Unraveling the enigma of genetics and phenotypes in ARDS

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Zurück zum Zitat Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA (2002) Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 346(17):1281–1286. https://doi.org/10.1056/NEJMoa012835CrossRefPubMed Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA (2002) Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 346(17):1281–1286. https://​doi.​org/​10.​1056/​NEJMoa012835CrossRefPubMed

Zurück zum Zitat Misset B, Piagnerelli M, Hoste E, Dardenne N, Grimaldi D, Michaux I, De Waele E, Dumoulin A, Jorens PG, van der Hauwaert E, Vallot F, Lamote S, Swinnen W, De Schryver N, Fraipont V, de Mey N, Dauby N, Layios N, Mesland JB, Meyfroidt G, Moutschen M, Compernolle V, Gothot A, Desmecht D, Taveira da Silva Pereira MI, Garigliany M, Najdovski T, Bertrand A, Donneau AF, Laterre PF (2023) Convalescent plasma for COVID-19-INDUCED ARDS in mechanically ventilated patients. N Engl J Med 389(17):1590–1600. https://doi.org/10.1056/NEJMoa2209502CrossRefPubMedPubMedCentral Misset B, Piagnerelli M, Hoste E, Dardenne N, Grimaldi D, Michaux I, De Waele E, Dumoulin A, Jorens PG, van der Hauwaert E, Vallot F, Lamote S, Swinnen W, De Schryver N, Fraipont V, de Mey N, Dauby N, Layios N, Mesland JB, Meyfroidt G, Moutschen M, Compernolle V, Gothot A, Desmecht D, Taveira da Silva Pereira MI, Garigliany M, Najdovski T, Bertrand A, Donneau AF, Laterre PF (2023) Convalescent plasma for COVID-19-INDUCED ARDS in mechanically ventilated patients. N Engl J Med 389(17):1590–1600. https://​doi.​org/​10.​1056/​NEJMoa2209502CrossRefPubMedPubMedCentral

Zurück zum Zitat Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, Mc Auley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A, for the LUNG SAFE Investigators and the ESICM Trials Group (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315(8):788–800. https://doi.org/10.1001/jama.2016.0291CrossRefPubMed Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, Mc Auley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A, for the LUNG SAFE Investigators and the ESICM Trials Group (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315(8):788–800. https://​doi.​org/​10.​1001/​jama.​2016.​0291CrossRefPubMed

Zurück zum Zitat Matthay MA, Arabi Y, Arroliga AC, Bernard G, Bersten AD, Brochard LJ, Calfee CS, Combes A, Daniel BM, Ferguson ND, Gong MN, Gotts JE, Herridge MS, Laffey JG, Liu KD, Machado FR, Martin TR, McAuley DF, Mercat A, Moss M, Mularski RA, Pesenti A, Qiu H, Ramakrishnan N, Ranieri VM, Riviello ED, Rubin E, Slutsky AS, Thompson BT, Twagirumugabe T, Ware LB, Wick KD (2023) A new global definition of acute respiratory distress syndrome. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.202303-0558WSCrossRefPubMedPubMedCentral Matthay MA, Arabi Y, Arroliga AC, Bernard G, Bersten AD, Brochard LJ, Calfee CS, Combes A, Daniel BM, Ferguson ND, Gong MN, Gotts JE, Herridge MS, Laffey JG, Liu KD, Machado FR, Martin TR, McAuley DF, Mercat A, Moss M, Mularski RA, Pesenti A, Qiu H, Ramakrishnan N, Ranieri VM, Riviello ED, Rubin E, Slutsky AS, Thompson BT, Twagirumugabe T, Ware LB, Wick KD (2023) A new global definition of acute respiratory distress syndrome. Am J Respir Crit Care Med. https://​doi.​org/​10.​1164/​rccm.​202303-0558WSCrossRefPubMedPubMedCentral

Zurück zum Zitat De Haro C, Martin-Loeches I, Torrents E, Artigas A (2013) Acute respiratory distress syndrome: prevention and early recognition. Ann Intensive Care 3:11. https://doi.org/10.1186/2110-5820-3-11CrossRefPubMedPubMedCentral De Haro C, Martin-Loeches I, Torrents E, Artigas A (2013) Acute respiratory distress syndrome: prevention and early recognition. Ann Intensive Care 3:11. https://​doi.​org/​10.​1186/​2110-5820-3-11CrossRefPubMedPubMedCentral

