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Current Psychiatry Reports

Erschienen in:

01.12.2013 | Personality Disorders (C Schmahl, Section Editor)

Antisocial Personality Disorder: A Current Review

verfasst von: Andrea L. Glenn, Alexandria K. Johnson, Adrian Raine

Erschienen in: Current Psychiatry Reports | Ausgabe 12/2013

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Abstract

The Diagnostic and Statistical Manual of Mental Disorders (DSM 5) classification of antisocial personality disorder (ASPD) describes individuals who engage in repetitive irresponsible, delinquent, and criminal behavior. The diagnosis is highly controversial, with many researchers and clinicians arguing that the category is too heterogeneous, overinclusive, and demonstrates considerable overlap with other disorders. This review focuses on recent studies that have improved our understanding of the characteristics of individuals who fit the ASPD definition by exploring how subtypes differ and how comorbid conditions influence the presentation of ASPD. In addition, we discuss research on the etiology of ASPD that has identified genetic and environmental factors that may contribute to the development and persistence of antisocial behavior, and brain imaging research that has improved our understanding of the relationships between ASPD and other psychopathology. Finally, we discuss promising preliminary research on treatment for this disorder.

Gibbon S, Duggan C, Stoffers J, Huband N, Vollm BA, Ferriter M, et al. Psychological interventions for antisocial personality disorder. Cochrane Database Syst Rev. 2010;6, CD007668. doi:10.1002/14651858.CD007668.pub2.PubMed

Fazel S, Danesh J. Serious mental disorder in 23000 prisoners: a systematic review of 62 surveys. Lancet. 2002;359(9306):545–50. doi:10.1016/s0140-6736(02)07740-1.PubMedCrossRef

Ogloff JR. Psychopathy/antisocial personality disorder conundrum. Aust NZ J Psychiatry. 2006;40(6–7):519–28. doi:10.1111/j.1440-1614.2006.01834.x.CrossRef

Hare RD. Hare Psychopathy Checklist-Revised (PCL-R): 2nd Edition. Toronto: Multi-Health Systems, Inc.; 2003.

Patrick CJ, Fowles DC, Krueger RF. Triarchic conceptualization of psychopathy: Developmental origins of disinhibition, boldness, and meanness. Dev Psychopathol. 2009;21(Special Issue 03):913–38. doi:10.1017/S0954579409000492.PubMedCrossRef

Poythress NG, Edens JF, Skeem JL, Lilienfeld SO, Douglas KS, Frick PJ, et al. Identifying subtypes among offenders with antisocial personality disorder: a cluster-analytic study. J Abnorm Psychol. 2010;119(2):389–400. doi:10.1037/a0018611.PubMedCrossRef

Magyar MS, Edens JF, Lilienfeld SO, Douglas KS, Poythress Jr NG. Examining the relationship among substance abuse, negative emotionality and impulsivity across subtypes of antisocial and psychopathic substance abusers. J Crim Justice. 2011;39(3):232–7. doi:10.1016/j.jcrimjus.2011.02.013.CrossRef

Cox J, Edens JF, Magyar MS, Lilienfeld SO, Douglas KS, Poythress Jr NG. Using the Psychopathic Personality Inventory to identify subtypes of antisocial personality disorder. Journal of Criminal Justice. 2013;41(2):125–34. doi:10.1016/j.jcrimjus.2012.12.001.CrossRef

Lilienfeld SO, Andrews BP. Development and preliminary validation of a self-report measure of psychopathic personality traits in noncriminal populations. J Pers Assess. 1996;66:488–524.PubMedCrossRef

10.

Anton ME, Baskin-Sommers AR, Vitale JE, Curtin JJ, Newman JP. Differential effects of psychopathy and antisocial personality disorder symptoms on cognitive and fear processing in female offenders. Cogn Affect Behav Neurosci. 2012;12(4):761–76. doi:10.3758/s13415-012-0114-x.PubMedCrossRef

11.

Drislane LE, Vaidyanathan U, Patrick CJ. Reduced cortical call to arms differentiates psychopathy from antisocial personality disorder. Psychol Med. 2013;43(04):825–35. doi:10.1017/S0033291712001547.PubMedCrossRef

12.

• Gregory S, Ffytche D, Simmons A, Kumari V, Howard M, Hodgins S, et al. The antisocial brain: psychopathy matters. Arch Gen Psychiatry. 2012;69(9):962–72. doi:10.1001/archgenpsychiatry.2012.222. This study demonstrates the importance of including information about psychopathic traits in studies examining ASPD. The authors find reductions in gray matter only in offenders with ASPD and psychopathic traits.PubMedCrossRef

13.

• Hodgins S, De Brito SA, Chhabra P, Cote G. Anxiety disorders among offenders with antisocial personality disorders: a distinct subtype? Can J Psychiatr Rev Can Psychiatr. 2010;55(12):784–91. Although it was previously thought that anxiety limited criminal activity, this study reports that two-thirds of prisoners with ASPD present with a lifetime anxiety disorder. This suggests that anxiety is more prevalent than previously thought, and suggests that treatments may benefit from considering the role of anxiety in the development of aggressive behavior.

