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16.10.2017 | Original Article

A novel utility of ^99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization

verfasst von: Tatsuaki Sumiyoshi, Yasuo Shima, Takehiro Okabayashi, Yasuhiro Hata, Yoshihiro Noda, Michihiko Kouno, Yuichi Saisaka, Kenta Sui, Sojiro Morita, Yuji Negoro, Taijiro Sueda

Erschienen in: Japanese Journal of Radiology | Ausgabe 12/2017

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Abstract

Purpose

Our aim was to determine the utility of Tc-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin single-photon-emission computed tomography (^99mTc-GSA SPECT/CT) fusion imaging for detecting incomplete portal vein embolization (PVE).

Materials and methods

Fifty-five candidates underwent PVE. Among them, five underwent second PVE. Detectability of first inadequate PVE using CT and ^99mTc-GSA SPECT/CT fusion imaging was analyzed.

Results

Cases of inadequate PVE were detected in three patients using CT and in five using ^99mTc-GSA SPECT/CT fusion imaging. Fusion imaging detected two cases of insufficient PVE in which portal branches were apparently well embolized on CT. Median value for volumetric rate in the embolized liver was 63.3% after the first PVE and 54.7% after the second (P < 0.01). Median functional rate value in embolized liver was 60.1% after the first PVE and 49.4% after the second (P < 0.01). Median value for change of volumetric and functional rates in embolized liver after the second PVE was 7.1 and 10.3%, respectively, and change of functional rate was greater than that of volumetric rate (P < 0.01).

Conclusions

^99mTc-GSA SPECT/CT fusion imaging was useful for detecting inadequate PVE, and second PVE was effective for increasing volumetric and functional rates.

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Titel: A novel utility of 99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization
verfasst von: Tatsuaki Sumiyoshi
Yasuo Shima
Takehiro Okabayashi
Yasuhiro Hata
Yoshihiro Noda
Michihiko Kouno
Yuichi Saisaka
Kenta Sui
Sojiro Morita
Yuji Negoro
Taijiro Sueda
Publikationsdatum: 16.10.2017
Verlag: Springer Japan
Erschienen in: Japanese Journal of Radiology / Ausgabe 12/2017
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-017-0689-9

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A novel utility of ^99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization