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Intensive Care Medicine
Erschienen in: Intensive Care Medicine 6/2018

12.05.2018 | Review

A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill

verfasst von: Jean-François Timsit, Mark Rupp, Emilio Bouza, Vineet Chopra, Tarja Kärpänen, Kevin Laupland, Thiago Lisboa, Leonard Mermel, Olivier Mimoz, Jean-Jacques Parienti, Garyphalia Poulakou, Bertrand Souweine, Walter Zingg

Erschienen in: Intensive Care Medicine | Ausgabe 6/2018

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Abstract

Intravascular catheters are inserted into almost all critically ill patients. This review provides up-to-date insight into available knowledge on epidemiology and diagnosis of complications of central vein and arterial catheters in ICU. It discusses the optimal therapy of catheter-related infections and thrombosis. Prevention of complications is a multidisciplinary task that combines both improvement of the process of care and introduction of new technologies. We emphasize the main component of the prevention strategies that should be used in critical care and propose areas of future investigation in this field.
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Literatur
1.
Timsit JF, L’Heriteau F, Lepape A, Francais A, Ruckly S, Venier AG, Jarno P, Boussat S, Coignard B, Savey A (2012) A multicentre analysis of catheter-related infection based on a hierarchical model. Intensive Care Med 38(10):1662–1672PubMedCrossRef
2.
de Lassence A, Timsit JF, Tafflet M, Azoulay E, Jamali S, Vincent F, Cohen Y, Garrouste-Orgeas M, Alberti C, Dreyfuss D (2006) Pneumothorax in the intensive care unit: incidence, risk factors, and outcome. Anesthesiology 104(1):5–13PubMedCrossRef
3.
Siempos II, Kopterides P, Tsangaris I, Dimopoulou I, Armaganidis AE (2009) Impact of catheter-related bloodstream infections on the mortality of critically ill patients: a meta-analysis. Crit Care Med 37(7):2283–2289PubMedCrossRef
4.
Soufir L, Timsit JF, Mahe C, Carlet J, Regnier B, Chevret S (1999) Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study. Infect Control Hosp Epidemiol 20(6):396–401PubMedCrossRef
5.
Nuckols TK, Keeler E, Morton SC, Anderson L, Doyle B, Booth M, Shanman R, Grein J, Shekelle P (2016) Economic evaluation of quality improvement interventions for bloodstream infections related to central catheters: a systematic review. JAMA InternMed 176(12):1843–1854
6.
Pages J, Hazera P, Megarbane B, du Cheyron D, Thuong M, Dutheil JJ, Valette X, Fournel F, Mermel LA, Mira JP et al (2016) Comparison of alcoholic chlorhexidine and povidone-iodine cutaneous antiseptics for the prevention of central venous catheter-related infection: a cohort and quasi-experimental multicenter study. Intensive Care Med 42(9):1418–1426PubMedCrossRef
7.
Lucet JC, Boudama L, Zahar JR, Schwebel C, Geffory A, Pease S, Herault MC, Haouache H, Adrie C, Thuong M et al (2010) Infectious risk associated with arterial catheters compared to central venous catheters. Crit Care Med 38(4):552–559CrossRef
8.
Pronovost P, Needham D, Berenholtz S, Sinopoli D, Chu H, Cosgrove S, Sexton B, Hyzy R, Welsh R, Roth G et al (2006) An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med 355(26):2725–2732PubMedCrossRef
9.
Calvino-Gunther S, Schwebel C, Hamidfar-Roy R, Bonadona A, Lugosi M, Ara-Somohano C, Minet C, Potton L, Cartier JC, Vesin A et al (2016) Complications of intravascular catheters in ICU: definitions, incidence and severity. A randomized controlled trial comparing usual transparent dressings versus new-generation dressings (the advanced study). Intensive Care Med 42(11):1753–1765PubMedCrossRef
10.
Minet C, Lugosi M, Savoye PY, Menez C, Ruckly S, Bonadona A, Schwebel C, Hamidfar-Roy R, Dumanoir P, Ara-Somohano C et al (2012) Pulmonary embolism in mechanically ventilated patients requiring computed tomography: prevalence, risk factors, and outcome. Crit Care Med 40(12):3202–3208PubMedCrossRef
11.
Fletcher JJ, Wilson TJ, Rajajee V, Stetler WR Jr, Jacobs TL, Sheehan KM, Brown DL (2016) A randomized trial of central venous catheter type and thrombosis in critically ill neurologic patients. Neurocrit Care 25(1):20–28PubMedCrossRef
12.
