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Erschienen in: European Radiology 11/2014

01.11.2014 | Neuro

The accuracy and utility of contrast-enhanced MR angiography for localization of spinal dural arteriovenous fistulas: the Toronto experience

verfasst von: Arjen Lindenholz, Karel G. TerBrugge, J. Marc C. van Dijk, Richard I. Farb

Erschienen in: European Radiology | Ausgabe 11/2014

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Abstract

Objectives

The purpose of this study was to determine the accuracy and utility of contrast-enhanced MR angiography (CE-MRA) in spinal dural arteriovenous fistulas (SDAVF).

Methods

A retrospective analysis from 1999–2012 identified 70 patients clinically suspected of harboring a SDAVF. Each patient underwent consecutive conventional MR-imaging, CE-MRA, and digital subtraction angiography (DSA). The presence or absence of serpentine flow voids, T2-weighted hyperintensity, and cord enhancement were evaluated, as well as location of the fistula as predicted by CE-MRA. DSA was used as the reference standard.

Results

Of the 70 cases, 53 were determined to be a SDAVF, 10 cases were shown to be other forms of vascular malformation, and 7 were DSA-negative. On MRI, all reported cases of SDAVF showed serpentine flow voids (100 %). T2-weighted hyperintensity was seen in 48 of 50 cases (96 %), extending to the conus in 41 of 48 cases (85 %). Cord enhancement was seen in 38 of 41 cases (93 %). CE-MRA correctly localized the SDAVF in 43 of the 53 cases (81 %).

Conclusions

CE-MRA is a useful non-invasive examination for the detection and localization of SDAVF. CE-MRA facilitates but does not replace DSA as confirmation of location, fistula type, and arterial detail, which are required before treatment.

