Skip to main content
Erschienen in: Abdominal Radiology 6/2020

11.12.2018 | Special Section: Endometriosis

What abdominal radiologists should know about extragenital endometriosis-associated neuropathy

verfasst von: Jucélio Pereira Moura Filho, Renata Vidal Leão, Natally Horvat, Paulo Victor Partezani Helito, Denise Tokechi Amaral, Publio Cesar Cavalcanti Viana, Isabel Curcio Felix Louza, Marcelo Bordalo-Rodrigues

Erschienen in: Abdominal Radiology | Ausgabe 6/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The aim of this study is to provide an overview of endometriosis-associated neuropathy and to review main anatomical concepts of intrapelvic peripheral nerves.

Methods

In this pictorial essay, we review the anatomy of pelvic nerves and imaging features of endometriosis-associated neuropathy. We also evaluate clinical findings, imaging features, and outcome of seven patients with endometriosis-associated neuropathy.

Results

Nerve involvement by endometriosis is rare and may manifest with neurological symptoms, including pain, muscle weakness, bowel and bladder incontinence, and paraplegia. The neural involvement may be isolated or caused by a direct extension of a deep infiltrating endometriosis of the pelvic structure. Magnetic resonance imaging (MRI) is a reliable imaging modality for detecting neural involvement of endometriosis. On MRI, the main imaging features are retractile fibrous tissue and endometriomas. The signal intensity of the endometriotic tissue may vary depending on the age of the hemorrhage and the proportion of endometrial cells and stroma. Early diagnosis and treatment may avoid permanent neural damage.