Chopra V, Priya A, Pekow PS, Thompson R, Flanders SA, Lindenauer PK (2016) Variation in prevalence and patterns of peripherally inserted central catheter use in adults hospitalized with pneumonia. J Hosp Med 11(8):568–575PubMedCrossRef
13.
Pikwer A, Akeson J, Lindgren S (2012) Complications associated with peripheral or central routes for central venous cannulation. Anaesthesia 67(1):65–71PubMedCrossRef
14.
Chopra V, Anand S, Hickner A, Buist M, Rogers MA, Saint S, Flanders SA (2013) Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis. Lancet 382(9889):311–325PubMedCrossRef
15.
Chopra V, Flanders SA, Saint S, Woller SC, O’Grady NP, Safdar N, Trerotola SO, Saran R, Moureau N, Wiseman S et al (2015) The Michigan appropriateness guide for intravenous catheters (MAGIC): results from a multispecialty panel using the RAND/UCLA appropriateness method. Ann Intern Med 163(6 Suppl):S1–S40PubMedCrossRef
16.
Chopra V, O’Horo JC, Rogers MA, Maki DG, Safdar N (2013) The risk of bloodstream infection associated with peripherally inserted central catheters compared with central venous catheters in adults: a systematic review and meta-analysis. Infect Control Hosp Epidemiol 34(9):908–918PubMedCrossRef
17.
Truche AS, Darmon M, Bailly S, Clec’h C, Dupuis C, Misset B, Azoulay E, Schwebel C, Bouadma L, Kallel H et al (2016) Continuous renal replacement therapy versus intermittent hemodialysis in intensive care patients: impact on mortality and renal recovery. Intensive Care Med 42(9):1408–1417PubMedCrossRef
18.
Parienti JJ, Thirion M, Megarbane B, Souweine B, Ouchikhe A, Polito A, Forel JM, Marque S, Misset B, Airapetian N et al (2008) Femoral versus jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA 299(20):2413–2422PubMedCrossRef
19.
Souweine B, Liotier J, Heng AE, Isnard M, Ackoundou-N’Guessan C, Deteix P, Traore O (2006) Catheter colonization in acute renal failure patients: comparison of central venous and dialysis catheters. Am J Kidney Dis 47(5):879–887PubMedCrossRef
20.
Chua HR, Schneider AG, Sherry NL, Lotfy N, Chan MJ, Galtieri J, Wong GR, Lipcsey M, Matte Cde A, Collins A et al (2014) Initial and extended use of femoral versus nonfemoral double-lumen vascular catheters and catheter-related infection during continuous renal replacement therapy. Am J Kidney Dis 64(6):909–917PubMedCrossRef
21.
Parienti JJ, Dugue AE, Daurel C, Mira JP, Megarbane B, Mermel LA, Daubin C, du Cheyron D (2010) Continuous renal replacement therapy may increase the risk of catheter infection. Clin J Am Soc Nephrol 5(8):1489–1496PubMedPubMedCentralCrossRef
22.
Souweine B, Traore O, Aublet-Cuvelier B, Badrikian L, Bret L, Sirot J, Gazuy N, Laveran H, Deteix P (1999) Dialysis and central venous catheter infections in critically ill patients: results of a prospective study. Crit Care Med 27(11):2394–2398PubMedCrossRef
23.
Coupez E, Timsit JF, Ruckly S, Schwebel C, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M et al (2016) Guidewire exchange versus new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction? Crit Care 20(1):230PubMedPubMedCentralCrossRef
24.
Chatzinikolaou I, Finkel K, Hanna H, Boktour M, Foringer J, Ho T, Raad I (2003) Antibiotic-coated hemodialysis catheters for the prevention of vascular catheter-related infections: a prospective, randomized study. Am J Med 115(5):352–357PubMedCrossRef
25.
Hermite L, Quenot JP, Nadji A, Barbar SD, Charles PE, Hamet M, Jacquiot N, Ghiringhelli F, Freysz M (2012) Sodium citrate versus saline catheter locks for non-tunneled hemodialysis central venous catheters in critically ill adults: a randomized controlled trial. Intensive Care Med 38(2):279–285PubMedCrossRef
26.
