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Annals of Surgical Oncology

Ausgabe 13/2019

Inhalt (89 Artikel)

Health Services Research and Global Oncology

2019 SSO Presidential Address: Serendipity and Strategy on the Path of Progress

Armando E. Giuliano

Breast Oncology

Flipping a Coin? Predicting Nodal Status After Neoadjuvant Chemotherapy

Theresa Schwartz, Julie Margenthaler

Hepatobiliary Tumors

Radiomics: A Well-Intentioned Leap of Faith

Clifford S. Cho

Sarcoma

To Biopsy, or Not to Biopsy: Is There Really a Question?

Mark Fairweather, Chandrajit P. Raut

Translational Research and Biomarkers

Editorial: A Novel Monoclonal Antibody-Targeting Angiogenesis by Inhibiting Secreted Frizzled-Related Protein 2

Julie E. Lang, William W. Tseng, Irene Kang

Health Services Research and Global Oncology

Economic Analysis of Adjuvant Chemoradiotherapy Compared with Chemotherapy in Resected Pancreas Cancer

Nivethan Vela, Laura E. Davis, Stephanie Y. Cheng, Ahmed Hammad, Ying Liu, Daniel J. Kagedan, Lawrence Paszat, Lev D. Bubis, Craig C. Earle, Sten Myrehaug, Alyson L. Mahar, Nicole Mittmann, Natalie G. Coburn, Mina Siqqidui, Qing Li, Maryam Elmi, Elizabeth Shin, Eugene Hsieh, Nik Goyert

Health Services Research and Global Oncology

Deficits in the Palliative Care Process Measures in Patients with Advanced Pancreatic Cancer Undergoing Operative and Invasive Nonoperative Palliative Procedures

Brooks V. Udelsman, Elizabeth J. Lilley, Motaz Qadan, David C. Chang, Keith D. Lillemoe, Charlotta Lindvall, Zara Cooper

Health Services Research and Global Oncology

Comparative Age-Based Prospective Multi-Institutional Observations of 12,367 Patients Enrolled to the American College of Surgeons Oncology Group (ACOSOG) Z901101 Trials (Alliance)

Waddah B. Al-Refaie, Paul A. Decker, Karla V. Ballman, Peter W. T. Pisters, Mitchell C. Posner, Kelly K. Hunt, Bryan Meyers, Armin D. Weinberg, Heidi Nelson, Lisa Newman, Angelina Tan, Jennifer G. Le-Rademacher, Arti Hurria, Aminah Jatoi

Open Access Health Services Research and Global Oncology

Malignant Peritoneal Mesothelioma: Patterns of Care and Survival in the Netherlands: A Population-Based Study

Nadine L. de Boer, Job P. van Kooten, Ronald A. M. Damhuis, Joachim G. J. V. Aerts, Cornelis Verhoef, Eva V. E. Madsen

Health Services Research and Global Oncology

Risk of Dementia in Gastric Cancer Survivors Who Underwent Gastrectomy: A Nationwide Study in Korea

Yoon Jin Choi, Dong Wook Shin, Wooyoung Jang, Dong Ho Lee, Su-Min Jeong, Sanghyun Park, Kyung-do Han, Yong Gyu Park

Breast Oncology

Is Clinical Exam of the Axilla Sufficient to Select Node-Positive Patients Who Downstage After NAC for SLNB? A Comparison of the Accuracy of Clinical Exam Versus MRI

Tracy-Ann Moo, Maxine S. Jochelson, Emily C. Zabor, Michelle Stempel, Monica Raiss, Anita Mamtani, Audree B. Tadros, Mahmoud El-Tamer, Monica Morrow

Breast Oncology

Does Breast Density Increase the Risk of Re-excision for Women with Breast Cancer Having Breast-Conservation Therapy?

