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01.12.2024 | Image

Congenital Juvenile Xanthogranuloma in the Perioral Region: A Case Image

verfasst von: Andrea Maldonado, Rubén Muñoz, Nayari Alarcon, José Victor Lemos Ventura, Bruno Augusto Benevenuto de Andrade, Mariana Villarroel-Dorrego, José Alcides Almeida de Arruda

Erschienen in: Head and Neck Pathology | Ausgabe 1/2024

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Abstract

Juvenile xanthogranuloma (JXG) is the most common form of non-Langerhans cell histiocytosis in childhood. It often presents with cutaneous involvement and exhibits a predilection for the head and neck region. This article illustrates a case of congenital JXG in a 5-month-old boy, characterized by a solitary, well-circumscribed nodule above the left upper lip. Histopathologically, the lesion exhibited histiocytes with eosinophilic cytoplasm and Touton giant cells. Immunohistochemistry revealed histiocytes positive for CD68 and Factor XIIIa, while negative for S-100 protein. Clinicians should become familiar with the broad clinical spectrum of cutaneous JXG, particularly its congenital presentation, in order to ensure timely and accurate management.

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Titel: Congenital Juvenile Xanthogranuloma in the Perioral Region: A Case Image
verfasst von: Andrea Maldonado
Rubén Muñoz
Nayari Alarcon
José Victor Lemos Ventura
Bruno Augusto Benevenuto de Andrade
Mariana Villarroel-Dorrego
José Alcides Almeida de Arruda
Publikationsdatum: 01.12.2024
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2024
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-024-01649-y

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Congenital Juvenile Xanthogranuloma in the Perioral Region: A Case Image

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

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