristina Mecucci, Giuseppe Basso, Paolo Macchi

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Cancer stem cell secretome in the tumor microenvironment: a key point for an effective personalized cancer treatment

Julia López de Andrés, Carmen Griñán-Lisón, Gema Jiménez, Juan Antonio Marchal

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Prevention, recognition, and management of adverse events associated with gemtuzumab ozogamicin use in acute myeloid leukemia

Jorge E. Cortes, Marcos de Lima, Hervé Dombret, Elihu H. Estey, Sergio A. Giralt, Pau Montesinos, Christoph Röllig, Adriano Venditti, Eunice S. Wang

01.12.2020 | Review | Ausgabe 1/2020 Open Access

The functions and clinical significance of circRNAs in hematological malignancies

Xiangxiang Zhou, Linquan Zhan, Kai Huang, Xin Wang

01.12.2020 | Rapid communication | Ausgabe 1/2020 Open Access

Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

Lindsey T. Brinton, Pu Zhang, Katie Williams, Daniel Canfield, Shelley Orwick, Steven Sher, Ronni Wasmuth, Larry Beaver, Casey Cempre, Jordan Skinner, Matthew Cannon, Mukul Govande, Bonnie Harrington, Amy Lehman, John C. Byrd, Rosa Lapalombella, James S. Blachly

01.12.2020 | Letter to the Editor | Ausgabe 1/2020 Open Access

The specific distribution pattern of IKZF1 mutation in acute myeloid leukemia

Xiang Zhang, Xuewu Zhang, Xia Li, Yunfei Lv, Yanan Zhu, Jinghan Wang, Jie Jin, Wenjuan Yu

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