Ausgabe 6/2022
Inhalt (25 Artikel)
Molecular actions of exosomes and their theragnostics in colorectal cancer: current findings and limitations
Wen-Chun Lin, Chun-Chi Lin, Yen-Yu Lin, Wen-Hao Yang, Yuh-Ching Twu, Hao-Wei Teng, Wei-Lun Hwang
Applications and mechanisms of the cyclin-dependent kinase 4/6 inhibitor, PD-0332991, in solid tumors
Wenjian Chen, Wencheng Zhang, Miaomiao Chen, Chao Yang, Ting Fang, Haifeng Wang, Lola M. Reid, Zhiying He
Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy
Elham Patrad, Solmaz Khalighfard, Taghi Amiriani, Vahid Khori, Ali Mohammad Alizadeh
Contribution of mechanical homeostasis to epithelial-mesenchymal transition
Se Jik Han, Sangwoo Kwon, Kyung Sook Kim
Role of nerves in neurofibromatosis type 1-related nervous system tumors
Ling-Ling Ge, Ming-Yan Xing, Hai-Bing Zhang, Qing-Feng Li, Zhi-Chao Wang
Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution
Guanglong Chen, Ting Gong, Zhe Wang, Zeyu Wang, Xiaolin Lin, Sunrui Chen, Chu Sun, Weijie Zhao, Ye Kong, Huihan Ai, Hang Yang, Yusheng Liu, Fangyan Wu, Jiawei Kang, Shasha Zhao, Xiuying Xiao, Jing Sun, Aina He, Zhi Li
Correction to: Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution
Guanglong Chen, Ting Gong, Zhe Wang, Zeyu Wang, Xiaolin Lin, Sunrui Chen, Chu Sun, Weijie Zhao, Ye Kong, Huihan Ai, Hang Yang, Yusheng Liu, Fangyan Wu, Jiawei Kang, Shasha Zhao, Xiuying Xiao, Jing Sun, Aina He, Zhi Li
Presence of regulatory T-cells in endometrial cancer predicts poorer overall survival and promotes progression of tumor cells
Thomas Kolben, Mareike Mannewitz, Carolin Perleberg, Konstantin Schnell, David Anz, Laura Hahn, Sarah Meister, Elisa Schmoeckel, Alexander Burges, Bastian Czogalla, Anna Hester, Sven Mahner, Mirjana Kessler, Udo Jeschke, Stefanie Corradini, Fabian Trillsch, Susanne Beyer
DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2
Jiaqi Sun, Xiyang Wang, Qingsong Shen, Min Wang, Shuxian Chen, Xuechun Zhang, Yongping Huang, Zhonglin Zhang, Wenhua Li, Yufeng Yuan, Zan Huang
Inhibition of PP2A by LB100 sensitizes bladder cancer cells to chemotherapy by inducing p21 degradation
Song Gao, Liping Shan, Mo Zhang, Yan Wang, Xi Zhan, Yalei Yin, Zhonghao Jiang, Xinyi Tao, Xinyu Li, Mingliang Ye, Yang Liu
CEP55 3’-UTR promotes epithelial–mesenchymal transition and enhances tumorigenicity of bladder cancer cells by acting as a ceRNA regulating miR-497-5p
Chenglin Yang, Yue Yang, Wei Wang, Wuer Zhou, Xiaoming Zhang, Yuansong Xiao, Huifen Zhang
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis
Michela Pasello, Anna Maria Giudice, Camilla Cristalli, Maria Cristina Manara, Caterina Mancarella, Alessandro Parra, Massimo Serra, Giovanna Magagnoli, Florencia Cidre-Aranaz, Thomas G. P. Grünewald, Carla Bini, Pier-Luigi Lollini, Alessandra Longhi, Davide Maria Donati, Katia Scotlandi
Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis
Michela Pasello, Anna Maria Giudice, Camilla Cristalli, Maria Cristina Manara, Caterina Mancarella, Alessandro Parra, Massimo Serra, Giovanna Magagnoli, Florencia Cidre-Aranaz, Thomas G. P. Grünewald, Carla Bini, Pier-Luigi Lollini, Alessandra Longhi, Davide Maria Donati, Katia Scotlandi
OSW-1 induces apoptosis and cyto-protective autophagy, and synergizes with chemotherapy on triple negative breast cancer metastasis
Mengling Wu, Qianrui Huang, Mengya Liao, Xuyi Wu, Huizhi Xi, Hongbo Ma, Shanrui Li, Yiwen Zhang, Yong Xia
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma
Ashley M. Fuller, Ann DeVine, Ileana Murazzi, Nicola J. Mason, Kristy Weber, T. S. Karin Eisinger-Mathason
Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8+T cells
Biaolong Yang, Biaolong Deng, Xiao-Dong Jiao, Bao-Dong Qin, Yi Lu, Weiqi Zhang, Yixian Guo, Shiqi Chen, Dan Li, Bin Li, Yuan-Sheng Zang
Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming
Yunjian Wu, Kimberley C. Clark, Elizabeth V. Nguyen, Birunthi Niranjan, Lisa G. Horvath, Renea A. Taylor, Roger J. Daly
Low SP1 SUMOylation-dependent SNHG17 upregulation promotes drug resistance of gastric cancer through impairing hsa-miR-23b-3p-induced Notch2 inhibition
Guoyu Huang, Guohao Cai, Dongwei Hu, Jinjie Li, Qigang Xu, Zongjing Chen, Bo Xu
Blockade of USP14 potentiates type I interferon signaling and radiation-induced antitumor immunity via preventing IRF3 deubiquitination
Weijian Wu, Huiying Xu, Chenyang Liao, Youqiao Wang, Ruirui Wu, Jiaxin Wu, Wenlv Zheng, Yunzhi Li, Chaoying Jin, Yuxuan Zhao, Junmin Quan, Xin Yue, Xianzhang Bu
Distinct tumor microenvironment landscapes of rectal cancer for prognosis and prediction of immunotherapy response
Fanqin Bu, Yu Zhao, Yushan Zhao, Xiaohan Yang, Lan Sun, Yang Chen, Shengtao Zhu, Li Min
FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis
Yiwei Huang, Guangyao Shan, Yanjun Yi, Jiaqi Liang, Zhengyang Hu, Guoshu Bi, Zhencong Chen, Junjie Xi, Di Ge, Qun Wang, Lijie Tan, Wei Jiang, Cheng Zhan
Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
Fabrice Viol, Bence Sipos, Martina Fahl, Till S. Clauditz, Tania Amin, Malte Kriegs, Maike Nieser, Jakob R. Izbicki, Samuel Huber, Ansgar W. Lohse, Jörg Schrader
ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation
Junpeng Meng, Hongkun Cai, Yan Sun, Shuang Wen, Heshui Wu, Dianyun Ren
The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth
Gao Liu, Zhang-Fu Yang, Jian Sun, Bao-Ye Sun, Pei-Yun Zhou, Cheng Zhou, Ruo-Yu Guan, Zhu-Tao Wang, Yong Yi, Shuang-Jian Qiu
Distinct expression and function of breast cancer metastasis suppressor 1 in mutant P53 glioblastoma
Deepak Babu, Ramulu Chintal, Manas Panigrahi, Prakash Babu Phanithi