Ausgabe 1/2022
Inhalt (62 Artikel)
Therapy development for spinal muscular atrophy: perspectives for muscular dystrophies and neurodegenerative disorders
Sibylle Jablonka, Luisa Hennlein, Michael Sendtner
Neurological management and work-up of neurotoxicity associated with CAR T cell therapy
Nora Möhn, Viktoria Bonda, Lea Grote-Levi, Victoria Panagiota, Tabea Fröhlich, Christian Schultze-Florey, Mike P. Wattjes, Gernot Beutel, Matthias Eder, Sascha David, Sonja Körner, Günter Höglinger, Martin Stangel, Arnold Ganser, Christian Koenecke, Thomas Skripuletz
The special role of CXCL13 in Lyme neuroborreliosis: a case report
Deborah K. Erhart, Vera Bracknies, Susanne Lutz-Schuhbauer, Sonja Wigand, Hayrettin Tumani
Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol
Carolina B. Maciel, Fernanda J. P. Teixeira, Katie J. Dickinson, Jessica C. Spana, Lisa H. Merck, Alejandro A. Rabinstein, Robert Sergott, Guogen Shan, Guanhong Miao, Charles A. Peloquin, Katharina M. Busl, Lawrence J. Hirsch
Heterozygous POLG variant Ser1181Asn co-segregating in a family with autosomal dominant axonal neuropathy, proximal muscle fatigability, ptosis, and ragged red fibers
Maike F. Dohrn, Corina Heller, Diana Zengeler, Carolin D. Obermaier, Saskia Biskup, Joachim Weis, Stefan Nikolin, Kristl G. Claeys, Ulrike Schöne, Danique Beijer, Natalie Winter, Pascal Achenbach, Burkhard Gess, Jörg B. Schulz, Lejla Mulahasanovic
Guillain-Barré syndrome and fulminant encephalomyelitis following Ad26.COV2.S vaccination: double jeopardy
Maria Ioanna Stefanou, Eleni Karachaliou, Maria Chondrogianni, Christos Moschovos, Eleni Bakola, Aikaterini Foska, Konstantinos Melanis, Elisabeth Andreadou, Konstantinos Voumvourakis, Matilda Papathanasiou, Eleni Boutati, Georgios Tsivgoulis
SOP: thrombolysis in ischemic stroke under oral anticoagulation therapy
Pawel Kermer, Peter D. Schellinger, Peter A. Ringleb, Martin Köhrmann
Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a neuroradiological method to help differentiate from primary central nervous system vasculitis
Daniel Strunk, Roland Veltkamp, Sven G. Meuth, René Chapot, Markus Kraemer
Characterization of advanced Parkinson’s disease in Germany: results of the non-interventional OBSERVE-PD study
David J. Pedrosa, Florin Gandor, Wolfgang H. Jost, Carolin Arlt, Koray Onuk, Lars Timmermann
Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
Josef Finsterer, Fulvio A. Scorza, Carla A. Scorza, Ana C. Fiorini
Polyradiculitis and encephalomyelitis in the same patient following a SARS-CoV-2 vaccination
Josef Finsterer
Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease
Sylvia Thurn, Katharina Kleinschmidt, Irena Kovacic, Christina Wendl, Ralf A. Linker, Selim Corbacioglu, Felix Schlachetzki
A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers
Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S. Liebeskind, Felix Schlachetzki
A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of transcranial direct current stimulation to the motor cortex after stroke (NETS): study protocol
