Skip to main content
Erschienen in: Skeletal Radiology 12/2017

07.09.2017 | Review Article

Surgical considerations when reporting MRI studies of soft tissue sarcoma of the limbs

verfasst von: Marcela De La Hoz Polo, Elizabeth Dick, Rej Bhumbra, Rob Pollock, Ranbir Sandhu, Asif Saifuddin

Erschienen in: Skeletal Radiology | Ausgabe 12/2017

Einloggen, um Zugang zu erhalten

Abstract

Soft tissue sarcomas (STS) are rare tumours that require prompt diagnosis and treatment at a specialist centre. Magnetic resonance imaging (MRI) has become the modality of choice for identification, characterisation, biopsy planning and staging of soft tissue masses. MRI enables both the operating surgeon and patient to be optimally prepared prior to surgery for the likelihood of margin-negative resection and to anticipate possible sacrifice of adjacent structures and consequent loss of function. The aim of this review is to aid the radiologist in performing and reporting MRI studies of soft tissue sarcomas, with particular reference to the requirements of the surgical oncologist.
Literatur
1.
Zurück zum Zitat Hajdu SI. Soft tissue sarcomas: classification and natural history. CA Cancer J Clin. 1981;31:271–80.CrossRefPubMed Hajdu SI. Soft tissue sarcomas: classification and natural history. CA Cancer J Clin. 1981;31:271–80.CrossRefPubMed
2.
Zurück zum Zitat Fletcher C, Bridge J, Hogendoorn P, Mertens F, editors. World Health Organization classification of tumours of soft tissue and bone: pathology and genetics of tumours of soft tissue and bone. 4th ed. Lyon, France: IARC Press; 2013. Fletcher C, Bridge J, Hogendoorn P, Mertens F, editors. World Health Organization classification of tumours of soft tissue and bone: pathology and genetics of tumours of soft tissue and bone. 4th ed. Lyon, France: IARC Press; 2013.
3.
Zurück zum Zitat ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25(Suppl 3:iii):102–12.CrossRef ESMO/European Sarcoma Network Working Group. Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25(Suppl 3:iii):102–12.CrossRef
5.
Zurück zum Zitat van Vliet M, Kliffen M, Krestin GP, Van Dijke CF. Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors. Eur Radiol. 2009;19(6):1499–511.CrossRefPubMed van Vliet M, Kliffen M, Krestin GP, Van Dijke CF. Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors. Eur Radiol. 2009;19(6):1499–511.CrossRefPubMed
6.
Zurück zum Zitat Noebauer-Huhmann IM, Weber MA, Lalam RK, et al. Soft tissue tumors in adults: ESSR-approved guidelines for diagnostic imaging. Semin Musculoskelet Radiol. 2015;19:475–82.CrossRefPubMed Noebauer-Huhmann IM, Weber MA, Lalam RK, et al. Soft tissue tumors in adults: ESSR-approved guidelines for diagnostic imaging. Semin Musculoskelet Radiol. 2015;19:475–82.CrossRefPubMed
7.
Zurück zum Zitat Bauer HC, Trovik CS, Alvegård TA, Berlin O, Erlanson M, Gustafson P, et al. Monitoring referral and treatment in soft tissue sarcoma: study based on 1,851 patients from the scandinavian sarcoma group register. Acta Orthop Scand. 2001, Apr;72:150–9.CrossRefPubMed Bauer HC, Trovik CS, Alvegård TA, Berlin O, Erlanson M, Gustafson P, et al. Monitoring referral and treatment in soft tissue sarcoma: study based on 1,851 patients from the scandinavian sarcoma group register. Acta Orthop Scand. 2001, Apr;72:150–9.CrossRefPubMed
8.
Zurück zum Zitat Grimer R, Athanasou N, Gerrand C, et al. UK guidelines for the management of bone sarcomas. Sarcoma. 2010;2010:317462.PubMedPubMedCentral Grimer R, Athanasou N, Gerrand C, et al. UK guidelines for the management of bone sarcomas. Sarcoma. 2010;2010:317462.PubMedPubMedCentral
