Skip to main content
Erschienen in: Skeletal Radiology 3/2023

09.07.2022 | Review Article

Whole body imaging in musculoskeletal oncology: when, why, and how

verfasst von: Joao R. T. Vicentini, Miriam A. Bredella

Erschienen in: Skeletal Radiology | Ausgabe 3/2023

Einloggen, um Zugang zu erhalten

Abstract

The use of whole-body imaging has become increasingly popular in oncology due to the possibility of evaluating total tumor burden with a single imaging study. This is particularly helpful in cases of widespread disease where dedicated regional imaging would make the evaluation more expensive, time consuming, and prone to more risks. Different techniques can be used, including whole-body MRI, whole-body CT, and PET-CT. Common indications include surveillance of cancer predisposing syndromes, evaluation of osseous metastases and clonal plasma cell disorders such as multiple myeloma, and evaluation of soft tissue lesions, including peripheral nerve sheath tumors. This review focuses on advanced whole-body imaging techniques and their main uses in musculoskeletal oncology.
Literatur
1.
Zurück zum Zitat Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos M-V, Lonial S, et al. International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders. Lancet Oncol. 2019;20:e302–12.CrossRef Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos M-V, Lonial S, et al. International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders. Lancet Oncol. 2019;20:e302–12.CrossRef
2.
Zurück zum Zitat Davila D, Antoniou A, Chaudhry MA. Evaluation of osseous metastasis in bone scintigraphy. Semin Nucl Med. 2015;45:3–15.CrossRef Davila D, Antoniou A, Chaudhry MA. Evaluation of osseous metastasis in bone scintigraphy. Semin Nucl Med. 2015;45:3–15.CrossRef
3.
Zurück zum Zitat Vicentini JRT, Bredella MA. Role of FDG PET in the staging of multiple myeloma. Skeletal Radiol. 2022;51:31–41.CrossRef Vicentini JRT, Bredella MA. Role of FDG PET in the staging of multiple myeloma. Skeletal Radiol. 2022;51:31–41.CrossRef
4.
Zurück zum Zitat Behzadi AH, Raza SI, Carrino JA, Kosmas C, Gholamrezanezhad A, Basques K, et al. Applications of PET/CT and PET/MR imaging in primary bone malignancies. PET Clin. 2018;13:623–34.CrossRef Behzadi AH, Raza SI, Carrino JA, Kosmas C, Gholamrezanezhad A, Basques K, et al. Applications of PET/CT and PET/MR imaging in primary bone malignancies. PET Clin. 2018;13:623–34.CrossRef
5.
Zurück zum Zitat Morone M, Bali MA, Tunariu N, Messiou C, Blackledge M, Grazioli L, et al. Whole-body MRI: current applications in oncology. Am J Roentgenol. 2017;209:W336–49.CrossRef Morone M, Bali MA, Tunariu N, Messiou C, Blackledge M, Grazioli L, et al. Whole-body MRI: current applications in oncology. Am J Roentgenol. 2017;209:W336–49.CrossRef
6.
Zurück zum Zitat Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, et al. Whole-body imaging of multiple myeloma: diagnostic criteria. Radiographics. 2019;39:1077–97.CrossRef Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, et al. Whole-body imaging of multiple myeloma: diagnostic criteria. Radiographics. 2019;39:1077–97.CrossRef
7.
Zurück zum Zitat Winfield JM, Blackledge MD, Tunariu N, Koh D-M, Messiou C. Whole-body MRI: a practical guide for imaging patients with malignant bone disease. Clin Radiol. 2021;76:715–27.CrossRef Winfield JM, Blackledge MD, Tunariu N, Koh D-M, Messiou C. Whole-body MRI: a practical guide for imaging patients with malignant bone disease. Clin Radiol. 2021;76:715–27.CrossRef
8.
Zurück zum Zitat Gottumukkala RV, Gee MS, Hampilos PJ, Greer M-LC. Current and emerging roles of whole-body MRI in evaluation of pediatric cancer patients. RadioGraphics. 2019;39:516–34.CrossRef Gottumukkala RV, Gee MS, Hampilos PJ, Greer M-LC. Current and emerging roles of whole-body MRI in evaluation of pediatric cancer patients. RadioGraphics. 2019;39:516–34.CrossRef
9.
Zurück zum Zitat Ahlawat S, Fayad LM, Khan MS, Bredella MA, Harris GJ, Evans DG, et al. Current whole-body MRI applications in the neurofibromatoses: NF1, NF2, and schwannomatosis. Neurology. 2016;87:S31–9.CrossRef Ahlawat S, Fayad LM, Khan MS, Bredella MA, Harris GJ, Evans DG, et al. Current whole-body MRI applications in the neurofibromatoses: NF1, NF2, and schwannomatosis. Neurology. 2016;87:S31–9.CrossRef
10.
Zurück zum Zitat Fayad LM, Jacobs MA, Wang X, Carrino JA, Bluemke DA. Musculoskeletal tumors: how to use anatomic, functional, and metabolic MR techniques. Radiology. 2012;265:340–56.CrossRef Fayad LM, Jacobs MA, Wang X, Carrino JA, Bluemke DA. Musculoskeletal tumors: how to use anatomic, functional, and metabolic MR techniques. Radiology. 2012;265:340–56.CrossRef
11.
Zurück zum Zitat Messiou C, Hillengass J, Delorme S, Lecouvet FE, Moulopoulos LA, Collins DJ, et al. Guidelines for acquisition, interpretation, and reporting of whole-body MRI in myeloma: Myeloma Response Assessment and Diagnosis System (MY-RADS). Radiology. 2019;291:5–13.CrossRef Messiou C, Hillengass J, Delorme S, Lecouvet FE, Moulopoulos LA, Collins DJ, et al. Guidelines for acquisition, interpretation, and reporting of whole-body MRI in myeloma: Myeloma Response Assessment and Diagnosis System (MY-RADS). Radiology. 2019;291:5–13.CrossRef
12.
