Introduction
The piriformis muscle is clinically well known for the compression of the sciatic nerve, the piriformis (muscle) syndrome or deep gluteal syndrome [11].
Related on this pathology, a vast amount of studies investigated the relationship between the piriformis muscle and the sciatic nerve, reporting the variability of the piriformis muscle mainly according to the classification by Beaton and Anson [3]. None of these studies reported an absent or missing piriformis muscle (e.g. [18]). Also fetal studies found a constant piriformis muscle (e.g. [2]).
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The literature provides only few reports on a missing piriformis muscle. Alexander Macalister found one case and reported this very case at least three times (e.g. Ref. [9]). Furthermore, Macalister cites case reports by Otto and Budge: in the subject dissected by Budge the lower limb was deformed [9], and in the specimen dissected by Otto the gemellus superior was very large [9]. These last observations are not sufficiently known for us to judge whether it was actually a real absence of the piriformis muscle or simply the fusion with one of the neighboring muscles, such as the gemellus superior or the gluteus medius muscles. The extensive compilation on anatomical variations of the piriformis muscle by Nicholson et al. [12] reports erroneously a paper, which should have described two missing piriformis muscles out of six specimens; nevertheless, that paper [5] describes six piriformis muscles in six specimens, whereas the gemellus superior was missing in two, and the gemellus inferior in one case.
Case report
We report here the case of a 60-year old Caucasian woman who died from amyotrophic lateral sclerosis. She donated her body to the anatomical department giving informed consent for using her body for scientific and educational purposes prior to death [14]. At admission a 30 cm scar was found at the left lateral thigh, and another 10 cm transversal collar scar. No further medical data are available. Her corpse was preserved using an arterial injection of a formaldehyde–phenol solution and immersed in phenolic acid in water for 3 months [13].
The corpse was used for a surgical-anatomical study on the superficial and subfascial vascularity of the gluteal region. When dissecting the right side and detaching the gluteus maximus muscle to display the gluteal arteries and veins no piriformis muscle could be found.
Description
The greater sciatic foramen is properly formed by the greater sciatic notch, the sacrotuberal and the sacrospinal ligaments. Only neurovascular structures pass, a common gluteal artery (replacing the superior gluteal artery), a superior gluteal vein, the sciatic nerve, an inferior gluteal vein, a (bipartite) pudendal nerve and the internal pudendal vessels. In other words, the piriformis muscle is missing as well as the inferior gluteal artery. Both, a vessel resembling the ‘descending branch of the inferior gluteal artery’ and the artery to the sciatic nerve originate from the common gluteal artery. Furthermore, at the lesser sciatic foramen, a quite large gemellus superior muscle accompanies the obturator internus muscle, whereas the gemellus inferior muscle is also missing (Fig. 1).
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The left side shows no variations; the piriformis muscle exists.
Fig. 1
Right deep gluteal region with absent piriformis muscle (female, 60 years)
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Discussion
As this case seems to be the second ‘verified’ throughout literature we have to discuss carefully possible probabilities such as (complete) fusion with another muscle, the (complete) involution or atrophy due to a medical intervention, or a real aplasia.
Fusion with another muscle
The piriformis muscle might fuse more or less completely with the gluteus medius, the gluteus minimus or the gemellus superior muscles, respectively. None of these is the case here.
Involution due to a medical intervention
Medical interventions for the treatment of piriformis muscle syndrome include methods such as botulinum toxin injections [1], surgical or endoscopic transection, i.e., tenotomy [8], or rupture during total hip arthroplasty [15]. Al-Al-Shaikh et al. [1] showed that tenotomy of the piriformis muscle leads to atrophy and fatty infiltration, but not to a complete disappearance. Furthermore, other authors argue that tenotomy might even increase the symptoms of piriformis muscle syndrome (post-tenotomy sciatica) due to retraction of the piriformis muscle [17].
Real aplasia
This is the most probable reason.
Clinical relevance
The piriformis muscle is an anatomical landmark for ultrasound investigations and ultrasound-guided interventions in the deep gluteal region such as a superior gluteal nerve block or even a sacral plexus block. Furthermore, the piriformis muscle is an important guide for any posterior surgical approach such as total hip arthroplasty. A missing piriformis muscle therefore affects the orientation in the deep gluteal region and therefore the identification of the targeted structures. Of course, the diagnosis of a piriformis syndrome and related interventions would be obsolete in a further patient with an absent piriformis muscle.
Comparative anatomy
In all hominoids the piriformis originates from the anterior surface of the sacrum, as well as from its lateral aspect, and inserts onto the greater trochanter of the femur [7]. In Babirusas, also called deer-pigs, this muscle has fused completely with the M. gluteus medius [10]. The piriformis of human anatomy differs in origin from that of the elephant, where it arises dorso-laterally from the sacral vertebrae close to the tuber sacrale of the ilium, and blends both with the superficial and middle glutei [6]. Based on the literature, the piriformis muscle is absent in several vertebrates, such as solipeds, ruminants, porks, macaques, spider monkeys, coati, bats, etc. [16]. The deep gluteal anlage, i.e., the gluteus medius, gluteus minimus and piriformis, is clearly homologous to the lizard iliofemoralis because in both groups this anlage has an acetabular bony origin, a proximal insertion, and a position posterior to the fibular nerve trunk [4].
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Acknowledgements
Open access funding provided by University of Innsbruck and Medical University of Innsbruck. The authors wish to thank this individual who donated her body and tissues for the advancement of education and research. We gratefully acknowledge the careful photographic documentation of the reported variation by Romed Hörmann, Division of Clinical and Functional Anatomy, Medical University of Innsbruck.
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