9.
Zurück zum Zitat LeVay J, O’sullivan B, Catton C, et al. Outcome and prognostic factors in soft tissue sarcoma in the adult. Int J Radiat Oncol Biol Phys. 1993;27:1091–9.CrossRefPubMed LeVay J, O’sullivan B, Catton C, et al. Outcome and prognostic factors in soft tissue sarcoma in the adult. Int J Radiat Oncol Biol Phys. 1993;27:1091–9.CrossRefPubMed
10.
Zurück zum Zitat Robinson E, Bleakney RR, Ferguson PC, O’Sullivan B. Oncodiagnosis panel: 2007: multidisciplinary management of soft-tissue sarcoma. Radiographics. 2008;28:2069–86.CrossRefPubMed Robinson E, Bleakney RR, Ferguson PC, O’Sullivan B. Oncodiagnosis panel: 2007: multidisciplinary management of soft-tissue sarcoma. Radiographics. 2008;28:2069–86.CrossRefPubMed
11.
Zurück zum Zitat Dalinka MK, Zlatkin MB, Chao P, Kricun ME, Kressel HY. The use of magnetic resonance imaging in the evaluation of bone and soft-tissue tumors. Radiol Clin N Am. 1990;28:461–70.PubMed Dalinka MK, Zlatkin MB, Chao P, Kricun ME, Kressel HY. The use of magnetic resonance imaging in the evaluation of bone and soft-tissue tumors. Radiol Clin N Am. 1990;28:461–70.PubMed
12.
Zurück zum Zitat Elias DA, White LM, Simpson DJ, et al. Osseous invasion by soft-tissue sarcoma: assessment with MR imaging. Radiology. 2003;229:145–52.CrossRefPubMed Elias DA, White LM, Simpson DJ, et al. Osseous invasion by soft-tissue sarcoma: assessment with MR imaging. Radiology. 2003;229:145–52.CrossRefPubMed
13.
Zurück zum Zitat Panicek DM, Go SD, Healey JH, Leung DH, Brennan MF, Lewis JJ. Soft-tissue sarcoma involving bone or neurovascular structures: MR imaging prognostic factors. Radiology. 1997;205:871–5.CrossRefPubMed Panicek DM, Go SD, Healey JH, Leung DH, Brennan MF, Lewis JJ. Soft-tissue sarcoma involving bone or neurovascular structures: MR imaging prognostic factors. Radiology. 1997;205:871–5.CrossRefPubMed
14.
Zurück zum Zitat Kransdorf MJ, Murphey MD. Imaging of soft-tissue musculoskeletal masses: fundamental concepts. Radiographics. 2016;36:1931–48.CrossRefPubMed Kransdorf MJ, Murphey MD. Imaging of soft-tissue musculoskeletal masses: fundamental concepts. Radiographics. 2016;36:1931–48.CrossRefPubMed
15.
Zurück zum Zitat Khoo MM, Saifuddin A. The role of MRI in image-guided needle biopsy of focal bone and soft tissue neoplasms. Skelet Radiol. 2013;42:905–15.CrossRef Khoo MM, Saifuddin A. The role of MRI in image-guided needle biopsy of focal bone and soft tissue neoplasms. Skelet Radiol. 2013;42:905–15.CrossRef
16.
Zurück zum Zitat Manaster BJ. Soft-tissue masses: optimal imaging protocol and reporting. AJR Am J Roentgenol. 2013;201:505–14.CrossRefPubMed Manaster BJ. Soft-tissue masses: optimal imaging protocol and reporting. AJR Am J Roentgenol. 2013;201:505–14.CrossRefPubMed
17.
Zurück zum Zitat Holzapfel K, Regler J, Baum T, et al. Local staging of soft-tissue sarcoma: emphasis on assessment of neurovascular encasementvalue of MR imaging in 174 confirmed cases. Radiology. 2015;275:501–9.CrossRefPubMed Holzapfel K, Regler J, Baum T, et al. Local staging of soft-tissue sarcoma: emphasis on assessment of neurovascular encasementvalue of MR imaging in 174 confirmed cases. Radiology. 2015;275:501–9.CrossRefPubMed
18.
Zurück zum Zitat Kransdorf MJ, Murphey MD. Radiologic evaluation of soft-tissue masses: a current perspective. AJR Am J Roentgenol. 2000;175:575–87.CrossRefPubMed Kransdorf MJ, Murphey MD. Radiologic evaluation of soft-tissue masses: a current perspective. AJR Am J Roentgenol. 2000;175:575–87.CrossRefPubMed