Zurück zum Zitat Padhani AR, Koh D-M, Collins DJ. Whole-body diffusion-weighted MR imaging in cancer: current status and research directions. Radiology. 2011;261:700–18.CrossRef Padhani AR, Koh D-M, Collins DJ. Whole-body diffusion-weighted MR imaging in cancer: current status and research directions. Radiology. 2011;261:700–18.CrossRef
13.
Zurück zum Zitat Del Vescovo R, Frauenfelder G, Giurazza F, Piccolo CL, Cazzato RL, Grasso RF, et al. Role of whole-body diffusion-weighted MRI in detecting bone metastasis. Radiol Med (Torino). 2014;119:758–66.CrossRef Del Vescovo R, Frauenfelder G, Giurazza F, Piccolo CL, Cazzato RL, Grasso RF, et al. Role of whole-body diffusion-weighted MRI in detecting bone metastasis. Radiol Med (Torino). 2014;119:758–66.CrossRef
14.
Zurück zum Zitat Dutoit JC, Verstraete KL. Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma. Skeletal Radiol. 2017;46:733–50.CrossRef Dutoit JC, Verstraete KL. Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma. Skeletal Radiol. 2017;46:733–50.CrossRef
15.
Zurück zum Zitat Nakanishi K, Kobayashi M, Nakaguchi K, Kyakuno M, Hashimoto N, Onishi H, et al. Whole-body MRI for detecting metastatic bone tumor: diagnostic value of diffusion-weighted images. Magn Reson Med Sci. 2007;6:147–55.CrossRef Nakanishi K, Kobayashi M, Nakaguchi K, Kyakuno M, Hashimoto N, Onishi H, et al. Whole-body MRI for detecting metastatic bone tumor: diagnostic value of diffusion-weighted images. Magn Reson Med Sci. 2007;6:147–55.CrossRef
16.
Zurück zum Zitat Takenaka D, Ohno Y, Matsumoto K, Aoyama N, Onishi Y, Koyama H, et al. Detection of bone metastases in non-small cell lung cancer patients: comparison of whole-body diffusion-weighted imaging (DWI), whole-body MR imaging without and with DWI, whole-body FDG-PET/CT, and bone scintigraphy. J Magn Reson Imaging. 2009;30:298–308.CrossRef Takenaka D, Ohno Y, Matsumoto K, Aoyama N, Onishi Y, Koyama H, et al. Detection of bone metastases in non-small cell lung cancer patients: comparison of whole-body diffusion-weighted imaging (DWI), whole-body MR imaging without and with DWI, whole-body FDG-PET/CT, and bone scintigraphy. J Magn Reson Imaging. 2009;30:298–308.CrossRef
17.
Zurück zum Zitat Pawlyn C, Fowkes L, Otero S, Jones JR, Boyd KD, Davies FE, et al. Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma? Leukemia. 2016;30:1446–8.CrossRef Pawlyn C, Fowkes L, Otero S, Jones JR, Boyd KD, Davies FE, et al. Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma? Leukemia. 2016;30:1446–8.CrossRef
18.
Zurück zum Zitat Larbi A, Omoumi P, Pasoglou V, Michoux N, Triqueneaux P, Tombal B, et al. Whole-body MRI to assess bone involvement in prostate cancer and multiple myeloma: comparison of the diagnostic accuracies of the T1, short tau inversion recovery (STIR), and high b-values diffusion-weighted imaging (DWI) sequences. Eur Radiol. 2019;29:4503–13.CrossRef Larbi A, Omoumi P, Pasoglou V, Michoux N, Triqueneaux P, Tombal B, et al. Whole-body MRI to assess bone involvement in prostate cancer and multiple myeloma: comparison of the diagnostic accuracies of the T1, short tau inversion recovery (STIR), and high b-values diffusion-weighted imaging (DWI) sequences. Eur Radiol. 2019;29:4503–13.CrossRef
19.
Zurück zum Zitat Costelloe CM, Madewell JE, Kundra V, Harrell RK, Bassett RL, Ma J. Conspicuity of bone metastases on fast Dixon-based multisequence whole-body MRI: clinical utility per sequence. Magn Reson Imaging. 2013;31:669–75.CrossRef Costelloe CM, Madewell JE, Kundra V, Harrell RK, Bassett RL, Ma J. Conspicuity of bone metastases on fast Dixon-based multisequence whole-body MRI: clinical utility per sequence. Magn Reson Imaging. 2013;31:669–75.CrossRef
20.
Zurück zum Zitat Bray TJP, Singh S, Latifoltojar A, Rajesparan K, Rahman F, Narayanan P, et al. Diagnostic utility of whole body Dixon MRI in multiple myeloma: a multi-reader study Jiang Q, editor. PLOS ONE. 2017;12:e0180562.CrossRef Bray TJP, Singh S, Latifoltojar A, Rajesparan K, Rahman F, Narayanan P, et al. Diagnostic utility of whole body Dixon MRI in multiple myeloma: a multi-reader study Jiang Q, editor. PLOS ONE. 2017;12:e0180562.CrossRef
21.
Zurück zum Zitat Padhani AR, Lecouvet FE, Tunariu N, Koh D-M, De Keyzer F, Collins DJ, et al. METastasis Reporting and Data System for Prostate Cancer: practical guidelines for acquisition, interpretation, and reporting of whole-body magnetic resonance imaging-based evaluations of multiorgan involvement in advanced prostate cancer. Eur Urol. 2017;71:81–92.CrossRef Padhani AR, Lecouvet FE, Tunariu N, Koh D-M, De Keyzer F, Collins DJ, et al. METastasis Reporting and Data System for Prostate Cancer: practical guidelines for acquisition, interpretation, and reporting of whole-body magnetic resonance imaging-based evaluations of multiorgan involvement in advanced prostate cancer. Eur Urol. 2017;71:81–92.CrossRef
22.
Zurück zum Zitat Consul N, Amini B, Ibarra-Rovira JJ, Blair KJ, Moseley TW, Taher A, et al. Li-Fraumeni syndrome and whole-body MRI screening: screening guidelines, imaging features, and impact on patient management. Am J Roentgenol. 2021;216:252–63.CrossRef Consul N, Amini B, Ibarra-Rovira JJ, Blair KJ, Moseley TW, Taher A, et al. Li-Fraumeni syndrome and whole-body MRI screening: screening guidelines, imaging features, and impact on patient management. Am J Roentgenol. 2021;216:252–63.CrossRef
23.
