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Der Nervenarzt
Erschienen in: Der Nervenarzt 9/2012

01.09.2012 | Leitthema

Ätiopathogenetische Aspekte somatoformer Störungen

verfasst von: Dr. M. Noll-Hussong, H. Gündel

Erschienen in: Der Nervenarzt | Ausgabe 9/2012

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Zusammenfassung

Die Ätiopathologie somatoformer Störungen ist nur vor dem Hintergrund eines biopsychozialen Modells integriert darstellbar. Hierbei müssen kulturelle wie historische Einflüsse ebenso berücksichtigt werden wie die jeweils aktuell vorherrschende Schwerpunktsetzung in Forschung und Praxis. Vor diesem Hintergrund ist die Betonung neurobiologischer Befunde auch als das nicht zufällige Ringen von Betroffenen wie deren Behandlern um Legitimität zu interpretieren. Die Datenlage zu Einflussfaktoren auf Entstehung und Aufrechterhaltung somatoformen Geschehens ist ebenso divers wie weitgehend unspezifisch und weist damit auf ein noch abzuarbeitendes Forschungsprogramm hin.
Literatur
1.
2.
Aragona M, Pucci D, Carrer S et al (2011) The role of post-migration living difficulties on somatization among first-generation immigrants visited in a primary care service. Ann Ist Super Sanita 47:207–213PubMed
3.
Arbeitskreis Piso (2012) Somatoforme Störungen. Hogrefe, Göttingen
4.
Arnett SV, Alleva LM, Korossy-Horwood R et al (2011) Chronic fatigue syndrome – a neuroimmunological model. Med Hypotheses 77:77–83PubMedCrossRef
5.
Baiardini I, Abba S, Ballauri M et al (2011) Alexithymia and chronic diseases: the state of the art. G Ital Med Lav Ergon 33:A47–A52PubMed
6.
Barker C, Pistrang N, Shapiro DA et al (1990) Coping and help-seeking in the UK adult population. Br J Clin Psychol 29:271–285PubMedCrossRef
7.
Barsky AJ, Orav EJ, Ahern DK et al (1999) Somatic style and symptom reporting in rheumatoid arthritis. Psychosomatics 40:396–403PubMedCrossRef
8.
Barsky AJ, Orav EJ, Bates DW (2006) Distinctive patterns of medical care utilization in patients who somatize. Med Care 44:803–811PubMedCrossRef
9.
Bhatt A, Tomenson B, Benjamin S (1989) Transcultural patterns of somatization in primary care: a preliminary report. J Psychosom Res 33:671–680PubMedCrossRef
10.
Biggs AM, Aziz Q, Tomenson B et al (2003) Do childhood adversity and recent social stress predict health care use in patients presenting with upper abdominal or chest pain? Psychosom Med 65:1020–1028PubMedCrossRef
11.
Borkum JM (2010) Chronic headaches and the neurobiology of somatization. Curr Pain Headache Rep 14:55–61PubMedCrossRef
12.
Braun IM, Liang MH, Orav EJ et al (2008) A personality characteristic, somatic absorption, and the perception of somatic symptoms in rheumatoid arthritis patients. J Rheumatol 35:782–789PubMed
13.
Brendgen M, Vitaro F (2008) Peer rejection and physical health problems in early adolescence. J Dev Behav Pediatr 29:183–190PubMedCrossRef
14.
Briquet P (1859) Traité clinique et thérapeutique de l’hystérie. Baillière et Fils, Paris
15.
Browning M, Fletcher P, Sharpe M (2011) Can neuroimaging help us to understand and classify somatoform disorders? A systematic and critical review. Psychosom Med 73:173–184PubMedCrossRef
16.
Buddeberg-Fischer B, Klaghofer R, Reed V et al (2000) Psychosomatic health promotion in adolescents. An intervention study in 2 high schools. Gesundheitswesen 62:499–504PubMedCrossRef
17.
Buffington CA (2009) Developmental influences on medically unexplained symptoms. Psychother Psychosom 78:139–144PubMedCrossRef
18.
Cederblad M, Dahlin L, Hagnell O et al (1995) Intelligence and temperament as protective factors for mental health. A cross-sectional and prospective epidemiological study. Eur Arch Psychiatry Clin Neurosci 245:11–19PubMedCrossRef
19.
Ceko M, Bushnell MC, Gracely RH (2012) Neurobiology underlying fibromyalgia symptoms. Pain Res Treat 2012:585419PubMed
20.
