Skip to main content
Erschienen in: Intensive Care Medicine 2/2007

01.02.2007 | Pediatric Original

Acceptable respiratory physiologic limits for children during weaning from mechanical ventilation

verfasst von: Miriam Santschi, France Gauvin, Georges Hatzakis, Jacques Lacroix, Philippe Jouvet

Erschienen in: Intensive Care Medicine | Ausgabe 2/2007

Einloggen, um Zugang zu erhalten

Abstract

Objective

The aim of this survey was to characterize the physiological limits considered appropriate during weaning from mechanical ventilation in children.

Design

Two hundred twenty-two (222) intensivists from 63 pediatric intensive care units (PICUs) were asked to provide the limits they considered acceptable for respiratory rate (RR), tidal volume (VT) and end-tidal CO2 (PetCO2) during weaning from mechanical ventilation of a 3-month-old, a 2-year-old and a 10-year-old patient.

Setting

Pediatric intensivists working in Canada, France, Switzerland and Belgium.

Patients

None.

Interventions

None.

Results

Ninety-seven intensivists (43%) from 49 PICUs responded to the survey. The median minimal RR (25th;75th percentile) was: 20 breaths per minute (bpm) (15;25) for the 3-month-old, 15 bpm (10;15) for the 2-year-old and 10 bpm (10;15) for the 10-year-old patient. The median maximal RR was 50 bpm (40;60) for the 3-month-old, 40 bpm (30;40) for the 2-year-old and 30 bpm (30;40) for the 10-year-old child. The median minimal VT was 5 ml/kg (4;6) for the 3-month-old and 2-year-old patients and 5 ml/kg (5;6) for the 10-year-old. The median maximal PetCO2 was 55 mmHg (50;60) for the 3-month-old, 50 mmHg (45;50) for the 2-year-old and 50 mmHg (50;55) for the 10-year-old.

