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World Journal of Urology

Erschienen in:

01.06.2011 | Topic Paper

The role of randomized controlled trials in evidence-based urology

verfasst von: Luke T. Lavallée, Dean Fergusson, Rodney H. Breau

Erschienen in: World Journal of Urology | Ausgabe 3/2011

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Abstract

Purpose

To review the current and future role of randomized controlled trials (RCTs) in urology.

Methods

A review of the urological literature was performed to assess the current role of RCTs in urology. These findings were put in context of current practice, and methodologic limitations of observational study design were discussed.

Results

Several RCTs have improved treatment of urology patients. However, overall, few studies in the urologic literature convey high-level evidence. RCTs represent the only study design that can assess causality, thus are the only means to significantly advance knowledge about therapy and improve patient care. Increased incidence and improved quality of RCTs may be achieved through education, community outreach, and better access to research infrastructure.

Conclusions

RCTs have significantly improved urologic practice. RCTs are superior to observational studies because of decreased risk of bias and confounding. To further advance clinical practice, clinical trials must play a predominant role and should be embraced by the urology community.

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Titel: The role of randomized controlled trials in evidence-based urology
verfasst von: Luke T. Lavallée
Dean Fergusson
Rodney H. Breau
Publikationsdatum: 01.06.2011
Verlag: Springer-Verlag
Erschienen in: World Journal of Urology / Ausgabe 3/2011
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-011-0646-7

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The role of randomized controlled trials in evidence-based urology

Abstract

Purpose

Methods

Results

Conclusions

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