19.
Zurück zum Zitat Verstraete KL, Lang P. Bone and soft tissue tumors: the role of contrast agents for MR imaging. Eur J Radiol. 2000;34:229–46.CrossRefPubMed Verstraete KL, Lang P. Bone and soft tissue tumors: the role of contrast agents for MR imaging. Eur J Radiol. 2000;34:229–46.CrossRefPubMed
20.
Zurück zum Zitat Belli P, Costantini M, Mirk P, Maresca G, Priolo F, Marano P. Role of color doppler sonography in the assessment of musculoskeletal soft tissue masses. J Ultrasound Med. 2000;19:823–30.CrossRefPubMed Belli P, Costantini M, Mirk P, Maresca G, Priolo F, Marano P. Role of color doppler sonography in the assessment of musculoskeletal soft tissue masses. J Ultrasound Med. 2000;19:823–30.CrossRefPubMed
21.
Zurück zum Zitat Khoo MM, Tyler PA, Saifuddin A, Padhani AR. Diffusion-weighted imaging (DWI) in musculoskeletal MRI: a critical review. Skelet Radiol. 2011;40:665–81.CrossRef Khoo MM, Tyler PA, Saifuddin A, Padhani AR. Diffusion-weighted imaging (DWI) in musculoskeletal MRI: a critical review. Skelet Radiol. 2011;40:665–81.CrossRef
22.
Zurück zum Zitat Teixeira PA, Beaumont M, Gabriela H, et al. Advanced techniques in musculoskeletal oncology: perfusion, diffusion, and spectroscopy. Semin Musculoskelet Radiol. 2015;19:463–74.CrossRefPubMed Teixeira PA, Beaumont M, Gabriela H, et al. Advanced techniques in musculoskeletal oncology: perfusion, diffusion, and spectroscopy. Semin Musculoskelet Radiol. 2015;19:463–74.CrossRefPubMed
23.
Zurück zum Zitat Wu JS, Hochman MG. Soft-tissue tumors and tumorlike lesions: a systematic imaging approach. Radiology. 2009;253:297–316.CrossRefPubMed Wu JS, Hochman MG. Soft-tissue tumors and tumorlike lesions: a systematic imaging approach. Radiology. 2009;253:297–316.CrossRefPubMed
24.
Zurück zum Zitat Crundwell N, O’Donnell P, Saifuddin A. Nonneoplastic conditions presenting as soft-tissue tumors: pictorial review. Clin Radiol. 2007;62:18–27.CrossRefPubMed Crundwell N, O’Donnell P, Saifuddin A. Nonneoplastic conditions presenting as soft-tissue tumors: pictorial review. Clin Radiol. 2007;62:18–27.CrossRefPubMed
25.
Zurück zum Zitat Goodwin RW, O’Donnell P, Saifuddin A. MRI appearances of common benign soft-tissue tumours. Clin Radiol. 2007;62:843–53.CrossRefPubMed Goodwin RW, O’Donnell P, Saifuddin A. MRI appearances of common benign soft-tissue tumours. Clin Radiol. 2007;62:843–53.CrossRefPubMed
26.
Zurück zum Zitat O’Regan KN, Jagannathan J, Krajewski K, et al. Imaging of liposarcoma: classification, patterns of tumor recurrence, and response to treatment. AJR Am J Roentgenol. 2011;197:W37–43.CrossRefPubMed O’Regan KN, Jagannathan J, Krajewski K, et al. Imaging of liposarcoma: classification, patterns of tumor recurrence, and response to treatment. AJR Am J Roentgenol. 2011;197:W37–43.CrossRefPubMed
27.
Zurück zum Zitat Baheti AD, Tirumani SH, Rosenthal MH, et al. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015;204:374–85.CrossRefPubMed Baheti AD, Tirumani SH, Rosenthal MH, et al. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015;204:374–85.CrossRefPubMed
28.
Zurück zum Zitat Suresh S, Saifuddin A, O’Donnell P. Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases. Eur Radiol. 2008;18:2628–34.CrossRefPubMed Suresh S, Saifuddin A, O’Donnell P. Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases. Eur Radiol. 2008;18:2628–34.CrossRefPubMed
29.