Key Points

CE-MRA correctly localized the site of the SDAVF in over 80 % of cases.
CE-MRA facilitates diagnostic DSA and expedites the diagnostic process.
CE-MRA does not replace diagnostic DSA in SDAVF cases as confirmative test.
CE-MRA provides better understanding of missed or mislocalized SDAVF cases.
Literatur
1.
Zurück zum Zitat Narvid J, Hetts SW, Larsen D et al (2008) Spinal dural arteriovenous fistulae: clinical features and long-term results. Neurosurgery 62:159–166, discussion 166–157PubMedCrossRef Narvid J, Hetts SW, Larsen D et al (2008) Spinal dural arteriovenous fistulae: clinical features and long-term results. Neurosurgery 62:159–166, discussion 166–157PubMedCrossRef
2.
Zurück zum Zitat Van Dijk JM, TerBrugge KG, Willinsky RA et al (2002) Multidisciplinary management of spinal dural arteriovenous fistulas: clinical presentation and long-term follow-up in 49 patients. Stroke 33:1578–1583PubMedCrossRef Van Dijk JM, TerBrugge KG, Willinsky RA et al (2002) Multidisciplinary management of spinal dural arteriovenous fistulas: clinical presentation and long-term follow-up in 49 patients. Stroke 33:1578–1583PubMedCrossRef
3.
Zurück zum Zitat Krings T, Geibprasert S (2009) Spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol 30:639–648PubMedCrossRef Krings T, Geibprasert S (2009) Spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol 30:639–648PubMedCrossRef
4.
Zurück zum Zitat McCutcheon IE, Doppman JL, Oldfield EH (1996) Microvascular anatomy of dural arteriovenous abnormalities of the spine: a microangiographic study. J Neurosurg 84:215–220PubMedCrossRef McCutcheon IE, Doppman JL, Oldfield EH (1996) Microvascular anatomy of dural arteriovenous abnormalities of the spine: a microangiographic study. J Neurosurg 84:215–220PubMedCrossRef
5.
Zurück zum Zitat Aminoff MJ, Barnard RO, Logue V (1974) The pathophysiology of spinal vascular malformations. J Neurol Sci 23:255–263PubMedCrossRef Aminoff MJ, Barnard RO, Logue V (1974) The pathophysiology of spinal vascular malformations. J Neurol Sci 23:255–263PubMedCrossRef
6.
Zurück zum Zitat Toossi S, Josephson SA, Hetts SW et al (2012) Utility of MRI in spinal arteriovenous fistula. Neurology 79:25–30PubMedCrossRef Toossi S, Josephson SA, Hetts SW et al (2012) Utility of MRI in spinal arteriovenous fistula. Neurology 79:25–30PubMedCrossRef
7.
Zurück zum Zitat Muralidharan R, Saladino A, Lanzino G et al (2011) The clinical and radiological presentation of spinal dural arteriovenous fistula. Spine (Phila Pa 1976) 36:E1641–E1647CrossRef Muralidharan R, Saladino A, Lanzino G et al (2011) The clinical and radiological presentation of spinal dural arteriovenous fistula. Spine (Phila Pa 1976) 36:E1641–E1647CrossRef
8.
Zurück zum Zitat Jackson JPS (2003) Imaging of spinal cord vascular malformations. Oper Tech Neurosurg 6:125–140CrossRef Jackson JPS (2003) Imaging of spinal cord vascular malformations. Oper Tech Neurosurg 6:125–140CrossRef
9.
Zurück zum Zitat Gilbertson JR, Miller GM, Goldman MS et al (1995) Spinal dural arteriovenous fistulas: MR and myelographic findings. AJNR Am J Neuroradiol 16:2049–2057PubMed Gilbertson JR, Miller GM, Goldman MS et al (1995) Spinal dural arteriovenous fistulas: MR and myelographic findings. AJNR Am J Neuroradiol 16:2049–2057PubMed
10.
Zurück zum Zitat Willinsky RA, terBrugge K, Montanera W et al (1995) Posttreatment MR findings in spinal dural arteriovenous malformations. AJNR Am J Neuroradiol 16:2063–2071PubMed Willinsky RA, terBrugge K, Montanera W et al (1995) Posttreatment MR findings in spinal dural arteriovenous malformations. AJNR Am J Neuroradiol 16:2063–2071PubMed
11.
Zurück zum Zitat Bowen BC, Fraser K, Kochan JP et al (1995) Spinal dural arteriovenous fistulas: evaluation with MR angiography. AJNR Am J Neuroradiol 16:2029–2043PubMed Bowen BC, Fraser K, Kochan JP et al (1995) Spinal dural arteriovenous fistulas: evaluation with MR angiography. AJNR Am J Neuroradiol 16:2029–2043PubMed