Siun M. Walsh, Sandra B. Brennan, Emily C. Zabor, Laura H. Rosenberger, Michelle Stempel, Lizza Lebron-Zapata, Mary L. Gemignani

Breast Oncology

Circumferential Shaving of the Cavity in Breast-Conserving Surgery: A Randomized Controlled Trial

Kai Chen, Liling Zhu, Lili Chen, Qian Li, Shunrong Li, Na Qiu, Yaping Yang, Fengxi Su, Erwei Song

Breast Oncology

Impact of Age on Locoregional and Distant Recurrence After Mastectomy for Ductal Carcinoma In Situ With or Without Microinvasion

Anita Mamtani, Faina Nakhlis, Stephanie Downs-Canner, Emily C. Zabor, Monica Morrow, Tari A. King, Kimberly J. Van Zee

Open Access Breast Oncology

Validation of Residual Cancer Burden as Prognostic Factor for Breast Cancer Patients After Neoadjuvant Therapy

Hannah Deborah Müller, Florian Posch, Christoph Suppan, Ute Bargfrieder, Melanie Gumpoldsberger, Robert Hammer, Hubert Hauser, Nadia Dandachi, Kurt Prein, Herbert Stoeger, Sigurd Lax, Marija Balic

Breast Oncology

Redefining Eligibility by Analyzing Canceled Intraoperative Radiotherapy as a Boost for Patients Undergoing Breast-Conserving Treatment

Jun Won Kim, Yeona Cho, Jinhyun Choi, Sung Gwe Ahn, Joon Jeong, Ik Jae Lee

Breast Oncology

A Nomogram to Predict Factors Associated with Lymph Node Metastasis in Ductal Carcinoma In Situ with Microinvasion

Jessica C. Gooch, Freya Schnabel, Jennifer Chun, Elizabeth Pirraglia, Andrea B. Troxel, Amber Guth, Richard Shapiro, Deborah Axelrod, Daniel Roses

Breast Oncology

Breast Cancer Found Incidentally After Reduction Mammaplasty in Young Insured Women

Kara Vande Walle, Dou-Yan Y. Yang, Trista J. Stankowski-Drengler, Devon Livingston-Rosanoff, Sara Fernandes-Taylor, Jessica R. Schumacher, Lee G. Wilke, Caprice C. Greenberg, Heather B. Neuman

Breast Oncology

Risk of Contralateral Breast Cancer in Women with Ductal Carcinoma In Situ Associated with Synchronous Ipsilateral Lobular Carcinoma In Situ

Megan E. Miller, Shirin Muhsen, Emily C. Zabor, Jessica Flynn, Cristina Olcese, Dilip Giri, Kimberly J. Van Zee, Melissa Pilewskie

Breast Oncology

Patterns of Axillary Management in Stages 2 and 3 Hormone Receptor-Positive Breast Cancer by Initial Treatment Approach

Anna Weiss, Stephanie Wong, Mehra Golshan, Rachel A. Freedman, Otto Metzger, Jennifer Bellon, Elizabeth A. Mittendorf, Tari A. King

Breast Oncology

Axillary Lymph Node Ultrasound Following Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: Results from the SN FNAC Study

Dominique Morency, Sinziana Dumitra, Elena Parvez, Karyne Martel, Mark Basik, André Robidoux, Brigitte Poirier, Claire M. B. Holloway, Louis Gaboury, Lucas Sideris, Sarkis Meterissian, Jean-François Boileau

Breast Oncology

Trends in Regional Nodal Management of Breast Cancer Patients with Low Nodal Burden

Benjamin M. Raber, Heather Lin, Yu Shen, Simona F. Shaitelman, Isabelle Bedrosian

Open Access Breast Oncology

Impact of Second Opinions in Breast Cancer Diagnostics and Treatment: A Retrospective Analysis

E. Heeg, Y. A. Civil, M. A. Hillen, C. H. Smorenburg, L. A. E. Woerdeman, E. J. Groen, H. A. O. Winter-Warnars, M. T. F. D. Vrancken Peeters

Breast Oncology

Challenges in Clinical Trial Implementation: Results from a Survey of the National Accreditation Program of Breast Centers (NAPBC)

Anna Weiss, Nicole E. Lopez, Erin P. Ward, Katherine C. Lee, Abigail S. Caudle, Diana Dickson-Witmer, Cecilia Chang, Kaitlyn Kelly, Linda Williams Martin, Lisa Kay Jacobs, Kelly K. Hunt, Katherine Yao, Sarah L. Blair