Zurück zum Zitat Gajic O, Dabbagh O, Park PK, Adesanya A, Chang SY, Hou P, Anderson H, Hoth JJ, Mikkelsen ME, Gentile NT, Gong MN, Talmor D, Bajwa E, Watkins TR, Festic E, Yilmaz M, Iscimen R, Kaufman DA, Esper AM, Sadikot R, Douglas I, Sevransky J, Malinchoc M, on behalf of the U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS) (2011) Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med 183:462–470. https://doi.org/10.1164/rccm.201004-0549OCCrossRefPubMed Gajic O, Dabbagh O, Park PK, Adesanya A, Chang SY, Hou P, Anderson H, Hoth JJ, Mikkelsen ME, Gentile NT, Gong MN, Talmor D, Bajwa E, Watkins TR, Festic E, Yilmaz M, Iscimen R, Kaufman DA, Esper AM, Sadikot R, Douglas I, Sevransky J, Malinchoc M, on behalf of the U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS) (2011) Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med 183:462–470. https://​doi.​org/​10.​1164/​rccm.​201004-0549OCCrossRefPubMed

Zurück zum Zitat Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS (2013) Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med 1(187):736–742. https://doi.org/10.1164/rccm.201208-1460OCCrossRef Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS (2013) Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med 1(187):736–742. https://​doi.​org/​10.​1164/​rccm.​201208-1460OCCrossRef

Zurück zum Zitat Jabaudon M, Berthelin P, Pranal T, Roszyk L, Godet T, Faure JS, Chabanne R, Eisenmann N, Lautrette A, Belville C, Blondonnet R, Cayot S, Gillart T, Pascal J, Skrzypczak Y, Souweine B, Blanchon L, Sapin V, Pereira B, Constantin JM (2018) Receptor for advanced glycation end-products and ARDS prediction: a multicenter observational study. Sci Rep 8:2603. https://doi.org/10.1038/s41598-018-20994-xCrossRefPubMedPubMedCentral Jabaudon M, Berthelin P, Pranal T, Roszyk L, Godet T, Faure JS, Chabanne R, Eisenmann N, Lautrette A, Belville C, Blondonnet R, Cayot S, Gillart T, Pascal J, Skrzypczak Y, Souweine B, Blanchon L, Sapin V, Pereira B, Constantin JM (2018) Receptor for advanced glycation end-products and ARDS prediction: a multicenter observational study. Sci Rep 8:2603. https://​doi.​org/​10.​1038/​s41598-018-20994-xCrossRefPubMedPubMedCentral

Zurück zum Zitat Suarez-Pajes E, Tosco-Herrera E, Ramirez-Falcon M, Gonzalez-Barbuzano S, Heranndez-Beeftinik T, Guilen-Guio B, Villar J, Flores C (2023) Genetic determinants of the acute respiratory distress syndrome. J Clin Med 12(11):3713. https://doi.org/10.3390/jcm12112713CrossRefPubMedPubMedCentral Suarez-Pajes E, Tosco-Herrera E, Ramirez-Falcon M, Gonzalez-Barbuzano S, Heranndez-Beeftinik T, Guilen-Guio B, Villar J, Flores C (2023) Genetic determinants of the acute respiratory distress syndrome. J Clin Med 12(11):3713. https://​doi.​org/​10.​3390/​jcm12112713CrossRefPubMedPubMedCentral

Zurück zum Zitat Cao S, Li H, Xin J, Jin Z, Zhang Z, Li J, Zhu Y, Su L, Huang P, Jiang L, Du M, Christiani DC (2023) Identification of genetic profile and biomarkers involved in acute respiratory distress syndrome. Intensive Care Med. https://doi.org/10.1007/s00134-023-07248-9CrossRefPubMed Cao S, Li H, Xin J, Jin Z, Zhang Z, Li J, Zhu Y, Su L, Huang P, Jiang L, Du M, Christiani DC (2023) Identification of genetic profile and biomarkers involved in acute respiratory distress syndrome. Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-023-07248-9CrossRefPubMed