Conclusion

This survey indicated that acceptable weaning limits are broad, as stated by the responders. We need to organize and consolidate our thinking on weaning children from mechanical ventilation before guidelines can be established.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Farias JA, Frutos F, Esteban A, Flores JC, Retta A, Baltodano A, Alia I, Hatzis T, Olazarri F, Petros A, Johnson M (2004) What is the daily practice of mechanical ventilation in pediatric intensive care units? A multicenter study. Intensive Care Med 30:918–925PubMedCrossRef Farias JA, Frutos F, Esteban A, Flores JC, Retta A, Baltodano A, Alia I, Hatzis T, Olazarri F, Petros A, Johnson M (2004) What is the daily practice of mechanical ventilation in pediatric intensive care units? A multicenter study. Intensive Care Med 30:918–925PubMedCrossRef
2.
Zurück zum Zitat Schultz TR, Lin RJ, Watzman HM, Durning SM, Hales R, Woodson A, Francis B, Tyler L, Napoli L, Godinez RI (2001) Weaning children from mechanical ventilation: a prospective randomized trial of protocol-directed versus physician-directed weaning. Respir Care 46:772–782PubMed Schultz TR, Lin RJ, Watzman HM, Durning SM, Hales R, Woodson A, Francis B, Tyler L, Napoli L, Godinez RI (2001) Weaning children from mechanical ventilation: a prospective randomized trial of protocol-directed versus physician-directed weaning. Respir Care 46:772–782PubMed
3.
Zurück zum Zitat Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH (2002) Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. JAMA 288:2561–2568PubMedCrossRef Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH (2002) Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. JAMA 288:2561–2568PubMedCrossRef
4.
Zurück zum Zitat Kollef MH, Shapiro SD, Silver P, St John RE, Prentice D, Sauer S, Ahrens TS, Shannon W, Baker-Clinkscale D (1997) A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. Crit Care Med 25:567–574PubMedCrossRef Kollef MH, Shapiro SD, Silver P, St John RE, Prentice D, Sauer S, Ahrens TS, Shannon W, Baker-Clinkscale D (1997) A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. Crit Care Med 25:567–574PubMedCrossRef
5.
Zurück zum Zitat Marelich GP, Murin S, Battistella F, Inciardi J, Vierra T, Roby M (2000) Protocol weaning of mechanical ventilation in medical and surgical patients by respiratory care practitioners and nurses: effect on weaning time and incidence of ventilator-associated pneumonia. Chest 118:459–467PubMedCrossRef Marelich GP, Murin S, Battistella F, Inciardi J, Vierra T, Roby M (2000) Protocol weaning of mechanical ventilation in medical and surgical patients by respiratory care practitioners and nurses: effect on weaning time and incidence of ventilator-associated pneumonia. Chest 118:459–467PubMedCrossRef
6.
Zurück zum Zitat Strickland JH Jr, Hasson JH (1993) A computer-controlled ventilator weaning system. A clinical trial. Chest 103:1220–1226PubMed Strickland JH Jr, Hasson JH (1993) A computer-controlled ventilator weaning system. A clinical trial. Chest 103:1220–1226PubMed
7.
Zurück zum Zitat MacIntyre NR, Cook DJ, Ely EW Jr, Epstein SK, Fink JB, Heffner JE, Hess D, Hubmayer RD, Scheinhorn DJ (2001) Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest 120:375S–395SCrossRef MacIntyre NR, Cook DJ, Ely EW Jr, Epstein SK, Fink JB, Heffner JE, Hess D, Hubmayer RD, Scheinhorn DJ (2001) Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest 120:375S–395SCrossRef
8.
Zurück zum Zitat Lellouche F, Mancebo J, Roesler J, Jolliet P, Schortgen F, Cabello M, Bouadma L, Rodriguez P, Maggiore S, Qader S, Taille S, Brochard L (2004) Computer-driven ventilation reduces duration of weaning: a multicenter randomized controlled study. Intensive Care Med 30:S69 Lellouche F, Mancebo J, Roesler J, Jolliet P, Schortgen F, Cabello M, Bouadma L, Rodriguez P, Maggiore S, Qader S, Taille S, Brochard L (2004) Computer-driven ventilation reduces duration of weaning: a multicenter randomized controlled study. Intensive Care Med 30:S69
9.
Zurück zum Zitat Dojat M, Harf A, Touchard D, Lemaire F, Brochard L (2000) Clinical evaluation of a computer-controlled pressure support mode. Am J Respir Crit Care Med 161:1161–1166PubMed Dojat M, Harf A, Touchard D, Lemaire F, Brochard L (2000) Clinical evaluation of a computer-controlled pressure support mode. Am J Respir Crit Care Med 161:1161–1166PubMed
10.
Zurück zum Zitat Dojat M, Brochard L (2001) Knowledge-based systems for automatic ventilatory management. Respir Care Clin N Am 7:379–396PubMedCrossRef Dojat M, Brochard L (2001) Knowledge-based systems for automatic ventilatory management. Respir Care Clin N Am 7:379–396PubMedCrossRef
11.
Zurück zum Zitat Farges C, Hatzakis G, Lesage F, Dupic L, Hubert P, Brochard L, Jouvet P (2005) Computer-driven mechanical ventilation: a phase II clinical trial in children. Proceedings of the American Thoracic Society 2:A555 Farges C, Hatzakis G, Lesage F, Dupic L, Hubert P, Brochard L, Jouvet P (2005) Computer-driven mechanical ventilation: a phase II clinical trial in children. Proceedings of the American Thoracic Society 2:A555
13.
Zurück zum Zitat Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner DL (1995) Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. Canadian Critical Care Trials Group. JAMA 273:703–708PubMedCrossRef Cook DJ, Guyatt GH, Jaeschke R, Reeve J, Spanier A, King D, Molloy DW, Willan A, Streiner DL (1995) Determinants in Canadian health care workers of the decision to withdraw life support from the critically ill. Canadian Critical Care Trials Group. JAMA 273:703–708PubMedCrossRef
14.
Zurück zum Zitat Iliff A, Lee VA (1952) Pulse rate, respiratory rate, and body temperature of children between two months and eighteen years of age. Child Dev 23:237–245PubMedCrossRef Iliff A, Lee VA (1952) Pulse rate, respiratory rate, and body temperature of children between two months and eighteen years of age. Child Dev 23:237–245PubMedCrossRef
15.
Zurück zum Zitat Waring W (1983) The history and physical examination. In: Kendig E, Chernick V (ed) Disorders of the repiratory tract in children. Saunders, Philadelphia, pp 57–78 Waring W (1983) The history and physical examination. In: Kendig E, Chernick V (ed) Disorders of the repiratory tract in children. Saunders, Philadelphia, pp 57–78
16.
Zurück zum Zitat Network TARDS (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 342:1301–1308CrossRef Network TARDS (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 342:1301–1308CrossRef
17.
Zurück zum Zitat McDonald MJ, Montgomery VL, Cerrito PB, Parrish CJ, Boland KA, Sullivan JE (2002) Comparison of end-tidal CO2 and Paco2 in children receiving mechanical ventilation. Pediatr Crit Care Med 3:244–249PubMedCrossRef McDonald MJ, Montgomery VL, Cerrito PB, Parrish CJ, Boland KA, Sullivan JE (2002) Comparison of end-tidal CO2 and Paco2 in children receiving mechanical ventilation. Pediatr Crit Care Med 3:244–249PubMedCrossRef
18.
Zurück zum Zitat Rozycki HJ, Sysyn GD, Marshall MK, Malloy R, Wiswell TE (1998) Mainstream end-tidal carbon dioxide monitoring in the neonatal intensive care unit. Pediatrics 101:648–653PubMedCrossRef Rozycki HJ, Sysyn GD, Marshall MK, Malloy R, Wiswell TE (1998) Mainstream end-tidal carbon dioxide monitoring in the neonatal intensive care unit. Pediatrics 101:648–653PubMedCrossRef
19.
Zurück zum Zitat Tobias JD, Meyer DJ (1997) Noninvasive monitoring of carbon dioxide during respiratory failure in toddlers and infants: end-tidal versus transcutaneous carbon dioxide. Anesth Analg 85:55–58PubMedCrossRef Tobias JD, Meyer DJ (1997) Noninvasive monitoring of carbon dioxide during respiratory failure in toddlers and infants: end-tidal versus transcutaneous carbon dioxide. Anesth Analg 85:55–58PubMedCrossRef
Metadaten
Titel
Acceptable respiratory physiologic limits for children during weaning from mechanical ventilation
verfasst von
Miriam Santschi
France Gauvin
Georges Hatzakis
Jacques Lacroix
Philippe Jouvet
Publikationsdatum
01.02.2007
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 2/2007
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-006-0414-0

Weitere Artikel der Ausgabe 2/2007

Intensive Care Medicine 2/2007 Zur Ausgabe

Tipps für den Umgang mit Behandlungsfehlern

01.05.2024 DGIM 2024 Kongressbericht

Es ist nur eine Frage der Zeit, bis es zu einem Zwischenfall kommt und ein Behandlungsfehler passiert. Doch wenn Ärztinnen und Ärzte gut vorbereitet sind, schaffen es alle Beteiligten den Umständen entsprechend gut durch diese Krise. 

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.