14.

DeShong HL, Kurtz JE. Four factors of impulsivity differentiate antisocial and borderline personality disorders. J Pers Disord. 2013;27(2):144–56. doi:10.1521/pedi.2013.27.2.144.PubMedCrossRef

15.

Whiteside SP, Lynam DR. The Five Factor Model and impulsivity: using a structural model of personality to understand impulsivity. Pers Individ Differ. 2001;30(4):669–89. doi:10.1016/S0191-8869(00)00064-7.CrossRef

16.

Swann AC, Lijffijt M, Lane SD, Steinberg JL, Moeller FG. Interactions between bipolar disorder and antisocial personality disorder in trait impulsivity and severity of illness. Acta Psychiatr Scand. 2010;121(6):453–61. doi:10.1111/j.1600-0447.2009.01528.x.PubMedCrossRef

17.

Mueser KT, Gottlieb JD, Cather C, Glynn SM, Zarate R, Smith LF, et al. Antisocial Personality Disorder in People with Co-Occurring Severe Mental Illness and Substance Use Disorders: Clinical, Functional, and Family Relationship Correlates. Psychosis. 2012;4(1):52–62. doi:10.1080/17522439.2011.639901.PubMedCrossRef

18.

Regier DA, Farmer ME, Rae DS, Locke BZ, Keith SJ, Judd LL, et al. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA J Am Med Assoc. 1990;264(19):2511–8.CrossRef

19.

Chavez JX. Assessing the incidence rates of substance use disorders among those with antisocial and borderline personality disorders in rural settings. Int J Psychol. 2010;2010(6):57–66.

20.

Sylvers P, Landfield KE, Lilienfeld SO. Heavy episodic drinking in college students: associations with features of psychopathy and antisocial personality disorder. J Am Coll Health J ACH. 2011;59(5):367–72. doi:10.1080/07448481.2010.511363.CrossRef

21.

Schiffer B, Muller BW, Scherbaum N, Hodgins S, Forsting M, Wiltfang J, et al. Disentangling structural brain alterations associated with violent behavior from those associated with substance use disorders. Arch Gen Psychiatry. 2011;68(10):1039–49. doi:10.1001/archgenpsychiatry.2011.61.PubMedCrossRef

22.

Moffitt TE. The new look of behavioral genetics in developmental psychopathology: Gene-environment interplay in antisocial behaviors. Psychol Bull. 2005;131:533–54.PubMedCrossRef

23.

Ferguson CJ. Genetic contributions to antisocial personality and behavior: a meta-analytic review from an evolutionary perspective. J Soc Psychol. 2010;150(2):160–80. doi:10.1080/00224540903366503.PubMedCrossRef

24.

• Barnes JC, Beaver KM, Boutwell BB. Examining the genetic underpinnings to Moffitt’s developmental taxonomy: A behavioral genetic analysis. Criminology. 2011;49(4):923–54. doi:10.1111/j.1745-9125.2011.00243.x. This study examines sibling pairs and finds that genetic factors explain more of the variance in being classified as a life-course persistent offender than as an adolescent-limited offender. This highlights the idea that these two groups have different underlying etiologies.CrossRef

25.

Moffitt TE. Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev. 1993;100(4):674–701.PubMedCrossRef

26.

Ducci F, Enoch MA, Hodgkinson C, Xu K, Catena M, Robin RW, et al. Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women. Mol Psychiatry. 2007;13:334–47. http://www.nature.com/mp/journal/v13/n3/suppinfo/4002034s1.html.PubMedCrossRef

27.

Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, et al. Role of genotype in the cycle of violence in maltreated children. Science. 2002;297:851–4.PubMedCrossRef

28.

Ponce G, Jimenez-Arriero MA, Rubio G, Hoenicka J, Ampuero I, Ramos JA, et al. The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients. Eur Psychiatry. 2003;18(7):356–60. doi:10.1016/j.eurpsy.2003.06.006.PubMedCrossRef

29.

Basoglu C, Oner O, Ates A, Algul A, Bez Y, Cetin M, et al. Synaptosomal-associated protein 25 gene polymorphisms and antisocial personality disorder: association with temperament and psychopathy. Can J Psychiatr Rev Can Psychiatr. 2011;56(6):341–7.

30.

Lesch K-P, Bengel D, Heils A, Sabol SZ, Greenberg B, Petri S, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274:1527–31.PubMedCrossRef

31.

Roberts AL, Gilman SE, Fitzmaurice G, Decker MR, Koenen KC. Witness of intimate partner violence in childhood and perpetration of intimate partner violence in adulthood. Epidemiology (Cambridge, Mass). 2010;21(6):809–18. doi:10.1097/EDE.0b013e3181f39f03.CrossRef

32.