Zurück zum Zitat Villani A, Shore A, Wasserman JD, Stephens D, Kim RH, Druker H, et al. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. Lancet Oncol. 2016;17:1295–305.CrossRef Villani A, Shore A, Wasserman JD, Stephens D, Kim RH, Druker H, et al. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. Lancet Oncol. 2016;17:1295–305.CrossRef
24.
Zurück zum Zitat Kleinerman RA. Radiation-sensitive genetically susceptible pediatric sub-populations. Pediatr Radiol. 2009;39:27–31.CrossRef Kleinerman RA. Radiation-sensitive genetically susceptible pediatric sub-populations. Pediatr Radiol. 2009;39:27–31.CrossRef
25.
Zurück zum Zitat Jiang W, Rixiati Y, Zhao B, Li Y, Tang C, Liu J. Incidence, prevalence, and outcomes of systemic malignancy with bone metastases. J Orthop Surg. 2020;28:230949902091598.CrossRef Jiang W, Rixiati Y, Zhao B, Li Y, Tang C, Liu J. Incidence, prevalence, and outcomes of systemic malignancy with bone metastases. J Orthop Surg. 2020;28:230949902091598.CrossRef
26.
Zurück zum Zitat Daldrup-Link HE, Franzius C, Link TM, Laukamp D, Sciuk J, Jürgens H, et al. Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. Am J Roentgenol. 2001;177:229–36.CrossRef Daldrup-Link HE, Franzius C, Link TM, Laukamp D, Sciuk J, Jürgens H, et al. Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. Am J Roentgenol. 2001;177:229–36.CrossRef
27.
Zurück zum Zitat Nakanishi K, Kobayashi M, Takahashi S, Nakata S, Kyakuno M, Nakaguchi K, et al. Whole body MRI for detecting metastatic bone tumor: comparison with bone scintigrams. Magn Reson Med Sci. 2005;4:11–7.CrossRef Nakanishi K, Kobayashi M, Takahashi S, Nakata S, Kyakuno M, Nakaguchi K, et al. Whole body MRI for detecting metastatic bone tumor: comparison with bone scintigrams. Magn Reson Med Sci. 2005;4:11–7.CrossRef
28.
Zurück zum Zitat Sohaib SA, Cook G, Allen SD, Hughes M, Eisen T, Gore M. Comparison of whole-body MRI and bone scintigraphy in the detection of bone metastases in renal cancer. Br J Radiol. 2009;82:632–9.CrossRef Sohaib SA, Cook G, Allen SD, Hughes M, Eisen T, Gore M. Comparison of whole-body MRI and bone scintigraphy in the detection of bone metastases in renal cancer. Br J Radiol. 2009;82:632–9.CrossRef
29.
Zurück zum Zitat Chen B, Wei P, Macapinlac HA, Lu Y. Comparison of 18F-fluciclovine PET/CT and 99mTc-MDP bone scan in detection of bone metastasis in prostate cancer. Nucl Med Commun. 2019;40:940–6.CrossRef Chen B, Wei P, Macapinlac HA, Lu Y. Comparison of 18F-fluciclovine PET/CT and 99mTc-MDP bone scan in detection of bone metastasis in prostate cancer. Nucl Med Commun. 2019;40:940–6.CrossRef
30.
Zurück zum Zitat Kosmin M, Padhani AR, Gogbashian A, Woolf D, Ah-See M-L, Ostler P, et al. Comparison of whole-body MRI, CT, and bone scintigraphy for response evaluation of cancer therapeutics in metastatic breast cancer to bone. Radiology. 2020;297:622–9.CrossRef Kosmin M, Padhani AR, Gogbashian A, Woolf D, Ah-See M-L, Ostler P, et al. Comparison of whole-body MRI, CT, and bone scintigraphy for response evaluation of cancer therapeutics in metastatic breast cancer to bone. Radiology. 2020;297:622–9.CrossRef
31.
Zurück zum Zitat Perez-Lopez R, Tunariu N, Padhani AR, Oyen WJG, Fanti S, Vargas HA, et al. Imaging diagnosis and follow-up of advanced prostate cancer: clinical perspectives and state of the art. Radiology. 2019;292:273–86.CrossRef Perez-Lopez R, Tunariu N, Padhani AR, Oyen WJG, Fanti S, Vargas HA, et al. Imaging diagnosis and follow-up of advanced prostate cancer: clinical perspectives and state of the art. Radiology. 2019;292:273–86.CrossRef
32.
Zurück zum Zitat Wu Q, Yang R, Zhou F, Hu Y. Comparison of whole-body MRI and skeletal scintigraphy for detection of bone metastatic tumors: a meta-analysis. Surg Oncol. 2013;22:261–6.CrossRef Wu Q, Yang R, Zhou F, Hu Y. Comparison of whole-body MRI and skeletal scintigraphy for detection of bone metastatic tumors: a meta-analysis. Surg Oncol. 2013;22:261–6.CrossRef
33.
Zurück zum Zitat Wu L-M, Gu H-Y, Zheng J, Xu X, Lin L-H, Deng X, et al. Diagnostic value of whole-body magnetic resonance imaging for bone metastases: a systematic review and meta-analysis. J Magn Reson Imaging. 2011;34:128–35.CrossRef Wu L-M, Gu H-Y, Zheng J, Xu X, Lin L-H, Deng X, et al. Diagnostic value of whole-body magnetic resonance imaging for bone metastases: a systematic review and meta-analysis. J Magn Reson Imaging. 2011;34:128–35.CrossRef
34.
Zurück zum Zitat Papageorgiou I, Dvorak J, Cosma I, Pfeil A, Teichgraeber U, Malich A. Whole-body MRI: a powerful alternative to bone scan for bone marrow staging without radiation and gadolinium enhancer. Clin Transl Oncol. 2020;22:1321–8.CrossRef Papageorgiou I, Dvorak J, Cosma I, Pfeil A, Teichgraeber U, Malich A. Whole-body MRI: a powerful alternative to bone scan for bone marrow staging without radiation and gadolinium enhancer. Clin Transl Oncol. 2020;22:1321–8.CrossRef
35.