Parienti JJ, Deryckere S, Megarbane B, Valette X, Seguin A, Sauneuf B, Mira JP, Souweine B, Cattoir V, Daubin C et al (2014) Quasi-experimental study of sodium citrate locks and the risk of acute hemodialysis catheter infection among critically ill patients. Antimicrob Agents Chemother 58(10):5666–5672PubMedPubMedCentralCrossRef
27.
Souweine B, Lautrette A, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F et al (2015) Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial. Am J Respir Crit Care Med 191(9):1024–1032PubMedCrossRef
28.
Parienti JJ, Megarbane B, Fischer MO, Lautrette A, Gazui N, Marin N, Hanouz JL, Ramakers M, Daubin C, Mira JP et al (2010) Catheter dysfunction and dialysis performance according to vascular access among 736 critically ill adults requiring renal replacement therapy: a randomized controlled study. Crit Care Med 38(4):1118–1125PubMedCrossRef
29.
Simon EM, Summers SM (2017) Vascular access complications: an emergency medicine approach. Emerg Med Clin N Am 35(4):771–788CrossRef
30.
Traore O, Liotier J, Souweine B (2005) Prospective study of arterial and central venous catheter colonization and of arterial- and central venous catheter-related bacteremia in intensive care units. Crit Care Med 33(6):1276–1280PubMedCrossRef
31.
Mermel LA (2011) What is the predominant source of intravascular catheter infections? Clin Infect Dis 52(2):211–212PubMedCrossRef
32.
Beloin C, Fernandez-Hidalgo N, Lebeaux D (2017) Understanding biofilm formation in intravascular device-related infections. Intensive Care Med 43(3):443–446PubMedCrossRef
33.
Flemming HC, Wingender J, Szewzyk U, Steinberg P, Rice SA, Kjelleberg S (2016) Biofilms: an emergent form of bacterial life. Nat Rev Microbiol 14(9):563–575PubMedCrossRef
34.
Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284(5418):1318–1322PubMedCrossRef
35.
Raad II, Fang X, Keutgen XM, Jiang Y, Sherertz R, Hachem R (2008) The role of chelators in preventing biofilm formation and catheter-related bloodstream infections. Curr Opin Infect Dis 21(4):385–392PubMedCrossRef
36.
Lin MY, Hota B, Khan YM, Woeltje KF, Borlawsky TB, Doherty JA, Stevenson KB, Weinstein RA, Trick WE (2010) Quality of traditional surveillance for public reporting of nosocomial bloodstream infection rates. JAMA 304(18):2035–2041PubMedCrossRef
37.
Timsit JF, Lugosi M, Minet C, Schwebel C (2011) Should we still need to systematically perform catheter culture in the intensive care unit? Crit Care Med 39:1556–1558PubMedCrossRef
38.
Shuman EK, Washer LL, Arndt JL, Zalewski CA, Hyzy RC, Napolitano LM, Chenoweth CE (2010) Analysis of central line-associated bloodstream infections in the intensive care unit after implementation of central line bundles. Infect Control Hosp Epidemiol 31(5):551–553PubMedCrossRef
39.
Worth LJ, Brett J, Bull AL, McBryde ES, Russo PL, Richards MJ (2009) Impact of revising the national nosocomial infection surveillance system definition for catheter-related bloodstream infection in ICU: reproducibility of the National Healthcare Safety Network case definition in an Australian cohort of infection control professionals. Am J Infect Control 37(8):643–648PubMedCrossRef
40.
Safdar N, Maki DG (2002) Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters. Crit Care Med 30(12):2632–2635PubMedCrossRef
41.
Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S et al (2015) Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial. Lancet 386(10008):2069–2077PubMedCrossRef
42.
Parienti JJ, Mongardon N, Megarbane B, Mira JP, Kalfon P, Gros A, Marque S, Thuong M, Pottier V, Ramakers M et al (2015) Intravascular complications of central venous catheterization by insertion site. N Engl J Med 373(13):1220–1229PubMedCrossRef
43.
Timsit JF, Schwebel C, Bouadma L, Geffroy A, Garrouste-Orgeas M, Pease S, Herault MC, Haouache H, Calvino-Gunther S, Gestin B et al (2009) Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA 301(12):1231–1241PubMedCrossRef
44.
Sherertz RJ, Raad II, Belani A, Koo LC, Rand KH, Pickett DL, Straub SA, Fauerbach LL (1990) Three-year experience with sonicated vascular catheter cultures in a clinical microbiology laboratory. J Clin Microbiol 28(1):76–82PubMedPubMedCentral
45.