Chaban V (2012) Estrogen and visceral nociception at the level of primary sensory neurons. Pain Res Treat 2012
21.
Chaturvedi SK, Desai G (2006) What’s ‚in the body‘ is actually ‚in the mind’! Int Rev Psychiatry 18:1–3PubMedCrossRef
22.
Cho HJ, Skowera A, Cleare A et al (2006) Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology. Curr Opin Psychiatry 19:67–73PubMedCrossRef
23.
Cicchetti D, Rogosch FA, Sturge-Apple ML (2007) Interactions of child maltreatment and serotonin transporter and monoamine oxidase A polymorphisms: depressive symptomatology among adolescents from low socioeconomic status backgrounds. Dev Psychopathol 19:1161–1180PubMed
24.
Ciccone DS, Just N, Bandilla EB (1999) A comparison of economic and social reward in patients with chronic nonmalignant back pain. Psychosom Med 61:552–563PubMed
25.
Claussen B, Bjorndal A, Hjort PF (1993) Health and re-employment in a 2 year follow up of long term unemployed. J Epidemiol Community Health 47:14–18PubMedCrossRef
26.
Cope H, David A, Mann A (1994) ‚Maybe it’s a virus?’: beliefs about viruses, symptom attributional style and psychological health. J Psychosom Res 38:89–98PubMedCrossRef
27.
Cope H, David A, Pelosi A et al (1994) Predictors of chronic „postviral“ fatigue. Lancet 344:864–868PubMedCrossRef
28.
Craig TK, Cox AD, Klein K (2002) Intergenerational transmission of somatization behaviour: a study of chronic somatizers and their children. Psychol Med 32:805–816PubMedCrossRef
29.
AWMF (2012) S3 Leitlinie „Umgang mit Patienten mit nicht-spezifischen, funktionellen und somatoformen Körperbeschwerden“. (Registernummer 051–001)
30.
Diatchenko L, Nackley AG, Slade GD et al (2006) Idiopathic pain disorders – pathways of vulnerability. Pain 123:226–230PubMedCrossRef
31.
Dimsdale JE, Dantzer R (2007) A biological substrate for somatoform disorders: importance of pathophysiology. Psychosom Med 69:850–854PubMedCrossRef
32.
Duddu V, Isaac MK, Chaturvedi SK (2006) Somatization, somatosensory amplification, attribution styles and illness behaviour: a review. Int Rev Psychiatry 18:25–33PubMedCrossRef
33.
Eber T, Chapman J, Shoenfeld Y (2005) Anti-ribosomal P-protein and its role in psychiatric manifestations of systemic lupus erythematosus: myth or reality? Lupus 14:571–575PubMedCrossRef
34.
Eimecke S, Pauschardt J, Remschmidt H et al (2011) Time trends in psychopathology. A 21-year comparison from Germany. Z Kinder Jugendpsychiatr Psychother 39:187–194PubMedCrossRef
35.
Eisenberger NI (2012) The neural bases of social pain: evidence for shared representations with physical pain. Psychosom Med 74:126–135PubMedCrossRef
36.
Elder GH Jr, Shanahan MJ, Clipp EC (1997) Linking combat and physical health: the legacy of World War II in men’s lives. Am J Psychiatry 154:330–336PubMed
37.
Fiddler M, Jackson J, Kapur N et al (2004) Childhood adversity and frequent medical consultations. Gen Hosp Psychiatry 26:367–377PubMedCrossRef
38.
Fink P, Schroder A (2010) One single diagnosis, bodily distress syndrome, succeeded to capture 10 diagnostic categories of functional somatic syndromes and somatoform disorders. J Psychosom Res 68:415–426PubMedCrossRef
39.
Garcia-Campayo J, Fayed N, Serrano-Blanco A et al (2009) Brain dysfunction behind functional symptoms: neuroimaging and somatoform, conversive, and dissociative disorders. Curr Opin Psychiatry 22:224–231PubMedCrossRef
40.
Ghorbani N, Cunningham CJ, Watson PJ (2010) Comparative analysis of integrative self-knowledge, mindfulness, and private self-consciousness in predicting responses to stress in Iran. Int J Psychol 45:147–154PubMedCrossRef
41.
Gil FP, Giegling I, Reisch N et al (2011) Association of somatoform disorder symptoms with genetic variants potentially involved in the modulation of nociception. Psychiatr Genet 21:50PubMedCrossRef
42.