Christian Gerloff, Kirstin-Friederike Heise, Robert Schulz, Friedhelm C. Hummel, Silke Wolf, Antonia Zapf, Diana Cordes, Christian Gerloff, Kirstin-Friederike Heise, Friedhelm Hummel, Robert Schulz, Silke Wolf, Kerstin Haevernick, Heike Krüger, Linda Krause, Anna Suling, Karl Wegscheider, Antonia Zapf, Jürgen Dressnandt, Barbara Schäpers, Christoph Schrödl, Björn Hauptmann, Anja Kirchner, Anna Brault, Alexander Gutschalk, Constanze Richter, Dennis A. Nowak, Jitka Veldema, Giacomo Koch, Michele Maiella, Christian Dohle, Katrin Jettkowski, Mario Pilz, Farsin Hamzei, Lydia Olischer, Caroline Renner, Marcus Groß, Michael Jöbges, Bernhard Voller
On the quest for hidden ovarian teratomas in therapy-refractory anti-NMDA receptor encephalitis: a case report
Christoph Cirkel, Anna Cirkel, Georg Royl, Alex Frydrychowicz, Lars Tharun, Steffen Deichmann, Achim Rody, Thomas F. Münte, Björn Machner
Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry
Waltraud Pfeilschifter, Edelgard Lindhoff-Last, Ali Alhashim, Barbara Zydek, Simone Lindau, Stavros Konstantinides, Oliver Grottke, Ulrike Nowak-Göttl, Christian von Heymann, Ingvild Birschmann, Jan Beyer-Westendorf, Patrick Meybohm, Andreas Greinacher, Eva Herrmann
Residents as teachers in Neurology: a Germany-wide survey on the involvement of neurological residents in clinical teaching
Anne-Sophie Biesalski, Lars Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, Franziska Maria Ippen, Friederike Schmidt-Graf
Recovery of intracranial stenoses in varicella zoster virus vasculitis after long-term treatment with valacyclovir and prednisolone
Markus Kraemer, Daniel Strunk, Jana Becker, Roland Veltkamp, Peter Berlit
A look back at 3 years of neurological research and practice (NRP)
Werner Hacke
AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting programmed death-ligand 1 in isocitrate dehydrogenase 1 mutant gliomas
Lukas Bunse, Anne-Kathleen Rupp, Isabel Poschke, Theresa Bunse, Katharina Lindner, Antje Wick, Jens Blobner, Martin Misch, Ghazaleh Tabatabai, Martin Glas, Oliver Schnell, Jens Gempt, Monika Denk, Guido Reifenberger, Martin Bendszus, Patrick Wuchter, Joachim P Steinbach, Wolfgang Wick, Michael Platten
Long-term benefit of pallidal deep brain stimulation in a patient with VPS16-associated dystonia
Jan Niklas Petry-Schmelzer, Joohyun Park, Tobias B. Haack, Veerle Visser-Vandewalle, Michael T. Barbe, Gilbert Wunderlich
Exploring the relationships between composite scores of disease severity, seizure-freedom and quality of life in Dravet syndrome
Adam Strzelczyk, Gerhard Kurlemann, Thomas Bast, Ulrich Bettendorf, Gerhard Kluger, Thomas Mayer, Bernd A. Neubauer, Tilman Polster, Sarah von Spiczak, Regina Trollmann, Markus Wolff, Toby Toward, Jens Gruenert, Eddie Gibson, Clive Pritchard, Joe Carroll, Felix Rosenow, Susanne Schubert-Bast
Antiplatelets or anticoagulants? Secondary prevention in cervical artery dissection: an updated meta-analysis
Ei Zune The, Ne Naing Lin, Ching Jocelyn Chan, Jason Cher Wei Loon, Benjamin Yong-Qiang Tan, Chee Seong Raymond Seet, Hock Luen Teoh, Joy Vijayan, Leong Litt Leonard Yeo
LGI-1 encephalopathy following ChAdOx1 nCov-19 vaccination
Tamara Garibashvili, Josef Georg Heckmann
External ventricular drain use is associated with functional outcome in aneurysmal subarachnoid hemorrhage
Sarah E. Nelson, Jose I. Suarez, Alexander Sigmon, Jun Hua, Casey Weiner, Haris I. Sair, Robert D. Stevens
Historical review: the German Neurological Society and its honorary members (1952–1982)
Michael Martin, Heiner Fangerau, Axel Karenberg