Conclusion

Considering that patients with endometriosis usually undergo pelvic MRI, which is generally reported by a non-musculoskeletal-trained radiologist, abdominal radiologists need to be familiar with the pelvic nerve anatomy and the possible patterns of presentation of neural endometriosis. Early diagnosis may obviate permanent nerve damage and MRI is a reliable tool for the diagnosis.
Literatur
1.
Zurück zum Zitat Giudice LC, Kao LC (2004) Endometriosis. Lancet 364(9447):1789–1799CrossRef Giudice LC, Kao LC (2004) Endometriosis. Lancet 364(9447):1789–1799CrossRef
2.
Zurück zum Zitat Morassutto C, Monasta L, Ricci G, Barbone F, Ronfani L (2016) Incidence and estimated prevalence of endometriosis and adenomyosis in Northeast Italy: a data linkage study. PLoS ONE 11(4):e0154227CrossRef Morassutto C, Monasta L, Ricci G, Barbone F, Ronfani L (2016) Incidence and estimated prevalence of endometriosis and adenomyosis in Northeast Italy: a data linkage study. PLoS ONE 11(4):e0154227CrossRef
3.
Zurück zum Zitat Gordts S, Koninckx P, Brosens I (2017) Pathogenesis of deep endometriosis. Fertil Steril. 108(6):872–885CrossRef Gordts S, Koninckx P, Brosens I (2017) Pathogenesis of deep endometriosis. Fertil Steril. 108(6):872–885CrossRef
4.
Zurück zum Zitat Coutinho A, Bittencourt LK, Pires CE, Junqueira F, Lima CM, Coutinho E, et al. (2011) MR imaging in deep pelvic endometriosis: a pictorial essay. Radiographics. 31(2):549–567CrossRef Coutinho A, Bittencourt LK, Pires CE, Junqueira F, Lima CM, Coutinho E, et al. (2011) MR imaging in deep pelvic endometriosis: a pictorial essay. Radiographics. 31(2):549–567CrossRef
5.
Zurück zum Zitat Parasar P, Ozcan P, Terry KL (2017) Endometriosis: epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 6(1):34–41CrossRef Parasar P, Ozcan P, Terry KL (2017) Endometriosis: epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 6(1):34–41CrossRef
6.
Zurück zum Zitat Ceccaroni M, Clarizia R, Roviglione G, Bruni F, Ruffo G, Peters I, et al. (2010) Deep rectal and parametrial infiltrating endometriosis with monolateral pudendal nerve involvement: case report and laparoscopic nerve-sparing approach. Eur J Obstet Gynecol Reprod Biol. 153(2):227–229CrossRef Ceccaroni M, Clarizia R, Roviglione G, Bruni F, Ruffo G, Peters I, et al. (2010) Deep rectal and parametrial infiltrating endometriosis with monolateral pudendal nerve involvement: case report and laparoscopic nerve-sparing approach. Eur J Obstet Gynecol Reprod Biol. 153(2):227–229CrossRef
7.
Zurück zum Zitat Descamps P, Cottier JP, Barre I, Rosset P, Laffont J, Lansac J, et al. (1995) Endometriosis of the sciatic nerve: case report demonstrating the value of MR imaging. Eur J Obstet Gynecol Reprod Biol. 58(2):199–202CrossRef Descamps P, Cottier JP, Barre I, Rosset P, Laffont J, Lansac J, et al. (1995) Endometriosis of the sciatic nerve: case report demonstrating the value of MR imaging. Eur J Obstet Gynecol Reprod Biol. 58(2):199–202CrossRef
8.
Zurück zum Zitat Jeswani S, Drazin D, Shirzadi A, Fan X, Johnson JP (2011) Endometriosis in the lumbar plexus mimicking a nerve sheath tumor. World J Oncol. 2(6):314–318PubMedPubMedCentral Jeswani S, Drazin D, Shirzadi A, Fan X, Johnson JP (2011) Endometriosis in the lumbar plexus mimicking a nerve sheath tumor. World J Oncol. 2(6):314–318PubMedPubMedCentral
9.
Zurück zum Zitat Motamedi M, Mousavinia F, Naser Moghadasi A, Talebpoor M, Hajimirzabeigi A (2015) Endometriosis of the lumbosacral plexus: report of a case with foot drop and chronic pelvic pain. Acta Neurol Belg. 115(4):851–852CrossRef Motamedi M, Mousavinia F, Naser Moghadasi A, Talebpoor M, Hajimirzabeigi A (2015) Endometriosis of the lumbosacral plexus: report of a case with foot drop and chronic pelvic pain. Acta Neurol Belg. 115(4):851–852CrossRef
10.
Zurück zum Zitat Possover M, Chiantera V (2007) Isolated infiltrative endometriosis of the sciatic nerve: a report of three patients. Fertil Steril. 87(2):417.e17–417.e19CrossRef Possover M, Chiantera V (2007) Isolated infiltrative endometriosis of the sciatic nerve: a report of three patients. Fertil Steril. 87(2):417.e17–417.e19CrossRef