Breast Oncology

An In-Visit Decision Aid for Surgeons to Address Decision Making for Bilateral Mastectomy for Newly Diagnosed Breast Cancer Patients

Katharine Yao, Jeff Belkora, Clara Lee, Kristine Kuchta, Catherine Pesce, Katherine Kopkash, Sarah Rabbitt, Ermilo Barrera, Sandra Simovic, Karen Sepucha

Breast Oncology

Heterogeneous Responses of Axillary Lymph Node Metastases to Neoadjuvant Chemotherapy are Common and Depend on Breast Cancer Subtype

Antonia Glaeser, Hans-Peter Sinn, Carlos Garcia-Etienne, Fabian Riedel, Sarah Hug, Benedikt Schaefgen, Michael Golatta, Andre Hennigs, Manuel Feisst, Christof Sohn, Joerg Heil

Colorectal Cancer

Safety of Single-Site Laparoscopic Surgery Requiring Perioperative Heparinization in Colorectal Cancer: Propensity Score-Matched Analysis

Kazuya Iwamoto, Hidekazu Takahashi, Makoto Fujii, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Masaki Mori, Doki Yuichiro

Open Access Colorectal Cancer

The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer

Hester C. van Wyk, Antonia Roseweir, Peter Alexander, James H. Park, Paul G. Horgan, Donald C. McMillan, Joanne Edwards

Endocrine Tumors

Comparing the Utility and Surgical Outcomes of Harmonic Focus Ultrasonic Scalpel with Ligasure Small Jaw Bipolar Device in Thyroidectomies: A Prospective Randomized Controlled Trial

Shen-Han Lee, Thien Khanh Nguyen, Whee-Sze Ong, Benjamin Haaland, Gerald Ci-An Tay, Ngian Chye Tan, Hiang Khoon Tan, Jeremy Chung Fai Ng, N. Gopalakrishna Iyer

Endocrine Tumors

Long-Term Oncologic Outcomes After Curative Resection of Familial Medullary Thyroid Carcinoma

Philip M. Spanheimer, Ian Ganly, Joanne Chou, Marinela Capanu, Ronald A. Ghossein, R. Michael Tuttle, Richard J. Wong, Ashok R. Shaha, Brian R. Untch

Endocrine Tumors

A Novel N Staging System for Predicting Survival in Patients with Medullary Thyroid Cancer

Lili Chen, Kai Qian, Kai Guo, Xiaoke Zheng, Wenyu Sun, Tuanqi Sun, Yunjun Wang, Duanshu Li, Yi Wu, Qinghai Ji, Zhuoying Wang

Endocrine Tumors

Preoperative Computed Tomography Changes Surgical Management for Clinically Low-Risk Well-Differentiated Thyroid Cancer

Pim J. Bongers, Raoul Verzijl, Michael Dzingala, Menno R. Vriens, Eugene Yu, Jesse D. Pasternak, Lorne E. Rotstein

Gastrointestinal Oncology

Comparison of Tissue and Blood Concentrations of Oxaliplatin Administrated by Different Modalities of Intraperitoneal Chemotherapy

Urs Giger-Pabst, Petru Bucur, Sébastien Roger, Thomas Albert Falkenstein, Nicolas Tabchouri, Alain Le Pape, Stéphanie Lerondel, Cédric Demtröder, Ephrem Salamé, Mehdi Ouaissi

Gastrointestinal Oncology

Curative-Intent Surgery for Stage IV Advanced Gastric Cancer: Who Can Undergo Surgery and What Are the Prognostic Factors for Long-Term Survival?

Sho Sato, Chikara Kunisaki, Yusaku Tanaka, Kei Sato, Hiroshi Miyamoto, Norio Yukawa, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo, Toshihiro Misumi

Head and Neck Oncology

Clinical Significance of Gross Invasion of Strap Muscles in Patients With 1- to 4-cm-Sized Papillary Thyroid Carcinoma Undergoing Lobectomy

Eyun Song, Won Woong Kim, Min Ji Jeon, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Ki Wook Chung, Won Bae Kim, Young Kee Shong, Suck Joon Hong, Yu-Mi Lee, Won Gu Kim