Zurück zum Zitat Lee K, Park HY, Kim KW, Lee AJ, Yoon MA, Chae EJ, et al. Advances in whole body MRI for musculoskeletal imaging: diffusion-weighted imaging. J Clin Orthop Trauma. 2019;10:680–6.CrossRef Lee K, Park HY, Kim KW, Lee AJ, Yoon MA, Chae EJ, et al. Advances in whole body MRI for musculoskeletal imaging: diffusion-weighted imaging. J Clin Orthop Trauma. 2019;10:680–6.CrossRef
36.
Zurück zum Zitat Pearce T, Philip S, Brown J, Koh DM, Burn PR. Bone metastases from prostate, breast and multiple myeloma: differences in lesion conspicuity at short-tau inversion recovery and diffusion-weighted MRI. Br J Radiol. 2012;85:1102–6.CrossRef Pearce T, Philip S, Brown J, Koh DM, Burn PR. Bone metastases from prostate, breast and multiple myeloma: differences in lesion conspicuity at short-tau inversion recovery and diffusion-weighted MRI. Br J Radiol. 2012;85:1102–6.CrossRef
37.
Zurück zum Zitat Rajkumar SV. Updated diagnostic criteria and staging system for multiple myeloma. Am Soc Clin Oncol Educ Book. 2016;35:e418-423.CrossRef Rajkumar SV. Updated diagnostic criteria and staging system for multiple myeloma. Am Soc Clin Oncol Educ Book. 2016;35:e418-423.CrossRef
38.
Zurück zum Zitat Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos M-V, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15:e538-548.CrossRef Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos M-V, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15:e538-548.CrossRef
39.
Zurück zum Zitat Zamagni E, Nanni C, Patriarca F, Englaro E, Castellucci P, Geatti O, et al. A prospective comparison of 18F-fluorodeoxyglucose positron emission tomography-computed tomography, magnetic resonance imaging and whole-body planar radiographs in the assessment of bone disease in newly diagnosed multiple myeloma. Haematologica. 2007;92:50–5.CrossRef Zamagni E, Nanni C, Patriarca F, Englaro E, Castellucci P, Geatti O, et al. A prospective comparison of 18F-fluorodeoxyglucose positron emission tomography-computed tomography, magnetic resonance imaging and whole-body planar radiographs in the assessment of bone disease in newly diagnosed multiple myeloma. Haematologica. 2007;92:50–5.CrossRef
40.
Zurück zum Zitat Chen J, Li C, Tian Y, Xiao Q, Deng M, Hu H, et al. Comparison of whole-body DWI and 18 F-FDG PET/CT for detecting intramedullary and extramedullary lesions in multiple myeloma. Am J Roentgenol. 2019;213:514–23.CrossRef Chen J, Li C, Tian Y, Xiao Q, Deng M, Hu H, et al. Comparison of whole-body DWI and 18 F-FDG PET/CT for detecting intramedullary and extramedullary lesions in multiple myeloma. Am J Roentgenol. 2019;213:514–23.CrossRef
41.
Zurück zum Zitat Wang D, Huo Y, Chen S, Wang H, Ding Y, Zhu X, et al. Whole-body MRI versus 18F-FDG PET/CT for pretherapeutic assessment and staging of lymphoma: a meta-analysis. OncoTargets Ther. 2018;11:3597–608.CrossRef Wang D, Huo Y, Chen S, Wang H, Ding Y, Zhu X, et al. Whole-body MRI versus 18F-FDG PET/CT for pretherapeutic assessment and staging of lymphoma: a meta-analysis. OncoTargets Ther. 2018;11:3597–608.CrossRef
42.
Zurück zum Zitat Albano D, Bruno A, Patti C, Micci G, Midiri M, Tarella C, et al. Whole-body magnetic resonance imaging (WB-MRI) in lymphoma: state of the art. Hematol Oncol. 2020;38:12–21.CrossRef Albano D, Bruno A, Patti C, Micci G, Midiri M, Tarella C, et al. Whole-body magnetic resonance imaging (WB-MRI) in lymphoma: state of the art. Hematol Oncol. 2020;38:12–21.CrossRef
43.
Zurück zum Zitat Albano D, Patti C, Lagalla R, Midiri M, Galia M. Whole-body MRI, FDG-PET/CT, and bone marrow biopsy, for the assessment of bone marrow involvement in patients with newly diagnosed lymphoma: whole-body MRI in lymphoma marrow involvement. J Magn Reson Imaging. 2017;45:1082–9.CrossRef Albano D, Patti C, Lagalla R, Midiri M, Galia M. Whole-body MRI, FDG-PET/CT, and bone marrow biopsy, for the assessment of bone marrow involvement in patients with newly diagnosed lymphoma: whole-body MRI in lymphoma marrow involvement. J Magn Reson Imaging. 2017;45:1082–9.CrossRef
44.
Zurück zum Zitat Adams HJA, Kwee TC, Vermoolen MA, de Keizer B, de Klerk JMH, Adam JA, et al. Whole-body MRI for the detection of bone marrow involvement in lymphoma: prospective study in 116 patients and comparison with FDG-PET. Eur Radiol. 2013;23:2271–8.CrossRef Adams HJA, Kwee TC, Vermoolen MA, de Keizer B, de Klerk JMH, Adam JA, et al. Whole-body MRI for the detection of bone marrow involvement in lymphoma: prospective study in 116 patients and comparison with FDG-PET. Eur Radiol. 2013;23:2271–8.CrossRef
45.
Zurück zum Zitat Kharuzhyk S, Zhavrid E, Dziuban A, Sukolinskaja E, Kalenik O. Comparison of whole-body MRI with diffusion-weighted imaging and PET/CT in lymphoma staging. Eur Radiol. 2020;30:3915–23.CrossRef Kharuzhyk S, Zhavrid E, Dziuban A, Sukolinskaja E, Kalenik O. Comparison of whole-body MRI with diffusion-weighted imaging and PET/CT in lymphoma staging. Eur Radiol. 2020;30:3915–23.CrossRef
46.