Maki DG, Weise CE, Sarafin HW (1977) A semiquantitative culture method for identifying intravenous-catheter-related infection. N Engl J Med 296(23):1305–1309PubMedCrossRef
46.
Safdar N, Fine JP, Maki DG (2005) Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection. Ann Intern Med 142(6):451–466PubMedCrossRef
47.
Brun-Buisson C, Abrouk F, Legrand P, Huet Y, Larabi S, Rapin M (1987) Diagnosis of central venous catheter-related sepsis. Critical level of quantitative tip cultures. Arch Intern Med 147(5):873–877PubMedCrossRef
48.
Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O’Grady NP, Raad II, Rijnders BJ, Sherertz RJ, Warren DK (2009) Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 49(1):1–45PubMedPubMedCentralCrossRef
49.
Bouza E, Sousa D, Rodriguez-Creixems M, Lechuz JG, Munoz P (2007) Is the volume of blood cultured still a significant factor in the diagnosis of bloodstream infections? J Clin Microbiol 45(9):2765–2769PubMedPubMedCentralCrossRef
50.
Slobbe L, El Barzouhi A, Boersma E, Rijnders BJ (2009) Comparison of the roll plate method to the sonication method to diagnose catheter colonization and bacteremia in patients with long-term tunnelled catheters: a randomized prospective study. J Clin Microbiol 47(4):885–888PubMedPubMedCentralCrossRef
51.
Souweine B, Heng AE, Aumeran C, Thiolliere F, Gazuy N, Deteix P, Traore O (2008) Do antibiotics administered at the time of central venous catheter removal interfere with the evaluation of colonization? Intensive Care Med 34(2):286–291PubMedCrossRef
52.
Vandecasteele SJ, Van Eldere J, Merckx R, Peetermans WE (2004) The effect of systemic antibiotics on the microbiological diagnosis of experimental foreign body infections caused by Staphylococcus epidermidis. Diagn Microbiol Infect Dis 48(2):89–95PubMedCrossRef
53.
Rijnders BJ, Peetermans WE, Verwaest C, Wilmer A, Van Wijngaerden E (2004) Watchful waiting versus immediate catheter removal in ICU patients with suspected catheter-related infection: a randomized trial. Intensive Care Med 30(6):1073–1080PubMedCrossRef
54.
Bouza E, Munoz P, Burillo A, Lopez-Rodriguez J, Fernandez-Perez C, Perez MJ, Rincon C (2005) The challenge of anticipating catheter tip colonization in major heart surgery patients in the intensive care unit: are surface cultures useful? Crit Care Med 33(9):1953–1960PubMedCrossRef
55.
Fernandez-Cruz A, Martin-Rabadan P, Suarez-Salas M, Rojas-Wettig L, Perez MJ, Guinea J, Guembe M, Pelaez T, Sanchez-Carrillo C, Bouza E (2014) Is it feasible to diagnose catheter-related candidemia without catheter withdrawal? Med Mycol 52(5):491–497PubMedCrossRef
56.
Blot F, Nitenberg G, Chachaty E, Raynard B, Germann N, Antoun S, Laplanche A, Brun-Buisson C, Tancrede C (1999) Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures. Lancet 354(9184):1071–1077PubMedCrossRef
57.
Raad I, Hanna HA, Alakech B, Chatzinikolaou I, Johnson MM, Tarrand J (2004) Differential time to positivity: a useful method for diagnosing catheter-related bloodstream infections. Ann Intern Med 140(1):18–25PubMedCrossRef
58.
Bouza E, Alvarado N, Alcala L, Sanchez-Conde M, Perez MJ, Munoz P, Martin-Rabadan P, Rodriguez-Creixems M (2005) A prospective, randomized, and comparative study of 3 different methods for the diagnosis of intravascular catheter colonization. Clin Infect Dis 40(8):1096–1100PubMedCrossRef
59.
Catton JA, Dobbins BM, Kite P, Wood JM, Eastwood K, Sugden S, Sandoe JA, Burke D, McMahon MJ, Wilcox MH (2005) In situ diagnosis of intravascular catheter-related bloodstream infection: a comparison of quantitative culture, differential time to positivity, and endoluminal brushing. Crit Care Med 33(4):787–791PubMedCrossRef
60.