11.
Zurück zum Zitat Possover M, Baekelandt J, Flaskamp C, Li D, Chiantera V (2007) Laparoscopic neurolysis of the sacral plexus and the sciatic nerve for extensive endometriosis of the pelvic wall. Minim Invasive Neurosurg. 50(1):33–36CrossRef Possover M, Baekelandt J, Flaskamp C, Li D, Chiantera V (2007) Laparoscopic neurolysis of the sacral plexus and the sciatic nerve for extensive endometriosis of the pelvic wall. Minim Invasive Neurosurg. 50(1):33–36CrossRef
12.
Zurück zum Zitat Reddy S, Porter D, Patton JT, Al-Nafussi A, Beggs I (2007) Endometriosis of the superior gluteal nerve. Skeletal Radiol. 36(9):879–883CrossRef Reddy S, Porter D, Patton JT, Al-Nafussi A, Beggs I (2007) Endometriosis of the superior gluteal nerve. Skeletal Radiol. 36(9):879–883CrossRef
13.
Zurück zum Zitat Siquara de Sousa AC, Capek S, Howe BM, Jentoft ME, Amrami KK, Spinner RJ (2015) Magnetic resonance imaging evidence for perineural spread of endometriosis to the lumbosacral plexus: report of 2 cases. Neurosurg Focus. 39(3):E15CrossRef Siquara de Sousa AC, Capek S, Howe BM, Jentoft ME, Amrami KK, Spinner RJ (2015) Magnetic resonance imaging evidence for perineural spread of endometriosis to the lumbosacral plexus: report of 2 cases. Neurosurg Focus. 39(3):E15CrossRef
14.
Zurück zum Zitat Vercellini P, Chapron C, Fedele L, Frontino G, Zaina B, Crosignani PG (2003) Evidence for asymmetric distribution of sciatic nerve endometriosis. Obstet Gynecol. 102(2):383–387PubMed Vercellini P, Chapron C, Fedele L, Frontino G, Zaina B, Crosignani PG (2003) Evidence for asymmetric distribution of sciatic nerve endometriosis. Obstet Gynecol. 102(2):383–387PubMed
15.
Zurück zum Zitat Siquara De Sousa AC, Capek S, Amrami KK, Spinner RJ (2015) Neural involvement in endometriosis: review of anatomic distribution and mechanisms. Clin Anat. 28(8):1029–1038CrossRef Siquara De Sousa AC, Capek S, Amrami KK, Spinner RJ (2015) Neural involvement in endometriosis: review of anatomic distribution and mechanisms. Clin Anat. 28(8):1029–1038CrossRef
16.
Zurück zum Zitat Gebarski KS, Gebarski SS, Glazer GM, Samuels BI, Francis IR (1986) The lumbosacral plexus: anatomic-radiologic-pathologic correlation using CT. Radiographics. 6(3):401–425CrossRef Gebarski KS, Gebarski SS, Glazer GM, Samuels BI, Francis IR (1986) The lumbosacral plexus: anatomic-radiologic-pathologic correlation using CT. Radiographics. 6(3):401–425CrossRef
17.
Zurück zum Zitat Rv L, Dt A, Pvp H, Lcz R, Mb R (2017) Magnetic resonance imaging of hip neuropathies beyond the sciatica: a practical approach. Curr Radiol Rep. 5:36CrossRef Rv L, Dt A, Pvp H, Lcz R, Mb R (2017) Magnetic resonance imaging of hip neuropathies beyond the sciatica: a practical approach. Curr Radiol Rep. 5:36CrossRef
18.
Zurück zum Zitat Neufeld EA, Shen PY, Nidecker AE, Runner G, Bateni C, Tse G, et al. (2015) MR imaging of the lumbosacral plexus: a review of techniques and pathologies. J Neuroimaging. 25(5):691–703CrossRef Neufeld EA, Shen PY, Nidecker AE, Runner G, Bateni C, Tse G, et al. (2015) MR imaging of the lumbosacral plexus: a review of techniques and pathologies. J Neuroimaging. 25(5):691–703CrossRef
19.
Zurück zum Zitat Chhabra A, Faridian-Aragh N (2012) High-resolution 3-T MR neurography of femoral neuropathy. AJR Am J Roentgenol. 198(1):3–10CrossRef Chhabra A, Faridian-Aragh N (2012) High-resolution 3-T MR neurography of femoral neuropathy. AJR Am J Roentgenol. 198(1):3–10CrossRef
20.
Zurück zum Zitat Martinoli C, Miguel-Perez M, Padua L, Gandolfo N, Zicca A, Tagliafico A (2013) Imaging of neuropathies about the hip. Eur J Radiol. 82(1):17–26CrossRef Martinoli C, Miguel-Perez M, Padua L, Gandolfo N, Zicca A, Tagliafico A (2013) Imaging of neuropathies about the hip. Eur J Radiol. 82(1):17–26CrossRef
21.