Godin I, Kittel F (2004) Differential economic stability and psychosocial stress at work: associations with psychosomatic complaints and absenteeism. Soc Sci Med 58:1543–1553PubMedCrossRef
43.
Gundel H, Stadtland C, Huber D (2003) Assessment and psychotherapeutic options of patients with somatoform disorders and a claim for invalidity pensioning. Psychother Psychosom Med Psychol 53:250–257PubMedCrossRef
44.
Hanel G, Henningsen P, Herzog W et al (2009) Depression, anxiety, and somatoform disorders: vague or distinct categories in primary care? Results from a large cross-sectional study. J Psychosom Res 67:189–197PubMedCrossRef
45.
46.
Hennings A, Zill P, Rief W (2009) Serotonin transporter gene promoter polymorphism and somatoform symptoms. J Clin Psychiatry 70:1536–1539PubMedCrossRef
47.
Henningsen P, Zipfel S, Herzog W (2007) Management of functional somatic syndromes. Lancet 369:946–955PubMedCrossRef
48.
Hickie I, Davenport T, Wakefield D et al (2006) Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study. BMJ 333:575PubMedCrossRef
49.
Holliday KL, Macfarlane GJ, Nicholl BI et al (2010) Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. J Psychosom Res 68:469–474PubMedCrossRef
50.
Holliday KL, Mcbeth J (2011) Recent advances in the understanding of genetic susceptibility to chronic pain and somatic symptoms. Curr Rheumatol Rep 13:521–527PubMedCrossRef
51.
Hyphantis T, Tomenson B, Paika V et al (2009) Somatization is associated with physical health-related quality of life independent of anxiety and depression in cancer, glaucoma and rheumatological disorders. Qual Life Res 18:1029–1042PubMedCrossRef
52.
Janssens KA, Oldehinkel AJ, Dijkstra JK et al (2011) School absenteeism as a perpetuating factor of functional somatic symptoms in adolescents: the TRAILS study. J Pediatr 159:988–993, e981PubMedCrossRef
53.
Janssens KA, Oldehinkel AJ, Rosmalen JG (2009) Parental overprotection predicts the development of functional somatic symptoms in young adolescents. J Pediatr 154:918–923 e911PubMedCrossRef
54.
John U, Meyer C, Rumpf HJ et al (2004) Smoking, nicotine dependence and psychiatric comorbidity: a population-based study including smoking cessation after three years. Drug Alcohol Depend 76:287–295PubMedCrossRef
55.
Joksimovic L, Starke D, V D Knesebeck O et al (2002) Perceived work stress, overcommitment, and self-reported musculoskeletal pain: a cross-sectional investigation. Int J Behav Med 9:122–138PubMedCrossRef
56.
Kapfhammer HP, Rothenhausler HB (2004) Chronic fatigue syndrome. MMW Fortschr Med 146:29, 31–23PubMed
57.
Karantanos T, Markoutsaki T, Gazouli M et al (2010) Current insights in to the pathophysiology of Irritable Bowel Syndrome. Gut Pathog 2:3PubMedCrossRef
58.
Kennedy PJ, Clarke G, Quigley EM et al (2012) Gut memories: towards a cognitive neurobiology of irritable bowel syndrome. Neurosci Biobehav Rev 36:310–340PubMedCrossRef
59.
Kingma EM, Janssens KA, Venema M et al (2011) Adolescents with low intelligence are at risk of functional somatic symptoms: the TRAILS study. J Adolesc Health 49:621–626PubMedCrossRef
60.
Kingma EM, Tak LM, Huisman M et al (2009) Intelligence is negatively associated with the number of functional somatic symptoms. J Epidemiol Community Health 63:900–905PubMedCrossRef
61.
Kirmayer LJ, Looper KJ (2006) Abnormal illness behaviour: physiological, psychological and social dimensions of coping with distress. Curr Opin Psychiatry 19:54–60PubMedCrossRef
62.
Kirmayer LJ, Sartorius N (2007) Cultural models and somatic syndromes. Psychosom Med 69:832–840PubMedCrossRef
63.
Klose M, Jacobi F (2004) Can gender differences in the prevalence of mental disorders be explained by sociodemographic factors? Arch Womens Ment Health 7:133–148PubMedCrossRef
64.
Koh KB, Choi EH, Lee YJ et al (2011) Serotonin-related gene pathways associated with undifferentiated somatoform disorder. Psychiatry Res 189:246–250PubMedCrossRef
65.