Guembe M, Rodriguez-Creixems M, Sanchez-Carrillo C, Perez-Parra A, Martin-Rabadan P, Bouza E (2010) How many lumens should be cultured in the conservative diagnosis of catheter-related bloodstream infections? Clin Infect Dis 50(12):1575–1579PubMedCrossRef
61.
Bouza E, Martin-Rabadan P, Echenagusia A, Camunez F, Rodriguez-Rosales G, Simo G, Echenagusia M, Guembe M (2014) Diagnosis of venous access port colonization requires cultures from multiple sites: should guidelines be amended? Diagn Microbiol Infect Dis 78(2):162–167PubMedCrossRef
62.
Rijnders BJ, Van Wijngaerden E, Peetermans WE (2002) Catheter-tip colonization as a surrogate end point in clinical studies on catheter-related bloodstream infection: how strong is the evidence? Clin Infect Dis 35(9):1053–1058PubMedCrossRef
63.
Mrozec N, Lautrette A, Aumeran C, Laurichesse H, Forestier C, Traore O, Souweine B (2011) Bloodstream infection following positive catheter cultures, what are the risks in the ICU when catheters are routinely cultured upon removal? Crit Care Med 39(6):1301–1305CrossRef
64.
Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R et al (2012) Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults. Am J Respir Crit Care Med 186(12):1272–1278PubMedCrossRef
65.
Zafar U, Riederer K, Khatib R, Szpunar S, Sharma M (2009) Relevance of isolating Staphylococcus aureus from intravascular catheters without positive blood culture. J Hosp Infect 71(2):193–195PubMedCrossRef
66.
Ruhe JJ, Menon A (2006) Clinical significance of isolated Staphylococcus aureus central venous catheter tip cultures. Clin Microbiol Infect 12(9):933–936PubMedCrossRef
67.
Ekkelenkamp MB, van der Bruggen T, van de Vijver DA, Wolfs TF, Bonten MJ (2008) Bacteremic complications of intravascular catheters colonized with Staphylococcus aureus. Clin Infect Dis 46(1):114–118PubMedCrossRef
68.
Timsit JF, Farkas JC, Boyer JM, Martin JB, Misset B, Renaud B, Carlet J (1998) Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis. Chest 114(1):207–213PubMedCrossRef
69.
Akova M, Daikos GL, Tzouvelekis L, Carmeli Y (2012) Interventional strategies and current clinical experience with carbapenemase-producing gram-negative bacteria. Clin Microbiol Infect 18(5):439–448PubMedCrossRef
70.
Lorente L, Jimenez A, Santana M, Iribarren JL, Jimenez JJ, Martin MM, Mora ML (2007) Microorganisms responsible for intravascular catheter-related bloodstream infection according to the catheter site. Crit Care Med 35(10):2424–2427PubMedCrossRef
71.
Safdar N, Handelsman J, Maki DG (2004) Does combination antimicrobial therapy reduce mortality in gram-negative bacteraemia? A meta-analysis. Lancet Infect Dis 4(8):519–527PubMedCrossRef
72.
Cornely OA, Bassetti M, Calandra T, Garbino J, Kullberg BJ, Lortholary O, Meersseman W, Akova M, Arendrup MC, Arikan-Akdagli S et al (2012) ESCMID guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients. Clin Microbiol Infect 18(Suppl 7):19–37PubMedCrossRef
73.
Merrer J, De Jonghe B, Golliot F, Lefrant JY, Raffy B, Barre E, Rigaud JP, Casciani D, Misset B, Bosquet C et al (2001) Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial. JAMA 286(6):700–707PubMedCrossRef
74.
O’Horo JC, Maki DG, Krupp AE, Safdar N (2014) Arterial catheters as a source of bloodstream infection: a systematic review and meta-analysis. Crit Care Med 42(6):1334–1339PubMedCrossRef
75.
Brass P, Hellmich M, Kolodziej L, Schick G, Smith AF (2015) Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization. Cochrane Database Syst Rev 1:CD006962PubMed
76.
Brass P, Hellmich M, Kolodziej L, Schick G, Smith AF (2015) Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization. Cochrane Database Syst Rev 1:CD011447PubMed
77.
Milling TJ Jr, Rose J, Briggs WM, Birkhahn R, Gaeta TJ, Bove JJ, Melniker LA (2005) Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: the third sonography outcomes assessment program (SOAP-3) trial. Crit Care Med 33(8):1764–1769PubMedCrossRef
78.