COVID-19 outcomes in hospitalized Parkinson’s disease patients in two pandemic waves in 2020: a nationwide cross-sectional study from Germany
Raphael Scherbaum, Dirk Bartig, Daniel Richter, Eun Hae Kwon, Siegfried Muhlack, Ralf Gold, Christos Krogias, Lars Tönges
Neurological manifestations of post-COVID-19 syndrome S1-guideline of the German society of neurology
Christiana Franke, Peter Berlit, Harald Prüss
Anti-Homer-3 antibodies in cerebrospinal fluid and serum samples from a 58-year-old woman with subacute cerebellar degeneration and diffuse breast adenocarcinoma
Christof Klötzsch, Matthias Böhmert, Ruxandra Hermann, Bianca Teegen, Kristin Rentzsch, Andreas Till
Current diagnosis and treatment practice of central retinal artery occlusion: results from a survey among German stroke units
Carolin Hoyer, Simon Winzer, Egbert Matthé, Ida Heinle, Vesile Sandikci, Darius Nabavi, Michael Platten, Volker Puetz, Kristina Szabo
New concepts in neurology education: successful implementation of flipped classroom lectures
Katharina Mosene, Henrik Heitmann, Dennis Pötter, Friederike Schmidt-Graf
Single-center experience of induction therapy in non-systemic vasculitic neuropathy
Christian Schneider, Meike K. Wassermann, Gereon R. Fink, Helmar C. Lehmann
Carriers of POLG1 variants require investigations for multisystem disease and for mtDNA variations
Josef Finsterer, Sinda Zarrouk
Heterozygous POLG variant Ser1181Asn is associated with autosomal dominant neuro-myopathy in one family with no further specific manifestations of mitochondrial syndrome
Maike F. Dohrn, Danique Beijer, Lejla Mulahasanovic
Super-refractory status epilepticus in adults
Michael P Malter, Janina Neuneier
Regional computed tomography perfusion deficits in patients with hypoglycemia: two case reports
Jennifer Sartor-Pfeiffer, Mirjam Lingel, Maria-Ioanna Stefanou, Tobias Lindig, Benjamin Bender, Sven Poli, Ulf Ziemann, Andreas Fritsche, Katharina Feil, Annerose Mengel
Management of medication overuse (MO) and medication overuse headache (MOH) S1 guideline
Hans-Christoph Diener, Peter Kropp, Thomas Dresler, Stefan Evers, Stefanie Förderreuther, Charly Gaul, Dagny Holle-Lee, Arne May, Uwe Niederberger, Sabrina Moll, Christoph Schankin, Christian Lampl
Multifocal leukoencephalopathy associated with intensive use of cocaine and the adulterant levamisole in a 29-year old patient
Nadine Tollens, Philip Post, Michael Martins Dos Santos, Pascal Niggemann, Melanie Warken, Joachim Wolf
ADCY5-related dyskinesia: a case report
Shih-Ying Chen, Chen-Jui Ho, Yan-Ting Lu, Chih-Hsiang Lin, Meng-Han Tsai
Sudden vision loss and neurological deficits after facial hyaluronic acid filler injection
Alexandra Lucaciu, Patrick Felix Samp, Elke Hattingen, Roxane-Isabelle Kestner, Petra Davidova, Thomas Kohnen, Jasmin Rudolph, Andreas Dietz, Helmuth Steinmetz, Adam Strzelczyk
Essen transition model for neuromuscular diseases
Michael Fleischer, Bayram Coskun, Benjamin Stolte, Adela Della-Marina, Heike Kölbel, Hildegard Lax, Michael Nonnemacher, Christoph Kleinschnitz, Ulrike Schara-Schmidt, Tim Hagenacker
Antithrombotic treatment and outcome after endovascular treatment and acute carotid artery stenting in stroke patients with atrial fibrillation
