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Erschienen in: Comparative Clinical Pathology 4/2007

01.11.2007 | Case Report

A complicated case of concurrent canine babesiosis and canine ehrlichiosis

verfasst von: Sukullaya Assarasakorn, Anuchai Niwetpathomwat

Erschienen in: Comparative Clinical Pathology | Ausgabe 4/2007

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Abstract

Canine babesiosis and canine ehrlichiosis are the major tick-borne diseases throughout the world. The concurrent infection between canine babesiosis and canine ehrlichiosis can occur in endemic regions. This report showed the clinical pathology and treatment outcome of concurrent infection in a dog admitted to a veterinary hospital. Based on the history, physical examination, and laboratory finding, the dog was diagnosed with neurological disorders induced by babesiosis and ehrlichiosis concurrent infection. The dog presented with moderate normocytic normochromic anemia, severe thrombocytopenia and moderately increased alkaline phosphatase. The symptoms were more complicated with high fever, seizure, and cardiopulmonary arrest. The condition was specifically treated with doxycycline and diminazene aceturate, but the dog died 2 days after admission. In conclusion, concurrent infection of canine babesiosis and canine ehrlichiosis can cause complicated clinical neurological compromise and result in mortality in dogs.
Literatur
Zurück zum Zitat Collett MG (2000) Survey of canine babesiosis in South Africa. J S Afr Vet Assoc 71:180–186PubMed Collett MG (2000) Survey of canine babesiosis in South Africa. J S Afr Vet Assoc 71:180–186PubMed
Zurück zum Zitat de Castro MB, Machado RZ, de Aquino LP et al (2004) Experimental acute canine monocytic ehrlichiosis: clinicopathological and immunopathological findings. Vet Parasitol 119:73–86PubMedCrossRef de Castro MB, Machado RZ, de Aquino LP et al (2004) Experimental acute canine monocytic ehrlichiosis: clinicopathological and immunopathological findings. Vet Parasitol 119:73–86PubMedCrossRef
Zurück zum Zitat Ewing SA, Buckner RG (1965) Manifestations of babesiosis, ehrlichiosis, and combined infections in the dog. Am J Vet Res 26(113):815–828PubMed Ewing SA, Buckner RG (1965) Manifestations of babesiosis, ehrlichiosis, and combined infections in the dog. Am J Vet Res 26(113):815–828PubMed
Zurück zum Zitat Frank JR, Breitschwerdt EB (1999) A retrospective study of ehrlichiosis in 62 dogs from North Carolina and Virginia. J Vet Intern Med 13:194–201PubMedCrossRef Frank JR, Breitschwerdt EB (1999) A retrospective study of ehrlichiosis in 62 dogs from North Carolina and Virginia. J Vet Intern Med 13:194–201PubMedCrossRef
Zurück zum Zitat Freeman MJ, Kirby BM, Panciera DL et al (1994) Hypotensive shock syndrome associated with acute Babesia canis infection in a dog. J Am Vet Med Assoc 204:94–96PubMed Freeman MJ, Kirby BM, Panciera DL et al (1994) Hypotensive shock syndrome associated with acute Babesia canis infection in a dog. J Am Vet Med Assoc 204:94–96PubMed
Zurück zum Zitat Furlanello T, Fiorio F, Caldin M et al (2005) Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy. Vet Parasitol 134:77–85PubMedCrossRef Furlanello T, Fiorio F, Caldin M et al (2005) Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy. Vet Parasitol 134:77–85PubMedCrossRef
Zurück zum Zitat Harrus S, Aroch I, Lavy E et al (1997) Clinical manifestations of infectious canine cyclic thrombocytopenia. Vet Rec 141:247–250PubMed Harrus S, Aroch I, Lavy E et al (1997) Clinical manifestations of infectious canine cyclic thrombocytopenia. Vet Rec 141:247–250PubMed
Zurück zum Zitat Jacobson LS, Clark IA (1994) The pathophysiology of canine babesiosis: new approaches to an old puzzle. J S Afr Vet Assoc 65:134–145PubMed Jacobson LS, Clark IA (1994) The pathophysiology of canine babesiosis: new approaches to an old puzzle. J S Afr Vet Assoc 65:134–145PubMed
Zurück zum Zitat Krause PJ, Spielman A, Telford SR III et al (1998) Persistent parasitemia after acute babesiosis. N Engl J Med 339:160–165PubMedCrossRef Krause PJ, Spielman A, Telford SR III et al (1998) Persistent parasitemia after acute babesiosis. N Engl J Med 339:160–165PubMedCrossRef
Zurück zum Zitat Lobetti RG (2000) Canine babesiosis. In: Day MJ, Mackin A, Littlewood JD (eds) BSAVA manual of canine and feline haematology and transfusion medicine. BSAVA, Gloucester, pp 85–91 Lobetti RG (2000) Canine babesiosis. In: Day MJ, Mackin A, Littlewood JD (eds) BSAVA manual of canine and feline haematology and transfusion medicine. BSAVA, Gloucester, pp 85–91
