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Erschienen in: European Radiology 4/2015

01.04.2015 | Musculoskeletal

Strain ratio measurement of femoral cartilage by real-time elastosonography: preliminary results

verfasst von: Nurdan Cay, Ali Ipek, Cetin Isik, Ozlem Unal, Merve Gulbiz Kartal, Halil Arslan, Murat Bozkurt

Erschienen in: European Radiology | Ausgabe 4/2015

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Abstract

Objective

The purpose of this study was to evaluate strain ratio measurement of femoral cartilage using real-time elastosonography.

Methods

Twenty-five patients with femoral cartilage pathology on MRI (study group) were prospectively compared with 25 subjects with normal findings on MRI (control group) using real-time elastosonography. Strain ratio measurements of pathologic and normal cartilage were performed and compared, both within the study group and between the two groups.

Results

Elastosonography colour-scale coding showed a colour change from blue to red in pathologic cartilage and only blue colour-coding in normal cartilage. In the study group, the median strain ratio was higher in pathologic cartilage areas compared to normal areas (median, 1.49 [interquartile range, 0.80–2.53] vs. median, 0.01 [interquartile range, 0.01–0.01], p < 0.001, respectively). The median strain ratio of the control group was 0.01 (interquartile range, 0.01–0.01), and there was no significant difference compared to normal areas of the study group. There was, however, a significant difference between the control group cartilage and pathologic cartilage of the study group (p < 0.001).

Conclusions

Elastosonography may be an effective, easily accessible, and relatively simple tool to demonstrate pathologic cartilage and to differentiate it from normal cartilage in the absence of advanced imaging facility such as MRI.