Johannes M. Weller, Franziska Dorn, Julius N. Meissner, Sebastian Stösser, Niklas M. Beckonert, Julia Nordsiek, Christine Kindler, Christoph Riegler, Fee Keil, Gabor C. Petzold, Felix J. Bode, A. Reich, O. Nikoubashman, J. Röther, B. Eckert, M. Braun, G. F. Hamann, E. Siebert, C. H. Nolte, G. Bohner, R. M. Eckert, J. Borggrefe, P. Schellinger, J. Berrouschot, A. Bormann, C. Kraemer, H. Leischner, M. Petersen, F. Stögbauer, T Boeck-Behrens, S. Wunderlich, A. Ludolph, K. H. Henn, C. Gerloff, J. Fiehler, G. Thomalla, A. Alegiani, J. H. Schäfer, S. Tiedt, L. Kellert, C. Trumm, U. Ernemann, S. Poli, J. Liman, M. Ernst, K. Gröschel, T. Uphaus
Anti-flotillin-1/2 antibodies in a patient with neurogenic muscle atrophy and mild neuropsychological impairment
Tobias A. Wagner-Altendorf, Klaus-Peter Wandinger, Robert Markewitz, Anna Antufjew, Tobias Boppel, Thomas F. Münte
Impact of COVID-19 pandemic on physical and mental health status and care of adults with epilepsy in Germany
Kimberly Körbel, Felix Rosenow, Margarita Maltseva, Heiko Müller, Juliane Schulz, Panagiota-Eleni Tsalouchidou, Lisa Langenbruch, Stjepana Kovac, Katja Menzler, Mario Hamacher, Felix von Podewils, Laurent M. Willems, Catrin Mann, Adam Strzelczyk
Brain tumor related epilepsy: pathophysiological approaches and rational management of antiseizure medication
Sabine Seidel, Tim Wehner, Dorothea Miller, Jörg Wellmer, Uwe Schlegel, Wenke Grönheit
The impact of apraxia and neglect on early rehabilitation outcome after stroke
S. Latarnik, J. Stahl, S. Vossel, C. Grefkes, G. R. Fink, P. H. Weiss
Why cognitive training is important for the health status in Parkinson’s disease: preliminary evidence from a clinical three-weeks multidisciplinary intervention
Jennifer Michels, Cornelius J. Werner, Beate Schumann-Werner, Jörg B. Schulz, Ana S. Costa, Kathrin Reetz
Long-term efficacy with deep brain stimulation of the globus pallidus internus in cervical dystonia: a retrospective monocentric study
Clemens Jacksch, Kirsten E. Zeuner, Ann-Kristin Helmers, Karsten Witt, Günther Deuschl, Steffen Paschen
PET-MRI in idiopathic inflammatory myositis: a comparative study of clinical and immunological markers with imaging findings
Manu Santhappan Girija, Ravindu Tiwari, Seena Vengalil, Saraswati Nashi, Veeramani Preethish-Kumar, Kiran Polavarapu, Karthik Kulanthaivelu, Arpana Arbind, Mainak Bardhan, Akshata Huddar, Gopikrishnan Unnikrishnan, Valasani Ravi Kiran, Tanushree Chawla, Bevinahalli Nandeesh, Chandana Nagaraj, Atchayaram Nalini
Sex differences in etiology and short-term outcome in young ischemic stroke patients receiving mechanical thrombectomy
Ralph Weber, Evgenia Winezki, Aristeidis H. Katsanos, Melissa Cueillette, Karim Hajjar, Elif Yamac, Roland Veltkamp, Rene Chapot
Isolated slow orthostatic tremor of the trunk
N. Ahmad Aziz, Marcus Grobe-Einsler, Oliver Kaut
Does diabetes mellitus affect the safety profile of valproic acid for the treatment of status epilepticus? A retrospective cohort study
Annekatrin Müller, Judith von Hofen-Hohloch, Carolin Awissus, Jens Przybilla, Achmed Mrestani, Joseph Classen
No serological evidence for neuronal damage or reactive gliosis in neuro-COVID-19 patients with long-term persistent headache
Laura de Boni, Alexandru Odainic, Natalie Gancarczyk, Luisa Kaluza, Christian P. Strassburg, Xenia A. K. Kersting, Joseph M. Johnson, Ullrich Wüllner, Susanne V. Schmidt, Jacob Nattermann, Gabor C. Petzold