Zurück zum Zitat Crim JR, Seeger LL, Yao L, Chandnani V, Eckardt JJ. Diagnosis of soft-tissue masses with MR imaging: can benign masses be differentiated from malignant ones? Radiology. 1992;185:581–6.CrossRefPubMed Crim JR, Seeger LL, Yao L, Chandnani V, Eckardt JJ. Diagnosis of soft-tissue masses with MR imaging: can benign masses be differentiated from malignant ones? Radiology. 1992;185:581–6.CrossRefPubMed
30.
Zurück zum Zitat Berquist TH, Ehman RL, King BF, Hodgman CG, Ilstrup DM. Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions. AJR Am J Roentgenol. 1990;155:1251–5.CrossRefPubMed Berquist TH, Ehman RL, King BF, Hodgman CG, Ilstrup DM. Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions. AJR Am J Roentgenol. 1990;155:1251–5.CrossRefPubMed
31.
Zurück zum Zitat Gerrand CH, Wunder JS, Kandel RA, et al. Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J Bone Joint Surg Br. 2001;83:1149–55.CrossRefPubMed Gerrand CH, Wunder JS, Kandel RA, et al. Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J Bone Joint Surg Br. 2001;83:1149–55.CrossRefPubMed
32.
Zurück zum Zitat Jalgaonkar A, Dawson-Bowling SJ, Mohan AT, et al. Identification of the biopsy track in musculoskeletal tumour surgery: a novel technique using india ink. Bone Joint J. 2013;95-B:250–3.CrossRefPubMed Jalgaonkar A, Dawson-Bowling SJ, Mohan AT, et al. Identification of the biopsy track in musculoskeletal tumour surgery: a novel technique using india ink. Bone Joint J. 2013;95-B:250–3.CrossRefPubMed
33.
Zurück zum Zitat Amin MB, Edge S, Greene F, et al (eds). 2017 AJCC cancer staging manual, 8th edition. Amin MB, Edge S, Greene F, et al (eds). 2017 AJCC cancer staging manual, 8th edition.
34.
Zurück zum Zitat Anderson MW, Temple HT, Dussault RG, Kaplan PA. Compartmental anatomy: relevance to staging and biopsy of musculoskeletal tumors. AJR Am J Roentgenol. 1999;173:1663–71.CrossRefPubMed Anderson MW, Temple HT, Dussault RG, Kaplan PA. Compartmental anatomy: relevance to staging and biopsy of musculoskeletal tumors. AJR Am J Roentgenol. 1999;173:1663–71.CrossRefPubMed
35.
Zurück zum Zitat Galant J, Martí-Bonmatí L, Soler R, et al. Grading of subcutaneous soft tissue tumors by means of their relationship with the superficial fascia on MR imaging. Skelet Radiol. 1998;27:657–63.CrossRef Galant J, Martí-Bonmatí L, Soler R, et al. Grading of subcutaneous soft tissue tumors by means of their relationship with the superficial fascia on MR imaging. Skelet Radiol. 1998;27:657–63.CrossRef
36.
Zurück zum Zitat Yoo HJ, Hong SH, Kang Y, et al. MR imaging of myxofibrosarcoma and undifferentiated sarcoma with emphasis on tail sign; diagnostic and prognostic value. Eur Radiol. 2014;24:1749–57.CrossRefPubMed Yoo HJ, Hong SH, Kang Y, et al. MR imaging of myxofibrosarcoma and undifferentiated sarcoma with emphasis on tail sign; diagnostic and prognostic value. Eur Radiol. 2014;24:1749–57.CrossRefPubMed
37.
Zurück zum Zitat Lefkowitz RA, Landa J, Hwang S, et al. Myxofibrosarcoma: prevalence and diagnostic value of the "tail sign" on magnetic resonance imaging. Skelet Radiol. 2013;42(6):809–18.CrossRef Lefkowitz RA, Landa J, Hwang S, et al. Myxofibrosarcoma: prevalence and diagnostic value of the "tail sign" on magnetic resonance imaging. Skelet Radiol. 2013;42(6):809–18.CrossRef
38.
Zurück zum Zitat Panicek DM, Gatsonis C, Rosenthal DI, et al. CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: report of the radiology diagnostic oncology group. Radiology. 1997;202:237–46.CrossRefPubMed Panicek DM, Gatsonis C, Rosenthal DI, et al. CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: report of the radiology diagnostic oncology group. Radiology. 1997;202:237–46.CrossRefPubMed