Zurück zum Zitat Jurik AG, Jørgensen PH, Mortensen MM. Whole-body MRI in assessing malignant transformation in multiple hereditary exostoses and enchondromatosis: audit results and literature review. Skeletal Radiol. 2020;49:115–24.CrossRef Jurik AG, Jørgensen PH, Mortensen MM. Whole-body MRI in assessing malignant transformation in multiple hereditary exostoses and enchondromatosis: audit results and literature review. Skeletal Radiol. 2020;49:115–24.CrossRef
47.
Zurück zum Zitat Kim JR, Yoon HM, Jung AY, Cho YA, Seo JJ, Lee JS. Comparison of whole-body MRI, bone scan, and radiographic skeletal survey for lesion detection and risk stratification of Langerhans Cell Histiocytosis. Sci Rep. 2019;9:317.CrossRef Kim JR, Yoon HM, Jung AY, Cho YA, Seo JJ, Lee JS. Comparison of whole-body MRI, bone scan, and radiographic skeletal survey for lesion detection and risk stratification of Langerhans Cell Histiocytosis. Sci Rep. 2019;9:317.CrossRef
48.
Zurück zum Zitat Goo HW, Yang DH, Ra YS, Song JS, Im HJ, Seo JJ, et al. Whole-body MRI of Langerhans cell histiocytosis: comparison with radiography and bone scintigraphy. Pediatr Radiol. 2006;36:1019–31.CrossRef Goo HW, Yang DH, Ra YS, Song JS, Im HJ, Seo JJ, et al. Whole-body MRI of Langerhans cell histiocytosis: comparison with radiography and bone scintigraphy. Pediatr Radiol. 2006;36:1019–31.CrossRef
49.
Zurück zum Zitat Miettunen PM, Lafay-Cousin L, Guilcher GMT, Nettel-Aguirre A, Moorjani V. Widespread osteonecrosis in children with leukemia revealed by whole-body MRI. Clin Orthop. 2012;470:3587–95.CrossRef Miettunen PM, Lafay-Cousin L, Guilcher GMT, Nettel-Aguirre A, Moorjani V. Widespread osteonecrosis in children with leukemia revealed by whole-body MRI. Clin Orthop. 2012;470:3587–95.CrossRef
50.
Zurück zum Zitat Yoon HM, Kim JR, Jung AY, Cho YA, Im HJ, Lee JS. Whole body MR imaging: a useful imaging modality in the management of children with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2017;17:231–7.CrossRef Yoon HM, Kim JR, Jung AY, Cho YA, Im HJ, Lee JS. Whole body MR imaging: a useful imaging modality in the management of children with acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2017;17:231–7.CrossRef
51.
Zurück zum Zitat Cai W, Kassarjian A, Bredella MA, Harris GJ, Yoshida H, Mautner VF, et al. Tumor burden in patients with neurofibromatosis types 1 and 2 and schwannomatosis: determination on whole-body MR images. Radiology. 2009;250:665–73.CrossRef Cai W, Kassarjian A, Bredella MA, Harris GJ, Yoshida H, Mautner VF, et al. Tumor burden in patients with neurofibromatosis types 1 and 2 and schwannomatosis: determination on whole-body MR images. Radiology. 2009;250:665–73.CrossRef
52.
Zurück zum Zitat Ahlawat S, Blakeley JO, Langmead S, Belzberg AJ, Fayad LM. Current status and recommendations for imaging in neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. Skeletal Radiol. 2020;49:199–219.CrossRef Ahlawat S, Blakeley JO, Langmead S, Belzberg AJ, Fayad LM. Current status and recommendations for imaging in neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. Skeletal Radiol. 2020;49:199–219.CrossRef
53.
Zurück zum Zitat Plotkin SR, Bredella MA, Cai W, Kassarjian A, Harris GJ, Esparza S, et al. Quantitative assessment of whole-body tumor burden in adult patients with neurofibromatosis Herholz K, editor. PLoS ONE. 2012;7:e35711.CrossRef Plotkin SR, Bredella MA, Cai W, Kassarjian A, Harris GJ, Esparza S, et al. Quantitative assessment of whole-body tumor burden in adult patients with neurofibromatosis Herholz K, editor. PLoS ONE. 2012;7:e35711.CrossRef
54.
Zurück zum Zitat Cai W, Steinberg SM, Bredella MA, Basinsky G, Somarouthu B, Plotkin SR, et al. Volumetric MRI analysis of plexiform neurofibromas in neurofibromatosis type 1. Acad Radiol. 2018;25:144–52.CrossRef Cai W, Steinberg SM, Bredella MA, Basinsky G, Somarouthu B, Plotkin SR, et al. Volumetric MRI analysis of plexiform neurofibromas in neurofibromatosis type 1. Acad Radiol. 2018;25:144–52.CrossRef
55.
Zurück zum Zitat Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, et al. Activity of selumetinib in neurofibromatosis type 1–related plexiform neurofibromas. N Engl J Med. 2016;375:2550–60.CrossRef Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, et al. Activity of selumetinib in neurofibromatosis type 1–related plexiform neurofibromas. N Engl J Med. 2016;375:2550–60.CrossRef
56.
Zurück zum Zitat Weiss B, Widemann BC, Wolters P, Dombi E, Vinks A, Cantor A, et al. Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study. Neuro-Oncol. 2015;17:596–603.CrossRef Weiss B, Widemann BC, Wolters P, Dombi E, Vinks A, Cantor A, et al. Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study. Neuro-Oncol. 2015;17:596–603.CrossRef
57.
Zurück zum Zitat Demehri S, Belzberg A, Blakeley J, Fayad LM. Conventional and functional MR imaging of peripheral nerve sheath tumors: initial experience. Am J Neuroradiol. 2014;35:1615–20.CrossRef Demehri S, Belzberg A, Blakeley J, Fayad LM. Conventional and functional MR imaging of peripheral nerve sheath tumors: initial experience. Am J Neuroradiol. 2014;35:1615–20.CrossRef
58.
