Erschienen in:
01.06.2003 | Brief Report
Two Unusual Cases of Diffuse Acrodermatitis Chronica Atrophicans Seronegative for Lyme Borreliosis
verfasst von:
T. G. Berger, C. Schoerner, H. Schell, M. Simon Jr, G. Schuler, M. Röllinghoff, A. Gessner
Erschienen in:
European Journal of Clinical Microbiology & Infectious Diseases
|
Ausgabe 6/2003
Einloggen, um Zugang zu erhalten
Excerpt
Acrodermatitis chronica atrophicans (ACA) is a late cutaneous manifestation of Lyme borreliosis [
1]. In this stage of disease, serum IgG-antibodies against
Borrelia burgdorferi have been detected in practically all patients examined so far [
2,
3,
4]. Reported here are the cases of two patients with unusual manifestations of ACA. The histopathological pattern was consistent with ACA in both cases, but repeated serological examinations for antibodies against
Borrelia burgdorferi were negative. The diagnosis was only confirmed in both cases by the detection of
Borrelia burgdorferi-specific DNA using nested PCR and subsequent sequencing of the products. …