12.
Zurück zum Zitat Binkert CA, Kollias SS, Valavanis A (1999) Spinal cord vascular disease: characterization with fast three-dimensional contrast-enhanced MR angiography. AJNR Am J Neuroradiol 20:1785–1793PubMed Binkert CA, Kollias SS, Valavanis A (1999) Spinal cord vascular disease: characterization with fast three-dimensional contrast-enhanced MR angiography. AJNR Am J Neuroradiol 20:1785–1793PubMed
13.
Zurück zum Zitat Farb RI, Kim JK, Willinsky RA et al (2002) Spinal dural arteriovenous fistula localization with a technique of first-pass gadolinium-enhanced MR angiography: initial experience. Radiology 222:843–850PubMedCrossRef Farb RI, Kim JK, Willinsky RA et al (2002) Spinal dural arteriovenous fistula localization with a technique of first-pass gadolinium-enhanced MR angiography: initial experience. Radiology 222:843–850PubMedCrossRef
14.
Zurück zum Zitat Saraf-Lavi E, Bowen BC, Quencer RM et al (2002) Detection of spinal dural arteriovenous fistulae with MR imaging and contrast-enhanced MR angiography: sensitivity, specificity, and prediction of vertebral level. AJNR Am J Neuroradiol 23:858–867PubMed Saraf-Lavi E, Bowen BC, Quencer RM et al (2002) Detection of spinal dural arteriovenous fistulae with MR imaging and contrast-enhanced MR angiography: sensitivity, specificity, and prediction of vertebral level. AJNR Am J Neuroradiol 23:858–867PubMed
15.
Zurück zum Zitat Luetmer PH, Lane JI, Gilbertson JR et al (2005) Preangiographic evaluation of spinal dural arteriovenous fistulas with elliptic centric contrast-enhanced MR Angiography and effect on radiation dose and volume of iodinated contrast material. AJNR Am J Neuroradiol 26:711–718PubMed Luetmer PH, Lane JI, Gilbertson JR et al (2005) Preangiographic evaluation of spinal dural arteriovenous fistulas with elliptic centric contrast-enhanced MR Angiography and effect on radiation dose and volume of iodinated contrast material. AJNR Am J Neuroradiol 26:711–718PubMed
16.
Zurück zum Zitat Krings T, Lasjaunias PL, Hans FJ et al (2007) Imaging in spinal vascular disease. Neuroimaging Clin N Am 17:57–72PubMedCrossRef Krings T, Lasjaunias PL, Hans FJ et al (2007) Imaging in spinal vascular disease. Neuroimaging Clin N Am 17:57–72PubMedCrossRef
17.
Zurück zum Zitat Mull M, Nijenhuis RJ, Backes WH et al (2007) Value and limitations of contrast-enhanced MR angiography in spinal arteriovenous malformations and dural arteriovenous fistulas. AJNR Am J Neuroradiol 28:1249–1258PubMedCrossRef Mull M, Nijenhuis RJ, Backes WH et al (2007) Value and limitations of contrast-enhanced MR angiography in spinal arteriovenous malformations and dural arteriovenous fistulas. AJNR Am J Neuroradiol 28:1249–1258PubMedCrossRef
18.
Zurück zum Zitat Yamaguchi S, Nagayama T, Eguchi K et al (2010) Accuracy and pitfalls of multidetector-row computed tomography in detecting spinal dural arteriovenous fistulas. J Neurosurg Spine 12:243–248PubMedCrossRef Yamaguchi S, Nagayama T, Eguchi K et al (2010) Accuracy and pitfalls of multidetector-row computed tomography in detecting spinal dural arteriovenous fistulas. J Neurosurg Spine 12:243–248PubMedCrossRef
19.
Zurück zum Zitat Zampakis P, Santosh C, Taylor W et al (2006) The role of non-invasive computed tomography in patients with suspected dural fistulas with spinal drainage. Neurosurgery 58:686–694, discussion 686–694PubMedCrossRef Zampakis P, Santosh C, Taylor W et al (2006) The role of non-invasive computed tomography in patients with suspected dural fistulas with spinal drainage. Neurosurgery 58:686–694, discussion 686–694PubMedCrossRef
20.