Head and Neck Oncology

The First Human Trial of Transoral Robotic Surgery Using a Single-Port Robotic System in the Treatment of Laryngo-Pharyngeal Cancer

Young Min Park, Da Hee Kim, Min Seok Kang, Jae Yol Lim, Eun Chang Choi, Yoon Woo Koh, Se-Heon Kim

Head and Neck Oncology

Sentinel Node Biopsy in 105 High-Risk Cutaneous SCCs of the Head and Neck: Results of a Multicenter Prospective Study

Craig P. Mooney, Richard C. W. Martin, Richard Dirven, Bruce G. Ashford, Kerwin Shannon, Carsten E. Palme, Quan Ngo, James Wykes, Sarah Davies, Kan Gao, Sydney Ch’ng, Tsu-Hui Low, Ruta Gupta, Jonathan R. Clark

Pancreatic Tumors

Perioperative Gemcitabine + Erlotinib Plus Pancreaticoduodenectomy for Resectable Pancreatic Adenocarcinoma: ACOSOG Z5041 (Alliance) Phase II Trial

Alice C. Wei, Fang-Shu Ou, Qian Shi, Xiomara Carrero, Eileen M. O’Reilly, Jeffrey Meyerhardt, Robert A. Wolff, Hedy L. Kindler, Douglas B. Evans, Vikram Deshpande, Joseph Misdraji, Eric Tamm, Dushyant Sahani, Malcolm Moore, Elliot Newman, Nipun Merchant, Jordan Berlin, Laura W. Goff, Peter Pisters, Mitchell C. Posner

Pancreatic Tumors

A Prospective, Open-Label, Multicenter Phase 2 Trial of Neoadjuvant Therapy Using Full-Dose Gemcitabine and S-1 Concurrent with Radiation for Resectable Pancreatic Ductal Adenocarcinoma

Hidetoshi Eguchi, Yutaka Takeda, Hidenori Takahashi, Shin Nakahira, Masaki Kashiwazaki, Junzo Shimizu, Daisuke Sakai, Fumiaki Isohashi, Hiroaki Nagano, Masaki Mori, Yuichiro Doki

Pancreatic Tumors

MiR-194-5p in Pancreatic Ductal Adenocarcinoma Peritoneal Washings is Associated with Peritoneal Recurrence and Overall Survival in Peritoneal Cytology-Negative Patients

Hirokazu Kubo, Yukihiko Hiroshima, Ryutaro Mori, Yusuke Saigusa, Takashi Murakami, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Takafumi Kumamoto, Ryusei Matsuyama, Itaru Endo

Pancreatic Tumors

Management of Acute Cholecystitis during Neoadjuvant Therapy in Patients with Pancreatic Adenocarcinoma

Neil R. Jariwalla, Abdul H. Khan, Kulwinder Dua, Kathleen K. Christians, Callisia N. Clarke, Mohammed Aldakkak, Ben George, Sean Tutton, William Rilling, Beth Erickson, Douglas B. Evans, Susan Tsai

Hepatobiliary Tumors

Preoperative Radiomic Approach to Evaluate Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma Patients Using Contrast-Enhanced Computed Tomography

Haotian Liao, Zhen Zhang, Jie Chen, Mingheng Liao, Lin Xu, Zhenru Wu, Kefei Yuan, Bin Song, Yong Zeng

Hepatobiliary Tumors

Severe Preoperative Symptoms Delay Readiness to Return to Intended Oncologic Therapy (RIOT) After Liver Resection

Heather A. Lillemoe, Rebecca K. Marcus, Bradford J. Kim, Nisha Narula, Catherine H. Davis, Qiuling Shi, Xin Shelley Wang, Thomas A. Aloia

Open Access Hepatobiliary Tumors

Prognostic Relevance of a Complete Pathologic Response in Liver Transplantation for Hepatocellular Carcinoma

Michał Grąt, Marek Krawczyk, Jan Stypułkowski, Marcin Morawski, Maciej Krasnodębski, Michał Wasilewicz, Zbigniew Lewandowski, Karolina Grąt, Waldemar Patkowski, Krzysztof Zieniewicz