Kolk AM, Hanewald GJ, Schagen S et al (2003) A symptom perception approach to common physical symptoms. Soc Sci Med 57:2343–2354PubMedCrossRef
66.
Kroenke K, Spitzer RL (1998) Gender differences in the reporting of physical and somatoform symptoms. Psychosom Med 60:150–155PubMed
67.
Laederach-Hofmann K, Ruddel H, Mussgay L (2008) Pathological baroreceptor sensitivity in patients suffering from somatization disorders: do they correlate with symptoms? Biol Psychol 79:243–249PubMedCrossRef
68.
Lahmann C, Henningsen P, Noll-Hussong M (2010) Somatoform pain disorder: overview. Psychiatr Danub 22:453–458PubMed
69.
Lahmann C, Henningsen P, Noll-Hussong M et al (2010) Somatoform disorders. Psychother Psychosom Med Psychol 60:227–233 (quiz 234)PubMedCrossRef
70.
Landmark-Hoyvik H, Reinertsen KV, Loge JH et al (2010) The genetics and epigenetics of fatigue. Pm R 2:456–465PubMedCrossRef
71.
Lee S (2001) From diversity to unity. The classification of mental disorders in 21st-century China. Psychiatr Clin North Am 24:421–431PubMedCrossRef
72.
Lieb R, Zimmermann P, Friis RH et al (2002) The natural course of DSM-IV somatoform disorders and syndromes among adolescents and young adults: a prospective-longitudinal community study. Eur Psychiatry 17:321–331PubMedCrossRef
73.
Liverman CS, Brown JW, Sandhir R et al (2009) Role of the oestrogen receptors GPR30 and ERalpha in peripheral sensitization: relevance to trigeminal pain disorders in women. Cephalalgia 29:729–741PubMedCrossRef
74.
Lombardi VC, Ruscetti FW, Das Gupta J et al (2009) Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science 326:585–589PubMedCrossRef
75.
Lowe B, Spitzer RL, Williams JB et al (2008) Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment. Gen Hosp Psychiatry 30:191–199PubMedCrossRef
76.
Maes M, Rief W (2012) Diagnostic classifications in depression and somatization should include biomarkers, such as disorders in the tryptophan catabolite (TRYCAT) pathway. Psychiatry Res 196:243–249PubMedCrossRef
77.
Mai FM, Merskey H (1980) Briquet’s treatise on hysteria. A synopsis and commentary. Arch Gen Psychiatry 37:1401–1405PubMedCrossRef
78.
Malinow KL, Molina R, Gordon B et al (1985) Neuropsychiatric dysfunction in primary Sjogren’s syndrome. Ann Intern Med 103:344–350PubMed
79.
Mayou R, Kirmayer LJ, Simon G et al (2005) Somatoform disorders: time for a new approach in DSM-V. Am J Psychiatry 162:847–855PubMedCrossRef
80.
Naliboff BD (2007) Towards a nondualistic approach to multisystem illness. Am J Gastroenterol 102:2777–2780PubMedCrossRef
81.
Nery FG, Borba EF, Viana VS et al (2008) Prevalence of depressive and anxiety disorders in systemic lupus erythematosus and their association with anti-ribosomal P antibodies. Prog Neuropsychopharmacol Biol Psychiatry 32:695–700PubMedCrossRef
82.
Ng BY (1999) Hysteria: a cross-cultural comparison of its origins and history. Hist Psychiatry 10:287–301PubMedCrossRef
83.
Nickel R, Hardt J, Kappis B et al (2009) Somatoform disorders with pain as the predominant symptom: results to distinguish a common group of diseases. Schmerz 23:392–398PubMedCrossRef
84.
Nijs J, Meeus M, Van Oosterwijck J et al (2011) Treatment of central sensitization in patients with ‚unexplained‘ chronic pain: what options do we have? Expert Opin Pharmacother 12:1087–1098PubMedCrossRef
85.
Noll-Hussong M, Gündel H, Lahmann C et al (2010) Somatoforme Störungen. In: Schiepek G (Hrsg) Neurobiologie der Psychotherapie. Schattauer, Stuttgart
86.
Noll-Hussong M, Otti A, Laeer L et al (2010) Aftermath of sexual abuse history on adult patients suffering from chronic functional pain syndromes: an fMRI pilot study. J Psychosom Res 68:483–487PubMedCrossRef
87.