Anti-SEZ6L2 antibodies in paraneoplastic cerebellar syndrome: case report and review of the literature
Annika Kather, Florian Holtbernd, Robert Brunkhorst, Dimah Hasan, Robert Markewitz, Klaus-Peter Wandinger, Martin Wiesmann, Jörg B. Schulz, Simone C. Tauber
Real-world evidence on siponimod treatment in patients with secondary progressive multiple sclerosis
Liesa Regner-Nelke, Marc Pawlitzki, Alice Willison, Leoni Rolfes, Sinem-Hilal Oezalp, Christopher Nelke, Tristan Kölsche, Melanie Korsen, Matthias Grothe, Sergiu Groppa, Felix Luessi, Sinah Engel, Gereon Nelles, Eckhard Bonmann, Holger Roick, Anke Friedrich, Philipp Knorn, Harald Landefeld, Zoltan Biro, Michael Ernst, Antonios Bayas, Martina Menacher, Katja Akgün, Christoph Kleinschnitz, Tobias Ruck, Tjalf Ziemssen, Refik Pul, Sven G. Meuth
Teaching distinguishing semiological features improves diagnostic accuracy of seizure-like events by emergency physicians
Wenke Grönheit, Vanessa Behrens, Tatjana Liakina, Christoph Kellinghaus, Soheyl Noachtar, Stoyan Popkirov, Tim Wehner, Eva Brammen, Jörg Wellmer
Side matters: differences in functional outcome and quality of life after thrombectomy in left and right hemispheric stroke
Milani Deb-Chatterji, Fabian Flottmann, Lukas Meyer, Caspar Brekenfeld, Jens Fiehler, Christian Gerloff, Götz Thomalla, C. Gerloff, J. Fiehler, G. Thomalla, A. Alegiani, Boeckh-Behrens, Silke Wunderlich, Ulrike Ernemann, Sven Poli, Eberhard Siebert, Christian H. Nolte, Sarah Zweynert, Georg Bohner, Alexander Ludolph, Karl-Heinz Henn, Jan Hendrik Schäfer, Fee Keil, Joachim Röther, Bernd Eckert, Jörg Berrouschot, Albrecht Bormann, Franziska Dorn, Gabor Petzold, Christoffer Kraemer, Hannes Leischner, Christoph Trumm, Steffen Tiedt, Lars Kellert, Martina Petersen, Florian Stögbauer, Michael Braun, Gerhard F. Hamann, Klaus Gröschel, Timo Uphaus, Arno Reich, Omid Nikoubashman, Peter Schellinger, Jan Borggrefe, Jörg Hattingen, Jan Liman, Marielle Ernst
The gut-brain axis in ischemic stroke: its relevance in pathology and as a therapeutic target
Corinne Benakis, Arthur Liesz
Prognostic markers of post-stroke depression (PROMoSD): study protocol of a prospective single-center observational study on raphe hypoechogenicity as a predictor of post-stroke depression
Daniel Richter, Andreas Ebert, Lisa Mazul-Wach, Quirin Ruland, Jeyanthan Charles-James, Ralf Gold, Georgios Tsivgoulis, Georg Juckel, Christos Krogias
ALSFRS-R-SE: an adapted, annotated, and self-explanatory version of the revised amyotrophic lateral sclerosis functional rating scale
André Maier, Matthias Boentert, Peter Reilich, Simon Witzel, Susanne Petri, Julian Großkreutz, Moritz Metelmann, Paul Lingor, Isabell Cordts, Johannes Dorst, Daniel Zeller, René Günther, Tim Hagenacker, Torsten Grehl, Susanne Spittel, Joachim Schuster, Albert Ludolph, Thomas Meyer
Intravenous thrombolysis for acute ischemic stroke associated with known left ventricular thrombus: safe or not?
Sofia Kitmeridou, Dimitrios Tsiptsios, Dimos Tsalkidis, Evlampia A. Psatha, Ioannis Iliopoulos, Nikolaos Aggelousis, Konstantinos Vadikolias
Myositis in Germany: epidemiological insights over 15 years from 2005 to 2019
Marc Pawlitzki, Laura Acar, Lars Masanneck, Alice Willison, Liesa Regner-Nelke, Christopher Nelke, Helmut L’hoest, Ursula Marschall, Jens Schmidt, Sven G. Meuth, Tobias Ruck