Hepatobiliary Tumors

The Achievement of a Sustained Virological Response Either Before or After Hepatectomy Improves the Prognosis of Patients with Primary Hepatitis C Virus-Related Hepatocellular Carcinoma

Yukiyasu Okamura, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Katsuhiko Uesaka

Hepatobiliary Tumors

Laparoscopic Parenchymal-Sparing Hepatectomy for Multiple Colorectal Liver Metastases Improves Outcomes and Salvageability: A Propensity Score-Matched Analysis

Shinya Okumura, Nicolas Tabchouri, Universe Leung, Pascale Tinguely, Christophe Louvet, Marc Beaussier, Brice Gayet, David Fuks

Hepatobiliary Tumors

Prediction of Histopathologic Growth Patterns of Colorectal Liver Metastases with a Noninvasive Imaging Method

Jin Cheng, Jingwei Wei, Tong Tong, Weiqi Sheng, Yinli Zhang, Yuqi Han, Dongsheng Gu, Nan Hong, Yingjiang Ye, Jie Tian, Yi Wang

Open Access Hepatobiliary Tumors

Adjuvant Hepatic Arterial Infusion Pump Chemotherapy After Resection of Colorectal Liver Metastases: Results of a Safety and Feasibility Study in The Netherlands

Florian E. Buisman, Dirk J. Grünhagen, Marjolein Y. V. Homs, Cecile Grootscholten, Wills F. Filipe, Nancy E. Kemeny, Andrea Cercek, Micheal I. D’Angelica, Maarten L. Donswijk, Leni van Doorn, Jasper Emmering, William R. Jarnagin, T. Peter Kingham, Elisabeth G. Klompenhouwer, Niels F. M. Kok, Maria C. Kuiper, Adriaan Moelker, Warner Prevoo, Michelle W. J. Versleijen, Cornelis Verhoef, Koert F. D. Kuhlmann, Bas Groot Koerkamp

Melanoma

Impact of Effective Systemic Therapy on Metastasectomy in Stage IV Melanoma: A Matched-Pair Analysis

Daniel W. Nelson, Trevan D. Fischer, Amanda N. Graff-Baker, Ahmed Dehal, Stacey Stern, Anton J. Bilchik, Mark B. Faries

Melanoma

Survival Outcomes of Patients with Clinical Stage III Melanoma in the Era of Novel Systemic Therapies

Yun Song, Andrew D. Tieniber, Phyllis A. Gimotty, Tara C. Mitchell, Ravi K. Amaravadi, Lynn M. Schuchter, Douglas L. Fraker, Giorgos C. Karakousis

Melanoma

Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size

Sabran J. Masoud, Janice B. Hu, Georgia M. Beasley, John H. Stewart IV, Paul J. Mosca

Melanoma

Squamous Cell Carcinoma with Regional Metastasis to Axilla or Groin Lymph Nodes: a Multicenter Outcome Analysis

George Pang, Nicole J. Look Hong, Gabrielle Paull, Johanna Dobransky, Suzana Kupper, Scott Hurton, Daniel J. Kagedan, May Lynn Quan, Lucy Helyer, Carolyn Nessim, Frances C. Wright

Melanoma

Practice Patterns and Prognostic Value of Sentinel Lymph Node Biopsy for Thick Melanoma: A National Cancer Database Study

Yun Song, Feredun S. Azari, Daniel Aryeh Metzger, Douglas L. Fraker, Giorgos C. Karakousis

Melanoma

Inguinal and Ilio-inguinal Lymphadenectomy in Management of Palpable Melanoma Lymph Node Metastasis: A Long-Term Prospective Evaluation of Morbidity and Quality of Life

Michael A. Henderson, D. Gyorki, B. H. Burmeister, J. Ainslie, R. Fisher, J. Di Iulio, B. M. Smithers, A. Hong, K. Shannon, R. A. Scolyer, S. Carruthers, B. J. Coventry, S. Babington, J. Duprat, H. J. Hoekstra, J. F. Thompson

Melanoma

The Prognosis and Natural History of In-Transit Melanoma Metastases at a High-Volume Centre

Emilia Nan Tie, Lumine H. Na, Rodney J. Hicks, John Spillane, David Speakman, Michael A. Henderson, David E. Gyorki

