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Comparative Clinical Pathology

Erschienen in:

01.10.2011 | Original Article

The effects of vitamin C on vitamin K-related clotting factors

verfasst von: Ameneh Khoshvaghti, S. Nazifi, B. Akbarpour, S. M. Razavi

Erschienen in: Comparative Clinical Pathology | Ausgabe 5/2011

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Abstract

The aim of this study was to assess the effects of vitamin C on vitamin K-related clotting factors II, VII, IX and X. Sixty female Wistar rats with a mean weight of 180 ± 20 g were selected, and after a 5-day adaptation period, control blood samples were taken under anaesthesia. The animals were randomly separated into two equal groups: one group received only warfarin for 30 days while the other group received both warfarin and vitamin C. Blood samples were taken at days 15 and 30 to measure vitamin K-related clotting factors, prothrombin time (PT) and activated partial thromboplastin time (APTT). The results showed that the combined administration of vitamin C and warfarin leads to increased coagulation factors II, VII, IX and X and decreased PT and APTT.

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Titel: The effects of vitamin C on vitamin K-related clotting factors
verfasst von: Ameneh Khoshvaghti
S. Nazifi
B. Akbarpour
S. M. Razavi
Publikationsdatum: 01.10.2011
Verlag: Springer-Verlag
Erschienen in: Comparative Clinical Pathology / Ausgabe 5/2011
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-010-1028-z

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

The effects of vitamin C on vitamin K-related clotting factors

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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