Noyes R Jr, Stuart SP, Watson DB (2008) A reconceptualization of the somatoform disorders. Psychosomatics 49:14–22PubMedCrossRef
88.
O’toole BI, Catts SV, Outram S et al (2009) The physical and mental health of Australian Vietnam veterans 3 decades after the war and its relation to military service, combat, and post-traumatic stress disorder. Am J Epidemiol 170:318–330CrossRef
89.
Otti A, Guendel H, Laer L et al (2010) I know the pain you feel-how the human brain’s default mode predicts our resonance to another’s suffering. Neuroscience 169:143–148PubMedCrossRef
90.
Otti A, Gundel H, Wohlschlager A et al (2012) Default mode network of the brain. Neurobiology and clinical significance. Nervenarzt 83:16, 18–24PubMedCrossRef
91.
92.
Papelbaum M, Moreira RO, Gaya CW et al (2010) Impact of body mass index on the psychopathological profile of obese women. Rev Bras Psiquiatr 32:42–46PubMedCrossRef
93.
Pearce JM (2002) Psychosocial factors in chronic disability. Med Sci Monit 8:RA275–281PubMed
94.
Phillips K, Clauw DJ (2011) Central pain mechanisms in chronic pain states—maybe it is all in their head. Best Pract Res Clin Rheumatol 25:141–154PubMedCrossRef
95.
Rantala MA, Ahlberg J, Suvinen TI et al (2003) Temporomandibular joint related painless symptoms, orofacial pain, neck pain, headache, and psychosocial factors among non-patients. Acta Odontol Scand 61:217–222PubMedCrossRef
96.
Rees L (1959) The role of stress in the aetiology of psychosomatic disorders. Proc R Soc Med 52:274–278PubMed
97.
Rhee H, Holditch-Davis D, Miles MS (2005) Patterns of physical symptoms and relationships with psychosocial factors in adolescents. Psychosom Med 67:1006–1012PubMedCrossRef
98.
Rief W, Barsky AJ (2005) Psychobiological perspectives on somatoform disorders. Psychoneuroendocrinology 30:996–1002PubMedCrossRef
99.
Rief W, Broadbent E (2007) Explaining medically unexplained symptoms-models and mechanisms. Clin Psychol Rev 27:821–841PubMedCrossRef
100.
Ringel Y, Drossman DA, Leserman JL et al (2008) Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study. Gastroenterology 134:396–404PubMedCrossRef
101.
Ronel J, Noll-Hussong M, Lahmann C (2008) Von der Hysterie zur F45.0. Psychotherapie im Dialog 9
102.
Roy M, Shohamy D, Wager TD (2012) Ventromedial prefrontal-subcortical systems and the generation of affective meaning. Trends Cogn Sci 16:147–156PubMedCrossRef
103.
Sarzi-Puttini P, Atzeni F, Mease PJ (2011) Chronic widespread pain: from peripheral to central evolution. Best Pract Res Clin Rheumatol 25:133–139PubMedCrossRef
104.
Schaefer M, Egloff B, Witthoft M (2012) Is interoceptive awareness really altered in somatoform disorders? Testing competing theories with two paradigms of heartbeat perception. J Abnorm Psychol
105.
Schafer I, Hansen H, Schon G et al (2012) The influence of age, gender and socio-economic status on multimorbidity patterns in primary care. first results from the multicare cohort study. BMC Health Serv Res 12:89PubMedCrossRef
106.
Schneider G, Heuft G (2011) Medically unexplained and somatoform complaints and disorders in the elderly: a systematic review of the literature. Z Psychosom Med Psychother 57:115–140PubMed
107.
Schouler-Ocak M, Bretz HJ, Hauth I et al (2010) Patients of immigrant origin in outpatient psychiatric facilities: a comparison between Turkish, eastern European and German patients. Psychiatr Prax 37:384–390PubMedCrossRef
108.
Schwille-Kiuntke J, Enck P, Zendler C et al (2011) Postinfectious irritable bowel syndrome: follow-up of a patient cohort of confirmed cases of bacterial infection with Salmonella or Campylobacter. Neurogastroenterol Motil 23:e479–e488PubMedCrossRef
109.
Segal B, Bowman SJ, Fox PC et al (2009) Primary Sjogren’s syndrome: health experiences and predictors of health quality among patients in the United States. Health Qual Life Outcomes 7:46PubMedCrossRef
110.