Zurück zum Zitat Derlin T, Tornquist K, Münster S, Apostolova I, Hagel C, Friedrich RE, et al. Comparative effectiveness of 18F-FDG PET/CT versus whole-body MRI for detection of malignant peripheral nerve sheath tumors in neurofibromatosis type 1. Clin Nucl Med. 2013;38:e19-25.CrossRef Derlin T, Tornquist K, Münster S, Apostolova I, Hagel C, Friedrich RE, et al. Comparative effectiveness of 18F-FDG PET/CT versus whole-body MRI for detection of malignant peripheral nerve sheath tumors in neurofibromatosis type 1. Clin Nucl Med. 2013;38:e19-25.CrossRef
59.
Zurück zum Zitat Moulopoulos LA, Koutoulidis V, Hillengass J, Zamagni E, Aquerreta JD, Roche CL, et al. Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group. Blood Cancer J. 2018;8:95.CrossRef Moulopoulos LA, Koutoulidis V, Hillengass J, Zamagni E, Aquerreta JD, Roche CL, et al. Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group. Blood Cancer J. 2018;8:95.CrossRef
60.
Zurück zum Zitat Simeone FJ, Harvey JP, Yee AJ, O’Donnell EK, Raje NS, Torriani M, et al. Value of low-dose whole-body CT in the management of patients with multiple myeloma and precursor states. Skeletal Radiol. 2019;48:773–9.CrossRef Simeone FJ, Harvey JP, Yee AJ, O’Donnell EK, Raje NS, Torriani M, et al. Value of low-dose whole-body CT in the management of patients with multiple myeloma and precursor states. Skeletal Radiol. 2019;48:773–9.CrossRef
61.
Zurück zum Zitat Hinge M, Andersen KT, Lund T, Jorgensen HB, Holdgaard PC, Ormstrup TE, et al. Baseline bone involvement in multiple myeloma - a prospective comparison of conventional X-ray, low-dose computed tomography, and 18flourodeoxyglucose positron emission tomography in previously untreated patients. Haematologica. 2016;101:e415–8.CrossRef Hinge M, Andersen KT, Lund T, Jorgensen HB, Holdgaard PC, Ormstrup TE, et al. Baseline bone involvement in multiple myeloma - a prospective comparison of conventional X-ray, low-dose computed tomography, and 18flourodeoxyglucose positron emission tomography in previously untreated patients. Haematologica. 2016;101:e415–8.CrossRef
62.
Zurück zum Zitat Kröpil P, Fenk R, Fritz LB, Blondin D, Kobbe G, Mödder U, et al. Comparison of whole-body 64-slice multidetector computed tomography and conventional radiography in staging of multiple myeloma. Eur Radiol. 2008;18:51–8.CrossRef Kröpil P, Fenk R, Fritz LB, Blondin D, Kobbe G, Mödder U, et al. Comparison of whole-body 64-slice multidetector computed tomography and conventional radiography in staging of multiple myeloma. Eur Radiol. 2008;18:51–8.CrossRef
63.
Zurück zum Zitat Hillengass J, Moulopoulos LA, Delorme S, Koutoulidis V, Mosebach J, Hielscher T, et al. Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group. Blood Cancer J. 2017;7:e599–e599.CrossRef Hillengass J, Moulopoulos LA, Delorme S, Koutoulidis V, Mosebach J, Hielscher T, et al. Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group. Blood Cancer J. 2017;7:e599–e599.CrossRef
64.
Zurück zum Zitat Kapoor V, McCook BM, Torok FS. An introduction to PET-CT imaging. Radiographics. 2004;24:523–43.CrossRef Kapoor V, McCook BM, Torok FS. An introduction to PET-CT imaging. Radiographics. 2004;24:523–43.CrossRef
65.
Zurück zum Zitat Boellaard R. Standards for PET image acquisition and quantitative data analysis. J Nucl Med Off Publ Soc Nucl Med. 2009;50(Suppl 1):11S-20S. Boellaard R. Standards for PET image acquisition and quantitative data analysis. J Nucl Med Off Publ Soc Nucl Med. 2009;50(Suppl 1):11S-20S.
66.
Zurück zum Zitat Buchbender C, Hartung-Knemeyer V, Forsting M, Antoch G, Heusner TA. Positron emission tomography (PET) attenuation correction artefacts in PET/CT and PET/MRI. Br J Radiol. 2013;86:20120570.CrossRef Buchbender C, Hartung-Knemeyer V, Forsting M, Antoch G, Heusner TA. Positron emission tomography (PET) attenuation correction artefacts in PET/CT and PET/MRI. Br J Radiol. 2013;86:20120570.CrossRef
67.
Zurück zum Zitat Breyer RJ, Mulligan ME, Smith SE, Line BR, Badros AZ. Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 2006;35:632–40.CrossRef Breyer RJ, Mulligan ME, Smith SE, Line BR, Badros AZ. Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 2006;35:632–40.CrossRef
68.
Zurück zum Zitat Sager S, Ergül N, Ciftci H, Cetin G, Güner Sİ, Cermik TF. The value of FDG PET/CT in the initial staging and bone marrow involvement of patients with multiple myeloma. Skeletal Radiol. 2011;40:843–7.CrossRef Sager S, Ergül N, Ciftci H, Cetin G, Güner Sİ, Cermik TF. The value of FDG PET/CT in the initial staging and bone marrow involvement of patients with multiple myeloma. Skeletal Radiol. 2011;40:843–7.CrossRef
69.
Zurück zum Zitat Moreau P, Attal M, Caillot D, Macro M, Karlin L, Garderet L, et al. Prospective evaluation of magnetic resonance imaging and [18 F]fluorodeoxyglucose positron emission tomography-computed tomography at diagnosis and before maintenance therapy in symptomatic patients with multiple myeloma included in the IFM/DFCI 2009 trial: results of the IMAJEM study. J Clin Oncol. 2017;35:2911–8.CrossRef Moreau P, Attal M, Caillot D, Macro M, Karlin L, Garderet L, et al. Prospective evaluation of magnetic resonance imaging and [18 F]fluorodeoxyglucose positron emission tomography-computed tomography at diagnosis and before maintenance therapy in symptomatic patients with multiple myeloma included in the IFM/DFCI 2009 trial: results of the IMAJEM study. J Clin Oncol. 2017;35:2911–8.CrossRef
70.