Zurück zum Zitat Si-jia G, Meng-wei Z, Xi-ping L et al (2009) The clinical application studies of CT spinal angiography with 64-detector row spiral CT in diagnosing spinal vascular malformations. Eur J Radiol 71:22–28PubMedCrossRef Si-jia G, Meng-wei Z, Xi-ping L et al (2009) The clinical application studies of CT spinal angiography with 64-detector row spiral CT in diagnosing spinal vascular malformations. Eur J Radiol 71:22–28PubMedCrossRef
21.
Zurück zum Zitat Backes WH, Nijenhuis RJ (2008) Advances in spinal cord MR angiography. AJNR Am J Neuroradiol 29:619–631PubMedCrossRef Backes WH, Nijenhuis RJ (2008) Advances in spinal cord MR angiography. AJNR Am J Neuroradiol 29:619–631PubMedCrossRef
22.
Zurück zum Zitat Willinsky R, Lasjaunias P, terBrugge K et al (1990) Angiography in the investigation of spinal dural arteriovenous fistula A protocol with application of the venous phase. Neuroradiology 32:114–116PubMedCrossRef Willinsky R, Lasjaunias P, terBrugge K et al (1990) Angiography in the investigation of spinal dural arteriovenous fistula A protocol with application of the venous phase. Neuroradiology 32:114–116PubMedCrossRef
23.
Zurück zum Zitat Pattany PM, Saraf-Lavi E, Bowen BC (2003) MR angiography of the spine and spinal cord. Top Magn Reson Imaging 14:444–460PubMedCrossRef Pattany PM, Saraf-Lavi E, Bowen BC (2003) MR angiography of the spine and spinal cord. Top Magn Reson Imaging 14:444–460PubMedCrossRef
24.
Zurück zum Zitat Provenzale JM, Tien RD, Felsberg GJ et al (1994) Spinal dural arteriovenous fistula: demonstration using phase contrast MRA. J Comput Assist Tomogr 18:811–814PubMedCrossRef Provenzale JM, Tien RD, Felsberg GJ et al (1994) Spinal dural arteriovenous fistula: demonstration using phase contrast MRA. J Comput Assist Tomogr 18:811–814PubMedCrossRef
25.
Zurück zum Zitat Soher BJ, Dale BM, Merkle EM (2007) A review of MR physics: 3T versus 1.5T. Magn Reson Imaging Clin N Am 15:277–290, vPubMedCrossRef Soher BJ, Dale BM, Merkle EM (2007) A review of MR physics: 3T versus 1.5T. Magn Reson Imaging Clin N Am 15:277–290, vPubMedCrossRef
26.
Zurück zum Zitat Boeckh-Behrens T, Bitterling H, Schichor C et al (2010) Improved localization of spinal AV fistulas using contrast-enhanced MR angiography at 3T. Röfo 182:53–57PubMed Boeckh-Behrens T, Bitterling H, Schichor C et al (2010) Improved localization of spinal AV fistulas using contrast-enhanced MR angiography at 3T. Röfo 182:53–57PubMed
27.
Zurück zum Zitat Vargas MI, Nguyen D, Viallon M et al (2010) Dynamic MR angiography (MRA) of spinal vascular diseases at 3T. Eur Radiol 20:2491–2495PubMedCrossRef Vargas MI, Nguyen D, Viallon M et al (2010) Dynamic MR angiography (MRA) of spinal vascular diseases at 3T. Eur Radiol 20:2491–2495PubMedCrossRef
28.
Zurück zum Zitat Riccioli LA, Marliani AF, Ghedin P et al (2007) CE-MR Angiography at 3.0T magnetic field in the study of spinal dural arteriovenous fistula. Preliminary Results. Interv Neuroradiol 13:13–18PubMed Riccioli LA, Marliani AF, Ghedin P et al (2007) CE-MR Angiography at 3.0T magnetic field in the study of spinal dural arteriovenous fistula. Preliminary Results. Interv Neuroradiol 13:13–18PubMed
29.
Zurück zum Zitat Ali S, Cashen TA, Carroll TJ et al (2007) Time-resolved spinal MR angiography: initial clinical experience in the evaluation of spinal arteriovenous shunts. AJNR Am J Neuroradiol 28:1806–1810PubMedCrossRef Ali S, Cashen TA, Carroll TJ et al (2007) Time-resolved spinal MR angiography: initial clinical experience in the evaluation of spinal arteriovenous shunts. AJNR Am J Neuroradiol 28:1806–1810PubMedCrossRef
Metadaten
Titel
The accuracy and utility of contrast-enhanced MR angiography for localization of spinal dural arteriovenous fistulas: the Toronto experience
verfasst von
Arjen Lindenholz
Karel G. TerBrugge
J. Marc C. van Dijk
Richard I. Farb
Publikationsdatum
01.11.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 11/2014
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3307-6

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