Erschienen in:
01.07.2014 | Editorial
Candidemia and non-candidemia related septic shock: are there differences between them?
verfasst von:
Marin H. Kollef, José-Artur Paiva, Pierre-Emmanuel Charles
Erschienen in:
Intensive Care Medicine
|
Ausgabe 7/2014
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Excerpt
In a recent issue of
Intensive Care Medicine, Bassetti and colleagues [
1] evaluated 216 patients with septic shock attributable to
Candida bloodstream infection from five teaching hospitals in Italy and Spain. Overall, 116 patients (53.7 %) died within 30 days from the onset of
Candida bloodstream infection. Multivariate logistic regression analysis demonstrated that inadequate source control, inadequate antifungal therapy, and increasing severity of illness measured by APACHE II scores were independently associated with greater 30-day mortality. Initial treatment was considered adequate if the infecting organism was susceptible to the prescribed antimicrobial regimen and the dosage of antifungal used was adequate within the first 24 h from culture positivity. …