Skip to main content
Erschienen in: Journal of Assisted Reproduction and Genetics 11/2017

24.08.2017 | Reproductive Physiology and Disease

The relationship between fat and progesterone, estradiol, and chorionic gonadotropin levels in Quebec cow’s milk

verfasst von: A. R. Gilman, W. Buckett, W. Y. Son, J. Lefebvre, A. M. Mahfoudh, M. H. Dahan

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 11/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The majority of milk in industrialized countries is obtained from pregnant cows, which contains increased levels of estrogen and progesterone compared to non-pregnant cows. The aim of this study was to quantify the amount of hormones present in milk with different fat content because previous studies on humans have shown potential effects of increased milk consumption on serum and urine hormone levels as well as on sperm parameters. However, it is unclear whether consumption of milk at the currently recommended levels would lead to systemic effects.

Methods

Samples of cow’s milk of varying fat concentrations (0, 1, 2, 3.25, 10, and 35%) were analyzed via competitive ELISA assays.

Results

Progesterone concentrations were significantly correlated to increasing fat content of milk (r = 0.8251, p = 0.04).

Conclusions

Research on conditions in which additional progesterone may have an effect on human health should consider inclusion of limitation of milk intake and its effects. Further studies are needed to determine the concentration of progesterone in milk of different fat content in other regions and countries and to quantify the potential pathophysiologic role.
Literatur
1.
Zurück zum Zitat Haimov-Kochman R, Shore LS, Laufer N. The milk we drink, food for thought. Fertil Steril. 2016;106(6):1310–1.CrossRefPubMed Haimov-Kochman R, Shore LS, Laufer N. The milk we drink, food for thought. Fertil Steril. 2016;106(6):1310–1.CrossRefPubMed
2.
Zurück zum Zitat Malekinejad H, Scherpenisse P, Bergwerff AA. Naturally occurring estrogens in processed milk and in raw milk (from gestated cows). J Agric Food Chem. 2006;54(26):9785–91.CrossRefPubMed Malekinejad H, Scherpenisse P, Bergwerff AA. Naturally occurring estrogens in processed milk and in raw milk (from gestated cows). J Agric Food Chem. 2006;54(26):9785–91.CrossRefPubMed
3.
Zurück zum Zitat Goyon A, Cai JZ, Kraehenbuehl K, Hartmann C, Shao B, Mottier P. Determination of steroid hormones in bovine milk by LC-MS/MS and their levels in Swiss Holstein cow milk. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33(5):804–16.CrossRefPubMed Goyon A, Cai JZ, Kraehenbuehl K, Hartmann C, Shao B, Mottier P. Determination of steroid hormones in bovine milk by LC-MS/MS and their levels in Swiss Holstein cow milk. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016;33(5):804–16.CrossRefPubMed
4.
Zurück zum Zitat Committee for Veterinary Medicinal Products. Progesterone: summary report. The European Agency for the Evaluation of Medicinal Products, Evaluation and Inspections. December 1999. Available at: http://www.ema.europa.eu/docs/en_GB /document_library/Maximum_Residue_Limits_-_Report/2011/07/WC500108427. Pdf. Accessed 6 March 2017. Committee for Veterinary Medicinal Products. Progesterone: summary report. The European Agency for the Evaluation of Medicinal Products, Evaluation and Inspections. December 1999. Available at: http://​www.​ema.​europa.​eu/​docs/​en_​GB /document_library/Maximum_Residue_Limits_-_Report/2011/07/WC500108427. Pdf. Accessed 6 March 2017.
5.
Zurück zum Zitat Maruyama K, Oshima T, Ohyama K. Exposure to exogenous estrogen through intake of commercial milk produced from pregnant cows. Pediatr Int. 2010;52(1):33–8.CrossRefPubMed Maruyama K, Oshima T, Ohyama K. Exposure to exogenous estrogen through intake of commercial milk produced from pregnant cows. Pediatr Int. 2010;52(1):33–8.CrossRefPubMed
6.
Zurück zum Zitat Afeiche M, Williams PL, Mendiola J, Gaskins AJ, Jorgensen N, Swan SH, et al. Dairy food intake in relation to semen quality and reproductive hormone levels among physically active young men. Hum Reprod. 2013;28(8):2265–75.CrossRefPubMedPubMedCentral Afeiche M, Williams PL, Mendiola J, Gaskins AJ, Jorgensen N, Swan SH, et al. Dairy food intake in relation to semen quality and reproductive hormone levels among physically active young men. Hum Reprod. 2013;28(8):2265–75.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Macrina AL, Ott TL, Roberts RF, Kensinger RS. Estrone and estrone sulfate concentrations in milk and milk fractions. J Acad Nutr Diet. 2012;112(7):1088–93.CrossRefPubMed Macrina AL, Ott TL, Roberts RF, Kensinger RS. Estrone and estrone sulfate concentrations in milk and milk fractions. J Acad Nutr Diet. 2012;112(7):1088–93.CrossRefPubMed
Metadaten
Titel
The relationship between fat and progesterone, estradiol, and chorionic gonadotropin levels in Quebec cow’s milk
verfasst von
A. R. Gilman
W. Buckett
W. Y. Son
J. Lefebvre
A. M. Mahfoudh
M. H. Dahan
Publikationsdatum
24.08.2017
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 11/2017
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-017-1025-0

Weitere Artikel der Ausgabe 11/2017

Journal of Assisted Reproduction and Genetics 11/2017 Zur Ausgabe

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.