Key Points

Elastosonography uses colour-maps and strain ratios for evaluating tissue deformability.
Colour change from blue to red and increased strain ratio represent softening.
Normal cartilage shows decreased compressibility, represented by blue colour and low strain ratio.
Pathologic cartilage shows increased compressibility, represented by red colour and high strain ratio.
Elastosonography may be used for differentiating pathologic cartilage from normal cartilage.
Literatur
2.
Zurück zum Zitat Lee CL, Huang MH, Chai CY, Chen CH, Su JY, Tien YC (2008) The validity of in vivo ultrasonographic grading of osteoarthritic femoral condylar cartilage: a comparison with in vitro ultrasonographic and histologic gradings. Osteoarthr Cartil 16:352–358CrossRefPubMed Lee CL, Huang MH, Chai CY, Chen CH, Su JY, Tien YC (2008) The validity of in vivo ultrasonographic grading of osteoarthritic femoral condylar cartilage: a comparison with in vitro ultrasonographic and histologic gradings. Osteoarthr Cartil 16:352–358CrossRefPubMed
3.
Zurück zum Zitat Moller I, Bong D, Naredo E et al (2008) Ultrasound in the study and monitoring of osteoarthritis. Osteoarthr Cartil 16(Suppl 3):S4–7CrossRefPubMed Moller I, Bong D, Naredo E et al (2008) Ultrasound in the study and monitoring of osteoarthritis. Osteoarthr Cartil 16(Suppl 3):S4–7CrossRefPubMed
4.
Zurück zum Zitat Yoon CH, Kim HS, Ju JH, Jee WH, Park SH, Kim HY (2008) Validity of the sonographic longitudinal sagittal image for assessment of the cartilage thickness in the knee osteoarthritis. Clin Rheumatol 27:1507–1516CrossRefPubMed Yoon CH, Kim HS, Ju JH, Jee WH, Park SH, Kim HY (2008) Validity of the sonographic longitudinal sagittal image for assessment of the cartilage thickness in the knee osteoarthritis. Clin Rheumatol 27:1507–1516CrossRefPubMed
5.
Zurück zum Zitat Castriota-Scanderbeg A, De Micheli V, Scarale MG, Bonetti MG, Cammisa M (1996) Precision of sonographic measurement of articular cartilage: inter- and intraobserver analysis. Skelet Radiol 25:545–549CrossRef Castriota-Scanderbeg A, De Micheli V, Scarale MG, Bonetti MG, Cammisa M (1996) Precision of sonographic measurement of articular cartilage: inter- and intraobserver analysis. Skelet Radiol 25:545–549CrossRef
6.
Zurück zum Zitat Mathiesen O, Konradsen L, Torp-Pedersen S, Jorgensen U (2004) Ultrasonography and articular cartilage defects in the knee: an in vitro evaluation of the accuracy of cartilage thickness and defect size assessment. Knee Surg Sports Traumatol Arthrosc 12:440–443CrossRefPubMed Mathiesen O, Konradsen L, Torp-Pedersen S, Jorgensen U (2004) Ultrasonography and articular cartilage defects in the knee: an in vitro evaluation of the accuracy of cartilage thickness and defect size assessment. Knee Surg Sports Traumatol Arthrosc 12:440–443CrossRefPubMed
7.
Zurück zum Zitat Kara M, Tiftik T, Oken O, Akkaya N, Tunc H, Ozcakar L (2013) Ultrasonographic measurement of femoral cartilage thickness in patients with spinal cord injury. J Rehabil Med 45:145–148CrossRefPubMed Kara M, Tiftik T, Oken O, Akkaya N, Tunc H, Ozcakar L (2013) Ultrasonographic measurement of femoral cartilage thickness in patients with spinal cord injury. J Rehabil Med 45:145–148CrossRefPubMed
8.
Zurück zum Zitat Frey H (2003) Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity. Radiologe 43:850–855CrossRefPubMed Frey H (2003) Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity. Radiologe 43:850–855CrossRefPubMed
9.
Zurück zum Zitat Ophir J, Cespedes I, Ponnekanti H, Yazdi Y, Li X (1991) Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging 13:111–134CrossRefPubMed Ophir J, Cespedes I, Ponnekanti H, Yazdi Y, Li X (1991) Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging 13:111–134CrossRefPubMed
10.
Zurück zum Zitat De Zordo T, Lill SR, Fink C et al (2009) Real-time sonoelastography of lateral epicondylitis: comparison of findings between patients and healthy volunteers. AJR Am J Roentgenol 193:180–185CrossRefPubMed De Zordo T, Lill SR, Fink C et al (2009) Real-time sonoelastography of lateral epicondylitis: comparison of findings between patients and healthy volunteers. AJR Am J Roentgenol 193:180–185CrossRefPubMed
11.
Zurück zum Zitat De Zordo T, Fink C, Feuchtner GM, Smekal V, Reindl M, Klauser AS (2009) Real-time sonoelastography findings in healthy Achilles tendons. AJR Am J Roentgenol 193:W134–138CrossRefPubMed De Zordo T, Fink C, Feuchtner GM, Smekal V, Reindl M, Klauser AS (2009) Real-time sonoelastography findings in healthy Achilles tendons. AJR Am J Roentgenol 193:W134–138CrossRefPubMed
12.