Zurück zum Zitat Mannan K, Altaf F, Maniar S, Tirabosco R, Sinisi M, Carlstedt T (2008) Cyclical sciatica: endometriosis of the sciatic nerve. J Bone Joint Surg Br. 90(1):98–101CrossRef Mannan K, Altaf F, Maniar S, Tirabosco R, Sinisi M, Carlstedt T (2008) Cyclical sciatica: endometriosis of the sciatic nerve. J Bone Joint Surg Br. 90(1):98–101CrossRef
22.
Zurück zum Zitat Schlicke CP (1946) Ectopic endometrial tissue in the thigh. J Am Med Assoc. 132:445CrossRef Schlicke CP (1946) Ectopic endometrial tissue in the thigh. J Am Med Assoc. 132:445CrossRef
23.
Zurück zum Zitat Papapietro N, Gulino G, Zobel BB, Di Martino A, Denaro V (2002) Cyclic sciatica related to an extrapelvic endometriosis of the sciatic nerve: new concepts in surgical therapy. J Spinal Disord Tech. 15(5):436–439CrossRef Papapietro N, Gulino G, Zobel BB, Di Martino A, Denaro V (2002) Cyclic sciatica related to an extrapelvic endometriosis of the sciatic nerve: new concepts in surgical therapy. J Spinal Disord Tech. 15(5):436–439CrossRef
24.
Zurück zum Zitat Zhang Z, Song L, Meng Q, Li Z, Pan B, Yang Z, et al. (2009) Morphological analysis in patients with sciatica: a magnetic resonance imaging study using three-dimensional high-resolution diffusion-weighted magnetic resonance neurography techniques. Spine (Phila Pa 1976). 34(7):E245–E250CrossRef Zhang Z, Song L, Meng Q, Li Z, Pan B, Yang Z, et al. (2009) Morphological analysis in patients with sciatica: a magnetic resonance imaging study using three-dimensional high-resolution diffusion-weighted magnetic resonance neurography techniques. Spine (Phila Pa 1976). 34(7):E245–E250CrossRef
25.
Zurück zum Zitat Yekeler E, Kumbasar B, Tunaci A, Barman A, Bengisu E, Yavuz E, et al. (2004) Cyclic sciatica caused by infiltrative endometriosis: mRI findings. Skeletal Radiol. 33(3):165–168CrossRef Yekeler E, Kumbasar B, Tunaci A, Barman A, Bengisu E, Yavuz E, et al. (2004) Cyclic sciatica caused by infiltrative endometriosis: mRI findings. Skeletal Radiol. 33(3):165–168CrossRef
26.
Zurück zum Zitat Cottier JP, Descamps P, Sonier CB, Rosset P (1995) Sciatic endometriosis: MR evaluation. AJNR Am J Neuroradiol. 16(7):1399–1401PubMed Cottier JP, Descamps P, Sonier CB, Rosset P (1995) Sciatic endometriosis: MR evaluation. AJNR Am J Neuroradiol. 16(7):1399–1401PubMed
27.
Zurück zum Zitat Gougoutas CA, Siegelman ES, Hunt J, Outwater EK (2000) Pelvic endometriosis: various manifestations and MR imaging findings. AJR Am J Roentgenol. 175(2):353–358CrossRef Gougoutas CA, Siegelman ES, Hunt J, Outwater EK (2000) Pelvic endometriosis: various manifestations and MR imaging findings. AJR Am J Roentgenol. 175(2):353–358CrossRef
28.
Zurück zum Zitat Siegelman ES, Oliver ER (2012) MR imaging of endometriosis: ten imaging pearls. Radiographics. 32(6):1675–1691CrossRef Siegelman ES, Oliver ER (2012) MR imaging of endometriosis: ten imaging pearls. Radiographics. 32(6):1675–1691CrossRef
29.
Zurück zum Zitat Choudhary S, Fasih N, Papadatos D, Surabhi VR (2009) Unusual imaging appearances of endometriosis. AJR Am J Roentgenol. 192(6):1632–1644CrossRef Choudhary S, Fasih N, Papadatos D, Surabhi VR (2009) Unusual imaging appearances of endometriosis. AJR Am J Roentgenol. 192(6):1632–1644CrossRef
Metadaten
Titel
What abdominal radiologists should know about extragenital endometriosis-associated neuropathy
verfasst von
Jucélio Pereira Moura Filho
Renata Vidal Leão
Natally Horvat
Paulo Victor Partezani Helito
Denise Tokechi Amaral
Publio Cesar Cavalcanti Viana
Isabel Curcio Felix Louza
Marcelo Bordalo-Rodrigues
Publikationsdatum
11.12.2018
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 6/2020
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-018-1864-x

Weitere Artikel der Ausgabe 6/2020

Abdominal Radiology 6/2020 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

13.04.2024 Klinik aktuell Kongressbericht

Die Teilnehmer eines Forums beim DGIM-Kongress waren sich einig: Fehler in der Medizin sind häufig in ungeeigneten Prozessen und mangelnder Kommunikation begründet. Gespräche mit Patienten und im Team können helfen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.