Zurück zum Zitat Patriarca F, Carobolante F, Zamagni E, Montefusco V, Bruno B, Englaro E, et al. The role of positron emission tomography with 18F-fluorodeoxyglucose integrated with computed tomography in the evaluation of patients with multiple myeloma undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant J Am Soc Blood Marrow Transplant. 2015;21:1068–73.CrossRef Patriarca F, Carobolante F, Zamagni E, Montefusco V, Bruno B, Englaro E, et al. The role of positron emission tomography with 18F-fluorodeoxyglucose integrated with computed tomography in the evaluation of patients with multiple myeloma undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant J Am Soc Blood Marrow Transplant. 2015;21:1068–73.CrossRef
71.
Zurück zum Zitat Stecco A, Buemi F, Iannessi A, Carriero A, Gallamini A. Current concepts in tumor imaging with whole-body MRI with diffusion imaging (WB-MRI-DWI) in multiple myeloma and lymphoma. Leuk Lymphoma. 2018;59:2546–56.CrossRef Stecco A, Buemi F, Iannessi A, Carriero A, Gallamini A. Current concepts in tumor imaging with whole-body MRI with diffusion imaging (WB-MRI-DWI) in multiple myeloma and lymphoma. Leuk Lymphoma. 2018;59:2546–56.CrossRef
72.
Zurück zum Zitat Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014;32:3059–67.CrossRef Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014;32:3059–67.CrossRef
73.
Zurück zum Zitat Berthet L, Cochet A, Kanoun S, Berriolo-Riedinger A, Humbert O, Toubeau M, et al. In newly diagnosed diffuse large B-cell lymphoma, determination of bone marrow involvement with 18 F-FDG PET/CT provides better diagnostic performance and prognostic stratification than does biopsy. J Nucl Med. 2013;54:1244–50.CrossRef Berthet L, Cochet A, Kanoun S, Berriolo-Riedinger A, Humbert O, Toubeau M, et al. In newly diagnosed diffuse large B-cell lymphoma, determination of bone marrow involvement with 18 F-FDG PET/CT provides better diagnostic performance and prognostic stratification than does biopsy. J Nucl Med. 2013;54:1244–50.CrossRef
74.
Zurück zum Zitat El-Galaly TC, d’Amore F, Mylam KJ, de Nully BP, Bøgsted M, Bukh A, et al. Routine bone marrow biopsy has little or no therapeutic consequence for positron emission tomography/computed tomography–staged treatment-naive patients with Hodgkin lymphoma. J Clin Oncol. 2012;30:4508–14.CrossRef El-Galaly TC, d’Amore F, Mylam KJ, de Nully BP, Bøgsted M, Bukh A, et al. Routine bone marrow biopsy has little or no therapeutic consequence for positron emission tomography/computed tomography–staged treatment-naive patients with Hodgkin lymphoma. J Clin Oncol. 2012;30:4508–14.CrossRef
75.
Zurück zum Zitat Khan AB, Barrington SF, Mikhaeel NG, Hunt AA, Cameron L, Morris T, et al. PET-CT staging of DLBCL accurately identifies and provides new insight into the clinical significance of bone marrow involvement. Blood. 2013;122:61–7.CrossRef Khan AB, Barrington SF, Mikhaeel NG, Hunt AA, Cameron L, Morris T, et al. PET-CT staging of DLBCL accurately identifies and provides new insight into the clinical significance of bone marrow involvement. Blood. 2013;122:61–7.CrossRef
76.
Zurück zum Zitat Li R, Ravizzini GC, Gorin MA, Maurer T, Eiber M, Cooperberg MR, et al. The use of PET/CT in prostate cancer. Prostate Cancer Prostatic Dis. 2018;21:4–21.CrossRef Li R, Ravizzini GC, Gorin MA, Maurer T, Eiber M, Cooperberg MR, et al. The use of PET/CT in prostate cancer. Prostate Cancer Prostatic Dis. 2018;21:4–21.CrossRef
77.
Zurück zum Zitat Kannivelu A, Loke K, Kok T, Osmany S, Ali S, Suat-Jin L, et al. The role of PET/CT in the evaluation of skeletal metastases. Semin Musculoskelet Radiol. 2014;18:149–65.CrossRef Kannivelu A, Loke K, Kok T, Osmany S, Ali S, Suat-Jin L, et al. The role of PET/CT in the evaluation of skeletal metastases. Semin Musculoskelet Radiol. 2014;18:149–65.CrossRef
78.
Zurück zum Zitat Jambor I, Kuisma A, Ramadan S, Huovinen R, Sandell M, Kajander S, et al. Prospective evaluation of planar bone scintigraphy, SPECT, SPECT/CT, 18 F-NaF PET/CT and whole body 1.5T MRI, including DWI, for the detection of bone metastases in high risk breast and prostate cancer patients: SKELETA clinical trial. Acta Oncol. 2016;55:59–67.CrossRef Jambor I, Kuisma A, Ramadan S, Huovinen R, Sandell M, Kajander S, et al. Prospective evaluation of planar bone scintigraphy, SPECT, SPECT/CT, 18 F-NaF PET/CT and whole body 1.5T MRI, including DWI, for the detection of bone metastases in high risk breast and prostate cancer patients: SKELETA clinical trial. Acta Oncol. 2016;55:59–67.CrossRef
79.
Zurück zum Zitat Damle NA, Bal C, Bandopadhyaya GP, Kumar L, Kumar P, Malhotra A, et al. The role of 18F-fluoride PET-CT in the detection of bone metastases in patients with breast, lung and prostate carcinoma: a comparison with FDG PET/CT and 99mTc-MDP bone scan. Jpn J Radiol. 2013;31:262–9.CrossRef Damle NA, Bal C, Bandopadhyaya GP, Kumar L, Kumar P, Malhotra A, et al. The role of 18F-fluoride PET-CT in the detection of bone metastases in patients with breast, lung and prostate carcinoma: a comparison with FDG PET/CT and 99mTc-MDP bone scan. Jpn J Radiol. 2013;31:262–9.CrossRef
80.