Berg-Nielsen TS, Wichstrom L. The mental health of preschoolers in a Norwegian population-based study when their parents have symptoms of borderline, antisocial, and narcissistic personality disorders: at the mercy of unpredictability. Child Adolesc Psychiatry Mental health. 2012;6(1):19. doi:10.1186/1753-2000-6-19.CrossRef

33.

Herndon RW, Iacono WG. Psychiatric disorder in the children of antisocial parents. Psychol Med. 2005;35(12):1815–24. doi:10.1017/s0033291705005635.PubMedCrossRef

34.

Robertson LA, McAnally HM, Hancox RJ. Childhood and Adolescent Television Viewing and Antisocial Behavior in Early Adulthood. Pediatrics. 2013. doi:10.1542/peds.2012-1582.

35.

Shi Z, Bureau JF, Easterbrooks MA, Zhao X, Lyons-Ruth K. Childhood Maltreatment and Prospectively Observed Quality of Early Care as Predictors of Antisocial Personality Disorder Features. Infant Ment Health J. 2012;33(1):55–96. doi:10.1002/imhj.20295.PubMedCrossRef

36.

Liu N, Zhang Y, Brady HJ, Cao Y, He Y, Zhang Y. Relation between childhood maltreatment and severe intrafamilial male-perpetrated physical violence in Chinese community: the mediating role of borderline and antisocial personality disorder features. Aggress Behav. 2011. doi:10.1002/ab.20417.PubMed

37.

Kumari V, Gudjonsson GH, Raghuvanshi S, Barkataki I, Taylor P, Sumich A, et al. Reduced thalamic volume in men with antisocial personality disorder or schizophrenia and a history of serious violence and childhood abuse. Eur Psychiatr J Assoc Eur Psychiatr. 2013;28(4):225–34. doi:10.1016/j.eurpsy.2012.03.002.CrossRef

38.

Moffitt TE, Caspi A, Harrington H, Milne BJ. Males on the life-course-persistent and adolescence-limited antisocial pathways: follow-up at age 26 years. Dev Psychopathol. 2002;14(1):179–207.PubMedCrossRef

39.

Glenn AL, Yang Y, Raine A. Neuroimaging in psychopathy and antisocial personality disorder: Functional significance and a neurodevelopmental hypothesis. In: Simpson J, editor. Neuroimaging in Forensic Psychiatry. Oxford: Wiley-Blackwell; 2012.

40.

Yang Y, Raine A. Prefrontal structural and functional brain imaging findings in antisocial, violent, and psychopathic individuals: a meta-analysis. Psychiatry Res. 2009;174:81–8.PubMedCrossRef

41.

• Raine A, Yang Y, Narr KL, Toga AW. Sex differences in orbitofrontal gray as a partial explanation for sex differences in antisocial personality. Mol Psychiatry. 2011;16(2):227–36. doi:10.1038/mp.2009.136. This study proposes a potential explanation for the large gender difference in antisocial behavior – the gender difference in the size of the orbitofrontal cortex, which is smaller in males. Controlling for size of the orbitofrontal cortex reduced the gender difference in antisocial personality by 77.3%.PubMedCrossRef

42.

Krueger RF, Hicks BM, Patrick CJ, Carlson SR, Iacono WG, McGue M. Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrum. J Abnorm Psychol. 2002;111(3):411–24.PubMedCrossRef

43.

Tang Y, Jiang W, Liao J, Wang W, Luo A. Identifying Individuals with Antisocial Personality Disorder Using Resting-State fMRI. Plos One. 2013;8(4):e60652. doi:10.1371/journal.pone.0060652.PubMedCrossRef

44.

Jiang W, Liu H, Liao J, Ma X, Rong P, Tang Y, et al. A functional MRI study of deception among offenders with antisocial personality disorders. Neuroscience. 2013;244:90–8. doi:10.1016/j.neuroscience.2013.03.055.PubMedCrossRef

45.

Davidson KM, Tyrer P, Tata P, Cooke D, Gumley A, Ford I, et al. Cognitive behaviour therapy for violent men with antisocial personality disorder in the community: an exploratory randomized controlled trial. Psychol Med. 2009;39(4):569–77. doi:10.1017/s0033291708004066.PubMedCrossRef

46.

Bateman AW, Fonagy P. The structure of mentalization based treatment. In: Bateman AW, Fonagy P, editors. Mentalization-based treatment for borderline personality disorder. Oxford: Oxford University Press; 2006. p. 37–59.CrossRef

47.

McGauley G, Yakeley J, Williams A, Bateman A. Attachment, mentalization and antisocial personality disorder: The possible contribution of mentalization-based treatment. Eur J Psychother Couns. 2011;13(4):371–93. doi:10.1080/13642537.2011.629118.CrossRef

Titel: Antisocial Personality Disorder: A Current Review
verfasst von: Andrea L. Glenn
Alexandria K. Johnson
Adrian Raine
Publikationsdatum: 01.12.2013
Verlag: Springer US
Erschienen in: Current Psychiatry Reports / Ausgabe 12/2013
Print ISSN: 1523-3812
Elektronische ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-013-0427-7

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