39.
Zurück zum Zitat Khosa F, Otero HJ, Prevedello LM, Rybicki FJ, Di Salvo DN. Imaging presentation of venous thrombosis in patients with cancer. AJR Am J Roentgenol. 2010;194:1099–108.CrossRefPubMed Khosa F, Otero HJ, Prevedello LM, Rybicki FJ, Di Salvo DN. Imaging presentation of venous thrombosis in patients with cancer. AJR Am J Roentgenol. 2010;194:1099–108.CrossRefPubMed
40.
Zurück zum Zitat Ferguson PC, Griffin AM, O’Sullivan B, et al. Bone invasion in extremity soft-tissue sarcoma: impact on disease outcomes. Cancer. 2006;106:2692–700.CrossRefPubMed Ferguson PC, Griffin AM, O’Sullivan B, et al. Bone invasion in extremity soft-tissue sarcoma: impact on disease outcomes. Cancer. 2006;106:2692–700.CrossRefPubMed
41.
Zurück zum Zitat Ferguson PC, Kulidjian AA, Jones KB, Deheshi BM, Wunder JS. Peripheral nerve considerations in the management of extremity soft tissue sarcomas. Recent Results Cancer Res. 2009;179:243–56.CrossRefPubMed Ferguson PC, Kulidjian AA, Jones KB, Deheshi BM, Wunder JS. Peripheral nerve considerations in the management of extremity soft tissue sarcomas. Recent Results Cancer Res. 2009;179:243–56.CrossRefPubMed
42.
Zurück zum Zitat Stotter A, McLean NR, Fallowfield ME, Breach NM, Westbury G. Reconstruction after excision of soft tissue sarcomas of the limbs and trunk. Br J Surg. 1988;75:774–8.CrossRefPubMed Stotter A, McLean NR, Fallowfield ME, Breach NM, Westbury G. Reconstruction after excision of soft tissue sarcomas of the limbs and trunk. Br J Surg. 1988;75:774–8.CrossRefPubMed
43.
Zurück zum Zitat Schwab JH, Boland PJ, Antonescu C, Bilsky MH, Healey JH. Spinal metastases from myxoid liposarcoma warrant screening with magnetic resonance imaging. Cancer. 2007;110:1815–22.CrossRefPubMed Schwab JH, Boland PJ, Antonescu C, Bilsky MH, Healey JH. Spinal metastases from myxoid liposarcoma warrant screening with magnetic resonance imaging. Cancer. 2007;110:1815–22.CrossRefPubMed
44.
Zurück zum Zitat Mendenhall WM, Indelicato DJ, Scarborough MT, Zlotecki RA, Gibbs CP, Mendenhall NP, et al. The management of adult soft tissue sarcomas. Am J Clin Oncol. 2009;32:436–42.CrossRefPubMed Mendenhall WM, Indelicato DJ, Scarborough MT, Zlotecki RA, Gibbs CP, Mendenhall NP, et al. The management of adult soft tissue sarcomas. Am J Clin Oncol. 2009;32:436–42.CrossRefPubMed
46.
Zurück zum Zitat Cable MG, Randall RL. Extremity soft tissue sarcoma: tailoring resection to histologic subtype. Surg Oncol Clin N Am. 2016;25:677–95.CrossRefPubMed Cable MG, Randall RL. Extremity soft tissue sarcoma: tailoring resection to histologic subtype. Surg Oncol Clin N Am. 2016;25:677–95.CrossRefPubMed
47.
Zurück zum Zitat Clarkson PW, Griffin AM, Catton CN, et al. Epineural dissection is a safe technique that facilitates limb salvage surgery. Clin Orthop Relat Res. 2005;438:92–6.CrossRefPubMed Clarkson PW, Griffin AM, Catton CN, et al. Epineural dissection is a safe technique that facilitates limb salvage surgery. Clin Orthop Relat Res. 2005;438:92–6.CrossRefPubMed
48.
Zurück zum Zitat Lee GW, Mackinnon SE, Brandt K, Bell RS. A technique for nerve reconstruction following resection of soft-tissue sarcoma. J Reconstr Microsurg. 1993;9:139–44.CrossRefPubMed Lee GW, Mackinnon SE, Brandt K, Bell RS. A technique for nerve reconstruction following resection of soft-tissue sarcoma. J Reconstr Microsurg. 1993;9:139–44.CrossRefPubMed