Zurück zum Zitat Fanti S, Goffin K, Hadaschik BA, Herrmann K, Maurer T, MacLennan S, et al. Consensus statements on PSMA PET/CT response assessment criteria in prostate cancer. Eur J Nucl Med Mol Imaging. 2021;48:469–76.CrossRef Fanti S, Goffin K, Hadaschik BA, Herrmann K, Maurer T, MacLennan S, et al. Consensus statements on PSMA PET/CT response assessment criteria in prostate cancer. Eur J Nucl Med Mol Imaging. 2021;48:469–76.CrossRef
81.
Zurück zum Zitat Marcus C, Butler P, Bagrodia A, Cole S, Subramaniam RM. Fluorine-18-labeled fluciclovine PET/CT in primary and biochemical recurrent prostate cancer management. Am J Roentgenol. 2020;215:267–76.CrossRef Marcus C, Butler P, Bagrodia A, Cole S, Subramaniam RM. Fluorine-18-labeled fluciclovine PET/CT in primary and biochemical recurrent prostate cancer management. Am J Roentgenol. 2020;215:267–76.CrossRef
82.
Zurück zum Zitat Gabriel M, Decristoforo C, Kendler D, Dobrozemsky G, Heute D, Uprimny C, et al. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med. 2007;48:508–18.CrossRef Gabriel M, Decristoforo C, Kendler D, Dobrozemsky G, Heute D, Uprimny C, et al. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med. 2007;48:508–18.CrossRef
83.
Zurück zum Zitat Bredella MA, Caputo GR, Steinbach LS. Value of FDG positron emission tomography in conjunction with mr imaging for evaluating therapy response in patients with musculoskeletal sarcomas. Am J Roentgenol. 2002;179:1145–50.CrossRef Bredella MA, Caputo GR, Steinbach LS. Value of FDG positron emission tomography in conjunction with mr imaging for evaluating therapy response in patients with musculoskeletal sarcomas. Am J Roentgenol. 2002;179:1145–50.CrossRef
84.
Zurück zum Zitat Zhang Q, Xi Y, Li D, Yuan Z, Dong J. The utility of 18F-FDG PET and PET/CT in the diagnosis and staging of chondrosarcoma: a meta-analysis. J Orthop Surg. 2020;15:229.CrossRef Zhang Q, Xi Y, Li D, Yuan Z, Dong J. The utility of 18F-FDG PET and PET/CT in the diagnosis and staging of chondrosarcoma: a meta-analysis. J Orthop Surg. 2020;15:229.CrossRef
85.
Zurück zum Zitat Cheon GJ, Kim MS, Lee JA, Lee S-Y, Cho WH, Song WS, et al. Prediction model of chemotherapy response in osteosarcoma by 18 F-FDG PET and MRI. J Nucl Med. 2009;50:1435–40.CrossRef Cheon GJ, Kim MS, Lee JA, Lee S-Y, Cho WH, Song WS, et al. Prediction model of chemotherapy response in osteosarcoma by 18 F-FDG PET and MRI. J Nucl Med. 2009;50:1435–40.CrossRef
86.
Zurück zum Zitat Subhawong TK, Winn A, Shemesh SS, Pretell-Mazzini J. F-18 FDG PET differentiation of benign from malignant chondroid neoplasms: a systematic review of the literature. Skeletal Radiol. 2017;46:1233–9.CrossRef Subhawong TK, Winn A, Shemesh SS, Pretell-Mazzini J. F-18 FDG PET differentiation of benign from malignant chondroid neoplasms: a systematic review of the literature. Skeletal Radiol. 2017;46:1233–9.CrossRef
87.
Zurück zum Zitat Warbey VS, Ferner RE, Dunn JT, Calonje E, O’Doherty MJ. [18F]FDG PET/CT in the diagnosis of malignant peripheral nerve sheath tumours in neurofibromatosis type-1. Eur J Nucl Med Mol Imaging. 2009;36:751–7.CrossRef Warbey VS, Ferner RE, Dunn JT, Calonje E, O’Doherty MJ. [18F]FDG PET/CT in the diagnosis of malignant peripheral nerve sheath tumours in neurofibromatosis type-1. Eur J Nucl Med Mol Imaging. 2009;36:751–7.CrossRef
88.
Zurück zum Zitat Ferner RE, Golding JF, Smith M, Calonje E, Jan W, Sanjayanathan V, et al. [18F]2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) as a diagnostic tool for neurofibromatosis 1 (NF1) associated malignant peripheral nerve sheath tumours (MPNSTs): a long-term clinical study. Ann Oncol. 2008;19:390–4.CrossRef Ferner RE, Golding JF, Smith M, Calonje E, Jan W, Sanjayanathan V, et al. [18F]2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) as a diagnostic tool for neurofibromatosis 1 (NF1) associated malignant peripheral nerve sheath tumours (MPNSTs): a long-term clinical study. Ann Oncol. 2008;19:390–4.CrossRef
89.
Zurück zum Zitat Chirindel A, Chaudhry M, Blakeley JO, Wahl R. 18 F-FDG PET/CT qualitative and quantitative evaluation in neurofibromatosis type 1 patients for detection of malignant transformation: comparison of early to delayed imaging with and without liver activity normalization. J Nucl Med. 2015;56:379–85.CrossRef Chirindel A, Chaudhry M, Blakeley JO, Wahl R. 18 F-FDG PET/CT qualitative and quantitative evaluation in neurofibromatosis type 1 patients for detection of malignant transformation: comparison of early to delayed imaging with and without liver activity normalization. J Nucl Med. 2015;56:379–85.CrossRef
Metadaten
Titel
Whole body imaging in musculoskeletal oncology: when, why, and how
verfasst von
Joao R. T. Vicentini
Miriam A. Bredella
Publikationsdatum
09.07.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 3/2023
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-022-04112-7

Weitere Artikel der Ausgabe 3/2023

Skeletal Radiology 3/2023 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.