Reconstructive Oncology

Postoperative Cancer Surveillance Following Oncoplastic Surgery with Latissimus Dorsi Flap: a Matched Case–Control Study

Kenneth L. Fan, Simon Yang, Seho Park, Tae Hwan Park, Seung Yong Song, Nara Lee, Dae Hyun Lew, Min Jung Kim, Dong Won Lee

Sarcoma

Early and Late Complications of Percutaneous Core Needle Biopsy of Retroperitoneal Tumors at Two Tertiary Sarcoma Centers

David Berger-Richardson, Sally M. Burtenshaw, Andrea M. Ibrahim, Rebecca A. Gladdy, Rebecca Auer, Rob Beecroft, Brendan C. Dickson, Bibianna Purgina, Kristin Ambacher, Carolyn Nessim, Carol J. Swallow

Sarcoma

Outcome of Primary Desmoid Tumors at All Anatomic Locations Initially Managed with Active Surveillance

Winan J. van Houdt, Olga Husson, Alisha Patel, Robin L. Jones, Myles J. F. Smith, Aisha B. Miah, Christina Messiou, Eleonor Moskovic, Omar Al-Muderis, Charlotte Benson, Shane Zaidi, Alison Dunlop, Dirk C. Strauss, Andrew J. Hayes, Winette T. A. van der Graaf

Open Access Sarcoma

Functional Outcome Measurement in Patients with Lower-Extremity Soft Tissue Sarcoma: A Systematic Literature Review

Gilber Kask, Ian Barner-Rasmussen, Jussi Petteri Repo, Magnus Kjäldman, Kaarel Kilk, Carl Blomqvist, Erkki Juhani Tukiainen

Sarcoma

The Prognostic Value of Lymphovascular Invasion in Truncal and Extremity Soft Tissue Sarcomas: An Analysis from the National Cancer Database

Cecilia G. Ethun, Alexandra G. Lopez-Aguiar, Jeffery M. Switchenko, Theresa W. Gillespie, Keith A. Delman, Charles A. Staley, Shishir K. Maithel, Kenneth Cardona

Sarcoma

Is Peritoneal Tumor Penetration of Prognostic Importance in Gastrointestinal Stromal Tumors?

T. Hølmebakk, B. Bjerkehagen, I. V. K. Lobmaier, I. Hompland, S. Stoldt, K. Boye

Thoracic Oncology

Clinical Implications of Conversion Surgery After Induction Therapy for T4b Thoracic Esophageal Squamous Cell Carcinoma

Hiroshi Miyata, Keijirou Sugimura, Masaaki Motoori, Takeshi Omori, Kazuyoshi Yamamoto, Yoshitomo Yanagimoto, Naoki Shinno, Masayoshi Yasui, Hidenori Takahashi, Hiroshi Wada, Masayuki Ohue, Masahiko Yano

Thoracic Oncology

The Influence of the Perioperative Nutritional Status on the Survival Outcomes for Esophageal Cancer Patients with Neoadjuvant Chemotherapy

Makoto Hikage, Yusuke Taniyama, Tadashi Sakurai, Chiaki Sato, Kai Takaya, Hiroshi Okamoto, Takuro Konno, Naoto Ujiie, Takeshi Naitoh, Michiaki Unno, Takashi Kamei

Thoracic Oncology

Dysphagia Score as a Predictor of Adverse Events Due to Triplet Chemotherapy and Oncological Outcomes in 434 Consecutive Patients with Esophageal Cancer

Takaomi Hagi, Tomoki Makino, Makoto Yamasaki, Koji Tanaka, Naohiro Nishida, Daisuke Sakai, Masaaki Motoori, Yutaka Kimura, Taroh Satoh, Masaki Mori, Yuichiro Doki

Open Access Thoracic Oncology

Quality of Life During and After Completion of Neoadjuvant Chemoradiotherapy for Esophageal and Junctional Cancer

B. J. Noordman, M. G. E. Verdam, B. Onstenk, J. Heisterkamp, W. J. B. M. Jansen, I. S. Martijnse, S. M. Lagarde, B. P. L. Wijnhoven, C. M. M. Acosta, A. van der Gaast, M. A. G. Sprangers, J. J. B. van Lanschot