Li J, Fan YY, Xin MZ, Yan J, Hu W, Huang WH, Lin XL, Qin HY (2014) A randomised, controlled trial comparing the long-term effects of peripherally inserted central catheter placement in chemotherapy patients using B-mode ultrasound with modified Seldinger technique versus blind puncture. Eur J Oncol Nurs 18(1):94–103PubMedCrossRef
79.
Soni NJ, Reyes LF, Keyt H, Arango A, Gelfond JA, Peters JI, Levine SM, Adams SG, Restrepo MI (2016) Use of ultrasound guidance for central venous catheterization: a national survey of intensivists and hospitalists. J Crit Care 36:277–283PubMedCrossRef
80.
Mimoz O, Chopra V, Timsit JF (2016) What’s new in catheter-related infection: skin cleansing and skin antisepsis. Intensive Care Med 42(11):1784–1786PubMedCrossRef
81.
Casey AL, Badia JM, Higgins A, Korndorffer J, Mantyh C, Mimoz O, Moro M (2017) Skin antisepsis: it’s not only what you use, it’s the way that you use it. J Hosp Infect 96(3):221–222PubMedCrossRef
82.
Mimoz O, Chopra V, Widmer A (2016) What’s new in skin antisepsis for short-term intravascular catheters: new data to address old problems? Intensive Care Med 42(12):2043–2045PubMedCrossRef
83.
Wang JT, Sheng WH, Wang JL, Chen D, Chen ML, Chen YC, Chang SC (2008) Longitudinal analysis of chlorhexidine susceptibilities of nosocomial methicillin-resistant Staphylococcus aureus isolates at a teaching hospital in Taiwan. J Antimicrob Chemother 62(3):514–517PubMedCrossRef
84.
Lee AS, Macedo-Vinas M, Francois P, Renzi G, Schrenzel J, Vernaz N, Pittet D, Harbarth S (2011) Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study. Clin Infect Dis 52(12):1422–1430PubMedCrossRef
85.
86.
Climo MW, Yokoe DS, Warren DK, Perl TM, Bolon M, Herwaldt LA, Weinstein RA, Sepkowitz KA, Jernigan JA, Sanogo K et al (2013) Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med 368(6):533–542PubMedPubMedCentralCrossRef
87.
Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F et al (2013) Targeted versus universal decolonization to prevent ICU infection. N Engl J Med 368(24):2255–2265PubMedCrossRef
88.
Milstone AM, Elward A, Song X, Zerr DM, Orscheln R, Speck K, Obeng D, Reich NG, Coffin SE, Perl TM (2013) Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trial. Lancet 381(9872):1099–1106PubMedPubMedCentralCrossRef
89.
90.
91.
Hockenhull JC, Dwan KM, Smith GW, Gamble CL, Boland A, Walley TJ, Dickson RC (2009) The clinical effectiveness of central venous catheters treated with anti-infective agents in preventing catheter-related bloodstream infections: a systematic review. Crit Care Med 37(2):702–712PubMedCrossRef
92.
Falagas ME, Fragoulis K, Bliziotis IA, Chatzinikolaou I (2007) Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials. J Antimicrob Chemother 59(3):359–369PubMedCrossRef
93.
Ramos ER, Reitzel R, Jiang Y, Hachem RY, Chaftari AM, Chemaly RF, Hackett B, Pravinkumar SE, Nates J, Tarrand JJ et al (2011) Clinical effectiveness and risk of emerging resistance associated with prolonged use of antibiotic-impregnated catheters: more than 0.5 million catheter days and 7 years of clinical experience. Crit Care Med. https://​doi.​org/​10.​1097/​CCM.​0b013e3181feb83e​ PubMedCrossRef
94.
Zacharioudakis IM, Zervou FN, Arvanitis M, Ziakas PD, Mermel LA, Mylonakis E (2014) Antimicrobial lock solutions as a method to prevent central line-associated bloodstream infections: a meta-analysis of randomized controlled trials. Clin Infect Dis 59(12):1741–1749PubMedCrossRef
95.
Landry DL, Braden GL, Gobeille SL, Haessler SD, Vaidya CK, Sweet SJ (2010) Emergence of gentamicin-resistant bacteremia in hemodialysis patients receiving gentamicin lock catheter prophylaxis. Clin J Am Soc Nephrol 5(10):1799–1804PubMedPubMedCentralCrossRef
96.
97.
Longo R, Llorens M, Goetz C, Platini C, Eid N, Sellies J, Ouamara N, Quetin P (2017) Taurolidine/citrate lock therapy for primary prevention of catheter-related infections in cancer patients: results of a prospective, randomized, phase IV trial (ATAPAC). Oncology 93(2):99–105PubMedCrossRef
98.
Zhao Y, Li Z, Zhang L, Yang J, Yang Y, Tang Y, Fu P (2014) Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials. Am J Kidney Dis 63(3):479–490PubMedCrossRef
99.
Correa Barcellos F, Nunes BP, Valle LJ, Lopes T, Orlando B, Scherer C, Nunes M, Araujo Duarte G, Bohlke M (2017) Comparative effectiveness of 30% trisodium citrate and heparin lock solution in preventing infection and dysfunction of hemodialysis catheters: a randomized controlled trial (CITRIM trial). Infection 45(2):139–145PubMedCrossRef
100.
Tribler S, Brandt CF, Petersen AH, Petersen JH, Fuglsang KA, Staun M, Broebech P, Moser CE, Jeppesen PB (2017) Taurolidine-citrate-heparin lock reduces catheter-related bloodstream infections in intestinal failure patients dependent on home parenteral support: a randomized, placebo-controlled trial. Am J Clin Nutr 106(3):839–848PubMed
101.
Bruyere R, Soudry-Faure A, Capellier G, Binquet C, Nadji A, Torner S, Blasco G, Yannaraki M, Barbar SD, Quenot JP (2014) Comparison of heparin to citrate as a catheter locking solution for non-tunneled central venous hemodialysis catheters in patients requiring renal replacement therapy for acute renal failure (VERROU-REA study): study protocol for a randomized controlled trial. Trials 15:449PubMedPubMedCentralCrossRef
102.
Raad II, Luna M, Khalil SA, Costerton JW, Lam C, Bodey GP (1994) The relationship between the thrombotic and infectious complications of central venous catheters. JAMA 271(13):1014–1016PubMedCrossRef
103.
Timsit JF, Bruneel F, Cheval C, Mamzer MF, Garrouste-Orgeas M, Wolff M, Misset B, Chevret S, Regnier B, Carlet J (1999) Use of tunneled femoral catheters to prevent catheter-related infection. A randomized, controlled trial. Ann Intern Med 130(9):729–735PubMedCrossRef
104.
Chopra V, Kaatz S, Conlon A, Paje D, Grant PJ, Rogers MAM, Bernstein SJ, Saint S, Flanders SA (2017) The Michigan risk score to predict peripherally inserted central catheter-associated thrombosis. J Thromb Haemost 15(10):1951–1962PubMedCrossRef
105.
Zhong L, Wang HL, Xu B, Yuan Y, Wang X, Zhang YY, Ji L, Pan ZM, Hu ZS (2017) Normal saline versus heparin for patency of central venous catheters in adult patients—a systematic review and meta-analysis. Crit Care 21(1):5PubMedPubMedCentralCrossRef
106.
107.
108.
Ernst FR, Chen E, Lipkin C, Tayama D, Amin AN (2014) Comparison of hospital length of stay, costs, and readmissions of alteplase versus catheter replacement among patients with occluded central venous catheters. J Hosp Med 9(8):490–496PubMedPubMedCentralCrossRef
109.
Marang-van de Mheen PJ, van Bodegom-Vos L (2016) Meta-analysis of the central line bundle for preventing catheter-related infections: a case study in appraising the evidence in quality improvement. BMJ Qual Saf 25(2):118–129PubMedCrossRef
110.
Furuya EY, Dick A, Perencevich EN, Pogorzelska M, Goldmann D, Stone PW (2011) Central line bundle implementation in US intensive care units and impact on bloodstream infections. PLoS One 6(1):e15452PubMedPubMedCentralCrossRef
111.
Weaver SJ, Weeks K, Pham JC, Pronovost PJ (2014) On the CUSP: stop BSI: evaluating the relationship between central line-associated bloodstream infection rate and patient safety climate profile. Am J Infect Control 42(10 Suppl):S203–S208PubMedPubMedCentralCrossRef
112.
Pronovost PJ, Weaver SJ, Berenholtz SM, Lubomski LH, Maragakis LL, Marsteller JA, Pham JC, Sawyer MD, Thompson DA, Weeks K et al (2017) Reducing preventable harm: observations on minimizing bloodstream infections. J Health Organ Manag 31(1):2–9PubMedCrossRef
113.
O’Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML et al (2011) Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 52(9):e162–e193PubMedPubMedCentralCrossRef
114.
Loveday HP, Wilson JA, Prieto J, Wilcox MH (2016) epic3: revised recommendation for intravenous catheter and catheter site care. J Hosp Infect 92(4):346–348PubMedCrossRef
115.
Marschall J, Mermel LA, Fakih M, Hadaway L, Kallen A, O’Grady NP, Pettis AM, Rupp ME, Sandora T, Maragakis LL et al (2014) Strategies to prevent central line-associated bloodstream infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 35(7):753–771PubMedCrossRef
116.
Shapey IM, Foster MA, Whitehouse T, Jumaa P, Bion JF (2009) Central venous catheter-related bloodstream infections: improving post-insertion catheter care. J Hosp Infect 71(2):117–122PubMedCrossRef
117.
Timsit JF, Bouadma L, Ruckly S, Schwebel C, Garrouste-Orgeas M, Bronchard R, Calvino-Gunther S, Laupland K, Adrie C, Thuong M et al (2012) Dressing disruption is a major risk factor for catheter-related infections. Crit Care Med 40(6):1707–1714PubMedCrossRef
118.
Ista E, van der Hoven B, Kornelisse RF, van der Starre C, Vos MC, Boersma E, Helder OK (2016) Effectiveness of insertion and maintenance bundles to prevent central-line-associated bloodstream infections in critically ill patients of all ages: a systematic review and meta-analysis. Lancet Infect Dis 16(6):724–734PubMedCrossRef
119.
Nicol PW, Watkins RE, Donovan RJ, Wynaden D, Cadwallader H (2009) The power of vivid experience in hand hygiene compliance. J Hosp Infect 72(1):36–42PubMedCrossRef
120.
Zingg W, Holmes A, Dettenkofer M, Goetting T, Secci F, Clack L, Allegranzi B, Magiorakos AP, Pittet D (2015) Hospital organisation, management, and structure for prevention of health-care-associated infection: a systematic review and expert consensus. Lancet Infect Dis 15(2):212–224PubMedCrossRef
121.
Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC (2009) Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci 4:50PubMedPubMedCentralCrossRef
122.
Blot K, Bergs J, Vogelaers D, Blot S, Vandijck D (2014) Prevention of central line-associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysis. Clin Infect Dis 59(1):96–105PubMedPubMedCentralCrossRef
123.
van der Kooi T, Sax H, Pittet D, van Dissel J, van Benthem B, Walder B, Cartier V, Clack L, de Greeff S, Wolkewitz M et al (2017) Prevention of hospital infections by intervention and training (PROHIBIT): results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections. Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-017-5007-6 PubMedCrossRef
124.
Zingg W, Cartier V, Inan C, Touveneau S, Theriault M, Gayet-Ageron A, Clergue F, Pittet D, Walder B (2014) Hospital-wide multidisciplinary, multimodal intervention programme to reduce central venous catheter-associated bloodstream infection. PLoS One 9(4):e93898PubMedPubMedCentralCrossRef
125.
Langgartner J, Linde HJ, Lehn N, Reng M, Scholmerich J, Gluck T (2004) Combined skin disinfection with chlorhexidine/propanol and aqueous povidone-iodine reduces bacterial colonisation of central venous catheters. Intensive Care Med 30(6):1081–1088PubMedCrossRef
126.
Patrick S, McDowell A, Lee A, Frau A, Martin U, Gardner E, McLorinan G, Eames N (2017) Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol versus povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria: a randomised controlled trial. Bone Joint J 99(10):1354–1365PubMedCrossRef
127.
Corley A, Cantara M, Gardner J, Trexler P, Rock C, Maragakis LL (2017) Central line-associated bloodstream infection rate elevation: attributable to National Healthcare Safety Network surveillance definition changes, ongoing opportunities for infection prevention, or both? Am J Infect Control 45(9):1030–1032PubMedCrossRef
Metadaten
Titel
A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill
verfasst von
Jean-François Timsit
Mark Rupp
Emilio Bouza
Vineet Chopra
Tarja Kärpänen
Kevin Laupland
Thiago Lisboa
Leonard Mermel
Olivier Mimoz
Jean-Jacques Parienti
Garyphalia Poulakou
Bertrand Souweine
Walter Zingg
Publikationsdatum
12.05.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 6/2018
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-018-5212-y

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