Zurück zum Zitat Tan S, Kudas S, Ozcan AS et al (2012) Real-time sonoelastography of the Achilles tendon: pattern description in healthy subjects and patients with surgically repaired complete ruptures. Skelet Radiol 41:1067–1072CrossRef Tan S, Kudas S, Ozcan AS et al (2012) Real-time sonoelastography of the Achilles tendon: pattern description in healthy subjects and patients with surgically repaired complete ruptures. Skelet Radiol 41:1067–1072CrossRef
13.
Zurück zum Zitat Cho N, Jang M, Lyou CY, Park JS, Choi HY, Moon WK (2012) Distinguishing benign from malignant masses at breast US: combined US elastography and color Doppler US—influence on radiologist accuracy. Radiology 262:80–90CrossRefPubMed Cho N, Jang M, Lyou CY, Park JS, Choi HY, Moon WK (2012) Distinguishing benign from malignant masses at breast US: combined US elastography and color Doppler US—influence on radiologist accuracy. Radiology 262:80–90CrossRefPubMed
14.
Zurück zum Zitat Matzat SJ, van Tiel J, Gold GE, Oei EH (2013) Quantitative MRI techniques of cartilage composition. Quant Imaging Med Surg 3:162–174PubMedCentralPubMed Matzat SJ, van Tiel J, Gold GE, Oei EH (2013) Quantitative MRI techniques of cartilage composition. Quant Imaging Med Surg 3:162–174PubMedCentralPubMed
15.
Zurück zum Zitat Newbould RD, Miller SR, Upadhyay N et al (2013) T1-weighted sodium MRI of the articulator cartilage in osteoarthritis: a cross sectional and longitudinal study. PLoS One 8:e73067CrossRefPubMedCentralPubMed Newbould RD, Miller SR, Upadhyay N et al (2013) T1-weighted sodium MRI of the articulator cartilage in osteoarthritis: a cross sectional and longitudinal study. PLoS One 8:e73067CrossRefPubMedCentralPubMed
16.
Zurück zum Zitat Park GY, Kwon DR (2011) Application of real-time sonoelastography in musculoskeletal diseases related to physical medicine and rehabilitation. Am J Phys Med Rehabil 90:875–886CrossRefPubMed Park GY, Kwon DR (2011) Application of real-time sonoelastography in musculoskeletal diseases related to physical medicine and rehabilitation. Am J Phys Med Rehabil 90:875–886CrossRefPubMed
17.
Zurück zum Zitat Tan S, Ozcan MF, Tezcan F et al (2013) Real-time elastography for distinguishing angiomyolipoma from renal cell carcinoma: preliminary observations. AJR Am J Roentgenol 200:W369–375CrossRefPubMed Tan S, Ozcan MF, Tezcan F et al (2013) Real-time elastography for distinguishing angiomyolipoma from renal cell carcinoma: preliminary observations. AJR Am J Roentgenol 200:W369–375CrossRefPubMed
18.
Zurück zum Zitat Alam F, Naito K, Horiguchi J, Fukuda H, Tachikake T, Ito K (2008) Accuracy of sonographic elastography in the differential diagnosis of enlarged cervical lymph nodes: comparison with conventional B-mode sonography. AJR Am J Roentgenol 191:604–610CrossRefPubMed Alam F, Naito K, Horiguchi J, Fukuda H, Tachikake T, Ito K (2008) Accuracy of sonographic elastography in the differential diagnosis of enlarged cervical lymph nodes: comparison with conventional B-mode sonography. AJR Am J Roentgenol 191:604–610CrossRefPubMed
19.
Zurück zum Zitat Lyshchik A, Higashi T, Asato R et al (2005) Thyroid gland tumor diagnosis at US elastography. Radiology 237:202–211CrossRefPubMed Lyshchik A, Higashi T, Asato R et al (2005) Thyroid gland tumor diagnosis at US elastography. Radiology 237:202–211CrossRefPubMed
20.
Zurück zum Zitat Tunc H, Oken O, Kara M et al (2012) Ultrasonographic measurement of the femoral cartilage thickness in hemiparetic patients after stroke. Int J Rehabil Res 35:203–207PubMed Tunc H, Oken O, Kara M et al (2012) Ultrasonographic measurement of the femoral cartilage thickness in hemiparetic patients after stroke. Int J Rehabil Res 35:203–207PubMed
21.
Zurück zum Zitat Kaya A, Kara M, Tiftik T et al (2013) Ultrasonographic evaluation of the femoral cartilage thickness in patients with systemic lupus erythematosus. Rheumatol Int 33:899–901CrossRefPubMed Kaya A, Kara M, Tiftik T et al (2013) Ultrasonographic evaluation of the femoral cartilage thickness in patients with systemic lupus erythematosus. Rheumatol Int 33:899–901CrossRefPubMed
22.
Zurück zum Zitat Tatar IG, Kurt A, Yilmaz KB, Akinci M, Kulacoglu H, Hekimoglu B (2013) The learning curve of real time elastosonography: a preliminary study conducted for the assessment of malignancy risk in thyroid nodules. Med Ultrason 15:278–284CrossRefPubMed Tatar IG, Kurt A, Yilmaz KB, Akinci M, Kulacoglu H, Hekimoglu B (2013) The learning curve of real time elastosonography: a preliminary study conducted for the assessment of malignancy risk in thyroid nodules. Med Ultrason 15:278–284CrossRefPubMed
Metadaten
Titel
Strain ratio measurement of femoral cartilage by real-time elastosonography: preliminary results
verfasst von
Nurdan Cay
Ali Ipek
Cetin Isik
Ozlem Unal
Merve Gulbiz Kartal
Halil Arslan
Murat Bozkurt
Publikationsdatum
01.04.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 4/2015
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3497-y

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