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Erschienen in:

01.06.2010 | Neuro

Comparison of 4 cm Z-axis and 16 cm Z-axis multidetector CT perfusion

verfasst von: Mark Page, Dee Nandurkar, Marcus Peter Crossett, Stephen L. Stuckey, Kenneth P. Lau, Nicholas Kenning, John M. Troupis

Erschienen in: European Radiology | Ausgabe 6/2010

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Abstract

Objective

The aim of the study was to compare 4 cm with 16 cm Z-axis coverage in the assessment of brain CT perfusion (CTP) using. 320 slice multidetector CT

Methods

A retrospective non-randomised review of CTP performed on MD320 CT between September 2008 and January 2009 was undertaken. Two experienced readers reviewed the studies along with the 4 cm and 16 cm Z-axis CTP image data set. The outcome parameters assessed were the extent of the original finding, any additional findings and a change of diagnosis.

Results

14 out of 27 patients were found to have abnormal CTP (mean age 58.1 years, 9 male). The 16 cm Z-axis increased the accuracy of the infarct core in 78% and ischaemic penumbra quantification in 100% of the cases. It also diagnosed additional infarcts in the same vascular territory in 28% of cases and in a different vascular territory in 14%.

Conclusions

The increased field of view with MD320 better defines the true extent of the infarct core and ischaemic penumbra. It also identified other areas of infarction that were not identified on the 4 cm Z-axis.

World Health Organization. The top ten causes of death. Available via WHO www.who.int/mediacentre/factsheets/fs310/en/index.html. Accessed 6 Apr 2009

National Institute of Neurological Diseases and Stroke rt-PA Stroke Study Group (1995) Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 333:1581–1587CrossRef

Wintermark M, Sesay M, Barbier E et al (2005) Comparative overview of brain perfusion imaging techniques. Stroke 36:e83–e99CrossRefPubMed

Latchaw RE, Yonas H, Hunter GJ et al (2003) Guidelines and recommendations for perfusion imaging in cerebral ischemia. Stroke 34:1084–1104CrossRefPubMed

Silvernnoinen HM, Hamberg LM, Lindberg PJ et al (2008) CT Perfusion identifies increased salvage of tissue in patients receiving intravenous recombinant tissue plasminogen activator within 3 hours of stroke onset. AJNR Am J Neuroradiol 29:1118–1123CrossRef

Hoeffner EG, Case I, Jain R et al (2004) Cerebral perfusion CT: technique and clinical applications. Radiology 231:632–644CrossRefPubMed

Konig K (2007) Diagnosis of acute stroke. In: Miles KA, Eastwood JD, Konig M (eds) Multidetector computed tomography in cerebrovascular disease, CT perfusion imaging. Informa Healthcare Ltd, Milton Park, pp 83–97

Miles KA, Menon DK (2007) Cerebrovascular physiology and pathophysiology. In: Miles KA, Eastwood JD, Konig M (eds) Multidetector computed tomography in cerebrovascular disease, CT perfusion imaging. Informa Healthcare, Milton Park, pp 71–82

Roberts HC, Roberts PL, Wade SS et al (2001) Multisection dynamic CT perfusion for acute cerebral ischemia: the “toggling-table” technique. AJNR Am J Neuroradiol 22:1077–1080PubMed

10.

Wintermark M, Maeder P, Verdun FR et al (2000) Using 80 kVp versus 120 kVp in perfusion CT measurement of regional cerebral blood flow. AJNR Am J Neuroradiol 21:1881–1884PubMed

11.

Konig M, Bultmann E, Bode-Schnurbus L et al (2007) Image quality in CT perfusion imaging of the brain, the role of iodine concentration. Eur Radiol 17:39–47CrossRefPubMed

12.

Wiesmann M, Berg S, Bohner G et al (2008) Dose reduction in dynamic perfusion CT of the brain: effects of the scan frequency on measurements of cerebral blood flow. Cerebral blood volume and mean transit time. Eur Radiol 18:2967–2974CrossRefPubMed

13.

Wintermark M, Smith WS, Nerissa U et al (2004) Dynamic perfusion CT: optimizing the temporal resolution and contrast volume calculation of perfusion CT parameters in stroke patients. AJNR Am J Neuroradiol 25:720–729PubMed

14.

Soustiel JF, Mor N, Zaaroor M et al (2006) Cerebral perfusion computerized tomography: influence of reference vessels, regions of interest and interobserver variability. Neuroradiology 48:670–677CrossRefPubMed

15.

Wintermark M, Fischbein NJ, Smith WS et al (2005) Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke. AJNR Am J Neuroradiol 26:104–112PubMed

16.

Eastwood JD, Lev MH, Wintermark M et al (2003) Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke. AJNR Am J Neuroradiol 24:1869–1875PubMed

17.

Ezzeddine MA, Lev MH, McDonald CT et al (2002) CT angiography with whole brain perfused blood volume imaging: added clinical value in the assessment of acute stroke. Stroke 33:959–966CrossRefPubMed

18.

Klingebiel R, Siebert E, Diekmann S et al (2009) 4-D Imaging in cerebrovascular disorders by using 320-slice CT: feasibility and preliminary clinical experience. Acad Radiol 16:123–129CrossRefPubMed

19.

Mori S, Obata T, Nakajima N et al (2005) Volumetric perfusion CT using prototype 256-detector row CT scanner: preliminary study with healthy porcine model. AJNR Am J Neuroradiol 26:2536–2541PubMed

20.

Provenzale JM, Shah K, Patel U et al (2008) Systemic review of CT and MR perfusion imaging for assessment of acute cerebrovascular disease. AJNR Am J Neuroradiol 29:1476–1482CrossRefPubMed

Titel: Comparison of 4 cm Z-axis and 16 cm Z-axis multidetector CT perfusion
verfasst von: Mark Page
Dee Nandurkar
Marcus Peter Crossett
Stephen L. Stuckey
Kenneth P. Lau
Nicholas Kenning
John M. Troupis
Publikationsdatum: 01.06.2010
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 6/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1688-8

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Comparison of 4 cm Z-axis and 16 cm Z-axis multidetector CT perfusion