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Intensive Care Medicine

Erschienen in:

07.06.2018 | Editorial

Antipathy against SDD is justified: Yes

verfasst von: Jean-François Timsit, Matteo Bassetti

Erschienen in: Intensive Care Medicine | Ausgabe 7/2018

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In his Nobel Prize lecture in 1945, Fleming pointed out the easiness of making microbes resistant to penicillin “by exposing them to concentrations not sufficient to kill them”. In a famous lecture [1], Rice generalized this finding and concluded that the most reasonable strategy to minimize resistance is to “stop irritating the bacteria: (1) before therapy begins by treating only patients who are truly infected; (2) during therapy, avoiding the use of combination therapy when a single agent will suffice; (3) at the tail end of therapy, by treating only for as long as is required to cure the infection.” …

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Titel: Antipathy against SDD is justified: Yes
verfasst von: Jean-François Timsit
Matteo Bassetti
Publikationsdatum: 07.06.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 7/2018
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-018-5183-z

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