Seminowicz DA, Wideman TH, Naso L et al (2011) Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function. J Neurosci 31:7540–7550PubMedCrossRef
111.
Shiroma PR, Alarcon RD (2011) Time for healing: somatization among chronically mentally ill immigrants. J Cult Divers 18:3–7PubMed
112.
Shorter E (1997) Somatization and chronic pain in historic perspective. Clin Orthop Relat Res:52–60CrossRef
113.
Simmons G, Glynn SA, Komaroff AL et al (2011) Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study. Science 334:814–817PubMedCrossRef
114.
Stein DJ, Muller J (2008) Cognitive-affective neuroscience of somatization disorder and functional somatic syndromes: reconceptualizing the triad of depression-anxiety-somatic symptoms. CNS Spectr 13:379–384PubMed
115.
Steinbrecher N, Koerber S, Frieser D et al (2011) The prevalence of medically unexplained symptoms in primary care. Psychosomatics 52:263–271PubMedCrossRef
116.
Stone J, Carson A, Sharpe M (2005) Functional symptoms in neurology: management. J Neurol Neurosurg Psychiatry 76(Suppl 1):13–21CrossRef
117.
Sturgeon JA, Zautra AJ (2010) Resilience: a new paradigm for adaptation to chronic pain. Curr Pain Headache Rep 14:105–112PubMedCrossRef
118.
Subic-Wrana C, Beutel ME, Knebel A et al (2010) Theory of mind and emotional awareness deficits in patients with somatoform disorders. Psychosom Med 72:404–411PubMedCrossRef
119.
Subic-Wrana C, Tschan R, Michal M et al (2011) Childhood trauma and its relation to diagnoses and psychic complaints in patients of an psychosomatic university ambulance. Psychother Psychosom Med Psychol 61:54–61PubMedCrossRef
120.
Tak LM, Bakker SJ, Slaets JP et al (2009) Is high-sensitive C-reactive protein a biomarker for functional somatic symptoms? A population-based study. Brain Behav Immun 23:1014–1019PubMedCrossRef
121.
Tak LM, Janssens KA, Dietrich A et al (2010) Age-specific associations between cardiac vagal activity and functional somatic symptoms: a population-based study. Psychother Psychosom 79:179–187PubMedCrossRef
122.
Tran MT, Arendt-Nielsen L, Kupers R et al (2012) Multiple chemical sensitivity: on the scent of central sensitization. Int J Hyg Environ Health
123.
Tschan R, Best C, Beutel ME et al (2011) Patients‘ psychological well-being and resilient coping protect from secondary somatoform vertigo and dizziness (SVD) 1 year after vestibular disease. J Neurol 258:104–112PubMedCrossRef
124.
Van Wijk CM, Kolk AM (1997) Sex differences in physical symptoms: the contribution of symptom perception theory. Soc Sci Med 45:231–246CrossRef
125.
Voigt K, Nagel A, Meyer B et al (2010) Towards positive diagnostic criteria: a systematic review of somatoform disorder diagnoses and suggestions for future classification. J Psychosom Res 68:403–414PubMedCrossRef
126.
Waller E, Scheidt CE, Hartmann A (2004) Attachment representation and illness behavior in somatoform disorders. J Nerv Ment Dis 192:200–209PubMedCrossRef
127.
Watts G (2012) Critics attack DSM-5 for overmedicalising normal human behaviour. BMJ 344:e1020PubMedCrossRef
128.
Wood JD, Liu S, Drossman DA et al (2012) Anti-enteric neuronal antibodies and the irritable bowel syndrome. J Neurogastroenterol Motil 18:78–85PubMedCrossRef
129.
Yiangou Y, Facer P, Chessell IP et al (2007) Voltage-gated ion channel Nav1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain). Neurosci Lett 427:77–82PubMedCrossRef
130.
Zebrack BJ, Zeltzer LK, Whitton J et al (2002) Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin’s disease, and non-Hodgkin’s lymphoma: a report from the Childhood Cancer Survivor Study. Pediatrics 110:42–52PubMedCrossRef
Metadaten
Titel
Ätiopathogenetische Aspekte somatoformer Störungen
verfasst von
Dr. M. Noll-Hussong
H. Gündel
Publikationsdatum
01.09.2012
Verlag
Springer-Verlag
Erschienen in
Der Nervenarzt / Ausgabe 9/2012
Print ISSN: 0028-2804
Elektronische ISSN: 1433-0407
DOI
https://doi.org/10.1007/s00115-011-3444-y

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