Ausgabe 5/2023
Inhalt (23 Artikel)
Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancer
- Review
Gayatri Patel, Tejas Girish Agnihotri, Manoj Gitte, Tanuja Shinde, Shyam Sudhakar Gomte, Roshan Goswami, Aakanchha Jain
The therapeutic potential of exosomes in lung cancer
- Review
Hongyuan Liang, Lingyun Zhang, Xiangxuan Zhao, Jian Rong
MAP3K1 expression is associated with progression and poor prognosis of hormone receptor-positive, HER2-negative early-stage breast cancer
- Original Article
Sung-Hsin Kuo, Ming-Feng Wei, Yi-Hsuan Lee, Jui-Chueh Lin, Wen-Chi Yang, Shi-Yi Yang, Chiun-Sheng Huang
DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis
- Research
Tianyu Feng, Siqi Li, Gang Zhao, Qin Li, Hang Yuan, Jie Zhang, Rui Gu, Deqiong Ou, Yafei Guo, Qiming Kou, Qijing Wang, Kai Li, Ping Lin
Comprehensive analysis of clinical prognostic features and tumor microenvironment landscape of CD11b+CD64+ patients with acute myeloid leukemia
- Research
Qian Wang, Nan Zhang, Li Liu, Linlu Ma, Yuxin Tan, Xiaoyan Liu, Jinxian Wu, Guopeng Chen, Xinqi Li, Yuxing Liang, Fuling Zhou
TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner
- Research
Xinyu Jiang, Wenfei Du, Chenglong Yang, Shuying Wang, Yifei Li, Xinzhuang Shen, Xiaowen Yang, Jie Yao, Renle Du, Xiaoyuan Zhang, Yongming Huang, Wenzhi Shen
SYVN1 ubiquitinates FoxO1 to induce β-catenin nuclear translocation, PD-L1-mediated metastasis, and immune evasion of hepatocellular carcinoma
- Open Access
- Research
Wei Xie, Lei Shi, Hu Quan, Hua Xiao, Jie Chen, Jia Liu, Jean de Dieu Habimana, Rongqi Huang, Jia Luo, Pan Chen, Zhiyuan Li
Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia
- Open Access
- Research
Kun-Chi Chen, I-Hsin Hsiao, Yu-Nan Huang, Yu-Tung Chou, Yi-Chun Lin, Ju-Yi Hsieh, Yung-Lung Chang, Kang-Hsi Wu, Guang-Yaw Liu, Hui-Chih Hung
PAQR5 inhibits the growth and metastasis of clear cell renal cell carcinoma by suppressing the JAK/STAT3 signaling pathway
- Research
Lu Wang, Yangyang Yue, Lu Zhang, Minxuan Jing, Minghai Ma, Chao Liu, Yan Li, Shan Xu, Ke Wang, Xinyang Wang, Jinhai Fan, Mengzhao Zhang
Aberrant expression of circular RNA DHPR facilitates tumor growth and metastasis by regulating the RASGEF1B/RAS/MAPK axis in hepatocellular carcinoma
- Research
Zeyi Guo, Qingyu Xie, Yanping Wu, Haiyu Mo, Jiajun Zhang, Guolin He, Zhongzhe Li, Luxiang Gan, Lei Feng, Ting Li, Yi Wang, Yu Fu, Lei Cai, Shao Li, Chao Yu, Yi Gao, Mingxin Pan, Shunjun Fu
Dissecting the single-cell transcriptome network of macrophage and identifies a signature to predict prognosis in lung adenocarcinoma
- Research
Zhengyang Hu, Xing Jin, Weifeng Hong, Qihai Sui, Mengnan Zhao, Yiwei Huang, Ming Li, Qun Wang, Cheng Zhan, Zhencong Chen
Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells
- Open Access
- Research
Lin Li, Xiaoyan Hu, Jewel Nkwocha, Kanika Sharma, Maciej Kmieciak, Hashim Mann, Liang Zhou, Steven Grant
A novel pyroptosis-associated lncRNA LINC01133 promotes pancreatic adenocarcinoma development via miR-30b-5p/SIRT1 axis
- Open Access
- Research
Jingwei Li, Jiewei Lin, Yuchen Ji, Xuelong Wang, Da Fu, Weishen Wang, Baiyong Shen
RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST
- Research
Man-Hon Chung, Rehanguli Aimaier, Qingxiong Yu, Haibo Li, Yuehua Li, Chengjiang Wei, Yihui Gu, Wei Wang, Zizhen Guo, Manmei Long, Qingfeng Li, Zhichao Wang
Single-cell RNA sequencing reveals the cellular and molecular characteristics of high-grade and metastatic bladder cancer
- Research
Yue Zheng, Xin Wang, Xiaofeng Yang, Nianzeng Xing
MAOA suppresses the growth of gastric cancer by interacting with NDRG1 and regulating the Warburg effect through the PI3K/AKT/mTOR pathway
- Research
Yang-Yang Wang, Yao-Qi Zhou, Jia-Xuan Xie, Xiang Zhang, Shu-Chang Wang, Qing Li, Li-Peng Hu, Shu-Heng Jiang, Shuang-Qin Yi, Jia Xu, Hui Cao, En-Hao Zhao, Jun Li
Repurposing ketotifen as a therapeutic strategy for neuroendocrine prostate cancer by targeting the IL-6/STAT3 pathway
- Research
Yiyi Ji, Bo Liu, Lei Chen, Ang Li, Kai Shen, Ruopeng Su, Weiwei Zhang, Yinjie Zhu, Qi Wang, Wei Xue
Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer
- Research
Tiezhu Shi, Zhihao Yuan, Yanying He, Dongliang Zhang, Siteng Chen, Xiongjun Wang, Linli Yao, Jialiang Shao, Xiang Wang
Transglutaminases are oncogenic biomarkers in human cancers and therapeutic targeting of TGM2 blocks chemoresistance and macrophage infiltration in pancreatic cancer
- Research
Shan Zhang, Hong-Fei Yao, Hui Li, Tong Su, Shu-Heng Jiang, Hao Wang, Zhi-Gang Zhang, Fang-Yuan Dong, Qin Yang, Xiao-Mei Yang
TRIM17-mediated ubiquitination and degradation of RBM38 promotes cisplatin resistance in non-small cell lung cancer
- Research
Tian Zhong, Jing Zhang, Xingren Liu, Hongmin Li
LncRNA MIR4435-2HG drives cancer progression by modulating cell cycle regulators and mTOR signaling in stroma-enriched subtypes of urothelial carcinoma of the bladder
- Open Access
- Research
Lu Pei, Dong Yan, Qingqing He, Jianqiu Kong, Meihua Yang, Honglian Ruan, Qiongqiong Lin, Lifang Huang, Jian Huang, Tianxin Lin, Haide Qin
METTL3 suppresses pancreatic ductal adenocarcinoma progression through activating endogenous dsRNA-induced anti-tumor immunity
- Research
Lili Zhu, Botai Li, Rongkun Li, Lipeng Hu, Yanli Zhang, Zhigang Zhang, Shuheng Jiang, Xueli Zhang
Correction to: CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation
- Open Access
- Correction
Javier Frontiñán-Rubio, Emilio Llanos-González, Sonia García-Carpintero, Juan Ramón Peinado, Inmaculada Ballesteros-Yáñez, Margarita Villar Rayo, José de la Fuente, Víctor M. Pérez-García, Luis A. Perez-Romasanta, Marcos Malumbres, Francisco J. Alcaín, Mario Durán-Prado