49.
Zurück zum Zitat Fuchs B, Davis AM, Wunder JS, Bell RS, Masri BA, Isler M, et al. Sciatic nerve resection in the thigh: a functional evaluation. Clin Orthop Relat Res. 2001;382:34–41.CrossRef Fuchs B, Davis AM, Wunder JS, Bell RS, Masri BA, Isler M, et al. Sciatic nerve resection in the thigh: a functional evaluation. Clin Orthop Relat Res. 2001;382:34–41.CrossRef
50.
51.
Zurück zum Zitat O’Sullivan B, Davis AM, Turcotte R, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet. 2002;359:2235–41.CrossRefPubMed O’Sullivan B, Davis AM, Turcotte R, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet. 2002;359:2235–41.CrossRefPubMed
52.
Zurück zum Zitat Dickie CI, Parent AL, Griffin AM, et al. Bone fractures following external beam radiotherapy and limb-preservation surgery for lower extremity soft tissue sarcoma: relationship to irradiated bone length, volume, tumor location and dose. Int J Radiat Oncol Biol Phys. 2009;75:1119–24.CrossRefPubMed Dickie CI, Parent AL, Griffin AM, et al. Bone fractures following external beam radiotherapy and limb-preservation surgery for lower extremity soft tissue sarcoma: relationship to irradiated bone length, volume, tumor location and dose. Int J Radiat Oncol Biol Phys. 2009;75:1119–24.CrossRefPubMed
53.
Zurück zum Zitat Pitson G, Robinson P, Wilke D, et al. Radiation response: An additional unique signature of myxoid liposarcoma. Int J Radiat Oncol Biol Phys. 2004;60:522–6.CrossRefPubMed Pitson G, Robinson P, Wilke D, et al. Radiation response: An additional unique signature of myxoid liposarcoma. Int J Radiat Oncol Biol Phys. 2004;60:522–6.CrossRefPubMed
54.
Zurück zum Zitat Delisca GO, Alamanda VK, Archer KR, Song Y, Schwartz HS, Holt GE. Tumor size increase following preoperative radiation of soft tissue sarcomas does not affect prognosis. J Surg Oncol. 2013;107:723–7.CrossRefPubMed Delisca GO, Alamanda VK, Archer KR, Song Y, Schwartz HS, Holt GE. Tumor size increase following preoperative radiation of soft tissue sarcomas does not affect prognosis. J Surg Oncol. 2013;107:723–7.CrossRefPubMed
55.
Zurück zum Zitat Biau DJ, Weiss KR, Bhumbra RS, et al. Monitoring the adequacy of surgical margins after resection of bone and soft-tissue sarcoma. Ann Surg Oncol. 2013:1858–64. Biau DJ, Weiss KR, Bhumbra RS, et al. Monitoring the adequacy of surgical margins after resection of bone and soft-tissue sarcoma. Ann Surg Oncol. 2013:1858–64.
56.
57.
Zurück zum Zitat Woll PJ, Reichardt P, Le Cesne A, et al. EORTC soft tissue and bone sarcoma group and the NCIC clinical trials group sarcoma disease site committee. Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial. Lancet Oncol. 2012;13:1045–54.CrossRefPubMed Woll PJ, Reichardt P, Le Cesne A, et al. EORTC soft tissue and bone sarcoma group and the NCIC clinical trials group sarcoma disease site committee. Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial. Lancet Oncol. 2012;13:1045–54.CrossRefPubMed
Metadaten
Titel
Surgical considerations when reporting MRI studies of soft tissue sarcoma of the limbs
verfasst von
Marcela De La Hoz Polo
Elizabeth Dick
Rej Bhumbra
Rob Pollock
Ranbir Sandhu
Asif Saifuddin
Publikationsdatum
07.09.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 12/2017
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-017-2745-z

Weitere Artikel der Ausgabe 12/2017

Skeletal Radiology 12/2017 Zur Ausgabe

Test Yourself: Question

Steifer und schmerzender Fuß

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.