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Clinical and Translational Oncology
Erschienen in:

05.05.2024 | RESEARCH ARTICLE

The effect of hyperbaric oxygen therapy in head and neck cancer patients with radiation induced dysphagia—a systematic review

verfasst von: Bahareh Bakhshaie Philipsen, Malene Korsholm, Max Rohde, Irene Wessel, Lone Forner, Jørgen Johansen, Christian Godballe

Erschienen in: Clinical and Translational Oncology | Ausgabe 10/2024

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Abstract

Purpose

The aim of this systematic review was to assess the role of hyperbaric oxygen therapy  (HBOT) in patients with dysphagia after radiation therapy for head and neck cancer.

Method

A systematic search was conducted in the electronic databases Ovid MEDLINE, Ovid Embase, and Cochrane Central Register of Controlled Trials for relevant studies until March 14, 2023. No restriction on language or publication date. The criteria for inclusion: patients with HNC who had received both radiation therapy and HBOT as 1) a preventive treatment against swallowing difficulties, 2) to preserve swallowing function, or 3) to promote swallowing difficulties.

Results

We identified 1396 records. After removal of 31 duplicates, 1365 records were accessible for title and abstract screening. This yielded 53 studies for full text assessment. Six studies met the eligibility criteria and were included for qualitative analysis.