Zurück zum Zitat Macintire DK, Drobatz KJ, Haskins SC, Saxon WD (2005) Neurologic emergencies. In: manual of small animal emergency and critical care medicine. Lippincott Williams & Wilkins, Baltimore, pp 251–269 Macintire DK, Drobatz KJ, Haskins SC, Saxon WD (2005) Neurologic emergencies. In: manual of small animal emergency and critical care medicine. Lippincott Williams & Wilkins, Baltimore, pp 251–269
Zurück zum Zitat Manzillo VF, Cappiello S, Oliva G (2006) Tick-transmitted diseases in dogs: clinicopathological findings. Parassitologia 48:135–136PubMed Manzillo VF, Cappiello S, Oliva G (2006) Tick-transmitted diseases in dogs: clinicopathological findings. Parassitologia 48:135–136PubMed
Zurück zum Zitat Maretzki CH, Fisher DJ, Greene CE (1994) Granulocytic ehrlichiosis and meningitis in a dog. J Am Vet Med Assoc 205:1554–1556PubMed Maretzki CH, Fisher DJ, Greene CE (1994) Granulocytic ehrlichiosis and meningitis in a dog. J Am Vet Med Assoc 205:1554–1556PubMed
Zurück zum Zitat Matthewman LA, Kelly PJ, Bobade PA et al (1993) Infections with Babesia canis and Ehrlichia canis in dogs in Zimbabwe. Vet Rec 133:344–346PubMed Matthewman LA, Kelly PJ, Bobade PA et al (1993) Infections with Babesia canis and Ehrlichia canis in dogs in Zimbabwe. Vet Rec 133:344–346PubMed
Zurück zum Zitat Nel M, Lobetti RG, Keller N et al (2004) Prognostic value of blood lactate, blood glucose, and hematocrit in canine babesiosis. J Vet Intern Med 18:471–476PubMedCrossRef Nel M, Lobetti RG, Keller N et al (2004) Prognostic value of blood lactate, blood glucose, and hematocrit in canine babesiosis. J Vet Intern Med 18:471–476PubMedCrossRef
Zurück zum Zitat Niwetpathomwat A, Techangamsuwan S, Suvarnavibhaja S (2006a) A retrospective study of clinical hematology and biochemistry of canine ehrlichiosis in an animal hospital populations in Bangkok, Thailand. Comp Clin Pathol 14:217–220CrossRef Niwetpathomwat A, Techangamsuwan S, Suvarnavibhaja S (2006a) A retrospective study of clinical hematology and biochemistry of canine ehrlichiosis in an animal hospital populations in Bangkok, Thailand. Comp Clin Pathol 14:217–220CrossRef
Zurück zum Zitat Niwetpathomwat A, Techangamsuwan S, Suvarnavibhaja S et al (2006b) A retrospective study of clinical hematology and biochemistry of canine babesiosis on hospital populations in Bangkok, Thailand. Comp Clin Pathol 15:110–112CrossRef Niwetpathomwat A, Techangamsuwan S, Suvarnavibhaja S et al (2006b) A retrospective study of clinical hematology and biochemistry of canine babesiosis on hospital populations in Bangkok, Thailand. Comp Clin Pathol 15:110–112CrossRef
Zurück zum Zitat Reyers F, Leisewitz AL, Lobetti RG et al (1998) Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria? Ann Trop Med Parasitol 92:503–511PubMedCrossRef Reyers F, Leisewitz AL, Lobetti RG et al (1998) Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria? Ann Trop Med Parasitol 92:503–511PubMedCrossRef
Zurück zum Zitat Suksawat J, Xuejie Y, Hancock SI et al (2001) Serologic and molecular evidence of coinfection with multiple vector-borne pathogens in dogs from Thailand. J Vet Intern Med 15:453–462PubMedCrossRef Suksawat J, Xuejie Y, Hancock SI et al (2001) Serologic and molecular evidence of coinfection with multiple vector-borne pathogens in dogs from Thailand. J Vet Intern Med 15:453–462PubMedCrossRef
Zurück zum Zitat Trapp SM, Dagnone AS, Vidotto O et al (2006) Seroepidemiology of canine babesiosis and ehrlichiosis in a hospital population. Vet Parasitol 140:223–230PubMedCrossRef Trapp SM, Dagnone AS, Vidotto O et al (2006) Seroepidemiology of canine babesiosis and ehrlichiosis in a hospital population. Vet Parasitol 140:223–230PubMedCrossRef
Zurück zum Zitat Welzl C, Leisewitz AL, Jacobson LS et al (2001) Systemic inflammatory response syndrome and multiple-organ damage/dysfunction in complicated canine babesiosis. J S Afr Vet Assoc 72:158–162PubMed Welzl C, Leisewitz AL, Jacobson LS et al (2001) Systemic inflammatory response syndrome and multiple-organ damage/dysfunction in complicated canine babesiosis. J S Afr Vet Assoc 72:158–162PubMed
Metadaten
Titel
A complicated case of concurrent canine babesiosis and canine ehrlichiosis
verfasst von
Sukullaya Assarasakorn
Anuchai Niwetpathomwat
Publikationsdatum
01.11.2007
Verlag
Springer-Verlag
Erschienen in
Comparative Clinical Pathology / Ausgabe 4/2007
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-007-0665-3

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