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Head and Neck Pathology

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01.03.2010 | Case Report

Collagenous Myofibroblastic Tumor of the Mandible: Case Report of a Unique Locally Aggressive Neoplasm

verfasst von: Jason W. Nash, Amy C. Hessel, Nadarajah Vigneswaran, Adel K. El-Naggar

Erschienen in: Head and Neck Pathology | Ausgabe 1/2010

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Abstract

We report a locally aggressive collagenous myofibroblastic neoplasm of the mandible in an 18-year-old male. Clinically, the lesion presented with rapid growth and irregular mandibular bone destruction. Grossly, the tumor was 10 cm in greatest dimension, light-tan, firm, and involving the posterior one-thirds of the body and inferior half of the left mandibular ramus. Histologically, the lesion was composed of a loose spindle cell proliferation interspersed with periodic dense bands of collagen. The spindle cells reacted positively to smooth muscle actin, calponin, and focally to desmin and were negative for S-100, pan-cytokeratin, CD99, CD34 and caldesmon, supporting myofibroblastic derivation. At our 4 year follow-up, the patient remained free of local recurrence and surgery related complications. The clinicopathologic findings and the differential diagnosis of this lesion is presented and discussed.

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Titel: Collagenous Myofibroblastic Tumor of the Mandible: Case Report of a Unique Locally Aggressive Neoplasm
verfasst von: Jason W. Nash
Amy C. Hessel
Nadarajah Vigneswaran
Adel K. El-Naggar
Publikationsdatum: 01.03.2010
Verlag: Humana Press Inc
Erschienen in: Head and Neck Pathology / Ausgabe 1/2010
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-009-0154-x

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Collagenous Myofibroblastic Tumor of the Mandible: Case Report of a Unique Locally Aggressive Neoplasm

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

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