Conclusion

Evidence of HBOT benefits in patients with dysphagia after radiation therapy for head and neck cancer is inconsistent. Well-designed studies using validated outcome measures and long-term follow-up are warranted.
Literatur
1.
Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33.CrossRefPubMed
2.
Jakobsen KK, Grønhøj C, Jensen DH, Karnov KKS, Agander TK, Specht L, et al. Increasing incidence and survival of head and neck cancers in Denmark: a nation-wide study from 1980 to 2014. Acta Oncol. 2018;57(9):1143–51.CrossRefPubMed
3.
Mortensen HR, Jensen K, Aksglæde K, Behrens M, Grau C. Late dysphagia after IMRT for head and neck cancer and correlation with dose-volume parameters. Radiother Oncol. 2013;107(3):288–94.CrossRefPubMed
4.
Murphy BA, Gilbert J. Dysphagia in head and neck cancer patients treated with radiation: assessment, sequelae, and rehabilitation. Semin Radiat Oncol. 2009;19(1):35–42.CrossRefPubMed
5.
Nutting CM, Morden JP, Harrington KJ, Urbano TG, Bhide SA, Clark C, et al. Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncol. 2011;12(2):127–36.CrossRefPubMedPubMedCentral
6.
Saksø M, Andersen E, Bentzen J, Andersen M, Johansen J, Primdahl H, et al. A prospective, multicenter DAHANCA study of hyperfractionated, accelerated radiotherapy for head and neck squamous cell carcinoma. Acta Oncol. 2019;58(10):1495–501.CrossRefPubMed
7.
Raber-Durlacher JE, Brennan MT, Verdonck-de Leeuw IM, Gibson RJ, Eilers JG, Waltimo T, et al. Swallowing dysfunction in cancer patients. Support Care Cancer. 2012;20(3):433–43.CrossRefPubMed
8.
Mortensen HR, Overgaard J, Jensen K, Specht L, Overgaard M, Johansen J, et al. Factors associated with acute and late dysphagia in the DAHANCA 6 & 7 randomized trial with accelerated radiotherapy for head and neck cancer. Acta Oncol. 2013;52(7):1535–42.CrossRefPubMed
9.
Clarke RE, Tenorio LM, Hussey JR, Toklu AS, Cone DL, Hinojosa JG, et al. Hyperbaric oxygen treatment of chronic refractory radiation proctitis: a randomized and controlled double-blind crossover trial with long-term follow-up. Int J Radiat Oncol Biol Phys. 2008;72(1):134–43.CrossRefPubMed
10.
11.
Gill AL, Bell CN. Hyperbaric oxygen: its uses, mechanisms of action and outcomes. QJM. 2004;97(7):385–95.CrossRefPubMed
12.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.CrossRefPubMedPubMedCentral
13.
Teguh DN, Levendag PC, Noever I, Voet P, van der Est H, van Rooij P, et al. Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a randomized trial in oropharyngeal and nasopharyngeal cancer. Int J Radiat Oncol Biol Phys. 2009;75(3):711–6.CrossRefPubMed
14.
Gerlach NL, Barkhuysen R, Kaanders JH, Janssens GO, Sterk W, Merkx MA. The effect of hyperbaric oxygen therapy on quality of life in oral and oropharyngeal cancer patients treated with radiotherapy. Int J Oral Maxillofac Surg. 2008;37(3):255–9.CrossRefPubMed
15.
Tahir AR, Westhuyzen J, Dass J, Collins MK, Webb R, Hewitt S, et al. Hyperbaric oxygen therapy for chronic radiation-induced tissue injuries: Australasia’s largest study. Asia Pac J Clin Oncol. 2015;11(1):68–77.CrossRefPubMed
16.
Bui QC, Lieber M, Withers HR, Corson K, van Rijnsoever M, Elsaleh H. The efficacy of hyperbaric oxygen therapy in the treatment of radiation-induced late side effects. Int J Radiat Oncol Biol Phys. 2004;60(3):871–8.CrossRefPubMed
17.
Narozny W, Sicko Z, Kot J, Stankiewicz C, Przewozny T, Kuczkowski J. Hyperbaric oxygen therapy in the treatment of complications of irradiation in head and neck area. Undersea Hyperb Med. 2005;32(2):103–10.PubMed
18.
Ferguson BJ, Hudson WR, Farmer JC Jr. Hyperbaric oxygen therapy for laryngeal radionecrosis. Ann Otol Rhinol Laryngol. 1987;96(1 Pt 1):1–6.CrossRefPubMed
19.
Feldmeier JJ. Hyperbaric oxygen for delayed radiation injuries. Undersea Hyperb Med. 2004;31(1):133–45.PubMed
20.
Mortensen HR, Overgaard J, Specht L, Overgaard M, Johansen J, Evensen JF, et al. Prevalence and peak incidence of acute and late normal tissue morbidity in the DAHANCA 6&7 randomised trial with accelerated radiotherapy for head and neck cancer. Radiother Oncol. 2012;103(1):69–75.CrossRefPubMed
21.
Tribius S, Sommer J, Prosch C, Bajrovic A, Muenscher A, Blessmann M, et al. Xerostomia after radiotherapy. what matters–mean total dose or dose to each parotid gland? Strahlenther Onkol. 2013;189(3):216–22.CrossRefPubMed
22.
Pinna R, Campus G, Cumbo E, Mura I, Milia E. Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage. Ther Clin Risk Manag. 2015;11:171–88.CrossRefPubMedPubMedCentral
23.
Forner L, Hyldegaard O, von Brockdorff AS, Specht L, Andersen E, Jansen EC, et al. Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce xerostomia in previously irradiated head and neck cancer patients? a Pilot Study. Oral Oncol. 2011;47(6):546–51.CrossRefPubMed
24.
Cankar K, Finderle Z, Jan J. The effect of hyperbaric oxygenation on postradiation xerostomia and saliva in patients with head and neck tumours. Caries Res. 2011;45(2):136–41.CrossRefPubMed
25.
Fox NF, Xiao C, Sood AJ, Lovelace TL, Nguyen SA, Sharma A, et al. Hyperbaric oxygen therapy for the treatment of radiation-induced xerostomia: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120(1):22–8.CrossRefPubMed
26.
Plafki C, Peters P, Almeling M, Welslau W, Busch R. Complications and side effects of hyperbaric oxygen therapy. Aviat Space Environ Med. 2000;71(2):119–24.PubMed
27.
Hutcheson KA, Barrow MP, Lisec A, Barringer DA, Gries K, Lewin JS. What is a clinically relevant difference in MDADI scores between groups of head and neck cancer patients? Laryngoscope. 2016;126(5):1108–13.CrossRefPubMed
28.
Brady S, Donzelli J. The modified barium swallow and the functional endoscopic evaluation of swallowing. Otolaryngol Clin North Am. 2013;46(6):1009–22.CrossRefPubMed
Metadaten
Titel
The effect of hyperbaric oxygen therapy in head and neck cancer patients with radiation induced dysphagia—a systematic review
verfasst von
Bahareh Bakhshaie Philipsen
Malene Korsholm
Max Rohde
Irene Wessel
Lone Forner
Jørgen Johansen
Christian Godballe
Publikationsdatum
05.05.2024
Verlag
Springer International Publishing
Erschienen in
Clinical and Translational Oncology / Ausgabe 10/2024
Print ISSN: 1699-048X
Elektronische ISSN: 1699-3055
DOI
https://doi.org/10.1007/s12094-024-03449-w

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