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Intensive Care Medicine

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11.12.2017 | What's New in Intensive Care

Adjuvant therapies in critical care: steroids to treat infectious diseases

verfasst von: José Manuel Pereira, Thiago Lisboa, José-Artur Paiva

Erschienen in: Intensive Care Medicine | Ausgabe 8/2018

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Excerpt

Globally, clinicians have avoided prescribing corticosteroids (CS) for active infection, as they have immunosuppressive effects and therefore may impair mechanisms that fight infection. However, we, as intensivists, often see patients adequately treated with antibiotics deteriorating on the basis of progressive, localized or systemic inflammation triggered by an infection that is being treated with an adequate antibiotic regimen. Clinically, they have been proven as deleterious in some infectious diseases, such as influenza pneumonia, established for early use in a wide range of infective conditions, such as pneumococcal meningitis, and remain a matter of intense debate in several other infectious conditions, such as severe community-acquired pneumonia. …

Confalonieri M, Urbino R, Potena A et al (2005) Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study. Am J Respir Crit Care Med 171:242–248CrossRefPubMed

Garcia-Vidal C, Calbo E, Pascual V et al (2007) Effects of systemic steroids in patients with severe community-acquired pneumonia. Eur Respir J 30:951–956CrossRefPubMed

Nie W, Zhang Y, Cheng J, Xiu Q (2012) Corticosteroids in the treatment of community-acquired pneumonia in adults: a meta-analysis. PLoS One 7:e47926CrossRefPubMedPubMedCentral

Torres A, Sibila O, Ferrer M et al (2015) Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial. JAMA 313:677–686CrossRefPubMed

Tagami T, Matsui H, Horiguchi H et al (2015) Low-dose corticosteroid use and mortality in severe community-acquired pneumonia patients. Eur Respir J 45:463–472CrossRefPubMed

Siemieniuk RA, Meade MO, Alonso-Coello P et al (2015) Corticosteroid therapy for patients hospitalized with community-acquired pneumonia: a systematic review and meta-analysis. Ann Intern Med 163:519–528CrossRefPubMed

Marti C, Grosgurin O, Harbarth S et al (2015) Adjunctive corticotherapy for community acquired pneumonia: a systematic review and meta-analysis. PLoS One 10:e0144032CrossRefPubMedPubMedCentral

Horita N, Otsuka T, Haranaga S et al (2015) Adjunctive systemic corticosteroids for hospitalized community-acquired pneumonia: systematic review and meta-analysis 2015 update. Sci Rep 5:14061CrossRefPubMedPubMedCentral

Chen LP, Chen JH, Chen Y et al (2015) Efficacy and safety of glucocorticoids in the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials. World J Emerg Med 6:172–178CrossRefPubMedPubMedCentral

10.

Wan YD, Sun TW, Liu ZQ et al (2016) Efficacy and safety of corticosteroids for community-acquired pneumonia: a systematic review and meta-analysis. Chest 149:209–219CrossRefPubMed

11.

Briel M, Spoorenberg SMC, Snijders D et al (2017) Corticosteroids in patients hospitalized with community-acquired pneumonia: systematic review and individual patient data meta-analysis. Clin Infect Dis. https://doi.org/10.1093/cid/cix801 CrossRef

12.

Pastores SM, Annane D, Rochwerg B, The Corticosteroid Guideline Task Force of SCCM and ESICM (2017) Guidelines for the diagnosis of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part II): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. Intensive Care Med. https://doi.org/10.1007/s00134-017-4951-5 CrossRefPubMed

13.

Rodrigo C, Leonardi-Bee J, Nguyen-Van-Tam J, Lim WS (2016) Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858 PubMedCrossRef

14.

Cooley L, Dendle C, Wolf J et al (2014) Consensus guidelines for diagnosis, prophylaxis and management of Pneumocystis jirovecii pneumonia in patients with haematological and solid malignancies. Intern Med J 44(12b):1350–1363CrossRefPubMed

15.

Lemiale V, Debrumetz A, Delannoy et al (2013) Adjunctive steroid in HIV-negative patients with severe Pneumocystis pneumonia. Respir Res 14:87CrossRefPubMedPubMedCentral

16.

Hoffman SL, Punjabi NH, Kumala S et al (1984) Reduction of mortality in chloramphenicol-treated severe typhoid fever by high-dose dexamethasone. N Engl J Med 310(2):82–88CrossRefPubMed

17.

Rogerson SJ, Spooner VJ, Smith TA, Richens J (1991) Hydrocortisone in chloramphenicol-treated severe typhoid fever in Papua New Guinea. Trans R Soc Trop Med Hyg 85:113–116CrossRefPubMed

18.

Brouwer MC, McIntyre P, Prasad K, van de Beek D (2015) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.cd004405.pub5 CrossRefPubMed

19.

van de Beek D, Cabellos C, Dzupova O et al (2016) ESCMID guideline: diagnosis and treatment of acute bacterial meningitis. Clin Microbiol Infect 22(Suppl 3):S37–S62CrossRefPubMed

20.

de Gans J, van de Beek D, European Dexamethasone in Adulthood Bacterial Meningitis Study Investigators (2002) Dexamethasone in adults with bacterial meningitis. N Engl J Med 347(20):1549–1556CrossRefPubMed

21.

Prasad K, Singh MB, Ryan H (2016) Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.cd002244.pub4 PubMedPubMedCentralCrossRef

22.

Wiysonge CS, Ntsekhe M, Thabane L et al (2017) Interventions for treating tuberculous pericarditis. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.cd000526.pub2 CrossRefPubMedPubMedCentral

23.

Ryan H, Yoo J, Darsini P (2017) Corticosteroids for tuberculous pleurisy. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.cd001876.pub3 PubMedCentralCrossRefPubMed

24.

Sharma SK, Mohan A, Sharma A, Mitra DK (2005) Miliary tuberculosis: new insights into an old disease. Lancet Infect Dis 5(7):415–430CrossRefPubMed

Titel: Adjuvant therapies in critical care: steroids to treat infectious diseases
verfasst von: José Manuel Pereira
Thiago Lisboa
José-Artur Paiva
Publikationsdatum: 11.12.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 8/2018
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-5020-9

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Adjuvant therapies in critical care: steroids to treat infectious diseases

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