Thoracic Oncology

Modified Systemic Inflammation Score is Useful for Risk Stratification After Radical Resection of Squamous Cell Carcinoma of the Esophagus

Mitsuro Kanda, Masahiko Koike, Chie Tanaka, Daisuke Kobayashi, Norifumi Hattori, Masamichi Hayashi, Suguru Yamada, Kenji Omae, Michitaka Fujiwara, Yasuhiro Kodera

Translational Research and Biomarkers

Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo

Denise Garcia, Patrick Nasarre, Ingrid V. Bonilla, Eleanor Hilliard, Yuri K. Peterson, Laura Spruill, Anne-Marie Broome, Elizabeth G. Hill, Jason T. Yustein, Shikhar Mehrotra, Nancy Klauber-DeMore

Translational Research and Biomarkers

Vimentin Expression in Tumor Microenvironment Predicts Survival in Pancreatic Ductal Adenocarcinoma: Heterogeneity in Fibroblast Population

Hiromitsu Maehira, Toru Miyake, Hiroya Iida, Aya Tokuda, Haruki Mori, Daiki Yasukawa, Ken-ichi Mukaisho, Tomoharu Shimizu, Masaji Tani

Translational Research and Biomarkers

Association Between Preoperative Muscle Mass and Intraoperative Bacterial Translocation in Patients Undergoing Hepatectomy, Pancreatoduodenectomy, and Esophagectomy

Kumiko Akashi, Yukihiro Yokoyama, Takashi Mizuno, Tetsuya Abe, Masahide Fukaya, Takashi Asahara, Masato Nagino

Translational Research and Biomarkers

Comprehensive Exploration to Identify Predictive DNA Markers of ΔNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma

Yosuke Ooizumi, Keita Kojima, Kazuharu Igarashi, Yoko Tanaka, Hiroki Harada, Kazuko Yokota, Takeshi Kaida, Satoru Ishii, Toshimichi Tanaka, Keigo Yokoi, Nobuyuki Nishizawa, Marie Washio, Hideki Ushiku, Hiroshi Katoh, Yoshimasa Kosaka, Hiroaki Mieno, Kei Hosoda, Masahiko Watanabe, Chikatoshi Katada, Naoki Hiki, Keishi Yamashita

Translational Research and Biomarkers

WiNTRLINC1/ASCL2/c-Myc Axis Characteristics of Colon Cancer with Differentiated Histology at Young Onset and Essential for Cell Viability

Kazuko Yokota, Yoko Tanaka, Hiroki Harada, Takeshi Kaida, Syuji Nakamoto, Takafumi Soeno, Yoshiki Fujiyama, Mitsuo Yokota, Ken Kojo, Hirohisa Miura, Takahiro Yamanashi, Takeo Sato, Takatoshi Nakamura, Masahiko Watanabe, Keishi Yamashita

Open Access Translational Research and Biomarkers

Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases

Malin Enblad, Wilhelm Graf, Alexei Terman, Pascal Pucholt, Björn Viklund, Anders Isaksson, Helgi Birgisson

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

23.04.2024 Ablationstherapie Nachrichten

Nach der Katheterablation von Vorhofflimmern kommt es bei etwa einem Drittel der Patienten zu Rezidiven, meist binnen eines Jahres. Wie sich spätere Rückfälle auf die Erfolgschancen einer erneuten Ablation auswirken, haben Schweizer Kardiologen erforscht.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

23.04.2024 Operationsvorbereitung Nachrichten

Derzeit wird empfohlen, eine Therapie mit GLP-1-Rezeptoragonisten präoperativ zu unterbrechen. Eine neue Studie nährt jedoch Zweifel an der Notwendigkeit der Maßnahme.

Ureterstriktur: Innovative OP-Technik bewährt sich

19.04.2024 EAU 2024 Kongressbericht

Die Ureterstriktur ist eine relativ seltene Komplikation, trotzdem bedarf sie einer differenzierten Versorgung. In komplexen Fällen wird dies durch die roboterassistierte OP-Technik gewährleistet. Erste Resultate ermutigen.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.